-
1
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt MF, et al. (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448(7152):470-473.
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 470-473
-
-
Moffatt, M.F.1
-
2
-
-
69449101386
-
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease
-
Verlaan DJ, et al. (2009) Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet 85(3):377-393.
-
(2009)
Am J Hum Genet
, vol.85
, Issue.3
, pp. 377-393
-
-
Verlaan, D.J.1
-
3
-
-
0028230946
-
Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
-
Marsh DG, et al. (1994) Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 264(5162):1152-1156.
-
(1994)
Science
, vol.264
, Issue.5162
, pp. 1152-1156
-
-
Marsh, D.G.1
-
4
-
-
84867375353
-
ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6
-
Miller M, et al. (2012) ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proc Natl Acad Sci USA 109(41):16648-16653.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.41
, pp. 16648-16653
-
-
Miller, M.1
-
5
-
-
84898632756
-
ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma
-
Miller M, et al. (2014) ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. J Immunol 192(8):3475-3487.
-
(2014)
J Immunol
, vol.192
, Issue.8
, pp. 3475-3487
-
-
Miller, M.1
-
6
-
-
0033851634
-
Gasdermin (Gsdm) localizing to mouse chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells
-
Saeki N, Kuwahara Y, Sasaki H, Satoh H, Shiroishi T (2000) Gasdermin (Gsdm) localizing to mouse chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells. Mamm Genome 11(9):718-724.
-
(2000)
Mamm Genome
, vol.11
, Issue.9
, pp. 718-724
-
-
Saeki, N.1
Kuwahara, Y.2
Sasaki, H.3
Satoh, H.4
Shiroishi, T.5
-
7
-
-
84899877856
-
Gasdermin-B promotes invasion and metastasis in breast cancer cells
-
Hergueta-Redondo M, et al. (2014) Gasdermin-B promotes invasion and metastasis in breast cancer cells. PLoS One 9(3):e90099.
-
(2014)
PLoS One
, vol.9
, Issue.3
-
-
Hergueta-Redondo, M.1
-
8
-
-
62449114842
-
Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma
-
Wu H, et al. (2009) Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Allergy 64(4):629-635.
-
(2009)
Allergy
, vol.64
, Issue.4
, pp. 629-635
-
-
Wu, H.1
-
9
-
-
74449091631
-
Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways
-
Madore A-M, et al. (2010) Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways. Hum Immunol 71(2):144-150.
-
(2010)
Hum Immunol
, vol.71
, Issue.2
, pp. 144-150
-
-
Madore, A.-M.1
-
10
-
-
67650081844
-
Expression of GSDML associates with tumor progression in uterine cervix cancer
-
Sun Q, et al. (2008) Expression of GSDML associates with tumor progression in uterine cervix cancer. Transl Oncol 1(2):73-83.
-
(2008)
Transl Oncol
, vol.1
, Issue.2
, pp. 73-83
-
-
Sun, Q.1
-
11
-
-
33746215177
-
Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling
-
Shim YM, et al. (2006) Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling. J Immunol 177(3):1918-1924.
-
(2006)
J Immunol
, vol.177
, Issue.3
, pp. 1918-1924
-
-
Shim, Y.M.1
-
12
-
-
84863393701
-
Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines
-
Bossley CJ, et al. (2012) Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines. J Allergy Clin Immunol 129(4):974-82.e13.
-
(2012)
J Allergy Clin Immunol
, vol.129
, Issue.4
, pp. 974-982.e13
-
-
Bossley, C.J.1
-
13
-
-
84875732224
-
Increased airway smooth muscle in preschool wheezers who have asthma at school age
-
O'Reilly R, et al. (2013) Increased airway smooth muscle in preschool wheezers who have asthma at school age. J Allergy Clin Immunol 131(4):1024-1032, 1032.e1-16.
-
(2013)
J Allergy Clin Immunol
, vol.131
, Issue.4
-
-
O'Reilly, R.1
-
14
-
-
84922595423
-
Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling
-
Noble PB, et al. (2014) Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling. Pulm Pharmacol Ther 29(2):96-107.
-
(2014)
Pulm Pharmacol Ther
, vol.29
, Issue.2
, pp. 96-107
-
-
Noble, P.B.1
-
15
-
-
84914170420
-
TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis
-
Beppu LY, et al. (2014) TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis. J Allergy Clin Immunol 134(5):1100-1107.e4.
-
(2014)
J Allergy Clin Immunol
, vol.134
, Issue.5
, pp. 1100-1107.e4
-
-
Beppu, L.Y.1
-
16
-
-
29944436527
-
Leukotriene C4 induces TGF-beta1 production in airway epithelium via p38 kinase pathway
-
Perng DW, et al. (2006) Leukotriene C4 induces TGF-beta1 production in airway epithelium via p38 kinase pathway. Am J Respir Cell Mol Biol 34(1):101-107.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, Issue.1
, pp. 101-107
-
-
Perng, D.W.1
-
17
-
-
79551551534
-
Role of transforming growth factor-β in airway remodeling in asthma
-
Halwani R, Al-Muhsen S, Al-Jahdali H, Hamid Q (2011) Role of transforming growth factor-β in airway remodeling in asthma. Am J Respir Cell Mol Biol 44(2):127-133.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, Issue.2
, pp. 127-133
-
-
Halwani, R.1
Al-Muhsen, S.2
Al-Jahdali, H.3
Hamid, Q.4
-
18
-
-
84899741687
-
MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis
-
Das S, et al. (2014) MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis. Am J Respir Cell Mol Biol 50(5):882-892.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, Issue.5
, pp. 882-892
-
-
Das, S.1
-
19
-
-
0031280307
-
Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by alveolar macrophages of asthmatics
-
Mautino G, Oliver N, Chanez P, Bousquet J, Capony F (1997) Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by alveolar macrophages of asthmatics. Am J Respir Cell Mol Biol 17(5):583-591.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, Issue.5
, pp. 583-591
-
-
Mautino, G.1
Oliver, N.2
Chanez, P.3
Bousquet, J.4
Capony, F.5
-
20
-
-
0036469065
-
Signal transduction and the control of gene expression
-
Brivanlou AH, Darnell JE, Jr (2002) Signal transduction and the control of gene expression. Science 295(5556):813-818.
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 813-818
-
-
Brivanlou, A.H.1
Darnell, J.E.2
-
21
-
-
84923276179
-
RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease
-
Xiong HY, et al. (2015) RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. Science 347(6218):1254806.
-
(2015)
Science
, vol.347
, Issue.6218
-
-
Xiong, H.Y.1
-
23
-
-
34447560054
-
Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4
-
Jame AJ, et al. (2007) Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4. Clin Exp Allergy 37(6):880-892.
-
(2007)
Clin Exp Allergy
, vol.37
, Issue.6
, pp. 880-892
-
-
Jame, A.J.1
-
24
-
-
0035523289
-
Role of chemokines in the pathogenesis of asthma
-
Lukacs NW (2001) Role of chemokines in the pathogenesis of asthma. Nat Rev Immunol 1(2):108-116.
-
(2001)
Nat Rev Immunol
, vol.1
, Issue.2
, pp. 108-116
-
-
Lukacs, N.W.1
-
25
-
-
84904670489
-
CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations
-
Rohde G, et al. (2014) CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations. Clin Exp Allergy 44(7):930-939.
-
(2014)
Clin Exp Allergy
, vol.44
, Issue.7
, pp. 930-939
-
-
Rohde, G.1
-
26
-
-
84862626656
-
CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity
-
Burkhardt AM, et al. (2012) CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity. J Immunol 188(12):6399-6406.
-
(2012)
J Immunol
, vol.188
, Issue.12
, pp. 6399-6406
-
-
Burkhardt, A.M.1
-
27
-
-
84912032596
-
Epithelial function and dysfunction in asthma
-
Loxham M, Davies DE, Blume C (2014) Epithelial function and dysfunction in asthma. Clin Exp Allergy 44(11):1299-1313.
-
(2014)
Clin Exp Allergy
, vol.44
, Issue.11
, pp. 1299-1313
-
-
Loxham, M.1
Davies, D.E.2
Blume, C.3
-
28
-
-
44449150336
-
ORMDL3 gene is associated with asthma in three ethnically diverse populations
-
Galanter J, et al. (2008) ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med 177(11):1194-1200.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, Issue.11
, pp. 1194-1200
-
-
Galanter, J.1
-
29
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt MF, et al.; GABRIEL Consortium (2010) A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 363(13):1211-1221.
-
(2010)
N Engl J Med
, vol.363
, Issue.13
, pp. 1211-1221
-
-
Moffatt, M.F.1
-
30
-
-
84943537300
-
Fstl1 promotes asthmatic airway remodeling by inducing oncostatin M
-
Miller M, et al. (2015) Fstl1 promotes asthmatic airway remodeling by inducing oncostatin M. J Immunol 195(8):3546-3556.
-
(2015)
J Immunol
, vol.195
, Issue.8
, pp. 3546-3556
-
-
Miller, M.1
-
31
-
-
84961233541
-
Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma
-
Miller M, et al. (2016) Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma. J Allergy Clin Immunol 138(2):596-599.e4.
-
(2016)
J Allergy Clin Immunol
, vol.138
, Issue.2
, pp. 596-599.e4
-
-
Miller, M.1
-
32
-
-
84930074657
-
The Phyre2 web portal for protein modeling, prediction and analysis
-
Kelley LA, Mezulis S, Yates CM, Wass MN, Sternberg MJE (2015) The Phyre2 web portal for protein modeling, prediction and analysis. Nat Protoc 10(6):845-858.
-
(2015)
Nat Protoc
, vol.10
, Issue.6
, pp. 845-858
-
-
Kelley, L.A.1
Mezulis, S.2
Yates, C.M.3
Wass, M.N.4
Sternberg, M.J.E.5
|