Refinement and reduction of acute oral toxicity testing: A critical review of the use of cytotoxicity data

Alternatives to Laboratory Animals

Volumn 39, Issue 3, 2011, Pages 273-295

  Schrage, Arnhild ^a   Hempel, Katja ^a   Schulz, Markus ^a   Kolle, Susanne N ^a   Van Ravenzwaay, Bennard ^a   Landsiedel, Robert ^a  

^a BASF SE   (Germany)

Author keywords

Acute oral systemic toxicity; Balb c 3T3 fibroblasts; Cytotoxicity; In vitro; In vivo; Neutral red uptake; Three Rs

Indexed keywords

AGRICULTURAL CHEMICAL; NEUTRAL RED; TOXIC SUBSTANCE;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TESTING REFINEMENT; ARTICLE; CYTOTOXICITY TEST; FIBROBLAST; IN VITRO STUDY; IN VIVO STUDY; LD 50; MOUTH; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; TOXICITY TESTING;

ANIMALIA; RATTUS;

EID: 79960898664     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119291103900311     Document Type: Article

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