-
1
-
-
0037136311
-
Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation
-
K.N. Balaji, N. Schaschke, W. Machleidt, M. Catalfamo, and P.A. Henkart Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation J. Exp. Med. 196 2002 493 503
-
(2002)
J. Exp. Med.
, vol.196
, pp. 493-503
-
-
Balaji, K.N.1
Schaschke, N.2
MacHleidt, W.3
Catalfamo, M.4
Henkart, P.A.5
-
2
-
-
0033137079
-
Granzyme a loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
-
P.J. Beresford, Z. Xia, A.H. Greenberg, and J. Lieberman Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation Immunity 10 1999 585 594
-
(1999)
Immunity
, vol.10
, pp. 585-594
-
-
Beresford, P.J.1
Xia, Z.2
Greenberg, A.H.3
Lieberman, J.4
-
3
-
-
0029609143
-
Calcium-regulated exocytosis is required for cell membrane resealing
-
G.Q. Bi, J.M. Alderton, and R.A. Steinhardt Calcium-regulated exocytosis is required for cell membrane resealing J. Cell Biol. 131 1995 1747 1758
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1747-1758
-
-
Bi, G.Q.1
Alderton, J.M.2
Steinhardt, R.A.3
-
4
-
-
0031587308
-
Channel formation and [Ca2+]i accumulation induced by perforin N-terminus peptides: Comparison with purified perforin and whole lytic granules
-
O. Binah, C.C. Liu, J.D. Young, and G. Berke Channel formation and [Ca2+]i accumulation induced by perforin N-terminus peptides: comparison with purified perforin and whole lytic granules Biochem. Biophys. Res. Commun. 240 1997 647 650
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 647-650
-
-
Binah, O.1
Liu, C.C.2
Young, J.D.3
Berke, G.4
-
5
-
-
0033499729
-
Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin
-
K.A. Browne, E. Blink, V.R. Sutton, C.J. Froelich, D.A. Jans, and J.A. Trapani Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin Mol. Cell. Biol. 19 1999 8604 8615
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8604-8615
-
-
Browne, K.A.1
Blink, E.2
Sutton, V.R.3
Froelich, C.J.4
Jans, D.A.5
Trapani, J.A.6
-
6
-
-
0141741400
-
Perforin and the granule exocytosis cytotoxicity pathway
-
M. Catalfamo, and P.A. Henkart Perforin and the granule exocytosis cytotoxicity pathway Curr. Opin. Immunol. 15 2003 522 527
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 522-527
-
-
Catalfamo, M.1
Henkart, P.A.2
-
7
-
-
10544252275
-
New paradigm for lymphocyte granule-mediated cytotoxicity
-
C.J. Froelich, K. Orth, J. Turbov, P. Seth, R. Gottlieb, B. Babior, G.M. Shah, R.C. Bleackley, V.M. Dixit, and W. Hanna New paradigm for lymphocyte granule-mediated cytotoxicity J. Biol. Chem. 271 1996 29073 29079
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29073-29079
-
-
Froelich, C.J.1
Orth, K.2
Turbov, J.3
Seth, P.4
Gottlieb, R.5
Babior, B.6
Shah, G.M.7
Bleackley, R.C.8
Dixit, V.M.9
Hanna, W.10
-
8
-
-
0036143018
-
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation
-
M.L. Huynh, V.A. Fadok, and P.M. Henson Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation J. Clin. Invest. 109 2002 41 50
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 41-50
-
-
Huynh, M.L.1
Fadok, V.A.2
Henson, P.M.3
-
9
-
-
0028219791
-
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
-
D. Kagi, B. Ledermann, K. Burki, P. Seiler, B. Odermatt, K.J. Olsen, E.R. Podack, R.M. Zinkernagel, and H. Hengartner Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice Nature 369 1994 31 37
-
(1994)
Nature
, vol.369
, pp. 31-37
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Seiler, P.4
Odermatt, B.5
Olsen, K.J.6
Podack, E.R.7
Zinkernagel, R.M.8
Hengartner, H.9
-
10
-
-
0034192109
-
Cell death-associated translocation of plasma membrane components induced by CTL
-
Y. Kawasaki, T. Saito, Y. Shirota-Someya, Y. Ikegami, H. Komano, M.H. Lee, C.J. Froelich, N. Shinohara, and H. Takayama Cell death-associated translocation of plasma membrane components induced by CTL J. Immunol. 164 2000 4641 4648
-
(2000)
J. Immunol.
, vol.164
, pp. 4641-4648
-
-
Kawasaki, Y.1
Saito, T.2
Shirota-Someya, Y.3
Ikegami, Y.4
Komano, H.5
Lee, M.H.6
Froelich, C.J.7
Shinohara, N.8
Takayama, H.9
-
11
-
-
1642389211
-
Killing of target cells by redirected granzyme B in the absence of perforin
-
F.C. Kurschus, M. Kleinschmidt, E. Fellows, K. Dornmair, R. Rudolph, H. Lilie, and D.E. Jenne Killing of target cells by redirected granzyme B in the absence of perforin FEBS Lett. 562 2004 87 92
-
(2004)
FEBS Lett.
, vol.562
, pp. 87-92
-
-
Kurschus, F.C.1
Kleinschmidt, M.2
Fellows, E.3
Dornmair, K.4
Rudolph, R.5
Lilie, H.6
Jenne, D.E.7
-
12
-
-
0038725690
-
Cell death and immunity: The ABCs of granule-mediated cytotoxicity: New weapons in the arsenal
-
J. Lieberman Cell death and immunity: the ABCs of granule-mediated cytotoxicity: new weapons in the arsenal Nat. Rev. Immunol. 3 2003 361 370
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 361-370
-
-
Lieberman, J.1
-
13
-
-
15244351845
-
Granzyme a induces caspase-independent mitochondrial damage, a required first step for apoptosis
-
D. Martinvalet, P. Zhu, and J. Lieberman Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis Immunity 22 2005 355 370
-
(2005)
Immunity
, vol.22
, pp. 355-370
-
-
Martinvalet, D.1
Zhu, P.2
Lieberman, J.3
-
14
-
-
0022253052
-
Isolation of a lytic pore forming protein (perforin) from cytolytic T cells
-
D. Masson, and J. Tschopp Isolation of a lytic pore forming protein (perforin) from cytolytic T cells J. Biol. Chem. 260 1985 9069 9073
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 9069-9073
-
-
Masson, D.1
Tschopp, J.2
-
15
-
-
0344824647
-
Plasma membrane disruption: Repair, prevention, adaptation
-
P.L. McNeil, and R.A. Steinhardt Plasma membrane disruption: repair, prevention, adaptation Annu. Rev. Cell Dev. Biol. 19 2003 697 731
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 697-731
-
-
McNeil, P.L.1
Steinhardt, R.A.2
-
16
-
-
0036195424
-
Cytotoxic cell granule-mediated apoptosis: Perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation
-
S.S. Metkar, B. Wang, M. Aguilar-Santelises, S.M. Raja, L. Uhlin-Hansen, E. Podack, J.A. Trapani, and C.J. Froelich Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation Immunity 16 2002 417 428
-
(2002)
Immunity
, vol.16
, pp. 417-428
-
-
Metkar, S.S.1
Wang, B.2
Aguilar-Santelises, M.3
Raja, S.M.4
Uhlin-Hansen, L.5
Podack, E.6
Trapani, J.A.7
Froelich, C.J.8
-
17
-
-
0021273768
-
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors
-
P.J. Millard, M.P. Henkart, C.W. Reynolds, and P.A. Henkart Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors J. Immunol. 132 1984 3197 3204
-
(1984)
J. Immunol.
, vol.132
, pp. 3197-3204
-
-
Millard, P.J.1
Henkart, M.P.2
Reynolds, C.W.3
Henkart, P.A.4
-
18
-
-
0029585288
-
Vesicle accumulation and exocytosis at sites of plasma membrane disruption
-
K. Miyake, and P.L. McNeil Vesicle accumulation and exocytosis at sites of plasma membrane disruption J. Cell Biol. 131 1995 1737 1745
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1737-1745
-
-
Miyake, K.1
McNeil, P.L.2
-
19
-
-
0034721646
-
Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis
-
B. Motyka, G. Korbutt, M.J. Pinkoski, J.A. Heibein, A. Caputo, M. Hobman, M. Barry, I. Shostak, T. Sawchuk, and C.F. Holmes Mannose 6-phosphate/insulin- like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis Cell 103 2000 491 500
-
(2000)
Cell
, vol.103
, pp. 491-500
-
-
Motyka, B.1
Korbutt, G.2
Pinkoski, M.J.3
Heibein, J.A.4
Caputo, A.5
Hobman, M.6
Barry, M.7
Shostak, I.8
Sawchuk, T.9
Holmes, C.F.10
-
20
-
-
0032147225
-
Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis
-
M.J. Pinkoski, M. Hobman, J.A. Heibein, K. Tomaselli, F. Li, P. Seth, C.J. Froelich, and R.C. Bleackley Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis Blood 92 1998 1044 1054
-
(1998)
Blood
, vol.92
, pp. 1044-1054
-
-
Pinkoski, M.J.1
Hobman, M.2
Heibein, J.A.3
Tomaselli, K.4
Li, F.5
Seth, P.6
Froelich, C.J.7
Bleackley, R.C.8
-
21
-
-
0001041396
-
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T cell granules
-
E.R. Podack, J.D.-E. Young, and Z.A. Cohn Isolation and biochemical and functional characterization of perforin 1 from cytolytic T cell granules Proc. Natl. Acad. Sci. USA 82 1985 8629 8633
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 8629-8633
-
-
Podack, E.R.1
Young, J.D.-E.2
Cohn, Z.A.3
-
22
-
-
0023395751
-
Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets
-
M. Poenie, R.Y. Tsien, and A.M. Schmitt-Verhulst Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets EMBO J. 6 1987 2223 2232
-
(1987)
EMBO J.
, vol.6
, pp. 2223-2232
-
-
Poenie, M.1
Tsien, R.Y.2
Schmitt-Verhulst, A.M.3
-
23
-
-
0035958557
-
Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes
-
A. Reddy, E.V. Caler, and N.W. Andrews Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes Cell 106 2001 157 169
-
(2001)
Cell
, vol.106
, pp. 157-169
-
-
Reddy, A.1
Caler, E.V.2
Andrews, N.W.3
-
24
-
-
0030615262
-
Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells
-
A. Rodriguez, P. Webster, J. Ortego, and N.W. Andrews Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells J. Cell Biol. 137 1997 93 104
-
(1997)
J. Cell Biol.
, vol.137
, pp. 93-104
-
-
Rodriguez, A.1
Webster, P.2
Ortego, J.3
Andrews, N.W.4
-
25
-
-
0018843454
-
Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement
-
J.H. Russell, V.R. Masakowski, and C.B. Dobos Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement J. Immunol. 124 1980 1100 1105
-
(1980)
J. Immunol.
, vol.124
, pp. 1100-1105
-
-
Russell, J.H.1
Masakowski, V.R.2
Dobos, C.B.3
-
26
-
-
0026060951
-
Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis
-
H. Sauer, L. Pratsch, J. Tschopp, S. Bhakdi, and R. Peters Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis Biochim. Biophys. Acta 1063 1991 137 146
-
(1991)
Biochim. Biophys. Acta
, vol.1063
, pp. 137-146
-
-
Sauer, H.1
Pratsch, L.2
Tschopp, J.3
Bhakdi, S.4
Peters, R.5
-
27
-
-
0026532606
-
A natural killer cell granule protein that induces DNA fragmentation and apoptosis
-
L. Shi, R.P. Kraut, R. Aebersold, and A.H. Greenberg A natural killer cell granule protein that induces DNA fragmentation and apoptosis J. Exp. Med. 175 1992 553 566
-
(1992)
J. Exp. Med.
, vol.175
, pp. 553-566
-
-
Shi, L.1
Kraut, R.P.2
Aebersold, R.3
Greenberg, A.H.4
-
28
-
-
0030892138
-
Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization
-
L. Shi, S. Mai, S. Israels, K. Browne, J.A. Trapani, and A.H. Greenberg Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization J. Exp. Med. 185 1997 855 866
-
(1997)
J. Exp. Med.
, vol.185
, pp. 855-866
-
-
Shi, L.1
Mai, S.2
Israels, S.3
Browne, K.4
Trapani, J.A.5
Greenberg, A.H.6
-
30
-
-
17844380811
-
Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis
-
L. Shi, D. Keefe, E. Durand, H. Feng, D. Zhang, and J. Lieberman Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis J. Immunol. 174 2005 5456 5461
-
(2005)
J. Immunol.
, vol.174
, pp. 5456-5461
-
-
Shi, L.1
Keefe, D.2
Durand, E.3
Feng, H.4
Zhang, D.5
Lieberman, J.6
-
31
-
-
0028014529
-
Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release
-
R.A. Steinhardt, G. Bi, and J.M. Alderton Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release Science 263 1994 390 393
-
(1994)
Science
, vol.263
, pp. 390-393
-
-
Steinhardt, R.A.1
Bi, G.2
Alderton, J.M.3
-
32
-
-
0033520970
-
Perforin gene defects in familial hemophagocytic lymphohistiocytosis
-
S.E. Stepp, R. Dufourcq-Lagelouse, F. Le Deist, S. Bhawan, S. Certain, P.A. Mathew, J.I. Henter, M. Bennett, A. Fischer, G. de Saint Basile, and V. Kumar Perforin gene defects in familial hemophagocytic lymphohistiocytosis Science 286 1999 1957 1959
-
(1999)
Science
, vol.286
, pp. 1957-1959
-
-
Stepp, S.E.1
Dufourcq-Lagelouse, R.2
Le Deist, F.3
Bhawan, S.4
Certain, S.5
Mathew, P.A.6
Henter, J.I.7
Bennett, M.8
Fischer, A.9
De Saint Basile, G.10
Kumar, V.11
-
33
-
-
0035655587
-
The immunological synapse of CTL contains a secretory domain and membrane bridges
-
J.C. Stinchcombe, G. Bossi, S. Booth, and G.M. Griffiths The immunological synapse of CTL contains a secretory domain and membrane bridges Immunity 15 2001 751 761
-
(2001)
Immunity
, vol.15
, pp. 751-761
-
-
Stinchcombe, J.C.1
Bossi, G.2
Booth, S.3
Griffiths, G.M.4
-
34
-
-
0037455545
-
A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death
-
J.A. Trapani, V.R. Sutton, K.Y. Thia, Y.Q. Li, C.J. Froelich, D.A. Jans, M.S. Sandrin, and K.A. Browne A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death J. Cell Biol. 160 2003 223 233
-
(2003)
J. Cell Biol.
, vol.160
, pp. 223-233
-
-
Trapani, J.A.1
Sutton, V.R.2
Thia, K.Y.3
Li, Y.Q.4
Froelich, C.J.5
Jans, D.A.6
Sandrin, M.S.7
Browne, K.A.8
-
35
-
-
0022466507
-
Structural/functional similarity between proteins involved in complement- and cytotoxic T-lymphocyte-mediated cytolysis
-
J. Tschopp, D. Masson, and K.K. Stanley Structural/functional similarity between proteins involved in complement- and cytotoxic T-lymphocyte-mediated cytolysis Nature 322 1986 831 834
-
(1986)
Nature
, vol.322
, pp. 831-834
-
-
Tschopp, J.1
Masson, D.2
Stanley, K.K.3
-
36
-
-
2342514099
-
The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis
-
K. Veugelers, B. Motyka, C. Frantz, I. Shostak, T. Sawchuk, and R.C. Bleackley The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis Blood 103 2004 3845 3853
-
(2004)
Blood
, vol.103
, pp. 3845-3853
-
-
Veugelers, K.1
Motyka, B.2
Frantz, C.3
Shostak, I.4
Sawchuk, T.5
Bleackley, R.C.6
-
37
-
-
0032512565
-
Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system
-
Z. Xia, C.M. Kam, C. Huang, J.C. Powers, R.J. Mandle, R.L. Stevens, and J. Lieberman Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system Biochem. Biophys. Res. Commun. 243 1998 384 389
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.243
, pp. 384-389
-
-
Xia, Z.1
Kam, C.M.2
Huang, C.3
Powers, J.C.4
Mandle, R.J.5
Stevens, R.L.6
Lieberman, J.7
-
38
-
-
0022570037
-
Functional channel formation associated with cytotoxic T-cell granules
-
J.D. Young, C.F. Nathan, E.R. Podack, M.A. Palladino, and Z.A. Cohn Functional channel formation associated with cytotoxic T-cell granules Proc. Natl. Acad. Sci. USA 83 1986 150 154
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 150-154
-
-
Young, J.D.1
Nathan, C.F.2
Podack, E.R.3
Palladino, M.A.4
Cohn, Z.A.5
|