A Mechanistic Understanding of Pyroptosis: The Fiery Death Triggered by Invasive Infection

Advances in Immunology

Volumn 135, Issue , 2017, Pages 81-117

  Liu, Xing ^a   Lieberman, Judy ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Gasdermin; Inflammasome; Inflammatory caspases; Pore forming protein; Pyroptosis; Sepsis

Indexed keywords

CASPASE 11; CASPASE 4; CASPASE 5; GASDERMIN A; GASDERMIN B; GASDERMIN C; GASDERMIN D; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MEMBRANE PROTEIN; NACHT LEUCINE RICH REPEAT AND PYRIN DOMAIN CONTAINING PROTEIN 1; NACHT LEUCINE RICH REPEAT AND PYRIN DOMAIN CONTAINING PROTEIN 12; NACHT LEUCINE RICH REPEAT AND PYRIN DOMAIN CONTAINING PROTEIN 3; NACHT LEUCINE RICH REPEAT AND PYRIN DOMAIN CONTAINING PROTEIN 6; NACHT LEUCINE RICH REPEAT AND PYRIN DOMAIN CONTAINING PROTEIN 7; NAIP/NLRC4 COMPLEX; PYRIN; UNCLASSIFIED DRUG; CASPASE; CYTOKINE; GSDMD PROTEIN, HUMAN; ISOPROTEIN; TUMOR PROTEIN;

AMINO TERMINAL SEQUENCE; BACILLUS MEGATERIUM; BACTERIAL IMMUNITY; BACTERICIDAL ACTIVITY; CELL DEATH; CYTOKINE RELEASE; DFNA5 GENE; DFNB59 GENE; ESCHERICHIA COLI; GENE; GENE OVEREXPRESSION; GSDMA GENE; GSDMB GENE; GSDMC GENE; GSDMD GENE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INNATE IMMUNITY; LISTERIA; NONHUMAN; NUCLEAR PORE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; PYROPTOSIS; SALMONELLA; SEPSIS; STAPHYLOCOCCUS AUREUS; ANIMAL; ANTIGEN PRESENTING CELL; BACTERIAL INFECTION; CELL MEMBRANE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MICROBIOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

ANIMALS; ANTIGEN-PRESENTING CELLS; BACTERIAL INFECTIONS; CASPASES; CELL MEMBRANE; CYTOKINES; GENE EXPRESSION REGULATION; HIV INFECTIONS; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; NEOPLASM PROTEINS; PROTEIN ISOFORMS; PYROPTOSIS; SEPSIS; SIGNAL TRANSDUCTION;

EID: 85017142478     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/bs.ai.2017.02.002     Document Type: Chapter

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