MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Karolina, Dwi Setyowati ^a   Armugam, Arunmozhiarasi ^a   Tavintharan, Subramaniam ^b   Wong, Michael T K ^b   Lim, Su Chi ^b   Sum, Chee Fang ^b   Jeyaseelan, Kandiah ^a,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b KHOO TECK PUAT HOSPITAL   (Singapore)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MICRORNA; MICRORNA 144; MICRORNA 146A; MICRORNA 150; MICRORNA 182; MICRORNA 192; MICRORNA 29A; MICRORNA 30D; MICRORNA 320A; UNCLASSIFIED DRUG; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; MIRN144 MICRORNA, HUMAN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DOWN REGULATION; ERYTHROPOIESIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; HORMONE INHIBITION; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORAL GLUCOSE TOLERANCE TEST; PATHOGENESIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RAT; RNA ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BLOOD; DISEASE MODEL; DNA MICROARRAY; GENETICS; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; VALIDATION STUDY; WISTAR RAT;

RATTUS;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MALE; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 79960932477     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022839     Document Type: Article

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