Incorporation of in silico biodegradability screening in early drug development-a feasible approach?

Environmental Science and Pollution Research

Volumn 18, Issue 4, 2011, Pages 610-619

  Steger Hartmann, Thomas ^a   Länge, Reinhard ^a   Heuck, Klaus ^b  

^a Toxicology   (Germany)

^b BayerHealthcare   (Germany)

Author keywords

Biodegradability; Green chemistry; Pharmaceuticals

Indexed keywords

DRUG;

BIODEGRADATION; DRUG DEVELOPMENT; ESTIMATION METHOD; EXPERIMENTAL STUDY; FEASIBILITY STUDY; METABOLISM; PHARMACEUTICAL INDUSTRY; SENSITIVITY ANALYSIS; SILICON;

ARTICLE; BIOREMEDIATION; CHEMICAL MODEL; COMPUTER SIMULATION; DRUG SCREENING; FEASIBILITY STUDY; GREEN CHEMISTRY; METABOLISM; METHODOLOGY;

BIODEGRADATION, ENVIRONMENTAL; COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; FEASIBILITY STUDIES; GREEN CHEMISTRY TECHNOLOGY; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS;

EID: 79955143491     PISSN: 09441344     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11356-010-0403-2     Document Type: Article

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