Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Distrutti, Eleonora ^a   O'Reilly, Julie Ann ^b   McDonald, Claire ^b   Cipriani, Sabrina ^c   Renga, Barbara ^c   Lynch, Marina A ^b   Fiorucci, Stefano ^c  

^a SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; PROBIOTIC AGENT; SYNAPSIN; BIOLOGICAL MARKER; TRANSCRIPTOME;

ACTINOBACTERIA; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL STRAIN; BACTEROIDETES; BIFIDOBACTERIUM BREVE; BIFIDOBACTERIUM INFANTIS; BIFIDOBACTERIUM LONGUM; BRAIN FUNCTION; CELL ACTIVATION; COGNITION; CONTROLLED STUDY; DNA EXTRACTION; EXCITATORY POSTSYNAPTIC POTENTIAL; FECES ANALYSIS; GENE AMPLIFICATION; GENE EXPRESSION; HIPPOCAMPUS; INTESTINE FLORA; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS DELBRUECKII SUBSP. BULGARICUS; LACTOBACILLUS PARACASEI; LACTOBACILLUS PLANTARUM; LACTOBACILLUS REUTERI; LONG TERM POTENTIATION; MALE; MICROARRAY ANALYSIS; MICROGLIA; NERVE CELL PLASTICITY; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA HYBRIDIZATION; RNA ISOLATION; STREPTOCOCCUS THERMOPHILUS; WESTERN BLOTTING; ANIMAL; BRAIN; CYTOLOGY; DRUG EFFECTS; INTESTINE; METABOLISM; MICROBIOLOGY; MICROFLORA; NERVE CELL; PHYSIOLOGY; WISTAR RAT;

AGING; ANIMALS; BIOLOGICAL MARKERS; BRAIN; HIPPOCAMPUS; INTESTINES; LONG-TERM POTENTIATION; MALE; MICROBIOTA; NEURONS; PROBIOTICS; RATS; RATS, WISTAR; TRANSCRIPTOME;

EID: 84920563271     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106503     Document Type: Article

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