Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling

British Journal of Nutrition

Volumn 107, Issue 2, 2012, Pages 229-241

  Wang, Zhen ^a   Liu, Dexiang ^a   Wang, Fuwu ^a   Liu, Shangming ^a   Zhao, Shidou ^a   Ling, Eng Ang ^b   Hao, Aijun ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Microglia; NF B; SFA; Toll like receptor 4

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NEUTRALIZING ANTIBODY; NITRIC OXIDE; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; STEARIC ACID; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FATTY ACID ANALYSIS; IN VITRO STUDY; INTRACELLULAR SIGNALING; MICROGLIA; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIMARY CELL CULTURE; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION;

ANIMALS; APOPTOSIS; CELL LINE; CELLS, CULTURED; CYTOKINES; GENES, REPORTER; MICE; MICE, INBRED BALB C; MICROGLIA; NERVE TISSUE PROTEINS; NITRIC OXIDE SYNTHASE TYPE II; PALMITIC ACID; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEARIC ACIDS; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; UP-REGULATION;

EID: 84862928989     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511002868     Document Type: Article

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