Lipopolysaccharide interaction with cell surface toll-like receptor 4-MD-2: Higher affinity than that with MD-2 or CD14

Journal of Experimental Medicine

Volumn 198, Issue 7, 2003, Pages 1035-1042

  Akashi, Sachiko ^a   Saitoh, Shin Ichiroh ^a   Wakabayashi, Yasutaka ^a   Kikuchi, Takane ^a   Takamura, Noriaki ^a   Nagai, Yoshinori ^a   Kusumoto, Yutaka ^a   Fukase, Koichi ^b   Kusumoto, Shoichi ^b   Adachi, Yoshiyuki ^c   Kosugi, Atsushi ^b,d   Miyake, Kensuke ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Activation; Cell surface molecule; Innate immunity; Macrophage

Indexed keywords

CD14 ANTIGEN; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; E 5531; ENDOTOXIN; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CELL INTERACTION; COMPLEX FORMATION; DISSOCIATION CONSTANT; GRAM NEGATIVE BACTERIUM; IMMUNE RESPONSE; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD14; ANTIGENS, SURFACE; LIPID A; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MEMBRANE GLYCOPROTEINS; MICE; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0141890200     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20031076     Document Type: Article

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