The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

PLoS Pathogens

Volumn 12, Issue 12, 2016, Pages

  Ratner, Dmitry ^a   Orning, M Pontus A ^a,b   Proulx, Megan K ^a   Wang, Donghai ^a,c   Gavrilin, Mikhail A ^d   Wewers, Mark D ^d   Alnemri, Emad S ^e   Johnson, Peter F ^f   Lee, Bettina ^g   Mecsas, Joan ^h   Kayagaki, Nobuhiko ^g   Goguen, Jon D ^a   Lien, Egil ^a,b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g GENENTECH INC   (United States)

^h TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CASPASE 8; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN; PROTEIN KINASE; PYRIN; S6 KINASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VIRULENCE FACTOR; YERSINIA OUTER PROTEIN E; YERSINIA OUTER PROTEIN M; OUTER MEMBRANE PROTEIN; YOPM PROTEIN, YERSINIA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PYROPTOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SURVIVAL; TYPE III SECRETION SYSTEM; WESTERN BLOTTING; YERSINIA PESTIS; ANIMAL; DISEASE MODEL; IMMUNOLOGY; KNOCKOUT MOUSE; PLAGUE;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; DISEASE MODELS, ANIMAL; INFLAMMASOMES; MICE; MICE, KNOCKOUT; PLAGUE; PYRIN; YERSINIA PESTIS;

EID: 85007586393     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006035     Document Type: Article

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