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Volumn 113, Issue 46, 2016, Pages 13132-13137

GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation

Author keywords

Airway hyperresponsiveness; Asthma; GSDMB; Inflammation; Remodeling

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; GASDERMIN B; PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; COLLAGEN; CYTOKINE; GELATINASE B; GSDMB PROTEIN, HUMAN; HOUSE DUST ALLERGEN; MESSENGER RNA; TUMOR PROTEIN;

EID: 84994813356     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1610433113     Document Type: Article
Times cited : (151)

References (32)
  • 1
    • 34547216747 scopus 로고    scopus 로고
    • Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
    • Moffatt MF, et al. (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448(7152):470-473.
    • (2007) Nature , vol.448 , Issue.7152 , pp. 470-473
    • Moffatt, M.F.1
  • 2
    • 69449101386 scopus 로고    scopus 로고
    • Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease
    • Verlaan DJ, et al. (2009) Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet 85(3):377-393.
    • (2009) Am J Hum Genet , vol.85 , Issue.3 , pp. 377-393
    • Verlaan, D.J.1
  • 3
    • 0028230946 scopus 로고
    • Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
    • Marsh DG, et al. (1994) Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 264(5162):1152-1156.
    • (1994) Science , vol.264 , Issue.5162 , pp. 1152-1156
    • Marsh, D.G.1
  • 4
    • 84867375353 scopus 로고    scopus 로고
    • ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6
    • Miller M, et al. (2012) ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proc Natl Acad Sci USA 109(41):16648-16653.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.41 , pp. 16648-16653
    • Miller, M.1
  • 5
    • 84898632756 scopus 로고    scopus 로고
    • ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma
    • Miller M, et al. (2014) ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. J Immunol 192(8):3475-3487.
    • (2014) J Immunol , vol.192 , Issue.8 , pp. 3475-3487
    • Miller, M.1
  • 6
    • 0033851634 scopus 로고    scopus 로고
    • Gasdermin (Gsdm) localizing to mouse chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells
    • Saeki N, Kuwahara Y, Sasaki H, Satoh H, Shiroishi T (2000) Gasdermin (Gsdm) localizing to mouse chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells. Mamm Genome 11(9):718-724.
    • (2000) Mamm Genome , vol.11 , Issue.9 , pp. 718-724
    • Saeki, N.1    Kuwahara, Y.2    Sasaki, H.3    Satoh, H.4    Shiroishi, T.5
  • 7
    • 84899877856 scopus 로고    scopus 로고
    • Gasdermin-B promotes invasion and metastasis in breast cancer cells
    • Hergueta-Redondo M, et al. (2014) Gasdermin-B promotes invasion and metastasis in breast cancer cells. PLoS One 9(3):e90099.
    • (2014) PLoS One , vol.9 , Issue.3
    • Hergueta-Redondo, M.1
  • 8
    • 62449114842 scopus 로고    scopus 로고
    • Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma
    • Wu H, et al. (2009) Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Allergy 64(4):629-635.
    • (2009) Allergy , vol.64 , Issue.4 , pp. 629-635
    • Wu, H.1
  • 9
    • 74449091631 scopus 로고    scopus 로고
    • Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways
    • Madore A-M, et al. (2010) Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways. Hum Immunol 71(2):144-150.
    • (2010) Hum Immunol , vol.71 , Issue.2 , pp. 144-150
    • Madore, A.-M.1
  • 10
    • 67650081844 scopus 로고    scopus 로고
    • Expression of GSDML associates with tumor progression in uterine cervix cancer
    • Sun Q, et al. (2008) Expression of GSDML associates with tumor progression in uterine cervix cancer. Transl Oncol 1(2):73-83.
    • (2008) Transl Oncol , vol.1 , Issue.2 , pp. 73-83
    • Sun, Q.1
  • 11
    • 33746215177 scopus 로고    scopus 로고
    • Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling
    • Shim YM, et al. (2006) Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling. J Immunol 177(3):1918-1924.
    • (2006) J Immunol , vol.177 , Issue.3 , pp. 1918-1924
    • Shim, Y.M.1
  • 12
    • 84863393701 scopus 로고    scopus 로고
    • Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines
    • Bossley CJ, et al. (2012) Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines. J Allergy Clin Immunol 129(4):974-82.e13.
    • (2012) J Allergy Clin Immunol , vol.129 , Issue.4 , pp. 974-982.e13
    • Bossley, C.J.1
  • 13
    • 84875732224 scopus 로고    scopus 로고
    • Increased airway smooth muscle in preschool wheezers who have asthma at school age
    • O'Reilly R, et al. (2013) Increased airway smooth muscle in preschool wheezers who have asthma at school age. J Allergy Clin Immunol 131(4):1024-1032, 1032.e1-16.
    • (2013) J Allergy Clin Immunol , vol.131 , Issue.4
    • O'Reilly, R.1
  • 14
    • 84922595423 scopus 로고    scopus 로고
    • Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling
    • Noble PB, et al. (2014) Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling. Pulm Pharmacol Ther 29(2):96-107.
    • (2014) Pulm Pharmacol Ther , vol.29 , Issue.2 , pp. 96-107
    • Noble, P.B.1
  • 15
    • 84914170420 scopus 로고    scopus 로고
    • TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis
    • Beppu LY, et al. (2014) TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis. J Allergy Clin Immunol 134(5):1100-1107.e4.
    • (2014) J Allergy Clin Immunol , vol.134 , Issue.5 , pp. 1100-1107.e4
    • Beppu, L.Y.1
  • 16
    • 29944436527 scopus 로고    scopus 로고
    • Leukotriene C4 induces TGF-beta1 production in airway epithelium via p38 kinase pathway
    • Perng DW, et al. (2006) Leukotriene C4 induces TGF-beta1 production in airway epithelium via p38 kinase pathway. Am J Respir Cell Mol Biol 34(1):101-107.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , Issue.1 , pp. 101-107
    • Perng, D.W.1
  • 17
  • 18
    • 84899741687 scopus 로고    scopus 로고
    • MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis
    • Das S, et al. (2014) MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis. Am J Respir Cell Mol Biol 50(5):882-892.
    • (2014) Am J Respir Cell Mol Biol , vol.50 , Issue.5 , pp. 882-892
    • Das, S.1
  • 19
    • 0031280307 scopus 로고    scopus 로고
    • Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by alveolar macrophages of asthmatics
    • Mautino G, Oliver N, Chanez P, Bousquet J, Capony F (1997) Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by alveolar macrophages of asthmatics. Am J Respir Cell Mol Biol 17(5):583-591.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , Issue.5 , pp. 583-591
    • Mautino, G.1    Oliver, N.2    Chanez, P.3    Bousquet, J.4    Capony, F.5
  • 20
    • 0036469065 scopus 로고    scopus 로고
    • Signal transduction and the control of gene expression
    • Brivanlou AH, Darnell JE, Jr (2002) Signal transduction and the control of gene expression. Science 295(5556):813-818.
    • (2002) Science , vol.295 , Issue.5556 , pp. 813-818
    • Brivanlou, A.H.1    Darnell, J.E.2
  • 21
    • 84923276179 scopus 로고    scopus 로고
    • RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease
    • Xiong HY, et al. (2015) RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. Science 347(6218):1254806.
    • (2015) Science , vol.347 , Issue.6218
    • Xiong, H.Y.1
  • 23
    • 34447560054 scopus 로고    scopus 로고
    • Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4
    • Jame AJ, et al. (2007) Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4. Clin Exp Allergy 37(6):880-892.
    • (2007) Clin Exp Allergy , vol.37 , Issue.6 , pp. 880-892
    • Jame, A.J.1
  • 24
    • 0035523289 scopus 로고    scopus 로고
    • Role of chemokines in the pathogenesis of asthma
    • Lukacs NW (2001) Role of chemokines in the pathogenesis of asthma. Nat Rev Immunol 1(2):108-116.
    • (2001) Nat Rev Immunol , vol.1 , Issue.2 , pp. 108-116
    • Lukacs, N.W.1
  • 25
    • 84904670489 scopus 로고    scopus 로고
    • CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations
    • Rohde G, et al. (2014) CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations. Clin Exp Allergy 44(7):930-939.
    • (2014) Clin Exp Allergy , vol.44 , Issue.7 , pp. 930-939
    • Rohde, G.1
  • 26
    • 84862626656 scopus 로고    scopus 로고
    • CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity
    • Burkhardt AM, et al. (2012) CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity. J Immunol 188(12):6399-6406.
    • (2012) J Immunol , vol.188 , Issue.12 , pp. 6399-6406
    • Burkhardt, A.M.1
  • 27
    • 84912032596 scopus 로고    scopus 로고
    • Epithelial function and dysfunction in asthma
    • Loxham M, Davies DE, Blume C (2014) Epithelial function and dysfunction in asthma. Clin Exp Allergy 44(11):1299-1313.
    • (2014) Clin Exp Allergy , vol.44 , Issue.11 , pp. 1299-1313
    • Loxham, M.1    Davies, D.E.2    Blume, C.3
  • 28
    • 44449150336 scopus 로고    scopus 로고
    • ORMDL3 gene is associated with asthma in three ethnically diverse populations
    • Galanter J, et al. (2008) ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med 177(11):1194-1200.
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.11 , pp. 1194-1200
    • Galanter, J.1
  • 29
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • Moffatt MF, et al.; GABRIEL Consortium (2010) A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 363(13):1211-1221.
    • (2010) N Engl J Med , vol.363 , Issue.13 , pp. 1211-1221
    • Moffatt, M.F.1
  • 30
    • 84943537300 scopus 로고    scopus 로고
    • Fstl1 promotes asthmatic airway remodeling by inducing oncostatin M
    • Miller M, et al. (2015) Fstl1 promotes asthmatic airway remodeling by inducing oncostatin M. J Immunol 195(8):3546-3556.
    • (2015) J Immunol , vol.195 , Issue.8 , pp. 3546-3556
    • Miller, M.1
  • 31
    • 84961233541 scopus 로고    scopus 로고
    • Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma
    • Miller M, et al. (2016) Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma. J Allergy Clin Immunol 138(2):596-599.e4.
    • (2016) J Allergy Clin Immunol , vol.138 , Issue.2 , pp. 596-599.e4
    • Miller, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.