메뉴 건너뛰기




Volumn 29, Issue 1, 2017, Pages

Green Toxicology: a strategy for sustainable chemical and material development

Author keywords

Alternative animal testing; Green Chemistry; Green Toxicology; In vitro assays; Predictive toxicology; Toxicogenomics

Indexed keywords

ANIMALIA;

EID: 85016942637     PISSN: 21904707     EISSN: 21904715     Source Type: Journal    
DOI: 10.1186/s12302-017-0115-z     Document Type: Editorial
Times cited : (84)

References (116)
  • 2
    • 84875144947 scopus 로고    scopus 로고
    • Green Chemistry: principles and practice
    • COI: 1:CAS:528:DC%2BD1MXhsFGrsrvK
    • Anastas P, Eghbali N (2010) Green Chemistry: principles and practice. Chem Soc Rev 39:301–312
    • (2010) Chem Soc Rev , vol.39 , pp. 301-312
    • Anastas, P.1    Eghbali, N.2
  • 4
    • 84901590344 scopus 로고    scopus 로고
    • The 24 principles of Green Engineering and Green Chemistry: “IMPROVEMENTS PRODUCTIVELY
    • COI: 1:CAS:528:DC%2BD1cXislSmsb8%3D
    • Tang SY, Bourne RA, Smith RL, Poliakoff M (2008) The 24 principles of Green Engineering and Green Chemistry: “IMPROVEMENTS PRODUCTIVELY”. Green Chem 10:268–269
    • (2008) Green Chem , vol.10 , pp. 268-269
    • Tang, S.Y.1    Bourne, R.A.2    Smith, R.L.3    Poliakoff, M.4
  • 5
    • 0028899290 scopus 로고
    • Environmentally compatible synthesis of catechol from d-glucose
    • COI: 1:CAS:528:DyaK2MXjvFOks7c%3D
    • Draths K, Frost J (1995) Environmentally compatible synthesis of catechol from d-glucose. J Am Chem Soc 117:2395–2400
    • (1995) J Am Chem Soc , vol.117 , pp. 2395-2400
    • Draths, K.1    Frost, J.2
  • 6
    • 0344609866 scopus 로고    scopus 로고
    • Shikimic acid and quinic acid: replacing isolation from plant sources with recombinant microbial biocatalysis
    • COI: 1:CAS:528:DyaK1MXot1Wltw%3D%3D
    • Draths K, Knop DR, Frost J (1999) Shikimic acid and quinic acid: replacing isolation from plant sources with recombinant microbial biocatalysis. J Am Chem Soc 121:1603–1604
    • (1999) J Am Chem Soc , vol.121 , pp. 1603-1604
    • Draths, K.1    Knop, D.R.2    Frost, J.3
  • 7
    • 0034692368 scopus 로고    scopus 로고
    • Synthesis of gallic acid and pyrogallol from glucose: replacing natural product isolation with microbial catalysis
    • COI: 1:CAS:528:DC%2BD3cXmtVOlu7g%3D
    • Kambourakis S, Draths K, Frost J (2000) Synthesis of gallic acid and pyrogallol from glucose: replacing natural product isolation with microbial catalysis. J Am Chem Soc 122:9042–9043
    • (2000) J Am Chem Soc , vol.122 , pp. 9042-9043
    • Kambourakis, S.1    Draths, K.2    Frost, J.3
  • 8
    • 84858138980 scopus 로고    scopus 로고
    • ®: biodegradable, performance-enabling plastics
    • Rieger B, Künkel A, Coates GW, Reichardt R, Dinjus E, Zevaco TA, (eds), Springer, Berlin
    • ®: biodegradable, performance-enabling plastics. In: Rieger B, Künkel A, Coates GW, Reichardt R, Dinjus E, Zevaco TA (eds) Synthetic biodegradable polymers. Springer, Berlin, pp 91–136
    • (2011) Synthetic biodegradable polymers , pp. 91-136
    • Siegenthaler, K.1    Künkel, A.2    Skupin, G.3    Yamamoto, M.4
  • 11
    • 85016927991 scopus 로고    scopus 로고
    • US EPA (2016)2011 designing greener chemicals award: the Sherwin–Williams Company—water-based acrylic alkyd technology
    • US EPA (2016) Presidential green chemistry challenge: 2011 designing greener chemicals award: the Sherwin–Williams Company—water-based acrylic alkyd technology. https://www.epa.gov/greenchemistry/presidential-green-chemistry-challenge-2011-designing-greener-chemicals-award
    • (2016) Presidential green chemistry challenge
  • 12
    • 0036736355 scopus 로고    scopus 로고
    • Origins, current status, and future challenges of Green Chemistry
    • COI: 1:CAS:528:DC%2BD38XksFOrtLs%3D
    • Anastas PT, Kirchhoff MM (2002) Origins, current status, and future challenges of Green Chemistry. Acc Chem Res 35:686–694
    • (2002) Acc Chem Res , vol.35 , pp. 686-694
    • Anastas, P.T.1    Kirchhoff, M.M.2
  • 14
    • 33847747125 scopus 로고    scopus 로고
    • Perspective on solvent use in the pharmaceutical industry
    • COI: 1:CAS:528:DC%2BD28XhtlansbjP
    • Constable DJ, Jimenez-Gonzalez C, Henderson RK (2007) Perspective on solvent use in the pharmaceutical industry. Org Process Res Dev 11:133–137
    • (2007) Org Process Res Dev , vol.11 , pp. 133-137
    • Constable, D.J.1    Jimenez-Gonzalez, C.2    Henderson, R.K.3
  • 16
  • 20
    • 85016945734 scopus 로고    scopus 로고
    • Cutting costs in chemicals management: how OECD helps governments and industry
    • OECD (2010) Cutting costs in chemicals management: how OECD helps governments and industry. Organisation for Economic Co-operation and Development, pp 1–48
    • (2010) Organisation for Economic Co-operation and Development , pp. 1-48
  • 21
    • 67650445156 scopus 로고    scopus 로고
    • Toxicology for the twenty-first century
    • COI: 1:CAS:528:DC%2BD1MXotlSgtbg%3D
    • Hartung T (2009) Toxicology for the twenty-first century. Nature 460:208–212
    • (2009) Nature , vol.460 , pp. 208-212
    • Hartung, T.1
  • 22
    • 85016965656 scopus 로고    scopus 로고
    • U.S. EPA (2016)(ToxCast™) data
    • U.S. EPA (2016) Toxicity ForeCaster (ToxCast™) data. https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data
    • (2016) Toxicity ForeCaster
  • 23
    • 80155175001 scopus 로고    scopus 로고
    • Green Chemistry and Green Engineering: a framework for sustainable technology development
    • Mulvihill MJ, Beach ES, Zimmerman JB, Anastas PT (2011) Green Chemistry and Green Engineering: a framework for sustainable technology development. Annu Rev Environ Resour 36:271–293
    • (2011) Annu Rev Environ Resour , vol.36 , pp. 271-293
    • Mulvihill, M.J.1    Beach, E.S.2    Zimmerman, J.B.3    Anastas, P.T.4
  • 24
    • 79951619024 scopus 로고    scopus 로고
    • U.S. EPA (2016)(ECOSAR) predictive model
    • U.S. EPA (2016) ecological structure activity relationships (ECOSAR) predictive model. https://www.epa.gov/tsca-screening-tools/ecological-structure-activity-relationships-ecosar-predictive-model
    • (2016) Ecological structure activity relationships
  • 25
    • 84925189481 scopus 로고    scopus 로고
    • U.S. EPA (2016)
    • U.S. EPA (2016) Toxicity Estimation Software Tool (TEST). https://www.epa.gov/chemical-research/toxicity-estimation-software-tool-test
    • (2016) Toxicity Estimation Software Tool (TEST)
  • 26
    • 73949095137 scopus 로고    scopus 로고
    • Food for thought… on in silico methods in toxicology
    • Hartung T, Hoffmann S (2009) Food for thought… on in silico methods in toxicology. Altex 26:155–166
    • (2009) Altex , vol.26 , pp. 155-166
    • Hartung, T.1    Hoffmann, S.2
  • 27
    • 69349104947 scopus 로고    scopus 로고
    • Chemical regulators have overreached
    • COI: 1:CAS:528:DC%2BD1MXhtVGitbfK
    • Hartung T, Rovida C (2009) Chemical regulators have overreached. Nature 460:1080–1081
    • (2009) Nature , vol.460 , pp. 1080-1081
    • Hartung, T.1    Rovida, C.2
  • 29
    • 84969904957 scopus 로고    scopus 로고
    • OECD (2016)
    • OECD (2016) The OECD QSAR toolbox. http://www.oecd.org/chemicalsafety/risk-assessment/theoecdqsartoolbox.htm
    • (2016) The OECD QSAR toolbox
  • 31
    • 84962788737 scopus 로고    scopus 로고
    • Global analysis of publicly available safety data for 9,801 substances registered under REACH from 2008 to 2014
    • Luechtefeld T, Maertens A, Russo DP, Rovida C, Zhu H, Hartung T (2016) Global analysis of publicly available safety data for 9,801 substances registered under REACH from 2008 to 2014. Altex 33:95–109
    • (2016) Altex , vol.33 , pp. 95-109
    • Luechtefeld, T.1    Maertens, A.2    Russo, D.P.3    Rovida, C.4    Zhu, H.5    Hartung, T.6
  • 32
    • 84962874749 scopus 로고    scopus 로고
    • Making big sense from big data in toxicology by read-across
    • Hartung T (2016) Making big sense from big data in toxicology by read-across. Altex 33:83–93
    • (2016) Altex , vol.33 , pp. 83-93
    • Hartung, T.1
  • 33
    • 84962786551 scopus 로고    scopus 로고
    • Analysis of public oral toxicity data from REACH registrations 2008–2014
    • Luechtefeld T, Maertens A, Russo DP, Rovida C, Zhu H, Hartung T (2016) Analysis of public oral toxicity data from REACH registrations 2008–2014. Altex 33:111–122
    • (2016) Altex , vol.33 , pp. 111-122
    • Luechtefeld, T.1    Maertens, A.2    Russo, D.P.3    Rovida, C.4    Zhu, H.5    Hartung, T.6
  • 34
    • 84962900969 scopus 로고    scopus 로고
    • Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008–2014 REACH data
    • Luechtefeld T, Maertens A, Russo DP, Rovida C, Zhu H, Hartung T (2016) Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008–2014 REACH data. Altex 33:123–134
    • (2016) Altex , vol.33 , pp. 123-134
    • Luechtefeld, T.1    Maertens, A.2    Russo, D.P.3    Rovida, C.4    Zhu, H.5    Hartung, T.6
  • 35
    • 84962821185 scopus 로고    scopus 로고
    • Analysis of publically available skin sensitization data from REACH registrations 2008–2014
    • Luechtefeld T, Maertens A, Russo DP, Rovida C, Zhu H, Hartung T (2016) Analysis of publically available skin sensitization data from REACH registrations 2008–2014. Altex 33:135–148
    • (2016) Altex , vol.33 , pp. 135-148
    • Luechtefeld, T.1    Maertens, A.2    Russo, D.P.3    Rovida, C.4    Zhu, H.5    Hartung, T.6
  • 45
    • 43549114744 scopus 로고    scopus 로고
    • Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)
    • COI: 1:CAS:528:DC%2BD1cXjvFKgt7c%3D
    • Lilienblum W, Dekant W, Foth H, Gebel T, Hengstler J, Kahl R, Kramer P, Schweinfurth H, Wollin K (2008) Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH). Arch Toxicol 82:211–236
    • (2008) Arch Toxicol , vol.82 , pp. 211-236
    • Lilienblum, W.1    Dekant, W.2    Foth, H.3    Gebel, T.4    Hengstler, J.5    Kahl, R.6    Kramer, P.7    Schweinfurth, H.8    Wollin, K.9
  • 47
    • 84890663411 scopus 로고    scopus 로고
    • Erratum to “Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies” [Regul. Toxicol. Pharmacol. (2012) 402–414]
    • Kolle SN, Sullivan KM, Mehling A, van Ravenzwaay B, Landsiedel R (2013) Erratum to “Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies” [Regul. Toxicol. Pharmacol. (2012) 402–414]. Regul Toxicol Pharmacol 65:366–378
    • (2013) Regul Toxicol Pharmacol , vol.65 , pp. 366-378
    • Kolle, S.N.1    Sullivan, K.M.2    Mehling, A.3    van Ravenzwaay, B.4    Landsiedel, R.5
  • 48
    • 85016980237 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: acute dermal irritation/corrosion
    • OECD (2015) OECD guideline for the testing of chemicals: acute dermal irritation/corrosion. Paris, France: Organisation for Economic Co-operation and Development Test No. 404, pp 1–8
    • (2015) Paris, France: Organisation for Economic Co-operation and Development Test , vol.404 , pp. 1-8
  • 49
    • 85016960252 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: in vitro skin corrosion: reconstructed human epidermis (RHE) test method
    • OECD (2016) OECD guideline for the testing of chemicals: in vitro skin corrosion: reconstructed human epidermis (RHE) test method. Paris, France: Organisation for Economic Co-operation and Development Test No. 431, pp 1–26
    • (2016) Paris, France: Organisation for Economic Co-operation and Development Test , vol.431 , pp. 1-26
  • 50
    • 85016936092 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: in vitro skin irritation: reconstructed human epidermis test method
    • OECD (2015) OECD guideline for the testing of chemicals: in vitro skin irritation: reconstructed human epidermis test method. Paris, France: Organisation for Economic Co-operation and Development Test No. 439, pp 1–21
    • (2015) Paris, France: Organisation for Economic Co-operation and Development Test , vol.439 , pp. 1-21
  • 51
    • 77957178643 scopus 로고
    • Bovine Corneal Opacity and Permeability test: an in vitro assay of ocular irritancy
    • COI: 1:CAS:528:DyaK38Xit12ks7w%3D
    • Gautheron P, Dukik M, Alix D, Sina JF (1992) Bovine Corneal Opacity and Permeability test: an in vitro assay of ocular irritancy. Toxicol Sci 18:442–449
    • (1992) Toxicol Sci , vol.18 , pp. 442-449
    • Gautheron, P.1    Dukik, M.2    Alix, D.3    Sina, J.F.4
  • 52
    • 85017027247 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: Bovine Corneal Opacity and Permeability test method for identifying i) chemicals inducing serious eye damage and ii) chemicals not requiring classification for eye irritation or serious eye damage
    • OECD (2013) OECD guideline for the testing of chemicals: Bovine Corneal Opacity and Permeability test method for identifying i chemicals inducing serious eye damage and ii chemicals not requiring classification for eye irritation or serious eye damage. Paris, France: Organisation for Economic Co-operation and Development Test No. 437, pp 1–27
    • (2013) Paris, France: Organisation for Economic Co-operation and Development Test , vol.437 , pp. 1-27
  • 53
    • 80053423127 scopus 로고    scopus 로고
    • In-house validation of the EpiOcular™ eye irritation test and its combination with the Bovine Corneal Opacity and Permeability test for the assessment of ocular irritation
    • COI: 1:CAS:528:DC%2BC3MXht1OmtrnO
    • Kolle SN, Kandárová H, Wareing B, van Ravenzwaay B, Landsiedel R (2011) In-house validation of the EpiOcular™ eye irritation test and its combination with the Bovine Corneal Opacity and Permeability test for the assessment of ocular irritation. ATLA Altern Lab Anim 39:365–387
    • (2011) ATLA Altern Lab Anim , vol.39 , pp. 365-387
    • Kolle, S.N.1    Kandárová, H.2    Wareing, B.3    van Ravenzwaay, B.4    Landsiedel, R.5
  • 54
    • 85017027247 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: isolated chicken eye test method for identifying i) chemicals inducing serious eye damage and ii) chemicals not requiring classification for eye irritation or serious eye damage
    • OECD (2013) OECD guideline for the testing of chemicals: isolated chicken eye test method for identifying i chemicals inducing serious eye damage and ii chemicals not requiring classification for eye irritation or serious eye damage. Paris, France: Organisation for Economic Co-operation and Development Test No. 438, pp 1–20
    • (2013) Paris, France: Organisation for Economic Co-operation and Development Test , vol.438 , pp. 1-20
  • 55
    • 85016928222 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: acute eye irritation/corrosion
    • OECD (2012) OECD guideline for the testing of chemicals: acute eye irritation/corrosion. Paris, France: Organisation for Economic Cooperation and Development Test No. 405, pp 1–19
    • (2012) Paris, France: Organisation for Economic Cooperation and Development Test , vol.405 , pp. 1-19
  • 56
    • 85017000639 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: reconstructed human cornea-like epithelium (RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage
    • OECD (2015) OECD guideline for the testing of chemicals: reconstructed human cornea-like epithelium (RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage. Paris, France: Organisation for Economic Co-operation and Development Test No. 492, pp 1–27
    • (2015) Paris, France: Organisation for Economic Co-operation and Development Test , vol.492 , pp. 1-27
  • 59
    • 85016955203 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: in chemico skin sensitisation: direct peptide reactivity assay (DPRA)
    • OECD (2015) OECD guideline for the testing of chemicals: in chemico skin sensitisation: direct peptide reactivity assay (DPRA). Paris, France: Organisation for Economic Co-operation and Development Test No. 422C, pp 1–19
    • (2015) Paris, France: Organisation for Economic Co-operation and Development Test , vol.422C , pp. 1-19
  • 60
    • 79952041429 scopus 로고    scopus 로고
    • The intra-and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: results of a ring-study in five laboratories
    • COI: 1:CAS:528:DC%2BC3MXjsFahsbw%3D
    • Andreas N, Caroline B, Leslie F, Frank G, Kimberly N, Allison H, Heather I, Robert L, Stefan O, Hendrik R (2011) The intra-and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: results of a ring-study in five laboratories. Toxicol In Vitro 25:733–744
    • (2011) Toxicol In Vitro , vol.25 , pp. 733-744
    • Andreas, N.1    Caroline, B.2    Leslie, F.3    Frank, G.4    Kimberly, N.5    Allison, H.6    Heather, I.7    Robert, L.8    Stefan, O.9    Hendrik, R.10
  • 61
    • 85016973438 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: in vitro skin sensitisation: ARE-Nrf2 luciferase test method
    • OECD (2015) OECD guideline for the testing of chemicals: in vitro skin sensitisation: ARE-Nrf2 luciferase test method. Paris, France: Organisation for Economic Co-operation and Development Test No. 442D, pp 1–20
    • (2015) Paris, France: Organisation for Economic Co-operation and Development Test , vol.442D , pp. 1-20
  • 63
    • 84957866468 scopus 로고    scopus 로고
    • Intra-and inter-laboratory reproducibility and accuracy of the LuSens assay: a reporter gene-cell line to detect keratinocyte activation by skin sensitizers
    • COI: 1:CAS:528:DC%2BC28XhvVOltbg%3D
    • Ramirez T, Stein N, Aumann A, Remus T, Edwards A, Norman KG, Ryan C, Bader JE, Fehr M, Burleson F (2016) Intra-and inter-laboratory reproducibility and accuracy of the LuSens assay: a reporter gene-cell line to detect keratinocyte activation by skin sensitizers. Toxicol In Vitro 32:278–286
    • (2016) Toxicol In Vitro , vol.32 , pp. 278-286
    • Ramirez, T.1    Stein, N.2    Aumann, A.3    Remus, T.4    Edwards, A.5    Norman, K.G.6    Ryan, C.7    Bader, J.E.8    Fehr, M.9    Burleson, F.10
  • 64
    • 85016986904 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: in vitro skin sensitisation Human Cell Line Activation Test (h-CLAT)
    • OECD (2016) OECD guideline for the testing of chemicals: in vitro skin sensitisation Human Cell Line Activation Test (h-CLAT). Paris, France: Organisation for Economic Co-operation and Development Test No. 422E, p 1–21
    • (2016) Paris, France: Organisation for Economic Co-operation and Development Test , vol.422E , pp. 1-21
  • 66
    • 85017005466 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: skin sensitisation local lymph node assay
    • OECD (2010) OECD guideline for the testing of chemicals: skin sensitisation local lymph node assay. Paris, France: Organisation for Economic Co-operation and Development Test No. 429, pp 1–20
    • (2010) Paris, France: Organisation for Economic Co-operation and Development Test , vol.429 , pp. 1-20
  • 67
    • 78349276123 scopus 로고    scopus 로고
    • A comparative evaluation of in vitro skin sensitisation tests: the human cell-line activation test (h-CLAT) versus the local lymph node assay (LLNA)
    • COI: 1:CAS:528:DC%2BC3cXhtF2rtLvM
    • Ashikaga T, Sakaguchi H, Sono S, Kosaka N, Ishikawa M, Nukada Y, Miyazawa M, Ito Y, Nishiyama N, Itagaki H (2010) A comparative evaluation of in vitro skin sensitisation tests: the human cell-line activation test (h-CLAT) versus the local lymph node assay (LLNA). ATLA Altern Lab Anim 38:275–284
    • (2010) ATLA Altern Lab Anim , vol.38 , pp. 275-284
    • Ashikaga, T.1    Sakaguchi, H.2    Sono, S.3    Kosaka, N.4    Ishikawa, M.5    Nukada, Y.6    Miyazawa, M.7    Ito, Y.8    Nishiyama, N.9    Itagaki, H.10
  • 68
    • 79960898664 scopus 로고    scopus 로고
    • Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data
    • COI: 1:CAS:528:DC%2BC3MXhtVSit73N
    • Schrage A, Hempel K, Schulz M, Kolle SN, van Ravenzwaay B, Landsiedel R (2011) Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data. ATLA Altern Lab Anim 39:273–295
    • (2011) ATLA Altern Lab Anim , vol.39 , pp. 273-295
    • Schrage, A.1    Hempel, K.2    Schulz, M.3    Kolle, S.N.4    van Ravenzwaay, B.5    Landsiedel, R.6
  • 69
    • 85016984263 scopus 로고    scopus 로고
    • OECD environment, health and safety publications series on testing and assessment: guidance document on standardised test guidelines for evaluating chemicals for endocrine disruption
    • OECD (2012) OECD environment, health and safety publications series on testing and assessment: guidance document on standardised test guidelines for evaluating chemicals for endocrine disruption. Paris, France: Organisation for Economic Co-operation and Development Test No. 150, pp 1–524
    • (2012) Paris, France: Organisation for Economic Co-operation and Development Test , vol.150 , pp. 1-524
  • 70
    • 84861213368 scopus 로고    scopus 로고
    • A testing strategy for the identification of mammalian, systemic endocrine disruptors with particular focus on steroids
    • COI: 1:CAS:528:DC%2BC38XnvFOnurg%3D
    • Kolle SN, Ramirez T, Kamp HG, Buesen R, Flick B, Strauss V, van Ravenzwaay B (2012) A testing strategy for the identification of mammalian, systemic endocrine disruptors with particular focus on steroids. Regul Toxicol Pharmacol 63:259–278
    • (2012) Regul Toxicol Pharmacol , vol.63 , pp. 259-278
    • Kolle, S.N.1    Ramirez, T.2    Kamp, H.G.3    Buesen, R.4    Flick, B.5    Strauss, V.6    van Ravenzwaay, B.7
  • 72
    • 84878040748 scopus 로고    scopus 로고
    • NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae
    • Hu C, Dillon J, Kearn J, Murray C, O’Connor V, Holden-Dye L, Morgan H (2013) NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae. PLoS ONE 8:e64297
    • (2013) PLoS ONE , vol.8
    • Hu, C.1    Dillon, J.2    Kearn, J.3    Murray, C.4    O’Connor, V.5    Holden-Dye, L.6    Morgan, H.7
  • 73
    • 84907014905 scopus 로고    scopus 로고
    • Using physiologically-based pharmacokinetic-guided “body-on-a-chip” systems to predict mammalian response to drug and chemical exposure
    • Sung JH, Srinivasan B, Esch MB, McLamb WT, Bernabini C, Shuler ML, Hickman JJ (2014) Using physiologically-based pharmacokinetic-guided “body-on-a-chip” systems to predict mammalian response to drug and chemical exposure. Exp Biol Med 239:1225–1239
    • (2014) Exp Biol Med , vol.239 , pp. 1225-1239
    • Sung, J.H.1    Srinivasan, B.2    Esch, M.B.3    McLamb, W.T.4    Bernabini, C.5    Shuler, M.L.6    Hickman, J.J.7
  • 76
    • 0020359811 scopus 로고
    • Use of chick embryo in screening for embryotoxicity
    • COI: 1:CAS:528:DyaL3sXislWmtw%3D%3D
    • Jelinek R (1982) Use of chick embryo in screening for embryotoxicity. Teratog Carcinog Mutagen 2:255–261
    • (1982) Teratog Carcinog Mutagen , vol.2 , pp. 255-261
    • Jelinek, R.1
  • 77
    • 79851510179 scopus 로고    scopus 로고
    • Zebrafish (Danio rerio) embryos as a model for testing proteratogens
    • COI: 1:CAS:528:DC%2BC3MXhvFCju7g%3D
    • Weigt S, Huebler N, Strecker R, Braunbeck T, Broschard TH (2011) Zebrafish (Danio rerio) embryos as a model for testing proteratogens. Toxicology 281:25–36
    • (2011) Toxicology , vol.281 , pp. 25-36
    • Weigt, S.1    Huebler, N.2    Strecker, R.3    Braunbeck, T.4    Broschard, T.H.5
  • 78
    • 85017036790 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals: fish embryo acute toxicity (FET) test
    • OECD (2013) OECD guideline for the testing of chemicals: fish embryo acute toxicity (FET) test. Paris, France: Organisation for Economic Co-operation and Development Test No. 236, pp 1–22
    • (2013) Paris, France: Organisation for Economic Co-operation and Development Test , vol.236 , pp. 1-22
  • 79
    • 0036098620 scopus 로고    scopus 로고
    • The ECVAM international validation study on in vitro embryotoxicity tests: results of the definitive phase and evaluation of prediction models
    • COI: 1:CAS:528:DC%2BD38XjvFehsb4%3D
    • Genschow E, Spielmann H, Scholz G, Seiler A, Brown N, Piersma A, Brady M, Clemann N, Huuskonen H, Paillard F (2002) The ECVAM international validation study on in vitro embryotoxicity tests: results of the definitive phase and evaluation of prediction models. ATLA Altern Lab Anim 30:151–176
    • (2002) ATLA Altern Lab Anim , vol.30 , pp. 151-176
    • Genschow, E.1    Spielmann, H.2    Scholz, G.3    Seiler, A.4    Brown, N.5    Piersma, A.6    Brady, M.7    Clemann, N.8    Huuskonen, H.9    Paillard, F.10
  • 80
    • 79959877538 scopus 로고    scopus 로고
    • The validated embryonic stem cell test to predict embryotoxicity in vitro
    • COI: 1:CAS:528:DC%2BC3MXotlCmur4%3D
    • Seiler AE, Spielmann H (2011) The validated embryonic stem cell test to predict embryotoxicity in vitro. Nat Protoc 6:961–978
    • (2011) Nat Protoc , vol.6 , pp. 961-978
    • Seiler, A.E.1    Spielmann, H.2
  • 81
    • 0030917962 scopus 로고    scopus 로고
    • The embryonic stem cell test (EST), an in vitro embryotoxicity test using two permanent mouse cell lines: 3T3 fibroblasts and embryonic stem cells
    • COI: 1:CAS:528:DyaK2sXjtFaitL8%3D
    • Spielmann H (1997) The embryonic stem cell test (EST), an in vitro embryotoxicity test using two permanent mouse cell lines: 3T3 fibroblasts and embryonic stem cells. In Vitro Toxicol 10:119–127
    • (1997) In Vitro Toxicol , vol.10 , pp. 119-127
    • Spielmann, H.1
  • 82
    • 84919905685 scopus 로고    scopus 로고
    • Use of the ES-D3 cell differentiation assay, combined with the BeWo transport model, to predict relative in vivo developmental toxicity of antifungal compounds
    • COI: 1:CAS:528:DC%2BC2cXitVygt73P
    • Li H, Rietjens IM, Louisse J, Blok M, Wang X, Snijders L, van Ravenzwaay B (2015) Use of the ES-D3 cell differentiation assay, combined with the BeWo transport model, to predict relative in vivo developmental toxicity of antifungal compounds. Toxicol In Vitro 29:320–328
    • (2015) Toxicol In Vitro , vol.29 , pp. 320-328
    • Li, H.1    Rietjens, I.M.2    Louisse, J.3    Blok, M.4    Wang, X.5    Snijders, L.6    van Ravenzwaay, B.7
  • 84
    • 79955960918 scopus 로고    scopus 로고
    • Linking energy metabolism to dysfunctions in mitochondrial respiration—a metabolomics in vitro approach
    • COI: 1:CAS:528:DC%2BC3MXmtFeisbs%3D
    • Balcke G, Kolle S, Kamp H, Bethan B, Looser R, Wagner S, Landsiedel R, van Ravenzwaay B (2011) Linking energy metabolism to dysfunctions in mitochondrial respiration—a metabolomics in vitro approach. Toxicol Lett 203:200–209
    • (2011) Toxicol Lett , vol.203 , pp. 200-209
    • Balcke, G.1    Kolle, S.2    Kamp, H.3    Bethan, B.4    Looser, R.5    Wagner, S.6    Landsiedel, R.7    van Ravenzwaay, B.8
  • 85
    • 81355146382 scopus 로고    scopus 로고
    • From 3D cell culture to organs-on-chips
    • COI: 1:CAS:528:DC%2BC3MXhsFSjurnM
    • Huh D, Hamilton GA, Ingber DE (2011) From 3D cell culture to organs-on-chips. Trends Cell Biol 21:745–754
    • (2011) Trends Cell Biol , vol.21 , pp. 745-754
    • Huh, D.1    Hamilton, G.A.2    Ingber, D.E.3
  • 86
    • 84926402109 scopus 로고    scopus 로고
    • In silico toxicology—current approaches and future perspectives to predict toxic effects with computational tools
    • Pfannkuch F, Suter-Dick L, (eds), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
    • Steger-Hartmann T (2014) In silico toxicology—current approaches and future perspectives to predict toxic effects with computational tools. In: Pfannkuch F, Suter-Dick L (eds) Predictive toxicology: from vision to reality. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, pp 13–32
    • (2014) Predictive toxicology: from vision to reality , pp. 13-32
    • Steger-Hartmann, T.1
  • 88
    • 79955143491 scopus 로고    scopus 로고
    • Incorporation of in silico biodegradability screening in early drug development—a feasible approach?
    • COI: 1:CAS:528:DC%2BC3MXkvFaisr0%3D
    • Steger-Hartmann T, Länge R, Heuck K (2011) Incorporation of in silico biodegradability screening in early drug development—a feasible approach? Environ Sci Pollut R 18:610–619
    • (2011) Environ Sci Pollut R , vol.18 , pp. 610-619
    • Steger-Hartmann, T.1    Länge, R.2    Heuck, K.3
  • 89
    • 0036027486 scopus 로고    scopus 로고
    • Investigations into the environmental fate and effects of iopromide (ultravist), a widely used iodinated X-ray contrast medium
    • COI: 1:CAS:528:DC%2BD3MXot1Kgsr8%3D
    • Steger-Hartmann T, Länge R, Schweinfurth H, Tschampel M, Rehmann I (2002) Investigations into the environmental fate and effects of iopromide (ultravist), a widely used iodinated X-ray contrast medium. Water Res 36:266–274
    • (2002) Water Res , vol.36 , pp. 266-274
    • Steger-Hartmann, T.1    Länge, R.2    Schweinfurth, H.3    Tschampel, M.4    Rehmann, I.5
  • 90
    • 0043193163 scopus 로고    scopus 로고
    • Environmental risk assessment for the widely used iodinated X-ray contrast agent iopromide (Ultravist)
    • COI: 1:CAS:528:DyaK1MXhvFKku78%3D
    • Steger-Hartmann T, Länge R, Schweinfurth H (1999) Environmental risk assessment for the widely used iodinated X-ray contrast agent iopromide (Ultravist). Ecotoxicol Environ Saf 42:274–281
    • (1999) Ecotoxicol Environ Saf , vol.42 , pp. 274-281
    • Steger-Hartmann, T.1    Länge, R.2    Schweinfurth, H.3
  • 91
    • 0002837142 scopus 로고    scopus 로고
    • Trace analysis of the antineoplastics ifosfamide and cyclophosphamide in sewage water by two-step solid-phase extraction and gas chromatography-mass spectrometry
    • COI: 1:CAS:528:DyaK28XitlChsL8%3D
    • Steger-Hartmann T, Kümmerer K, Schecker J (1996) Trace analysis of the antineoplastics ifosfamide and cyclophosphamide in sewage water by two-step solid-phase extraction and gas chromatography-mass spectrometry. J Chromatogr A 726:179–184
    • (1996) J Chromatogr A , vol.726 , pp. 179-184
    • Steger-Hartmann, T.1    Kümmerer, K.2    Schecker, J.3
  • 92
    • 0343485112 scopus 로고    scopus 로고
    • Biodegradability of antineoplastic compounds in screening tests: influence of glucosidation and of stereochemistry
    • Kümmerer K, Al-Ahmad A, Bertram B, Wießler M (2000) Biodegradability of antineoplastic compounds in screening tests: influence of glucosidation and of stereochemistry. Chemosphere 40:767–773
    • (2000) Chemosphere , vol.40 , pp. 767-773
    • Kümmerer, K.1    Al-Ahmad, A.2    Bertram, B.3    Wießler, M.4
  • 93
    • 84859728193 scopus 로고    scopus 로고
    • Glufosfamide: can we improve the process of anticancer agent development?
    • COI: 1:CAS:528:DC%2BC38Xltl2lsbw%3D
    • Lacombe D (2012) Glufosfamide: can we improve the process of anticancer agent development? Expert Opin Investig Drugs 21:749–754
    • (2012) Expert Opin Investig Drugs , vol.21 , pp. 749-754
    • Lacombe, D.1
  • 94
    • 34547466733 scopus 로고    scopus 로고
    • Sustainable from the very beginning: rational design of molecules by life cycle engineering as an important approach for green pharmacy and Green Chemistry
    • Kümmerer K (2007) Sustainable from the very beginning: rational design of molecules by life cycle engineering as an important approach for green pharmacy and Green Chemistry. Green Chem 9:899–907
    • (2007) Green Chem , vol.9 , pp. 899-907
    • Kümmerer, K.1
  • 95
    • 84964280219 scopus 로고    scopus 로고
    • Orphanet (2016). www.orpha.net
    • (2016) Orphanet
  • 96
    • 75849124774 scopus 로고    scopus 로고
    • Clinical Trials (2015). https://www.clinicaltrials.gov/
    • (2015) Clinical Trials
  • 97
    • 84877724593 scopus 로고    scopus 로고
    • Glucose conjugation for the specific targeting and treatment of cancer
    • COI: 1:CAS:528:DC%2BC3sXntV2jsrY%3D
    • Calvaresi EC, Hergenrother PJ (2013) Glucose conjugation for the specific targeting and treatment of cancer. Chem Sci 4:2319–2333
    • (2013) Chem Sci , vol.4 , pp. 2319-2333
    • Calvaresi, E.C.1    Hergenrother, P.J.2
  • 98
    • 84892455166 scopus 로고    scopus 로고
    • Nanotechnology—early lessons from early warnings
    • Gee D, Grandjean P, Hansen F, Hove S, MacGarvin M, Martin J, Nielsen G, Quist D, Stanners D, (eds), European Environment Agency, Copenhagen
    • Hansen SF, Maynard A, Baun A, Tickner JA, Bowman DM (2013) Nanotechnology—early lessons from early warnings. In: Gee D, Grandjean P, Hansen F, van den Hove S, MacGarvin M, Martin J, Nielsen G, Quist D, Stanners D (eds) Late lessons from early warnings II: science, precaution, innovation. European Environment Agency, Copenhagen, pp 530–559
    • (2013) Late lessons from early warnings II: science, precaution, innovation , pp. 530-559
    • Hansen, S.F.1    Maynard, A.2    Baun, A.3    Tickner, J.A.4    Bowman, D.M.5
  • 99
    • 84915745795 scopus 로고    scopus 로고
    • Spot the difference: engineered and natural nanoparticles in the environment—release, behavior, and fate
    • COI: 1:CAS:528:DC%2BC2cXhvVGksLzJ
    • Wagner S, Gondikas A, Neubauer E, Hofmann T, von der Kammer F (2014) Spot the difference: engineered and natural nanoparticles in the environment—release, behavior, and fate. Angew Chem Int Ed 53:12398–12419
    • (2014) Angew Chem Int Ed , vol.53 , pp. 12398-12419
    • Wagner, S.1    Gondikas, A.2    Neubauer, E.3    Hofmann, T.4    von der Kammer, F.5
  • 100
    • 85016993329 scopus 로고    scopus 로고
    • IARC monographs on the evaluation of carcinogenic risks to humans. World Health Organization, International Agency for Research on Cancer, Lyon, France Vol 93: Carbon Black
    • IARC (2010) IARC monographs on the evaluation of carcinogenic risks to humans. World Health Organization, International Agency for Research on Cancer, Lyon, France Vol 93: Carbon Black, Titanium Dioxide, and Talc, pp 1–466
    • (2010) Titanium Dioxide, and Talc , pp. 1-466
  • 103
    • 84881306178 scopus 로고    scopus 로고
    • Length-dependent pleural inflammation and parietal pleural responses after deposition of carbon nanotubes in the pulmonary airspaces of mice
    • Murphy FA, Poland CA, Duffin R, Donaldson K (2012) Length-dependent pleural inflammation and parietal pleural responses after deposition of carbon nanotubes in the pulmonary airspaces of mice. Nanotoxicology 7:1157–1167
    • (2012) Nanotoxicology , vol.7 , pp. 1157-1167
    • Murphy, F.A.1    Poland, C.A.2    Duffin, R.3    Donaldson, K.4
  • 104
    • 78349256324 scopus 로고    scopus 로고
    • Food for thought… on alternative methods for nanoparticle safety testing
    • Hartung T (2010) Food for thought… on alternative methods for nanoparticle safety testing. Altex 27:87–95
    • (2010) Altex , vol.27 , pp. 87-95
    • Hartung, T.1
  • 105
    • 84859832782 scopus 로고    scopus 로고
    • Alternative in vitro assays in nanomaterial toxicology
    • COI: 1:CAS:528:DC%2BC3MXhtlyrsrnN
    • Hartung T, Sabbioni E (2011) Alternative in vitro assays in nanomaterial toxicology. Wiley Interdiscip Rev Nanomed Nanobiotechnol 3:545–573
    • (2011) Wiley Interdiscip Rev Nanomed Nanobiotechnol , vol.3 , pp. 545-573
    • Hartung, T.1    Sabbioni, E.2
  • 106
    • 85017008168 scopus 로고    scopus 로고
    • Read-Across Assessment Framework (RAAF). European Chemicals Agency: Helsinki
    • ECHA (2015) Read-Across Assessment Framework (RAAF). European Chemicals Agency: Helsinki, Finland ECHA-15-R-07-EN:1–38
    • (2015) Finland ECHA-15-R-07-EN , pp. 1-38
  • 107
    • 85016960755 scopus 로고    scopus 로고
    • Guidance on grouping of chemicals, second edition; series on testing and assessment. Environment Directorate,Paris, France Test No. 194
    • OECD (2014) Guidance on grouping of chemicals, second edition; series on testing and assessment. Environment Directorate, Organisation for Economic Co-operation and Development (OECD); Paris, France Test No. 194, pp 1–141
    • (2014) Organisation for Economic Co-operation and Development (OECD)
  • 110
    • 84906101149 scopus 로고    scopus 로고
    • A strategy for grouping of nanomaterials based on key physico-chemical descriptors as a basis for safer-by-design NMs
    • COI: 1:CAS:528:DC%2BC2cXhtFWnsLvI
    • Lynch I, Weiss C, Valsami-Jones E (2014) A strategy for grouping of nanomaterials based on key physico-chemical descriptors as a basis for safer-by-design NMs. Nano Today 9:266–270
    • (2014) Nano Today , vol.9 , pp. 266-270
    • Lynch, I.1    Weiss, C.2    Valsami-Jones, E.3
  • 111
    • 84930946895 scopus 로고    scopus 로고
    • Sameness: the regulatory crux with nanomaterial identity and grouping schemes for hazard assessment
    • COI: 1:CAS:528:DC%2BC2MXhtVegs77K
    • Walser T, Studer C (2015) Sameness: the regulatory crux with nanomaterial identity and grouping schemes for hazard assessment. Regul Toxicol Pharmacol 72:569–571
    • (2015) Regul Toxicol Pharmacol , vol.72 , pp. 569-571
    • Walser, T.1    Studer, C.2
  • 114
    • 85007504704 scopus 로고    scopus 로고
    • Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation
    • Hiraku Y, Guo F, Ma N, Yamada T, Wang S, Kawanishi S, Murata M (2016) Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation. Part Fibre Toxicol 13:1–21
    • (2016) Part Fibre Toxicol , vol.13 , pp. 1-21
    • Hiraku, Y.1    Guo, F.2    Ma, N.3    Yamada, T.4    Wang, S.5    Kawanishi, S.6    Murata, M.7
  • 115
    • 84862197399 scopus 로고    scopus 로고
    • Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
    • Stern ST, Adiseshaiah PP, Crist RM (2012) Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity. Part Fibre Toxicol 9:1–15
    • (2012) Part Fibre Toxicol , vol.9 , pp. 1-15
    • Stern, S.T.1    Adiseshaiah, P.P.2    Crist, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.