Adverse outcome pathway (AOP) development I: Strategies and principles

Toxicological Sciences

Volumn 142, Issue 2, 2014, Pages 312-320

  Villeneuve, Daniel L ^a   Crump, Doug ^b   Garcia Reyero, Natàlia ^c   Hecker, Markus ^d   Hutchinson, Thomas H ^e   LaLone, Carlie A ^a,f   Landesmann, Brigitte ^g   Lettieri, Teresa ^g   Munn, Sharon ^g   Nepelska, Malgorzata ^g   Ottinger, Mary Ann ^h   Vergauwen, Lucia ⁱ   Whelan, Maurice ^g  

^a US EPA Mid Continent Ecology Division   (United States)

^b ENVIRONMENT CANADA   (Canada)

^c MISSISSIPPI STATE UNIVERSITY   (United States)

^d University of Saskatchewan   (Canada)

^e UNIVERSITY OF PLYMOUTH   (United Kingdom)

^f UNIVERSITY OF MINNESOTA   (United States)

^g JOINT RESEARCH CENTRE   (Italy)

^h University of Houston   (United States)

ⁱ UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Adverse outcome pathway; Extrapolation; Knowledgebase; Predictive toxicology; Regulatory toxicology

Indexed keywords

ADVERSE OUTCOME; ADVERSE OUTCOME PATHWAY; ARTICLE; CHEMICAL STRUCTURE; CONCEPTUAL FRAMEWORK; DECISION MAKING; DECISION SUPPORT SYSTEM; HUMAN; MOLECULAR INITIATING EVENT; MOLECULAR INTERACTION; PRACTICE GUIDELINE; RISK ASSESSMENT; TOXICOLOGY; ANIMAL; BIOLOGICAL MODEL; FACTUAL DATABASE; MEDICAL RESEARCH; PROCEDURES;

ANIMALS; BIOMEDICAL RESEARCH; DATABASES, FACTUAL; HUMANS; MODELS, BIOLOGICAL; TOXICOLOGY;

EID: 84921451260     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu199     Document Type: Article

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