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Volumn 7, Issue 10, 2012, Pages

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 1; CYCLOOXYGENASE 2; CYTOKINE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; OCCLUDIN; PROTEIN KINASE B; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FKHRL1;

EID: 84867616398     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047713     Document Type: Article
Times cited : (928)

References (34)
  • 2
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • Wellen KE, Hotamisligil GS, (2005) Inflammation, stress, and diabetes. J Clin Invest 115: 1111-1119.
    • (2005) J Clin Invest , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 3
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS, (2006) Inflammation and metabolic disorders. Nature 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 4
    • 85047687451 scopus 로고    scopus 로고
    • Lymphatic system: a vital link between metabolic syndrome and inflammation
    • Chakraborty S, Zawieja S, Wang W, Zawieja DC, Muthuchamy M, (2010) Lymphatic system: a vital link between metabolic syndrome and inflammation. Ann N Y Acad Sci 1207 (Suppl 1):: E94-102.
    • (2010) Ann N Y Acad Sci , vol.1207 , Issue.SUPPL. 1 , pp. 94-102
    • Chakraborty, S.1    Zawieja, S.2    Wang, W.3    Zawieja, D.C.4    Muthuchamy, M.5
  • 5
    • 77955362775 scopus 로고    scopus 로고
    • Chronic inflammation in obesity and the metabolic syndrome
    • Monteiro R, Azevedo I (2010) Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm 2010.
    • (2010) Mediators Inflamm 2010
    • Monteiro, R.1    Azevedo, I.2
  • 6
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, et al. (2008) Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57: 1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5
  • 7
    • 72249106180 scopus 로고    scopus 로고
    • Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance
    • Ghanim H, Abuaysheh S, Sia CL, Korzeniewski K, Chaudhuri A, et al. (2009) Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal: implications for insulin resistance. Diabetes Care 32: 2281-2287.
    • (2009) Diabetes Care , vol.32 , pp. 2281-2287
    • Ghanim, H.1    Abuaysheh, S.2    Sia, C.L.3    Korzeniewski, K.4    Chaudhuri, A.5
  • 8
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, et al. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112: 1796-1808.
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3    Rosenbaum, M.4    Leibel, R.L.5
  • 9
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, et al. (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116: 1494-1505.
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3    Kotani, K.4    Hiasa, K.5
  • 10
    • 70350188297 scopus 로고    scopus 로고
    • Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome
    • Maury E, Brichard SM, (2010) Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Mol Cell Endocrinol 314: 1-16.
    • (2010) Mol Cell Endocrinol , vol.314 , pp. 1-16
    • Maury, E.1    Brichard, S.M.2
  • 11
    • 33748314535 scopus 로고    scopus 로고
    • Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
    • Cancello R, Tordjman J, Poitou C, Guilhem G, Bouillot JL, et al. (2006) Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes 55: 1554-1561.
    • (2006) Diabetes , vol.55 , pp. 1554-1561
    • Cancello, R.1    Tordjman, J.2    Poitou, C.3    Guilhem, G.4    Bouillot, J.L.5
  • 12
    • 77955595990 scopus 로고    scopus 로고
    • Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation
    • de La Serre CB, Ellis CL, Lee J, Hartman AL, Rutledge JC, et al. (2010) Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation. Am J Physiol Gastrointest Liver Physiol 299: G440-448.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • de la Serre, C.B.1    Ellis, C.L.2    Lee, J.3    Hartman, A.L.4    Rutledge, J.C.5
  • 13
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5
  • 14
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed F, Ding H, Wang T, Hooper LV, Koh GY, et al. (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 101: 15718-15723.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15718-15723
    • Backhed, F.1    Ding, H.2    Wang, T.3    Hooper, L.V.4    Koh, G.Y.5
  • 16
    • 77957880664 scopus 로고    scopus 로고
    • High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse
    • Ding S, Chi MM, Scull BP, Rigby R, Schwerbrock NM, et al. (2010) High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. PLoS One 5: e12191.
    • (2010) PLoS One , vol.5
    • Ding, S.1    Chi, M.M.2    Scull, B.P.3    Rigby, R.4    Schwerbrock, N.M.5
  • 17
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI, (2006) Microbial ecology: human gut microbes associated with obesity. Nature 444: 1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 19
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • Turnbaugh PJ, Backhed F, Fulton L, Gordon JI, (2008) Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3: 213-223.
    • (2008) Cell Host Microbe , vol.3 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 20
    • 17644405863 scopus 로고    scopus 로고
    • Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease
    • Hollenbach E, Vieth M, Roessner A, Neumann M, Malfertheiner P, et al. (2005) Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease. J Biol Chem 280: 14981-14988.
    • (2005) J Biol Chem , vol.280 , pp. 14981-14988
    • Hollenbach, E.1    Vieth, M.2    Roessner, A.3    Neumann, M.4    Malfertheiner, P.5
  • 21
    • 79953054617 scopus 로고    scopus 로고
    • Kalopanaxsaponin A ameliorates experimental colitis in mice by inhibiting IRAK-1 activation in the NF-kappaB and MAPK pathways
    • Joh EH, Kim DH, (2011) Kalopanaxsaponin A ameliorates experimental colitis in mice by inhibiting IRAK-1 activation in the NF-kappaB and MAPK pathways. Br J Pharmacol 162: 1731-1742.
    • (2011) Br J Pharmacol , vol.162 , pp. 1731-1742
    • Joh, E.H.1    Kim, D.H.2
  • 22
    • 56149118096 scopus 로고    scopus 로고
    • Ecology of danger-dependent cytokine-boosted spontaneous abortion in the CBA x DBA/2 mouse model: II. Fecal LPS levels in colonies with different basal abortion rates
    • Clark DA, Chaouat G, Banwatt D, Friebe A, Arck PC, (2008) Ecology of danger-dependent cytokine-boosted spontaneous abortion in the CBA x DBA/2 mouse model: II. Fecal LPS levels in colonies with different basal abortion rates. Am J Reprod Immunol 60: 529-533.
    • (2008) Am J Reprod Immunol , vol.60 , pp. 529-533
    • Clark, D.A.1    Chaouat, G.2    Banwatt, D.3    Friebe, A.4    Arck, P.C.5
  • 23
    • 77950543296 scopus 로고    scopus 로고
    • The analysis of oral microbial communities of wild-type and toll-like receptor 2-deficient mice using a 454 GS FLX Titanium pyrosequencer
    • Chun J, Kim KY, Lee JH, Choi Y, (2010) The analysis of oral microbial communities of wild-type and toll-like receptor 2-deficient mice using a 454 GS FLX Titanium pyrosequencer. BMC Microbiol 10: 101.
    • (2010) BMC Microbiol , vol.10 , pp. 101
    • Chun, J.1    Kim, K.Y.2    Lee, J.H.3    Choi, Y.4
  • 24
    • 38049059990 scopus 로고    scopus 로고
    • The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction
    • Kim DH, Kim JY, Yu BP, Chung HY, (2008) The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction. Biogerontology 9: 33-47.
    • (2008) Biogerontology , vol.9 , pp. 33-47
    • Kim, D.H.1    Kim, J.Y.2    Yu, B.P.3    Chung, H.Y.4
  • 25
    • 69949111703 scopus 로고    scopus 로고
    • The core gut microbiome, energy balance and obesity
    • Turnbaugh PJ, Gordon JI, (2009) The core gut microbiome, energy balance and obesity. J Physiol 587: 4153-4158.
    • (2009) J Physiol , vol.587 , pp. 4153-4158
    • Turnbaugh, P.J.1    Gordon, J.I.2
  • 26
    • 74249119678 scopus 로고    scopus 로고
    • Obesity and the human microbiome
    • Ley RE, (2010) Obesity and the human microbiome. Curr Opin Gastroenterol 26: 5-11.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 5-11
    • Ley, R.E.1
  • 28
    • 80755185875 scopus 로고    scopus 로고
    • Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue
    • Geurts L, Lazarevic V, Derrien M, Everard A, Van Roye M, et al. (2011) Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue. Front Microbiol 2: 149.
    • (2011) Front Microbiol , vol.2 , pp. 149
    • Geurts, L.1    Lazarevic, V.2    Derrien, M.3    Everard, A.4    van Roye, M.5
  • 29
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, et al. (2007) Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56: 1761-1772.
    • (2007) Diabetes , vol.56 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3    Poggi, M.4    Knauf, C.5
  • 30
    • 55849086542 scopus 로고    scopus 로고
    • Intestinal, adipose, and liver inflammation in diet-induced obese mice
    • Li H, Lelliott C, Hakansson P, Ploj K, Tuneld A, et al. (2008) Intestinal, adipose, and liver inflammation in diet-induced obese mice. Metabolism 57: 1704-1710.
    • (2008) Metabolism , vol.57 , pp. 1704-1710
    • Li, H.1    Lelliott, C.2    Hakansson, P.3    Ploj, K.4    Tuneld, A.5
  • 31
    • 79959271480 scopus 로고    scopus 로고
    • Role of intestinal inflammation as an early event in obesity and insulin resistance
    • Ding S, Lund PK, (2011) Role of intestinal inflammation as an early event in obesity and insulin resistance. Curr Opin Clin Nutr Metab Care 14: 328-333.
    • (2011) Curr Opin Clin Nutr Metab Care , vol.14 , pp. 328-333
    • Ding, S.1    Lund, P.K.2
  • 32
    • 33947301294 scopus 로고    scopus 로고
    • Immune dysfunction in inflammatory bowel disease
    • Neuman MG, (2007) Immune dysfunction in inflammatory bowel disease. Transl Res 149: 173-186.
    • (2007) Transl Res , vol.149 , pp. 173-186
    • Neuman, M.G.1
  • 33
    • 33847040759 scopus 로고    scopus 로고
    • Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis
    • Brun P, Castagliuolo I, Di Leo V, Buda A, Pinzani M, et al. (2007) Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol 292: G518-525.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Brun, P.1    Castagliuolo, I.2    Di Leo, V.3    Buda, A.4    Pinzani, M.5
  • 34
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • Nicholson KM, Anderson NG, (2002) The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 14: 381-395.
    • (2002) Cell Signal , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.