The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome

Cell Host and Microbe

Volumn 20, Issue 3, 2016, Pages 296-306

  Chung, Lawton K ^a   Park, Yong Hwan ^b   Zheng, Yueting ^a   Brodsky, Igor E ^c   Hearing, Patrick ^a   Kastner, Daniel L ^b   Chae, Jae Jin ^b   Bliska, James B ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; PHOSPHOTRANSFERASE; PRK1 PROTEIN; PRK2 PROTEIN; PYRIN INFLAMMASOME; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; YERSINIA OUTER PROTEIN E; YOPM PROTEIN; YOPT PROTEIN; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; MEFV PROTEIN, MOUSE; OUTER MEMBRANE PROTEIN; PROTEIN KINASE C; PROTEIN KINASE N; PYRIN; YOPE PROTEIN, YERSINIA; YOPM PROTEIN, YERSINIA; YOPT PROTEIN, YERSINIA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; EFFECTOR CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TYPE III SECRETION SYSTEM; YERSINIA; YERSINIA PESTIS; YERSINIA PSEUDOTUBERCULOSIS; YOPM GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; IMMUNE EVASION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; SURVIVAL ANALYSIS; VIRULENCE; YERSINIA PSEUDOTUBERCULOSIS INFECTION;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; CYSTEINE ENDOPEPTIDASES; HOST-PATHOGEN INTERACTIONS; IMMUNE EVASION; INFLAMMASOMES; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRIN; RHOA GTP-BINDING PROTEIN; SURVIVAL ANALYSIS; VIRULENCE; VIRULENCE FACTORS; YERSINIA PSEUDOTUBERCULOSIS; YERSINIA PSEUDOTUBERCULOSIS INFECTIONS;

EID: 84995580482     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.07.018     Document Type: Article

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