Linking energy metabolism to dysfunctions in mitochondrial respiration - A metabolomics in vitro approach

Toxicology Letters

Volumn 203, Issue 3, 2011, Pages 200-209

  Balcke, G U ^a   Kolle, S N ^b   Kamp, H ^b   Bethan, B ^a   Looser, R ^a   Wagner, S ^a   Landsiedel, Robert ^b   van Ravenzwaay, B ^b  

^a Metanomics GmbH   (Germany)

^b BASF SE   (Germany)

Author keywords

Cytochrome oxidase; Energy metabolism; In vitro metabolomics; Oxidative phosphorylation; Principle component analysis; Uncoupling

Indexed keywords

CITRIC ACID; GLYCEROPHOSPHATE; PURINE NUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXYLATION; CELL METABOLISM; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON TRANSPORT; ENERGY METABOLISM; FIBROBLAST; IN VITRO STUDY; MASS SPECTROMETRY; METABOLITE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; MULTIVARIATE ANALYSIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

2,4-DINITROPHENOL; ANIMALS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELLS, CULTURED; CRICETINAE; CRICETULUS; ELECTRON TRANSPORT; ENERGY METABOLISM; METABOLOMICS; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; POTASSIUM CYANIDE; SODIUM AZIDE;

MAMMALIA;

EID: 79955960918     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.03.013     Document Type: Article

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