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Volumn 7, Issue , 2017, Pages 124-136

Stress & the gut-brain axis: Regulation by the microbiome

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; OXYTOCIN; PREBIOTIC AGENT; PROBIOTIC AGENT; SEROTONIN; VASOPRESSIN;

EID: 85016199463     PISSN: None     EISSN: 23522895     Source Type: Journal    
DOI: 10.1016/j.ynstr.2017.03.001     Document Type: Review
Times cited : (751)

References (179)
  • 3
    • 84945289175 scopus 로고    scopus 로고
    • Use of germ-free animal models in microbiota-related research
    • Al-Asmakh, M., Zadjali, F., Use of germ-free animal models in microbiota-related research. J. Microbiol. Biotechnol. 25 (2015), 1583–1588.
    • (2015) J. Microbiol. Biotechnol. , vol.25 , pp. 1583-1588
    • Al-Asmakh, M.1    Zadjali, F.2
  • 6
    • 84909589058 scopus 로고    scopus 로고
    • The intestinal microbiota and allergic asthma
    • Arrieta, M.C., Finlay, B., The intestinal microbiota and allergic asthma. J. Infect. 69:Suppl. 1 (2014), S53–S55.
    • (2014) J. Infect. , vol.69 , pp. S53-S55
    • Arrieta, M.C.1    Finlay, B.2
  • 9
    • 84908571725 scopus 로고    scopus 로고
    • Influence of stressor-induced nervous system activation on the intestinal microbiota and the importance for immunomodulation
    • Bailey, M.T., Influence of stressor-induced nervous system activation on the intestinal microbiota and the importance for immunomodulation. Adv. Exp. Med. Biol. 817 (2014), 255–276.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 255-276
    • Bailey, M.T.1
  • 10
    • 0033191047 scopus 로고    scopus 로고
    • Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys
    • Bailey, M.T., Coe, C.L., Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Dev. Psychobiol. 35 (1999), 146–155.
    • (1999) Dev. Psychobiol. , vol.35 , pp. 146-155
    • Bailey, M.T.1    Coe, C.L.2
  • 11
    • 79551681952 scopus 로고    scopus 로고
    • Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation
    • Bailey, M.T., Dowd, S.E., Galley, J.D., Hufnagle, A.R., Allen, R.G., Lyte, M., Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain, Behav. Immun. 25 (2011), 397–407.
    • (2011) Brain, Behav. Immun. , vol.25 , pp. 397-407
    • Bailey, M.T.1    Dowd, S.E.2    Galley, J.D.3    Hufnagle, A.R.4    Allen, R.G.5    Lyte, M.6
  • 12
    • 84864002975 scopus 로고    scopus 로고
    • gamma-Aminobutyric acid production by culturable bacteria from the human intestine
    • Barrett, E., Ross, R.P., O'Toole, P.W., Fitzgerald, G.F., Stanton, C., gamma-Aminobutyric acid production by culturable bacteria from the human intestine. J. Appl. Microbiol. 113 (2012), 411–417.
    • (2012) J. Appl. Microbiol. , vol.113 , pp. 411-417
    • Barrett, E.1    Ross, R.P.2    O'Toole, P.W.3    Fitzgerald, G.F.4    Stanton, C.5
  • 13
    • 0024319605 scopus 로고
    • The immune-hypothalamic-pituitary-adrenal axis
    • Bateman, A., Singh, A., Kral, T., Solomon, S., The immune-hypothalamic-pituitary-adrenal axis. Endocr. Rev. 10 (1989), 92–112.
    • (1989) Endocr. Rev. , vol.10 , pp. 92-112
    • Bateman, A.1    Singh, A.2    Kral, T.3    Solomon, S.4
  • 14
    • 84873745317 scopus 로고    scopus 로고
    • Gut microbiota, immune development and function
    • Bengmark, S., Gut microbiota, immune development and function. Pharmacol. Res. 69 (2013), 87–113.
    • (2013) Pharmacol. Res. , vol.69 , pp. 87-113
    • Bengmark, S.1
  • 15
    • 33847666432 scopus 로고    scopus 로고
    • Impact of consuming a milk drink containing a probiotic on mood and cognition
    • Benton, D., Williams, C., Brown, A., Impact of consuming a milk drink containing a probiotic on mood and cognition. Eur. J. Clin. Nutr. 61 (2007), 355–361.
    • (2007) Eur. J. Clin. Nutr. , vol.61 , pp. 355-361
    • Benton, D.1    Williams, C.2    Brown, A.3
  • 19
    • 85008675464 scopus 로고    scopus 로고
    • Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress
    • Bharwani, A., Mian, M.F., Surette, M.G., Bienenstock, J., Forsythe, P., Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress. BMC Med., 15, 2017, 7.
    • (2017) BMC Med. , vol.15 , pp. 7
    • Bharwani, A.1    Mian, M.F.2    Surette, M.G.3    Bienenstock, J.4    Forsythe, P.5
  • 21
    • 84868212781 scopus 로고    scopus 로고
    • The immune system and developmental programming of brain and behavior
    • Bilbo, S.D., Schwarz, J.M., The immune system and developmental programming of brain and behavior. Front. Neuroendocrinol. 33 (2012), 267–286.
    • (2012) Front. Neuroendocrinol. , vol.33 , pp. 267-286
    • Bilbo, S.D.1    Schwarz, J.M.2
  • 23
    • 84940662313 scopus 로고    scopus 로고
    • Host biology in light of the microbiome: ten principles of holobionts and hologenomes
    • e1002226
    • Bordenstein, S.R., Theis, K.R., Host biology in light of the microbiome: ten principles of holobionts and hologenomes. PLoS Biol., 13, 2015 e1002226.
    • (2015) PLoS Biol. , vol.13
    • Bordenstein, S.R.1    Theis, K.R.2
  • 27
    • 85013756511 scopus 로고    scopus 로고
    • Targeting the microbiota-gut-brain Axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice
    • Burokas, A., Arboleya, S., Moloney, R.D., Peterson, V.L., Murphy, K., Clarke, G., Stanton, C., Dinan, T.G., Cryan, J.F., Targeting the microbiota-gut-brain Axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice. Biol. Psychiatry, 2017 http://dx.doi.org/10.1016/j.biopsych.2016.12.031.
    • (2017) Biol. Psychiatry
    • Burokas, A.1    Arboleya, S.2    Moloney, R.D.3    Peterson, V.L.4    Murphy, K.5    Clarke, G.6    Stanton, C.7    Dinan, T.G.8    Cryan, J.F.9
  • 28
    • 84975678760 scopus 로고    scopus 로고
    • How gut microbes talk to organs: the role of endocrine and nervous routes
    • Cani, P.D., Knauf, C., How gut microbes talk to organs: the role of endocrine and nervous routes. Mol. Metab. 5 (2016), 743–752.
    • (2016) Mol. Metab. , vol.5 , pp. 743-752
    • Cani, P.D.1    Knauf, C.2
  • 29
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani, P.D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A.M., Delzenne, N.M., Burcelin, R., Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57 (2008), 1470–1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6    Burcelin, R.7
  • 30
    • 84888201085 scopus 로고    scopus 로고
    • Gut microbiota, enteroendocrine functions and metabolism
    • Cani, P.D., Everard, A., Duparc, T., Gut microbiota, enteroendocrine functions and metabolism. Curr. Opin. Pharmacol. 13 (2013), 935–940.
    • (2013) Curr. Opin. Pharmacol. , vol.13 , pp. 935-940
    • Cani, P.D.1    Everard, A.2    Duparc, T.3
  • 31
    • 84926315282 scopus 로고    scopus 로고
    • The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems
    • Carabotti, M., Scirocco, A., Maselli, M.A., Severi, C., The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann. Gastroenterol. 28 (2015), 203–209.
    • (2015) Ann. Gastroenterol. , vol.28 , pp. 203-209
    • Carabotti, M.1    Scirocco, A.2    Maselli, M.A.3    Severi, C.4
  • 32
    • 84856033373 scopus 로고    scopus 로고
    • Review article: probiotics for the treatment of irritable bowel syndrome–focus on lactic acid bacteria
    • Clarke, G., Cryan, J.F., Dinan, T.G., Quigley, E.M., Review article: probiotics for the treatment of irritable bowel syndrome–focus on lactic acid bacteria. Alimentary Pharmacol. Ther. 35 (2012), 403–413.
    • (2012) Alimentary Pharmacol. Ther. , vol.35 , pp. 403-413
    • Clarke, G.1    Cryan, J.F.2    Dinan, T.G.3    Quigley, E.M.4
  • 33
    • 84878241830 scopus 로고    scopus 로고
    • The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
    • Clarke, G., Grenham, S., Scully, P., Fitzgerald, P., Moloney, R.D., Shanahan, F., Dinan, T.G., Cryan, J.F., The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol. Psychiatr. 18 (2013), 666–673.
    • (2013) Mol. Psychiatr. , vol.18 , pp. 666-673
    • Clarke, G.1    Grenham, S.2    Scully, P.3    Fitzgerald, P.4    Moloney, R.D.5    Shanahan, F.6    Dinan, T.G.7    Cryan, J.F.8
  • 34
    • 85046982618 scopus 로고    scopus 로고
    • Microbial ecology and host-microbiota interactions during early life stages
    • Collado, M.C., Cernada, M., Bauerl, C., Vento, M., Perez-Martinez, G., Microbial ecology and host-microbiota interactions during early life stages. Gut Microbes 3 (2012), 352–365.
    • (2012) Gut Microbes , vol.3 , pp. 352-365
    • Collado, M.C.1    Cernada, M.2    Bauerl, C.3    Vento, M.4    Perez-Martinez, G.5
  • 35
    • 33947174847 scopus 로고    scopus 로고
    • Serotonin and its role in colonic function and in gastrointestinal disorders
    • Costedio, M.M., Hyman, N., Mawe, G.M., Serotonin and its role in colonic function and in gastrointestinal disorders. Dis. Colon Rectum 50 (2007), 376–388.
    • (2007) Dis. Colon Rectum , vol.50 , pp. 376-388
    • Costedio, M.M.1    Hyman, N.2    Mawe, G.M.3
  • 36
    • 33746120837 scopus 로고    scopus 로고
    • How do SSRIs help patients with irritable bowel syndrome?
    • Creed, F., How do SSRIs help patients with irritable bowel syndrome?. Gut 55 (2006), 1065–1067.
    • (2006) Gut , vol.55 , pp. 1065-1067
    • Creed, F.1
  • 39
    • 84866546211 scopus 로고    scopus 로고
    • Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour, Nature reviews
    • Cryan, J.F., Dinan, T.G., Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour, Nature reviews. Neuroscience 13 (2012), 701–712.
    • (2012) Neuroscience , vol.13 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 40
    • 84995468862 scopus 로고    scopus 로고
    • Sex-specific effects of docosahexaenoic acid (DHA) on the microbiome and behavior of socially-isolated mice
    • Davis, D.J., Hecht, P.M., Jasarevic, E., Beversdorf, D.Q., Will, M.J., Fritsche, K., Gillespie, C.H., Sex-specific effects of docosahexaenoic acid (DHA) on the microbiome and behavior of socially-isolated mice. Brain Behav. Immun. 59 (2017 Jan), 38–48, 10.1016/j.bbi.2016.09.003.
    • (2017) Brain Behav. Immun. , vol.59 , pp. 38-48
    • Davis, D.J.1    Hecht, P.M.2    Jasarevic, E.3    Beversdorf, D.Q.4    Will, M.J.5    Fritsche, K.6    Gillespie, C.H.7
  • 41
    • 84904337496 scopus 로고    scopus 로고
    • The microbiota-gut-brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?
    • De Palma, G., Collins, S.M., Bercik, P., Verdu, E.F., The microbiota-gut-brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?. J. Physiology 592 (2014), 2989–2997.
    • (2014) J. Physiology , vol.592 , pp. 2989-2997
    • De Palma, G.1    Collins, S.M.2    Bercik, P.3    Verdu, E.F.4
  • 43
    • 85005990865 scopus 로고    scopus 로고
    • Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice
    • de Sousa Rodrigues, M.E., Bekhbat, M., Houser, M.C., Chang, J., Walker, D.I., Jones, D.P., Oller do Nascimento, C.M., Barnum, C.J., Tansey, M.G., Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice. Brain, Behav. Immun. 59 (2017), 158–172.
    • (2017) Brain, Behav. Immun. , vol.59 , pp. 158-172
    • de Sousa Rodrigues, M.E.1    Bekhbat, M.2    Houser, M.C.3    Chang, J.4    Walker, D.I.5    Jones, D.P.6    Oller do Nascimento, C.M.7    Barnum, C.J.8    Tansey, M.G.9
  • 44
    • 53049087266 scopus 로고    scopus 로고
    • The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat
    • Desbonnet, L., Garrett, L., Clarke, G., Bienenstock, J., Dinan, T.G., The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat. J. Psychiatric Res. 43 (2008), 164–174.
    • (2008) J. Psychiatric Res. , vol.43 , pp. 164-174
    • Desbonnet, L.1    Garrett, L.2    Clarke, G.3    Bienenstock, J.4    Dinan, T.G.5
  • 45
    • 77957142793 scopus 로고    scopus 로고
    • Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression
    • Desbonnet, L., Garrett, L., Clarke, G., Kiely, B., Cryan, J.F., Dinan, T.G., Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 170 (2010), 1179–1188.
    • (2010) Neuroscience , vol.170 , pp. 1179-1188
    • Desbonnet, L.1    Garrett, L.2    Clarke, G.3    Kiely, B.4    Cryan, J.F.5    Dinan, T.G.6
  • 49
    • 84881295719 scopus 로고    scopus 로고
    • Melancholic microbes: a link between gut microbiota and depression?
    • Dinan, T.G., Cryan, J.F., Melancholic microbes: a link between gut microbiota and depression?. Neurogastroenterol. Motil. 25 (2013), 713–719.
    • (2013) Neurogastroenterol. Motil. , vol.25 , pp. 713-719
    • Dinan, T.G.1    Cryan, J.F.2
  • 50
    • 84886724158 scopus 로고    scopus 로고
    • Psychobiotics: a novel class of psychotropic
    • Dinan, T.G., Stanton, C., Cryan, J.F., Psychobiotics: a novel class of psychotropic. Biol. Psychiatry 74 (2013), 720–726.
    • (2013) Biol. Psychiatry , vol.74 , pp. 720-726
    • Dinan, T.G.1    Stanton, C.2    Cryan, J.F.3
  • 51
    • 84920563271 scopus 로고    scopus 로고
    • Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP
    • e106503
    • Distrutti, E., O'Reilly, J.A., McDonald, C., Cipriani, S., Renga, B., Lynch, M.A., Fiorucci, S., Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP. PLoS One, 9, 2014 e106503.
    • (2014) PLoS One , vol.9
    • Distrutti, E.1    O'Reilly, J.A.2    McDonald, C.3    Cipriani, S.4    Renga, B.5    Lynch, M.A.6    Fiorucci, S.7
  • 54
    • 84875238640 scopus 로고    scopus 로고
    • The microbiota and the gut-brain axis: insights from the temporal and spatial mucosal alterations during colonisation of the germfree mouse intestine
    • El Aidy, S., Kunze, W., Bienenstock, J., Kleerebezem, M., The microbiota and the gut-brain axis: insights from the temporal and spatial mucosal alterations during colonisation of the germfree mouse intestine. Benef. Microbes 3 (2012), 251–259.
    • (2012) Benef. Microbes , vol.3 , pp. 251-259
    • El Aidy, S.1    Kunze, W.2    Bienenstock, J.3    Kleerebezem, M.4
  • 55
    • 0035219190 scopus 로고    scopus 로고
    • Stress may add bite to appetite in women: a laboratory study of stress-induced cortisol and eating behavior
    • Epel, E., Lapidus, R., McEwen, B., Brownell, K., Stress may add bite to appetite in women: a laboratory study of stress-induced cortisol and eating behavior. Psychoneuroendocrinology 26 (2001), 37–49.
    • (2001) Psychoneuroendocrinology , vol.26 , pp. 37-49
    • Epel, E.1    Lapidus, R.2    McEwen, B.3    Brownell, K.4
  • 58
    • 80052259151 scopus 로고    scopus 로고
    • High-fat diet selectively protects against the effects of chronic social stress in the mouse
    • Finger, B.C., Dinan, T.G., Cryan, J.F., High-fat diet selectively protects against the effects of chronic social stress in the mouse. Neuroscience 192 (2011), 351–360.
    • (2011) Neuroscience , vol.192 , pp. 351-360
    • Finger, B.C.1    Dinan, T.G.2    Cryan, J.F.3
  • 59
    • 3142708683 scopus 로고    scopus 로고
    • The interface of psychiatry and irritable bowel syndrome
    • Folks, D.G., The interface of psychiatry and irritable bowel syndrome. Curr. Psychiatr. Rep. 6 (2004), 210–215.
    • (2004) Curr. Psychiatr. Rep. , vol.6 , pp. 210-215
    • Folks, D.G.1
  • 61
    • 84909630912 scopus 로고    scopus 로고
    • Vagal pathways for microbiome-brain-gut axis communication
    • Forsythe, P., Bienenstock, J., Kunze, W.A., Vagal pathways for microbiome-brain-gut axis communication. Adv. Exp. Med. Biol. 817 (2014), 115–133.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 115-133
    • Forsythe, P.1    Bienenstock, J.2    Kunze, W.A.3
  • 62
    • 84877145046 scopus 로고    scopus 로고
    • Gut-brain axis: how the microbiome influences anxiety and depression
    • Foster, J.A., McVey Neufeld, K.A., Gut-brain axis: how the microbiome influences anxiety and depression. Trends Neurosci. 36 (2013), 305–312.
    • (2013) Trends Neurosci. , vol.36 , pp. 305-312
    • Foster, J.A.1    McVey Neufeld, K.A.2
  • 63
    • 84861990759 scopus 로고    scopus 로고
    • Techniques used to characterize the gut microbiota: a guide for the clinician, Nature reviews
    • Fraher, M.H., O'Toole, P.W., Quigley, E.M., Techniques used to characterize the gut microbiota: a guide for the clinician, Nature reviews. Gastroenterol. Hepatol. 9 (2012), 312–322.
    • (2012) Gastroenterol. Hepatol. , vol.9 , pp. 312-322
    • Fraher, M.H.1    O'Toole, P.W.2    Quigley, E.M.3
  • 66
    • 84904084581 scopus 로고    scopus 로고
    • Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota
    • Galley, J.D., Nelson, M.C., Yu, Z., Dowd, S.E., Walter, J., Kumar, P.S., Lyte, M., Bailey, M.T., Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota. BMC Microbiol., 14, 2014, 189.
    • (2014) BMC Microbiol. , vol.14 , pp. 189
    • Galley, J.D.1    Nelson, M.C.2    Yu, Z.3    Dowd, S.E.4    Walter, J.5    Kumar, P.S.6    Lyte, M.7    Bailey, M.T.8
  • 67
    • 84909606798 scopus 로고    scopus 로고
    • Microbiota-gut-brain axis and cognitive function
    • Gareau, M.G., Microbiota-gut-brain axis and cognitive function. Adv. Exp. Med. Biol. 817 (2014), 357–371.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 357-371
    • Gareau, M.G.1
  • 68
    • 47249141324 scopus 로고    scopus 로고
    • Pathophysiological mechanisms of stress-induced intestinal damage
    • Gareau, M.G., Silva, M.A., Perdue, M.H., Pathophysiological mechanisms of stress-induced intestinal damage. Curr. Mol. Med. 8 (2008), 274–281.
    • (2008) Curr. Mol. Med. , vol.8 , pp. 274-281
    • Gareau, M.G.1    Silva, M.A.2    Perdue, M.H.3
  • 69
    • 0141612894 scopus 로고    scopus 로고
    • Interactions between the enteric nervous system and the immune system: role of neuropeptides and nutrition
    • Genton, L., Kudsk, K.A., Interactions between the enteric nervous system and the immune system: role of neuropeptides and nutrition. Am. J. Surg. 186 (2003), 253–258.
    • (2003) Am. J. Surg. , vol.186 , pp. 253-258
    • Genton, L.1    Kudsk, K.A.2
  • 70
    • 33846347644 scopus 로고    scopus 로고
    • The serotonin signaling system: from basic understanding to drug development for functional GI disorders
    • Gershon, M.D., Tack, J., The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology 132 (2007), 397–414.
    • (2007) Gastroenterology , vol.132 , pp. 397-414
    • Gershon, M.D.1    Tack, J.2
  • 71
    • 39049192179 scopus 로고    scopus 로고
    • Vagal complexity: substrate for body-mind connections?
    • Goehler, L.E., Vagal complexity: substrate for body-mind connections?. Bratisl. Lek. listy 107 (2006), 275–276.
    • (2006) Bratisl. Lek. listy , vol.107 , pp. 275-276
    • Goehler, L.E.1
  • 74
    • 84901361574 scopus 로고    scopus 로고
    • Germ-free mice as a model to study effect of gut microbiota on host physiology
    • Grover, M., Kashyap, P.C., Germ-free mice as a model to study effect of gut microbiota on host physiology. Neurogastroenterol. Motil. 26 (2014), 745–748.
    • (2014) Neurogastroenterol. Motil. , vol.26 , pp. 745-748
    • Grover, M.1    Kashyap, P.C.2
  • 76
    • 0032923998 scopus 로고    scopus 로고
    • Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression
    • Harkin, A., Kelly, J.P., McNamara, M., Connor, T.J., Dredge, K., Redmond, A., Leonard, B.E., Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression. Eur. J. Pharmacol. 364 (1999), 123–132.
    • (1999) Eur. J. Pharmacol. , vol.364 , pp. 123-132
    • Harkin, A.1    Kelly, J.P.2    McNamara, M.3    Connor, T.J.4    Dredge, K.5    Redmond, A.6    Leonard, B.E.7
  • 79
    • 84938379194 scopus 로고    scopus 로고
    • Neuropeptides and the microbiota-gut-brain axis
    • Holzer, P., Farzi, A., Neuropeptides and the microbiota-gut-brain axis. Adv. Exp. Med. Biol. 817 (2014), 195–219.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 195-219
    • Holzer, P.1    Farzi, A.2
  • 80
    • 0029554162 scopus 로고
    • The autonomic nervous system as a communication channel between the brain and the immune system
    • Hori, T., KAtafuchi, T., Take, S., Shimizu, N., Niijima, A., The autonomic nervous system as a communication channel between the brain and the immune system. Neuroimmunomodulat 2 (1995), 203–215.
    • (1995) Neuroimmunomodulat , vol.2 , pp. 203-215
    • Hori, T.1    KAtafuchi, T.2    Take, S.3    Shimizu, N.4    Niijima, A.5
  • 83
    • 84905376185 scopus 로고    scopus 로고
    • Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions
    • Hyland, N.P., Quigley, E.M., Brint, E., Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions. World J. Gastroenterol. 20 (2014), 8859–8866.
    • (2014) World J. Gastroenterol. , vol.20 , pp. 8859-8866
    • Hyland, N.P.1    Quigley, E.M.2    Brint, E.3
  • 84
    • 84923163629 scopus 로고    scopus 로고
    • From circuits to behaviour in the amygdala
    • Janak, P.H., Tye, K.M., From circuits to behaviour in the amygdala. Nature 517 (2015), 284–292.
    • (2015) Nature , vol.517 , pp. 284-292
    • Janak, P.H.1    Tye, K.M.2
  • 85
    • 84942739564 scopus 로고    scopus 로고
    • Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain
    • Jasarevic, E., Howerton, C.L., Howard, C.D., Bale, T.L., Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain. Endocrinology 156 (2015), 3265–3276.
    • (2015) Endocrinology , vol.156 , pp. 3265-3276
    • Jasarevic, E.1    Howerton, C.L.2    Howard, C.D.3    Bale, T.L.4
  • 86
    • 84861578319 scopus 로고    scopus 로고
    • An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota
    • Jeffery, I.B., O'Toole, P.W., Ohman, L., Claesson, M.J., Deane, J., Quigley, E.M., Simren, M., An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut 61 (2012), 997–1006.
    • (2012) Gut , vol.61 , pp. 997-1006
    • Jeffery, I.B.1    O'Toole, P.W.2    Ohman, L.3    Claesson, M.J.4    Deane, J.5    Quigley, E.M.6    Simren, M.7
  • 92
    • 84867616398 scopus 로고    scopus 로고
    • High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
    • e47713
    • Kim, K.A., Gu, W., Lee, I.A., Joh, E.H., Kim, D.H., High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway. PLoS One, 7, 2012 e47713.
    • (2012) PLoS One , vol.7
    • Kim, K.A.1    Gu, W.2    Lee, I.A.3    Joh, E.H.4    Kim, D.H.5
  • 93
    • 70350573103 scopus 로고    scopus 로고
    • Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening
    • Kunze, W.A., Mao, Y.K., Wang, B., Huizinga, J.D., Ma, X., Forsythe, P., Bienenstock, J., Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening. J. Cell. Mol. Med. 13 (2009), 2261–2270.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 2261-2270
    • Kunze, W.A.1    Mao, Y.K.2    Wang, B.3    Huizinga, J.D.4    Ma, X.5    Forsythe, P.6    Bienenstock, J.7
  • 94
    • 84924594557 scopus 로고    scopus 로고
    • The gut microbiota in internal medicine: implications for health and disease
    • Lankelma, J.M., Nieuwdorp, M., de Vos, W.M., Wiersinga, W.J., The gut microbiota in internal medicine: implications for health and disease. Neth. J. Med. 73 (2015), 61–68.
    • (2015) Neth. J. Med. , vol.73 , pp. 61-68
    • Lankelma, J.M.1    Nieuwdorp, M.2    de Vos, W.M.3    Wiersinga, W.J.4
  • 95
    • 84856190424 scopus 로고    scopus 로고
    • Stress and visceral pain: from animal models to clinical therapies
    • Larauche, M., Mulak, A., Tache, Y., Stress and visceral pain: from animal models to clinical therapies. Exp. Neurol. 233 (2012), 49–67.
    • (2012) Exp. Neurol. , vol.233 , pp. 49-67
    • Larauche, M.1    Mulak, A.2    Tache, Y.3
  • 96
    • 35348858152 scopus 로고    scopus 로고
    • The amygdala
    • LeDoux, J., The amygdala. Curr. Biol. CB 17 (2007), R868–R874.
    • (2007) Curr. Biol. CB , vol.17 , pp. R868-R874
    • LeDoux, J.1
  • 97
    • 34548086786 scopus 로고    scopus 로고
    • HPA and immune axes in stress: involvement of the serotonergic system
    • Leonard, B.E., HPA and immune axes in stress: involvement of the serotonergic system. Neuroimmunomodulat 13 (2006), 268–276.
    • (2006) Neuroimmunomodulat , vol.13 , pp. 268-276
    • Leonard, B.E.1
  • 98
    • 84944050761 scopus 로고    scopus 로고
    • Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress
    • Liang, S., Wang, T., Hu, X., Luo, J., Li, W., Wu, X., Duan, Y., Jin, F., Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress. Neuroscience 310 (2015), 561–577.
    • (2015) Neuroscience , vol.310 , pp. 561-577
    • Liang, S.1    Wang, T.2    Hu, X.3    Luo, J.4    Li, W.5    Wu, X.6    Duan, Y.7    Jin, F.8
  • 99
    • 84947774477 scopus 로고    scopus 로고
    • Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice
    • Liu, W.H., Chuang, H.L., Huang, Y.T., Wu, C.C., Chou, G.T., Wang, S., Tsai, Y.C., Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice. Behav. Brain Res. 298 (2016), 202–209.
    • (2016) Behav. Brain Res. , vol.298 , pp. 202-209
    • Liu, W.H.1    Chuang, H.L.2    Huang, Y.T.3    Wu, C.C.4    Chou, G.T.5    Wang, S.6    Tsai, Y.C.7
  • 100
    • 84956891227 scopus 로고    scopus 로고
    • Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naive adult mice
    • Liu, Y.W., Liu, W.H., Wu, C.C., Juan, Y.C., Wu, Y.C., Tsai, H.P., Wang, S., Tsai, Y.C., Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naive adult mice. Brain Res. 1631 (2016), 1–12.
    • (2016) Brain Res. , vol.1631 , pp. 1-12
    • Liu, Y.W.1    Liu, W.H.2    Wu, C.C.3    Juan, Y.C.4    Wu, Y.C.5    Tsai, H.P.6    Wang, S.7    Tsai, Y.C.8
  • 101
    • 84942518278 scopus 로고    scopus 로고
    • Revisiting the mechanisms of CNS immune privilege
    • Louveau, A., Harris, T.H., Kipnis, J., Revisiting the mechanisms of CNS immune privilege. Trends Immunol. 36 (2015), 569–577.
    • (2015) Trends Immunol. , vol.36 , pp. 569-577
    • Louveau, A.1    Harris, T.H.2    Kipnis, J.3
  • 103
    • 84978215414 scopus 로고    scopus 로고
    • Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus
    • Luczynski, P., Whelan, S.O., O'Sullivan, C., Clarke, G., Shanahan, F., Dinan, T.G., Cryan, J.F., Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus. Eur. J. Neurosci. 44 (2016), 2654–2666.
    • (2016) Eur. J. Neurosci. , vol.44 , pp. 2654-2666
    • Luczynski, P.1    Whelan, S.O.2    O'Sullivan, C.3    Clarke, G.4    Shanahan, F.5    Dinan, T.G.6    Cryan, J.F.7
  • 104
    • 84911485386 scopus 로고    scopus 로고
    • Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression
    • Luna, R.A., Foster, J.A., Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression. Curr. Opin. Biotechnol. 32 (2015), 35–41.
    • (2015) Curr. Opin. Biotechnol. , vol.32 , pp. 35-41
    • Luna, R.A.1    Foster, J.A.2
  • 105
    • 47249097557 scopus 로고    scopus 로고
    • The role of microbiota and probiotics in stress-induced gastro-intestinal damage
    • Lutgendorff, F., Akkermans, L.M., Soderholm, J.D., The role of microbiota and probiotics in stress-induced gastro-intestinal damage. Curr. Mol. Med. 8 (2008), 282–298.
    • (2008) Curr. Mol. Med. , vol.8 , pp. 282-298
    • Lutgendorff, F.1    Akkermans, L.M.2    Soderholm, J.D.3
  • 106
    • 0032144624 scopus 로고    scopus 로고
    • Anxiogenic effect of subclinical bacterial infection in mice in the absence of overt immune activation
    • Lyte, M., Varcoe, J.J., Bailey, M.T., Anxiogenic effect of subclinical bacterial infection in mice in the absence of overt immune activation. Physiol. Behav. 65 (1998), 63–68.
    • (1998) Physiol. Behav. , vol.65 , pp. 63-68
    • Lyte, M.1    Varcoe, J.J.2    Bailey, M.T.3
  • 107
    • 0036964196 scopus 로고    scopus 로고
    • Gut flora–mechanisms of regulation
    • Macpherson, A.J., Uhr, T., Gut flora–mechanisms of regulation. Eur. J. Surg.(Suppl. l), 2002, 53–57.
    • (2002) Eur. J. Surg. , pp. 53-57
    • Macpherson, A.J.1    Uhr, T.2
  • 108
    • 59849104578 scopus 로고    scopus 로고
    • Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria
    • Maes, M., Leunis, J.C., Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria. Neuro Endocrinol. Lett. 29 (2008), 902–910.
    • (2008) Neuro Endocrinol. Lett. , vol.29 , pp. 902-910
    • Maes, M.1    Leunis, J.C.2
  • 109
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression
    • Maes, M., Yirmyia, R., Noraberg, J., Brene, S., Hibbeln, J., Perini, G., Kubera, M., Bob, P., Lerer, B., Maj, M., The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression. Metab. Brain Dis. 24 (2009), 27–53.
    • (2009) Metab. Brain Dis. , vol.24 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3    Brene, S.4    Hibbeln, J.5    Perini, G.6    Kubera, M.7    Bob, P.8    Lerer, B.9    Maj, M.10
  • 110
    • 84875300745 scopus 로고    scopus 로고
    • In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes
    • Maes, M., Kubera, M., Leunis, J.C., Berk, M., Geffard, M., Bosmans, E., In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes. Acta Psychiatr. Scand. 127 (2013), 344–354.
    • (2013) Acta Psychiatr. Scand. , vol.127 , pp. 344-354
    • Maes, M.1    Kubera, M.2    Leunis, J.C.3    Berk, M.4    Geffard, M.5    Bosmans, E.6
  • 113
    • 84898777631 scopus 로고    scopus 로고
    • Brain-gut microbiome interactions and functional bowel disorders
    • Mayer, E.A., Savidge, T., Shulman, R.J., Brain-gut microbiome interactions and functional bowel disorders. Gastroenterology 146 (2014), 1500–1512.
    • (2014) Gastroenterology , vol.146 , pp. 1500-1512
    • Mayer, E.A.1    Savidge, T.2    Shulman, R.J.3
  • 116
    • 33845786505 scopus 로고    scopus 로고
    • 5-HT in the enteric nervous system: gut function and neuropharmacology
    • McLean, P.G., Borman, R.A., Lee, K., 5-HT in the enteric nervous system: gut function and neuropharmacology. Trends Neurosci. 30 (2007), 9–13.
    • (2007) Trends Neurosci. , vol.30 , pp. 9-13
    • McLean, P.G.1    Borman, R.A.2    Lee, K.3
  • 117
    • 84872686051 scopus 로고    scopus 로고
    • The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse
    • McVey Neufeld, K.A., Mao, Y.K., Bienenstock, J., Foster, J.A., Kunze, W.A., The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse. Neurogastroenterol. Motil. 25 (2013), 183–e188.
    • (2013) Neurogastroenterol. Motil. , vol.25 , pp. 183-e188
    • McVey Neufeld, K.A.1    Mao, Y.K.2    Bienenstock, J.3    Foster, J.A.4    Kunze, W.A.5
  • 118
    • 0038726073 scopus 로고    scopus 로고
    • Overview of functional gastrointestinal disorders: dysfunction of the brain-gut axis
    • (v)
    • Mertz, H.R., Overview of functional gastrointestinal disorders: dysfunction of the brain-gut axis. Gastroenterology Clin. N. Am. 32 (2003), 463–476 (v).
    • (2003) Gastroenterology Clin. N. Am. , vol.32 , pp. 463-476
    • Mertz, H.R.1
  • 119
    • 79953160733 scopus 로고    scopus 로고
    • Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects
    • Messaoudi, M., Lalonde, R., Violle, N., Javelot, H., Desor, D., Nejdi, A., Bisson, J.F., Rougeot, C., Pichelin, M., Cazaubiel, M., Cazaubiel, J.M., Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br. J. Nutr. 105 (2011), 755–764.
    • (2011) Br. J. Nutr. , vol.105 , pp. 755-764
    • Messaoudi, M.1    Lalonde, R.2    Violle, N.3    Javelot, H.4    Desor, D.5    Nejdi, A.6    Bisson, J.F.7    Rougeot, C.8    Pichelin, M.9    Cazaubiel, M.10    Cazaubiel, J.M.11
  • 120
    • 85046980563 scopus 로고    scopus 로고
    • Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers
    • Messaoudi, M., Violle, N., Bisson, J.F., Desor, D., Javelot, H., Rougeot, C., Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes 2 (2011), 256–261.
    • (2011) Gut Microbes , vol.2 , pp. 256-261
    • Messaoudi, M.1    Violle, N.2    Bisson, J.F.3    Desor, D.4    Javelot, H.5    Rougeot, C.6
  • 122
    • 84926670347 scopus 로고    scopus 로고
    • Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities
    • Moloney, R.D., O'Mahony, S.M., Dinan, T.G., Cryan, J.F., Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities. Front. Psychiatr., 6, 2015, 15.
    • (2015) Front. Psychiatr. , vol.6 , pp. 15
    • Moloney, R.D.1    O'Mahony, S.M.2    Dinan, T.G.3    Cryan, J.F.4
  • 125
    • 85010461784 scopus 로고    scopus 로고
    • Chronic early-life stress in rat pups alters basal corticosterone, intestinal permeability, and fecal microbiota at weaning: influence of sex
    • Moussaoui, N., Jacobs, J.P., Larauche, M., Biraud, M., Million, M., Mayer, E., Tache, Y., Chronic early-life stress in rat pups alters basal corticosterone, intestinal permeability, and fecal microbiota at weaning: influence of sex. J. Neurogastroenterol. Motil. 23:1 (2017 Jan 30), 135–143.
    • (2017) J. Neurogastroenterol. Motil. , vol.23 , Issue.1 , pp. 135-143
    • Moussaoui, N.1    Jacobs, J.P.2    Larauche, M.3    Biraud, M.4    Million, M.5    Mayer, E.6    Tache, Y.7
  • 127
    • 84996555017 scopus 로고    scopus 로고
    • Comparison of faecal microbiota in Blastocystis-positive and Blastocystis-negative irritable bowel syndrome patients
    • Nagel, R., Traub, R.J., Allcock, R.J., Kwan, M.M., Bielefeldt-Ohmann, H., Comparison of faecal microbiota in Blastocystis-positive and Blastocystis-negative irritable bowel syndrome patients. Microbiome, 4, 2016, 47.
    • (2016) Microbiome , vol.4 , pp. 47
    • Nagel, R.1    Traub, R.J.2    Allcock, R.J.3    Kwan, M.M.4    Bielefeldt-Ohmann, H.5
  • 128
    • 34347258134 scopus 로고    scopus 로고
    • Autonomic innervation and regulation of the immune system (1987-2007)
    • Nance, D.M., Sanders, V.M., Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav. Immun. 21 (2007), 736–745.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 736-745
    • Nance, D.M.1    Sanders, V.M.2
  • 130
    • 0023883691 scopus 로고
    • Colorectal distension as a noxious visceral stimulus - physiologic and pharmacologic characterization of pseudaffective reflexes in the rat
    • Ness, T.J., Gebhart, G.F., Colorectal distension as a noxious visceral stimulus - physiologic and pharmacologic characterization of pseudaffective reflexes in the rat. Brain Res. 450 (1988), 153–169.
    • (1988) Brain Res. , vol.450 , pp. 153-169
    • Ness, T.J.1    Gebhart, G.F.2
  • 131
    • 79551713705 scopus 로고    scopus 로고
    • Reduced anxiety-like behavior and central neurochemical change in germ-free mice
    • e119
    • Neufeld, K.M., Kang, N., Bienenstock, J., Foster, J.A., Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterol. Motil. 23 (2011), 255–264 e119.
    • (2011) Neurogastroenterol. Motil. , vol.23 , pp. 255-264
    • Neufeld, K.M.1    Kang, N.2    Bienenstock, J.3    Foster, J.A.4
  • 132
    • 84920404296 scopus 로고    scopus 로고
    • How informative is the mouse for human gut microbiota research?
    • Nguyen, T.L., Vieira-Silva, S., Liston, A., Raes, J., How informative is the mouse for human gut microbiota research?. Dis. Models Mech. 8 (2015), 1–16.
    • (2015) Dis. Models Mech. , vol.8 , pp. 1-16
    • Nguyen, T.L.1    Vieira-Silva, S.2    Liston, A.3    Raes, J.4
  • 133
    • 84912531587 scopus 로고    scopus 로고
    • A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis
    • O'Leary, O.F., Cryan, J.F., A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis. Trends Pharmacol. Sci. 35 (2014), 675–687.
    • (2014) Trends Pharmacol. Sci. , vol.35 , pp. 675-687
    • O'Leary, O.F.1    Cryan, J.F.2
  • 134
    • 58149291318 scopus 로고    scopus 로고
    • Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses
    • O'Mahony, S.M., Marchesi, J.R., Scully, P., Codling, C., Ceolho, A.M., Quigley, E.M., Cryan, J.F., Dinan, T.G., Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol. Psych. 65 (2009), 263–267.
    • (2009) Biol. Psych. , vol.65 , pp. 263-267
    • O'Mahony, S.M.1    Marchesi, J.R.2    Scully, P.3    Codling, C.4    Ceolho, A.M.5    Quigley, E.M.6    Cryan, J.F.7    Dinan, T.G.8
  • 135
  • 140
    • 84903750783 scopus 로고    scopus 로고
    • The gut-brain axis rewired: adding a functional vagal nicotinic “sensory synapse”
    • Perez-Burgos, A., Mao, Y.K., Bienenstock, J., Kunze, W.A., The gut-brain axis rewired: adding a functional vagal nicotinic “sensory synapse”. FASEB J. 28 (2014), 3064–3074.
    • (2014) FASEB J. , vol.28 , pp. 3064-3074
    • Perez-Burgos, A.1    Mao, Y.K.2    Bienenstock, J.3    Kunze, W.A.4
  • 142
    • 78049396557 scopus 로고
    • The treatment of melancholia by the lactic acid Bacillus
    • Philips, J.P.G., The treatment of melancholia by the lactic acid Bacillus. Br. J. Psychiatr. 56 (1910), 422–431.
    • (1910) Br. J. Psychiatr. , vol.56 , pp. 422-431
    • Philips, J.P.G.1
  • 146
    • 80054857288 scopus 로고    scopus 로고
    • Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    • Rajilic-Stojanovic, M., Biagi, E., Heilig, H.G., Kajander, K., Kekkonen, R.A., Tims, S., de Vos, W.M., Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology 141 (2011), 1792–1801.
    • (2011) Gastroenterology , vol.141 , pp. 1792-1801
    • Rajilic-Stojanovic, M.1    Biagi, E.2    Heilig, H.G.3    Kajander, K.4    Kekkonen, R.A.5    Tims, S.6    de Vos, W.M.7
  • 148
    • 72449188746 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome
    • Rao, A.V., Bested, A.C., Beaulne, T.M., Katzman, M.A., Iorio, C., Berardi, J.M., Logan, A.C., A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome. Gut Pathog., 1, 2009, 6.
    • (2009) Gut Pathog. , vol.1 , pp. 6
    • Rao, A.V.1    Bested, A.C.2    Beaulne, T.M.3    Katzman, M.A.4    Iorio, C.5    Berardi, J.M.6    Logan, A.C.7
  • 149
    • 67650333217 scopus 로고    scopus 로고
    • Principles and clinical implications of the brain-gut-enteric microbiota axis, Nature reviews
    • Rhee, S.H., Pothoulakis, C., Mayer, E.A., Principles and clinical implications of the brain-gut-enteric microbiota axis, Nature reviews. Gastroenterol. Hepatol. 6 (2009), 306–314.
    • (2009) Gastroenterol. Hepatol. , vol.6 , pp. 306-314
    • Rhee, S.H.1    Pothoulakis, C.2    Mayer, E.A.3
  • 150
    • 84929310699 scopus 로고    scopus 로고
    • Control of brain development, function, and behavior by the microbiome
    • Sampson, T.R., Mazmanian, S.K., Control of brain development, function, and behavior by the microbiome. Cell Host Microbe 17 (2015), 565–576.
    • (2015) Cell Host Microbe , vol.17 , pp. 565-576
    • Sampson, T.R.1    Mazmanian, S.K.2
  • 152
    • 84887130474 scopus 로고    scopus 로고
    • Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine
    • Savignac, H.M., Corona, G., Mills, H., Chen, L., Spencer, J.P., Tzortzis, G., Burnet, P.W., Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine. Neurochem. Int. 63 (2013), 756–764.
    • (2013) Neurochem. Int. , vol.63 , pp. 756-764
    • Savignac, H.M.1    Corona, G.2    Mills, H.3    Chen, L.4    Spencer, J.P.5    Tzortzis, G.6    Burnet, P.W.7
  • 153
    • 84907873992 scopus 로고    scopus 로고
    • Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice
    • Savignac, H.M., Kiely, B., Dinan, T.G., Cryan, J.F., Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice. Neurogastroenterol. Motil. 26 (2014), 1615–1627.
    • (2014) Neurogastroenterol. Motil. , vol.26 , pp. 1615-1627
    • Savignac, H.M.1    Kiely, B.2    Dinan, T.G.3    Cryan, J.F.4
  • 156
    • 84937636483 scopus 로고    scopus 로고
    • Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers
    • Schmidt, K., Cowen, P.J., Harmer, C.J., Tzortzis, G., Errington, S., Burnet, P.W., Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Psychopharmacology 232 (2015), 1793–1801.
    • (2015) Psychopharmacology , vol.232 , pp. 1793-1801
    • Schmidt, K.1    Cowen, P.J.2    Harmer, C.J.3    Tzortzis, G.4    Errington, S.5    Burnet, P.W.6
  • 157
    • 33747064990 scopus 로고    scopus 로고
    • Stereological analysis of amygdala neuron number in autism
    • Schumann, C.M., Amaral, D.G., Stereological analysis of amygdala neuron number in autism. J. Neurosci. 26 (2006), 7674–7679.
    • (2006) J. Neurosci. , vol.26 , pp. 7674-7679
    • Schumann, C.M.1    Amaral, D.G.2
  • 158
    • 84961288867 scopus 로고    scopus 로고
    • Are we really vastly Outnumbered? Revisiting the ratio of bacterial to host cells in humans
    • Sender, R., Fuchs, S., Milo, R., Are we really vastly Outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 164 (2016), 337–340.
    • (2016) Cell , vol.164 , pp. 337-340
    • Sender, R.1    Fuchs, S.2    Milo, R.3
  • 159
    • 84875219963 scopus 로고    scopus 로고
    • Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry
    • Sharma, S., Fulton, S., Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry. Int. J. Obes. 37 (2013), 382–389.
    • (2013) Int. J. Obes. , vol.37 , pp. 382-389
    • Sharma, S.1    Fulton, S.2
  • 160
    • 84978863659 scopus 로고    scopus 로고
    • May the force Be with you: the light and dark sides of the microbiota-gut-brain Axis in neuropsychiatry
    • Sherwin, E., Sandhu, K.V., Dinan, T.G., Cryan, J.F., May the force Be with you: the light and dark sides of the microbiota-gut-brain Axis in neuropsychiatry. CNS drugs 30 (2016), 1019–1041.
    • (2016) CNS drugs , vol.30 , pp. 1019-1041
    • Sherwin, E.1    Sandhu, K.V.2    Dinan, T.G.3    Cryan, J.F.4
  • 161
    • 84933678330 scopus 로고    scopus 로고
    • Microbiota, the immune system, black moods and the brain-melancholia updated
    • Smythies, L.E., Smythies, J.R., Microbiota, the immune system, black moods and the brain-melancholia updated. Front. Hum. Neurosci., 8, 2014, 720.
    • (2014) Front. Hum. Neurosci. , vol.8 , pp. 720
    • Smythies, L.E.1    Smythies, J.R.2
  • 162
    • 84929369869 scopus 로고    scopus 로고
    • A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood
    • Steenbergen, L., Sellaro, R., van Hemert, S., Bosch, J.A., Colzato, L.S., A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain, Behav. Immun. 48 (2015), 258–264.
    • (2015) Brain, Behav. Immun. , vol.48 , pp. 258-264
    • Steenbergen, L.1    Sellaro, R.2    van Hemert, S.3    Bosch, J.A.4    Colzato, L.S.5
  • 163
    • 84891628557 scopus 로고    scopus 로고
    • Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis
    • Stilling, R.M., Dinan, T.G., Cryan, J.F., Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis. Genes, Brain, Behav. 13 (2014), 69–86.
    • (2014) Genes, Brain, Behav. , vol.13 , pp. 69-86
    • Stilling, R.M.1    Dinan, T.G.2    Cryan, J.F.3
  • 164
    • 84938150375 scopus 로고    scopus 로고
    • Microbes & neurodevelopment–Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala
    • Stilling, R.M., Ryan, F.J., Hoban, A.E., Shanahan, F., Clarke, G., Claesson, M.J., Dinan, T.G., Cryan, J.F., Microbes & neurodevelopment–Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala. Brain, Behav. Immun. 50 (2015), 209–220.
    • (2015) Brain, Behav. Immun. , vol.50 , pp. 209-220
    • Stilling, R.M.1    Ryan, F.J.2    Hoban, A.E.3    Shanahan, F.4    Clarke, G.5    Claesson, M.J.6    Dinan, T.G.7    Cryan, J.F.8
  • 165
    • 4043161248 scopus 로고    scopus 로고
    • Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice
    • Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X.N., Kubo, C., Koga, Y., Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J. Physiol. 558 (2004), 263–275.
    • (2004) J. Physiol. , vol.558 , pp. 263-275
    • Sudo, N.1    Chida, Y.2    Aiba, Y.3    Sonoda, J.4    Oyama, N.5    Yu, X.N.6    Kubo, C.7    Koga, Y.8
  • 166
    • 84955579153 scopus 로고    scopus 로고
    • High-fat-diet-induced obesity is associated with decreased antiinflammatory Lactobacillus reuteri sensitive to oxidative stress in mouse Peyer's patches
    • Sun, J., Qiao, Y., Qi, C., Jiang, W., Xiao, H., Shi, Y., Le, G.W., High-fat-diet-induced obesity is associated with decreased antiinflammatory Lactobacillus reuteri sensitive to oxidative stress in mouse Peyer's patches. Nutrition 32 (2016), 265–272.
    • (2016) Nutrition , vol.32 , pp. 265-272
    • Sun, J.1    Qiao, Y.2    Qi, C.3    Jiang, W.4    Xiao, H.5    Shi, Y.6    Le, G.W.7
  • 167
    • 84936803964 scopus 로고    scopus 로고
    • The prebiotics 3'Sialyllactose and 6'Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut-brain axis
    • Tarr, A.J., Galley, J.D., Fisher, S.E., Chichlowski, M., Berg, B.M., Bailey, M.T., The prebiotics 3'Sialyllactose and 6'Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut-brain axis. Brain, Behav. Immun. 50 (2015), 166–177.
    • (2015) Brain, Behav. Immun. , vol.50 , pp. 166-177
    • Tarr, A.J.1    Galley, J.D.2    Fisher, S.E.3    Chichlowski, M.4    Berg, B.M.5    Bailey, M.T.6
  • 168
    • 85012088520 scopus 로고    scopus 로고
    • Dietary prebiotics and bioactive milk fractions improve NREM sleep, enhance REM sleep rebound and attenuate the stress-induced decrease in Diurnal temperature and gut microbial alpha diversity
    • Thompson, R.S., Roller, R., Mika, A., Greenwood, B.N., Knight, R., Chichlowski, M., Berg, B.M., Fleshner, M., Dietary prebiotics and bioactive milk fractions improve NREM sleep, enhance REM sleep rebound and attenuate the stress-induced decrease in Diurnal temperature and gut microbial alpha diversity. Front. Behav. Neurosci., 10, 2016, 240.
    • (2016) Front. Behav. Neurosci. , vol.10 , pp. 240
    • Thompson, R.S.1    Roller, R.2    Mika, A.3    Greenwood, B.N.4    Knight, R.5    Chichlowski, M.6    Berg, B.M.7    Fleshner, M.8
  • 173
    • 84944413352 scopus 로고    scopus 로고
    • Lactobacillus fermentum NS9 restores the antibiotic induced physiological and psychological abnormalities in rats
    • Wang, T., Hu, X., Liang, S., Li, W., Wu, X., Wang, L., Jin, F., Lactobacillus fermentum NS9 restores the antibiotic induced physiological and psychological abnormalities in rats. Benef. Microbes 6 (2015), 707–717.
    • (2015) Benef. Microbes , vol.6 , pp. 707-717
    • Wang, T.1    Hu, X.2    Liang, S.3    Li, W.4    Wu, X.5    Wang, L.6    Jin, F.7
  • 174
    • 84931261861 scopus 로고    scopus 로고
    • Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene
    • Wei, Y., Melas, P.A., Wegener, G., Mathe, A.A., Lavebratt, C., Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. Int. J. Neuropsychopharmacol., 18, 2014.
    • (2014) Int. J. Neuropsychopharmacol. , vol.18
    • Wei, Y.1    Melas, P.A.2    Wegener, G.3    Mathe, A.A.4    Lavebratt, C.5
  • 175
    • 84937126408 scopus 로고    scopus 로고
    • Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection
    • Williamson, L.L., McKenney, E.A., Holzknecht, Z.E., Belliveau, C., Rawls, J.F., Poulton, S., Parker, W., Bilbo, S.D., Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection. Brain, Behav. Immun. 51 (2016), 14–28.
    • (2016) Brain, Behav. Immun. , vol.51 , pp. 14-28
    • Williamson, L.L.1    McKenney, E.A.2    Holzknecht, Z.E.3    Belliveau, C.4    Rawls, J.F.5    Poulton, S.6    Parker, W.7    Bilbo, S.D.8
  • 178
    • 84877052713 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonist spironolactone prevents chronic corticosterone induced depression-like behavior
    • Wu, T.C., Chen, H.T., Chang, H.Y., Yang, C.Y., Hsiao, M.C., Cheng, M.L., Chen, J.C., Mineralocorticoid receptor antagonist spironolactone prevents chronic corticosterone induced depression-like behavior. Psychoneuroendocrinology 38 (2013), 871–883.
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 871-883
    • Wu, T.C.1    Chen, H.T.2    Chang, H.Y.3    Yang, C.Y.4    Hsiao, M.C.5    Cheng, M.L.6    Chen, J.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.