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Volumn 50, Issue 3, 2007, Pages 376-388

Serotonin and its role in colonic function and in gastrointestinal disorders

Author keywords

5 HT 3 and 5 HT4 receptors; Constipation; Enterochromaffin cells; Irritable bowel syndrome

Indexed keywords

4,7 DIHYDRO 7 OXO N (3 QUINUCLIDINYL)THIENO[3,2 B]PYRIDINE 6 CARBOXAMIDE; ALOSETRON; CHOLINESTERASE INHIBITOR; CILANSETRON; CISAPRIDE; DOLASETRON MESILATE; GRANISETRON; MOSAPRIDE CITRATE; NEOSTIGMINE; ONDANSETRON; PALONOSETRON; PIBOSEROD; PROKINETIC AGENT; PRUCALOPRIDE; RAMOSETRON; RENZAPRIDE; SEROTONIN; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN 4 AGONIST; SEROTONIN 4 ANTAGONIST; SEROTONIN 4 RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; TEGASEROD; UNCLASSIFIED DRUG;

EID: 33947174847     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/s10350-006-0763-3     Document Type: Review
Times cited : (149)

References (132)
  • 1
    • 84912634131 scopus 로고
    • The movements and innervation of the small intestine
    • WM Bayliss EH Starling 1899 The movements and innervation of the small intestine J Physiol 24 99 143
    • (1899) J Physiol , vol.24 , pp. 99-143
    • Bayliss, W.M.1    Starling, E.H.2
  • 2
    • 84944484700 scopus 로고
    • The movements and innervation of the small intestine
    • WM Bayliss EH Starling 1900 The movements and innervation of the small intestine J Physiol 26 107 138
    • (1900) J Physiol , vol.26 , pp. 107-138
    • Bayliss, W.M.1    Starling, E.H.2
  • 3
    • 0002716935 scopus 로고
    • The release of 5-hydroxytryptamine in relation to pressure exerted on the intestinal mucosa
    • E Bulbring A Crema 1959 The release of 5-hydroxytryptamine in relation to pressure exerted on the intestinal mucosa J Physiol 146 18 28
    • (1959) J Physiol , vol.146 , pp. 18-28
    • Bulbring, E.1    Crema, A.2
  • 4
    • 0009861402 scopus 로고
    • Ricerche sul secreto delle cellule enterochromaffini
    • V Erspamer M Vialli 1937 Ricerche sul secreto delle cellule enterochromaffini Boll Soc Med Chir Pavia 51 357 363
    • (1937) Boll Soc Med Chir Pavia , vol.51 , pp. 357-363
    • Erspamer, V.1    Vialli, M.2
  • 5
    • 0032861214 scopus 로고    scopus 로고
    • The discovery of serotonin and its role in neuroscience
    • PM Whitaker-Azmitia 1999 The discovery of serotonin and its role in neuroscience Neuropsychopharmacology 21 2S 8S
    • (1999) Neuropsychopharmacology , vol.21
    • Whitaker-Azmitia, P.M.1
  • 6
    • 0343165759 scopus 로고
    • The vascular action of natural serotonin, 5- and 7-hydroxytryptamine and tryptamine
    • IH Page 1952 The vascular action of natural serotonin, 5- and 7-hydroxytryptamine and tryptamine J Pharmacol Exp Ther 105 58 73
    • (1952) J Pharmacol Exp Ther , vol.105 , pp. 58-73
    • Page, I.H.1
  • 7
    • 33749796078 scopus 로고
    • Serotonin (5-hydroxytryptamine)
    • IH Page 1954 Serotonin (5-hydroxytryptamine) Physiol Rev 34 563 588
    • (1954) Physiol Rev , vol.34 , pp. 563-588
    • Page, I.H.1
  • 8
    • 0002476115 scopus 로고
    • The action of 5-hydroxytryptamine, 5-hydroxytryptophan and reserpine on intestinal peristalsis in anaesthetized guinea-pigs
    • E Bulbring A Crema 1959 The action of 5-hydroxytryptamine, 5-hydroxytryptophan and reserpine on intestinal peristalsis in anaesthetized guinea-pigs J Physiol 146 29 53
    • (1959) J Physiol , vol.146 , pp. 29-53
    • Bulbring, E.1    Crema, A.2
  • 9
    • 0001471321 scopus 로고
    • The effect of intraluminal application of 5-hydroxytryptamine and 5-hydroxytryptophan on peristalsis; The local production of 5-HT and its release in relation to intraluminal pressure and propulsive activity
    • E Bulbring RC Lin 1958 The effect of intraluminal application of 5-hydroxytryptamine and 5-hydroxytryptophan on peristalsis; the local production of 5-HT and its release in relation to intraluminal pressure and propulsive activity J Physiol 140 381 407
    • (1958) J Physiol , vol.140 , pp. 381-407
    • Bulbring, E.1    Lin, R.C.2
  • 11
    • 0026074355 scopus 로고
    • Regulation of serotonin release from the intestinal mucosa
    • K Racke H Schworer 1991 Regulation of serotonin release from the intestinal mucosa Pharmacol Res 23 13 25
    • (1991) Pharmacol Res , vol.23 , pp. 13-25
    • Racke, K.1    Schworer, H.2
  • 13
    • 0014259196 scopus 로고
    • Serotonin and the motility of the gastrointestinal tract
    • MD Gershon 1968 Serotonin and the motility of the gastrointestinal tract Gastroenterology 54 453 456
    • (1968) Gastroenterology , vol.54 , pp. 453-456
    • Gershon, M.D.1
  • 14
    • 0034297908 scopus 로고    scopus 로고
    • Serotonin: A mediator of the brain-gut connection
    • DY Kim M Camilleri 2000 Serotonin: A mediator of the brain-gut connection Am J Gastroenterol 95 2698 2709
    • (2000) Am J Gastroenterol , vol.95 , pp. 2698-2709
    • Kim, D.Y.1    Camilleri, M.2
  • 15
    • 84904368711 scopus 로고
    • Review of accidents/injuries among emergency medical services workers in Baltimore, Maryland
    • RR Gershon D Vlahov G Kelen B Conrad L Murphy 1995 Review of accidents/injuries among emergency medical services workers in Baltimore, Maryland Prehospital Disaster Med 10 14 18
    • (1995) Prehospital Disaster Med , vol.10 , pp. 14-18
    • Gershon, R.R.1    Vlahov, D.2    Kelen, G.3    Conrad, B.4    Murphy, L.5
  • 16
    • 10644290207 scopus 로고    scopus 로고
    • Review article: Serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility
    • Suppl 7
    • MD Gershon 2004 Review article: Serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility Aliment Pharmacol Ther 20 Suppl 7 3 14
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 3-14
    • Gershon, M.D.1
  • 17
    • 2342438410 scopus 로고    scopus 로고
    • Enterochromaffin cells and 5-HT signaling in the pathophysiology of disorders of gastrointestinal function
    • MD Crowell MA Shetzline PL Moses GM Mawe NJ Talley 2004 Enterochromaffin cells and 5-HT signaling in the pathophysiology of disorders of gastrointestinal function Curr Opin Investig Drugs 5 55 60
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 55-60
    • Crowell, M.D.1    Shetzline, M.A.2    Moses, P.L.3    Mawe, G.M.4    Talley, N.J.5
  • 18
    • 0029921341 scopus 로고    scopus 로고
    • The enteric nervous system
    • RK Goyal I Hirano 1996 The enteric nervous system N Engl J Med 334 1106 1115
    • (1996) N Engl J Med , vol.334 , pp. 1106-1115
    • Goyal, R.K.1    Hirano, I.2
  • 19
    • 0014136866 scopus 로고
    • 5-hydroxytryptamine participation in the vagal inhibitory innervation of the stomach
    • E Bulbring MD Gershon 1967 5-hydroxytryptamine participation in the vagal inhibitory innervation of the stomach J Physiol 192 823 846
    • (1967) J Physiol , vol.192 , pp. 823-846
    • Bulbring, E.1    Gershon, M.D.2
  • 20
    • 0036016830 scopus 로고    scopus 로고
    • Towards a reduction of rectal pain?
    • D Grundy 2002 Towards a reduction of rectal pain? Neurogastroenterol Motil 14 217 219
    • (2002) Neurogastroenterol Motil , vol.14 , pp. 217-219
    • Grundy, D.1
  • 21
    • 0035041595 scopus 로고    scopus 로고
    • Receptors and transmission in the brain-gut axis: Potential for novel therapies. I. Receptors on visceral afferents
    • AJ Kirkup AM Brunsden D Grundy 2001 Receptors and transmission in the brain-gut axis: Potential for novel therapies. I. Receptors on visceral afferents Am J Physiol Gastrointest Liver Physiol 280 G787 G794
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Kirkup, A.J.1    Brunsden, A.M.2    Grundy, D.3
  • 22
    • 0025652485 scopus 로고
    • Serotonin uptake and serotonin uptake inhibition
    • RW Fuller DT Wong 1990 Serotonin uptake and serotonin uptake inhibition Ann N Y Acad Sci 600 68 80
    • (1990) Ann N Y Acad Sci , vol.600 , pp. 68-80
    • Fuller, R.W.1    Wong, D.T.2
  • 23
    • 0015511125 scopus 로고
    • Storage of 5-hydroxytryptamine in human blood platelets
    • M Da Prada JP Tranzer A Pletscher 1972 Storage of 5-hydroxytryptamine in human blood platelets Experientia 28 1328 1329
    • (1972) Experientia , vol.28 , pp. 1328-1329
    • Da Prada, M.1    Tranzer, J.P.2    Pletscher, A.3
  • 24
    • 0025990688 scopus 로고
    • Serotonin: Its role and receptors in enteric neurotransmission
    • MD Gershon 1991 Serotonin: Its role and receptors in enteric neurotransmission Adv Exp Med Biol 294 221 230
    • (1991) Adv Exp Med Biol , vol.294 , pp. 221-230
    • Gershon, M.D.1
  • 25
    • 0020046977 scopus 로고
    • Depolarizing responses recorded from nodose ganglion cells of the rabbit evoked by 5-hydroxytryptamine and other substances
    • DI Wallis CE Stansfeld HL Nash 1982 Depolarizing responses recorded from nodose ganglion cells of the rabbit evoked by 5-hydroxytryptamine and other substances Neuropharmacology 21 31 40
    • (1982) Neuropharmacology , vol.21 , pp. 31-40
    • Wallis, D.I.1    Stansfeld, C.E.2    Nash, H.L.3
  • 26
    • 28844469346 scopus 로고    scopus 로고
    • Review article: The role of serotonergic agents in the treatment of patients with primary chronic constipation
    • BD Cash WD Chey 2005 Review article: The role of serotonergic agents in the treatment of patients with primary chronic constipation Aliment Pharmacol Ther 22 1047 1060
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 1047-1060
    • Cash, B.D.1    Chey, W.D.2
  • 27
    • 0028670238 scopus 로고
    • Ca2+ permeability of cloned and native 5-hydroxytryptamine type 3 receptors
    • AC Hargreaves SC Lummis CW Taylor 1994 Ca2+ permeability of cloned and native 5-hydroxytryptamine type 3 receptors Mol Pharmacol 46 1120 1128
    • (1994) Mol Pharmacol , vol.46 , pp. 1120-1128
    • Hargreaves, A.C.1    Lummis, S.C.2    Taylor, C.W.3
  • 28
    • 2442581507 scopus 로고    scopus 로고
    • Treating irritable bowel syndrome: Overview, perspective and future therapies
    • M Camilleri 2004 Treating irritable bowel syndrome: Overview, perspective and future therapies Br J Pharmacol 141 1237 1248
    • (2004) Br J Pharmacol , vol.141 , pp. 1237-1248
    • Camilleri, M.1
  • 29
    • 0037295146 scopus 로고    scopus 로고
    • Efficacy of alosetron in irritable bowel syndrome: A meta-analysis of randomized controlled trials
    • F Cremonini S Delgado-Aros M Camilleri 2003 Efficacy of alosetron in irritable bowel syndrome: A meta-analysis of randomized controlled trials Neurogastroenterol Motil 15 79 86
    • (2003) Neurogastroenterol Motil , vol.15 , pp. 79-86
    • Cremonini, F.1    Delgado-Aros, S.2    Camilleri, M.3
  • 30
    • 0031658491 scopus 로고    scopus 로고
    • Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome
    • M Delvaux D Louvel JP Mamet R Campos-Oriola J Frexinos 1998 Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome Aliment Pharmacol Ther 12 849 855
    • (1998) Aliment Pharmacol Ther , vol.12 , pp. 849-855
    • Delvaux, M.1    Louvel, D.2    Mamet, J.P.3    Campos-Oriola, R.4    Frexinos, J.5
  • 31
    • 0032749795 scopus 로고    scopus 로고
    • Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients
    • RH Jones G Holtmann L Rodrigo 1999 Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients Aliment Pharmacol Ther 13 1419 1427
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1419-1427
    • Jones, R.H.1    Holtmann, G.2    Rodrigo, L.3
  • 32
    • 0034827794 scopus 로고    scopus 로고
    • Alosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndrome
    • T Lembo RA Wright B Bagby 2001 Alosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndrome Am J Gastroenterol 96 2662 2670
    • (2001) Am J Gastroenterol , vol.96 , pp. 2662-2670
    • Lembo, T.1    Wright, R.A.2    Bagby, B.3
  • 35
    • 0036089360 scopus 로고    scopus 로고
    • Irritable bowel syndrome neuropharmacology. a review of approved and investigational compounds
    • MJ Callahan 2002 Irritable bowel syndrome neuropharmacology. A review of approved and investigational compounds J Clin Gastroenterol 35 S58 S67
    • (2002) J Clin Gastroenterol , vol.35
    • Callahan, M.J.1
  • 36
  • 38
    • 20044386871 scopus 로고    scopus 로고
    • Tegaserod for the treatment of chronic constipation: A randomized, double-blind, placebo-controlled multinational study
    • MA Kamm S Muller-Lissner NJ Talley 2005 Tegaserod for the treatment of chronic constipation: A randomized, double-blind, placebo-controlled multinational study Am J Gastroenterol 100 362 372
    • (2005) Am J Gastroenterol , vol.100 , pp. 362-372
    • Kamm, M.A.1    Muller-Lissner, S.2    Talley, N.J.3
  • 39
    • 0034794595 scopus 로고    scopus 로고
    • Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
    • SA Muller-Lissner I Fumagalli KD Bardhan 2001 Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation Aliment Pharmacol Ther 15 1655 1666
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1655-1666
    • Muller-Lissner, S.A.1    Fumagalli, I.2    Bardhan, K.D.3
  • 40
    • 1342309961 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome
    • H Nyhlin C Bang L Elsborg 2004 A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome Scand J Gastroenterol 39 119 126
    • (2004) Scand J Gastroenterol , vol.39 , pp. 119-126
    • Nyhlin, H.1    Bang, C.2    Elsborg, L.3
  • 41
    • 0034682643 scopus 로고    scopus 로고
    • Pharmacologic treatment of the irritable bowel syndrome: A systematic review of randomized, controlled trials
    • J Jailwala TF Imperiale K Kroenke 2000 Pharmacologic treatment of the irritable bowel syndrome: A systematic review of randomized, controlled trials Ann Intern Med 133 136 147
    • (2000) Ann Intern Med , vol.133 , pp. 136-147
    • Jailwala, J.1    Imperiale, T.F.2    Kroenke, K.3
  • 42
    • 0036189032 scopus 로고    scopus 로고
    • Review article: The complexity of drug development for irritable bowel syndrome
    • MA Kamm 2002 Review article: The complexity of drug development for irritable bowel syndrome Aliment Pharmacol Ther 16 343 351
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 343-351
    • Kamm, M.A.1
  • 43
    • 3242767685 scopus 로고    scopus 로고
    • Cisapride treatment of constipation-predominant irritable bowel syndrome is not superior to placebo
    • DJ Ziegenhagen W Kruis 2004 Cisapride treatment of constipation- predominant irritable bowel syndrome is not superior to placebo J Gastroenterol Hepatol 19 744 749
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 744-749
    • Ziegenhagen, D.J.1    Kruis, W.2
  • 44
    • 0035121508 scopus 로고    scopus 로고
    • Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder
    • EP Bouras M Camilleri DD Burton G Thomforde S [tmp] McKinzie AR Zinsmeister 2001 Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder Gastroenterology 120 354 360
    • (2001) Gastroenterology , vol.120 , pp. 354-360
    • Bouras, E.P.1    Camilleri, M.2    Burton, D.D.3    Thomforde, G.4    McKinzie, S.5    Zinsmeister, A.R.6
  • 45
    • 0037540068 scopus 로고    scopus 로고
    • Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief. Results of a double-blind, placebo-controlled clinical trial
    • G Coremans R Kerstens M De Pauw M Stevens 2003 Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief. Results of a double-blind, placebo-controlled clinical trial Digestion 67 82 89
    • (2003) Digestion , vol.67 , pp. 82-89
    • Coremans, G.1    Kerstens, R.2    De Pauw, M.3    Stevens, M.4
  • 48
    • 0036109163 scopus 로고    scopus 로고
    • Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation
    • CE Sloots AC Poen R Kerstens 2002 Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation Aliment Pharmacol Ther 16 759 767
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 759-767
    • Sloots, C.E.1    Poen, A.C.2    Kerstens, R.3
  • 49
    • 0033755876 scopus 로고    scopus 로고
    • Effects of a serotonin 5-HT(4) receptor antagonist sb-207266 on gastrointestinal motor and sensory function in humans
    • AE Bharucha M Camilleri S Haydock 2000 Effects of a serotonin 5-HT(4) receptor antagonist sb-207266 on gastrointestinal motor and sensory function in humans Gut 47 667 674
    • (2000) Gut , vol.47 , pp. 667-674
    • Bharucha, A.E.1    Camilleri, M.2    Haydock, S.3
  • 50
    • 0032589965 scopus 로고    scopus 로고
    • 5-HT4 receptor antagonism in irritable bowel syndrome: Effect of sb-207266-a on rectal sensitivity and small bowel transit
    • LA Houghton NA Jackson PJ Whorwell SM Cooper 1999 5-HT4 receptor antagonism in irritable bowel syndrome: Effect of sb-207266-a on rectal sensitivity and small bowel transit Aliment Pharmacol Ther 13 1437 1444
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1437-1444
    • Houghton, L.A.1    Jackson, N.A.2    Whorwell, P.J.3    Cooper, S.M.4
  • 51
    • 0031815458 scopus 로고    scopus 로고
    • Sb-207266: 5-HT4 receptor antagonism in human isolated gut and prevention of 5-HT-evoked sensitization of peristalsis and increased defaecation in animal models
    • GJ Sanger SE Banner MI Smith KA Wardle 1998 Sb-207266: 5-HT4 receptor antagonism in human isolated gut and prevention of 5-HT-evoked sensitization of peristalsis and increased defaecation in animal models Neurogastroenterol Motil 10 271 279
    • (1998) Neurogastroenterol Motil , vol.10 , pp. 271-279
    • Sanger, G.J.1    Banner, S.E.2    Smith, M.I.3    Wardle, K.A.4
  • 52
    • 0033258353 scopus 로고    scopus 로고
    • Review article: Cardiac adverse effects of gastrointestinal prokinetics
    • M Tonini F De Ponti A Di Nucci F Crema 1999 Review article: Cardiac adverse effects of gastrointestinal prokinetics Aliment Pharmacol Ther 13 1585 1591
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1585-1591
    • Tonini, M.1    De Ponti, F.2    Di Nucci, A.3    Crema, F.4
  • 53
    • 5044223521 scopus 로고    scopus 로고
    • Effect of renzapride on transit in constipation-predominant irritable bowel syndrome
    • M Camilleri S [tmp] McKinzie J Fox 2004 Effect of renzapride on transit in constipation-predominant irritable bowel syndrome Clin Gastroenterol Hepatol 2 895 904
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 895-904
    • Camilleri, M.1    McKinzie, S.2    Fox, J.3
  • 54
    • 25844484490 scopus 로고    scopus 로고
    • Basic and clinical pharmacology of new motility promoting agents
    • JJ Galligan S Vanner 2005 Basic and clinical pharmacology of new motility promoting agents Neurogastroenterol Motil 17 643 653
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 643-653
    • Galligan, J.J.1    Vanner, S.2
  • 55
    • 0035197735 scopus 로고    scopus 로고
    • Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-a-gogo k(+) channel
    • F Potet T Bouyssou D Escande I Baro 2001 Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-a-gogo k(+) channel J Pharmacol Exp Ther 299 1007 1012
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 1007-1012
    • Potet, F.1    Bouyssou, T.2    Escande, D.3    Baro, I.4
  • 56
    • 0030801806 scopus 로고    scopus 로고
    • Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro: Implications for proarrhythmic potential?
    • L Carlsson GJ Amos B Andersson L Drews G Duker G Wadstedt 1997 Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro: Implications for proarrhythmic potential? J Pharmacol Exp Ther 282 220 227
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 220-227
    • Carlsson, L.1    Amos, G.J.2    Andersson, B.3    Drews, L.4    Duker, G.5    Wadstedt, G.6
  • 57
    • 0031457583 scopus 로고    scopus 로고
    • Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro
    • Y Mine T Yoshikawa S Oku R Nagai N Yoshida K Hosoki 1997 Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro J Pharmacol Exp Ther 283 1000 1008
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1000-1008
    • Mine, Y.1    Yoshikawa, T.2    Oku, S.3    Nagai, R.4    Yoshida, N.5    Hosoki, K.6
  • 58
    • 0034619541 scopus 로고    scopus 로고
    • The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors
    • PP Bertrand WA Kunze JB Furness JC Bornstein 2000 The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors Neuroscience 101 459 469
    • (2000) Neuroscience , vol.101 , pp. 459-469
    • Bertrand, P.P.1    Kunze, W.A.2    Furness, J.B.3    Bornstein, J.C.4
  • 59
    • 13344276597 scopus 로고    scopus 로고
    • Electrophysiological studies of 5-hydroxytryptamine receptors on enteric neurons
    • JJ Galligan 1996 Electrophysiological studies of 5-hydroxytryptamine receptors on enteric neurons Behav Brain Res 73 199 201
    • (1996) Behav Brain Res , vol.73 , pp. 199-201
    • Galligan, J.J.1
  • 60
    • 0036902330 scopus 로고    scopus 로고
    • Pharmacology of synaptic transmission in the enteric nervous system
    • JJ Galligan 2002 Pharmacology of synaptic transmission in the enteric nervous system Curr Opin Pharmacol 2 623 629
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 623-629
    • Galligan, J.J.1
  • 62
    • 0025219706 scopus 로고
    • Gr 38032f (ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man
    • NJ Talley SF Phillips A Haddad 1990 Gr 38032f (ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man Dig Dis Sci 35 477 480
    • (1990) Dig Dis Sci , vol.35 , pp. 477-480
    • Talley, N.J.1    Phillips, S.F.2    Haddad, A.3
  • 63
    • 0028295092 scopus 로고
    • Serotonergic mediation of postprandial colonic tonic and phasic responses in humans
    • MR von der Ohe RB Hanson M Camilleri 1994 Serotonergic mediation of postprandial colonic tonic and phasic responses in humans Gut 35 536 541
    • (1994) Gut , vol.35 , pp. 536-541
    • Von Der Ohe, M.R.1    Hanson, R.B.2    Camilleri, M.3
  • 64
    • 0034917335 scopus 로고    scopus 로고
    • A randomized controlled clinical trial of the serotonin type 3 receptor antagonist alosetron in women with diarrhea-predominant irritable bowel syndrome
    • M Camilleri WY Chey EA Mayer 2001 A randomized controlled clinical trial of the serotonin type 3 receptor antagonist alosetron in women with diarrhea-predominant irritable bowel syndrome Arch Intern Med 161 1733 1740
    • (2001) Arch Intern Med , vol.161 , pp. 1733-1740
    • Camilleri, M.1    Chey, W.Y.2    Mayer, E.A.3
  • 65
    • 0034712539 scopus 로고    scopus 로고
    • Efficacy and safety of alosetron in women with irritable bowel syndrome: A randomised, placebo-controlled trial
    • M Camilleri AR Northcutt S Kong GE Dukes D [tmp] McSorley AW Mangel 2000 Efficacy and safety of alosetron in women with irritable bowel syndrome: A randomised, placebo-controlled trial Lancet 355 1035 1040
    • (2000) Lancet , vol.355 , pp. 1035-1040
    • Camilleri, M.1    Northcutt, A.R.2    Kong, S.3    Dukes, G.E.4    McSorley, D.5    Mangel, A.W.6
  • 67
    • 0032209507 scopus 로고    scopus 로고
    • 5-HT4 receptor agonists and delta-opioid receptor antagonists act synergistically to stimulate colonic propulsion
    • AE Foxx-Orenstein JG Jin JR Grider 1998 5-HT4 receptor agonists and delta-opioid receptor antagonists act synergistically to stimulate colonic propulsion Am J Physiol 275 G979 G983
    • (1998) Am J Physiol , vol.275
    • Foxx-Orenstein, A.E.1    Jin, J.G.2    Grider, J.R.3
  • 69
    • 33644866358 scopus 로고    scopus 로고
    • Desensitization of the peristaltic reflex induced by mucosal stimulation with the selective 5-HT4 agonist tegaserod
    • JR Grider 2006 Desensitization of the peristaltic reflex induced by mucosal stimulation with the selective 5-HT4 agonist tegaserod Am J Physiol Gastrointest Liver Physiol 290 G319 G327
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Grider, J.R.1
  • 70
    • 0142091274 scopus 로고    scopus 로고
    • Signalling mechanism coupled to 5-hydroxytryptamine4 receptor-mediated facilitation of fast synaptic transmission in the guinea-pig ileum myenteric plexus
    • JJ Galligan H Pan E Messori 2003 Signalling mechanism coupled to 5-hydroxytryptamine4 receptor-mediated facilitation of fast synaptic transmission in the guinea-pig ileum myenteric plexus Neurogastroenterol Motil 15 523 529
    • (2003) Neurogastroenterol Motil , vol.15 , pp. 523-529
    • Galligan, J.J.1    Pan, H.2    Messori, E.3
  • 71
    • 0028210437 scopus 로고
    • 5-HT1a and 5-HT4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neurons
    • H Pan JJ Galligan 1994 5-HT1a and 5-HT4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neurons Am J Physiol 266 G230 G238
    • (1994) Am J Physiol , vol.266
    • Pan, H.1    Galligan, J.J.2
  • 72
    • 0031595212 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine
    • JR Grider AE Foxx-Orenstein JG Jin 1998 5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine Gastroenterology 115 370 380
    • (1998) Gastroenterology , vol.115 , pp. 370-380
    • Grider, J.R.1    Foxx-Orenstein, A.E.2    Jin, J.G.3
  • 73
    • 0032909949 scopus 로고    scopus 로고
    • Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors
    • JG Jin AE Foxx-Orenstein JR Grider 1999 Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors J Pharmacol Exp Ther 288 93 97
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 93-97
    • Jin, J.G.1    Foxx-Orenstein, A.E.2    Grider, J.R.3
  • 75
    • 0001267209 scopus 로고    scopus 로고
    • UK licence for cisapride suspended
    • A Ferriman 2000 UK licence for cisapride suspended BMJ 321 259
    • (2000) BMJ , vol.321 , pp. 259
    • Ferriman, A.1
  • 79
    • 28644450976 scopus 로고    scopus 로고
    • Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction
    • J Wheatcroft D Wakelin A Smith CR Mahoney G Mawe R Spiller 2005 Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction Neurogastroenterol Motil 17 863 870
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 863-870
    • Wheatcroft, J.1    Wakelin, D.2    Smith, A.3    Mahoney, C.R.4    Mawe, G.5    Spiller, R.6
  • 80
    • 33644864860 scopus 로고    scopus 로고
    • Consequences of Citrobacter rodentium infection on enteroendocrine cells and the enteric nervous system in the mouse colon
    • JR O'Hara AC Skinn WK [tmp] MacNaughton PM Sherman KA Sharkey 2006 Consequences of Citrobacter rodentium infection on enteroendocrine cells and the enteric nervous system in the mouse colon Cell Microbiol 8 646 660
    • (2006) Cell Microbiol , vol.8 , pp. 646-660
    • O'Hara, J.R.1    Skinn, A.C.2    MacNaughton, W.K.3    Sherman, P.M.4    Sharkey, K.A.5
  • 81
    • 2942525747 scopus 로고    scopus 로고
    • Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome
    • MD Coates CR Mahoney DR Linden 2004 Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome Gastroenterology 126 1657 1664
    • (2004) Gastroenterology , vol.126 , pp. 1657-1664
    • Coates, M.D.1    Mahoney, C.R.2    Linden, D.R.3
  • 82
    • 0017250212 scopus 로고
    • Enterochromaffin cells in macrophages in ulcerative colitis and irritable colon
    • A Ahonen K Kyosola O Penttila 1976 Enterochromaffin cells in macrophages in ulcerative colitis and irritable colon Ann Clin Res 8 1 7
    • (1976) Ann Clin Res , vol.8 , pp. 1-7
    • Ahonen, A.1    Kyosola, K.2    Penttila, O.3
  • 83
    • 0036149120 scopus 로고    scopus 로고
    • Impaired synthesis or cellular storage of norepinephrine, dopamine, and 5-hydroxytryptamine in human inflammatory bowel disease
    • F Magro MA Vieira-Coelho S Fraga 2002 Impaired synthesis or cellular storage of norepinephrine, dopamine, and 5-hydroxytryptamine in human inflammatory bowel disease Dig Dis Sci 47 216 224
    • (2002) Dig Dis Sci , vol.47 , pp. 216-224
    • Magro, F.1    Vieira-Coelho, M.A.2    Fraga, S.3
  • 85
    • 0031980886 scopus 로고    scopus 로고
    • Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study
    • CP Bearcroft D Perrett MJ Farthing 1998 Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study Gut 42 42 46
    • (1998) Gut , vol.42 , pp. 42-46
    • Bearcroft, C.P.1    Perrett, D.2    Farthing, M.J.3
  • 86
    • 0035020937 scopus 로고    scopus 로고
    • Patients with constipation-predominant irritable bowel syndrome (IBS) may have elevated serotonin concentrations in colonic mucosa as compared with diarrhea-predominant patients and subjects with normal bowel habits
    • J Miwa H Echizen K Matsueda N Umeda 2001 Patients with constipation-predominant irritable bowel syndrome (IBS) may have elevated serotonin concentrations in colonic mucosa as compared with diarrhea-predominant patients and subjects with normal bowel habits Digestion 63 188 194
    • (2001) Digestion , vol.63 , pp. 188-194
    • Miwa, J.1    Echizen, H.2    Matsueda, K.3    Umeda, N.4
  • 87
    • 30044442329 scopus 로고    scopus 로고
    • Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome
    • W Atkinson S Lockhart PJ Whorwell B Keevil LA Houghton 2006 Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome Gastroenterology 130 34 43
    • (2006) Gastroenterology , vol.130 , pp. 34-43
    • Atkinson, W.1    Lockhart, S.2    Whorwell, P.J.3    Keevil, B.4    Houghton, L.A.5
  • 88
    • 16844380691 scopus 로고    scopus 로고
    • Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome
    • SP Dunlop NS Coleman E Blackshaw 2005 Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome Clin Gastroenterol Hepatol 3 349 357
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 349-357
    • Dunlop, S.P.1    Coleman, N.S.2    Blackshaw, E.3
  • 89
    • 0033665517 scopus 로고    scopus 로고
    • Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome
    • RC Spiller D Jenkins JP Thornley 2000 Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome Gut 47 804 811
    • (2000) Gut , vol.47 , pp. 804-811
    • Spiller, R.C.1    Jenkins, D.2    Thornley, J.P.3
  • 90
    • 0345059404 scopus 로고    scopus 로고
    • Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS
    • SP Dunlop D Jenkins KR Neal RC Spiller 2003 Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS Gastroenterology 125 1651 1659
    • (2003) Gastroenterology , vol.125 , pp. 1651-1659
    • Dunlop, S.P.1    Jenkins, D.2    Neal, K.R.3    Spiller, R.C.4
  • 91
    • 0025428179 scopus 로고
    • Serotonin and 5-hydroxyindoleacetic acid are increased in the sigmoid colon in severe idiopathic constipation
    • J Lincoln R Crowe MA Kamm G Burnstock JE Lennard-Jones 1990 Serotonin and 5-hydroxyindoleacetic acid are increased in the sigmoid colon in severe idiopathic constipation Gastroenterology 98 1219 1225
    • (1990) Gastroenterology , vol.98 , pp. 1219-1225
    • Lincoln, J.1    Crowe, R.2    Kamm, M.A.3    Burnstock, G.4    Lennard-Jones, J.E.5
  • 92
    • 0034130854 scopus 로고    scopus 로고
    • Enterochromaffin and serotonin cells are abnormal for patients with colonic inertia
    • R Zhao MK Baig SD Wexner 2000 Enterochromaffin and serotonin cells are abnormal for patients with colonic inertia Dis Colon Rectum 43 858 863
    • (2000) Dis Colon Rectum , vol.43 , pp. 858-863
    • Zhao, R.1    Baig, M.K.2    Wexner, S.D.3
  • 93
    • 0036177386 scopus 로고    scopus 로고
    • Quality of life in inflammatory bowel disease in remission: The impact of IBS-like symptoms and associated psychological factors
    • M Simren J Axelsson R Gillberg H Abrahamsson J Svedlund ES Bjornsson 2002 Quality of life in inflammatory bowel disease in remission: The impact of IBS-like symptoms and associated psychological factors Am J Gastroenterol 97 389 396
    • (2002) Am J Gastroenterol , vol.97 , pp. 389-396
    • Simren, M.1    Axelsson, J.2    Gillberg, R.3    Abrahamsson, H.4    Svedlund, J.5    Bjornsson, E.S.6
  • 94
    • 0030964771 scopus 로고    scopus 로고
    • Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: Postal survey of patients
    • KR Neal J Hebden R Spiller 1997 Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: Postal survey of patients BMJ 314 779 782
    • (1997) BMJ , vol.314 , pp. 779-782
    • Neal, K.R.1    Hebden, J.2    Spiller, R.3
  • 95
    • 0030900827 scopus 로고    scopus 로고
    • Irritable bowel syndrome: A technical review for practice guideline development
    • DA Drossman WE Whitehead M Camilleri 1997 Irritable bowel syndrome: A technical review for practice guideline development Gastroenterology 112 2120 2137
    • (1997) Gastroenterology , vol.112 , pp. 2120-2137
    • Drossman, D.A.1    Whitehead, W.E.2    Camilleri, M.3
  • 96
    • 0036083346 scopus 로고    scopus 로고
    • Activation of the mucosal immune system in irritable bowel syndrome
    • VS Chadwick W Chen D Shu 2002 Activation of the mucosal immune system in irritable bowel syndrome Gastroenterology 122 1778 1783
    • (2002) Gastroenterology , vol.122 , pp. 1778-1783
    • Chadwick, V.S.1    Chen, W.2    Shu, D.3
  • 97
    • 0036893131 scopus 로고    scopus 로고
    • Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome
    • H Tornblom G Lindberg B Nyberg B Veress 2002 Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome Gastroenterology 123 1972 1979
    • (2002) Gastroenterology , vol.123 , pp. 1972-1979
    • Tornblom, H.1    Lindberg, G.2    Nyberg, B.3    Veress, B.4
  • 98
    • 0034107656 scopus 로고    scopus 로고
    • Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention
    • H Mertz V Morgan G Tanner 2000 Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention Gastroenterology 118 842 848
    • (2000) Gastroenterology , vol.118 , pp. 842-848
    • Mertz, H.1    Morgan, V.2    Tanner, G.3
  • 100
    • 0034059773 scopus 로고    scopus 로고
    • Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome
    • S Nobaek ML Johansson G Molin S Ahrne B Jeppsson 2000 Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome Am J Gastroenterol 95 1231 1238
    • (2000) Am J Gastroenterol , vol.95 , pp. 1231-1238
    • Nobaek, S.1    Johansson, M.L.2    Molin, G.3    Ahrne, S.4    Jeppsson, B.5
  • 101
    • 23244446441 scopus 로고    scopus 로고
    • Nerves, reflexes, and the enteric nervous system: Pathogenesis of the irritable bowel syndrome
    • MD Gershon 2005 Nerves, reflexes, and the enteric nervous system: Pathogenesis of the irritable bowel syndrome J Clin Gastroenterol 39 S184 S193
    • (2005) J Clin Gastroenterol , vol.39
    • Gershon, M.D.1
  • 102
    • 0035882382 scopus 로고    scopus 로고
    • Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
    • JJ Chen Z Li H Pan 2001 Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters J Neurosci 21 6348 6361
    • (2001) J Neurosci , vol.21 , pp. 6348-6361
    • Chen, J.J.1    Li, Z.2    Pan, H.3
  • 103
    • 33646711903 scopus 로고    scopus 로고
    • Effects of serotonin transporter inhibition on gastrointestinal motility and colonic sensitivity in the mouse
    • MD Coates AC Johnson B Greenwood-Van Meerveld GM Mawe 2006 Effects of serotonin transporter inhibition on gastrointestinal motility and colonic sensitivity in the mouse Neurogastroenterol Motil 18 464 471
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 464-471
    • Coates, M.D.1    Johnson, A.C.2    Greenwood-Van Meerveld, B.3    Mawe, G.M.4
  • 104
    • 0032848856 scopus 로고    scopus 로고
    • Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5-HT3 receptor antagonist
    • M Camilleri EA Mayer DA Drossman 1999 Improvement in pain and bowel function in female irritable bowel patients with alosetron, a 5-HT3 receptor antagonist Aliment Pharmacol Ther 13 1149 1159
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1149-1159
    • Camilleri, M.1    Mayer, E.A.2    Drossman, D.A.3
  • 105
    • 0035057423 scopus 로고    scopus 로고
    • Irritable bowel syndrome: New agents targeting serotonin receptor subtypes
    • F De Ponti M Tonini 2001 Irritable bowel syndrome: New agents targeting serotonin receptor subtypes Drugs 61 317 332
    • (2001) Drugs , vol.61 , pp. 317-332
    • De Ponti, F.1    Tonini, M.2
  • 106
    • 0033512976 scopus 로고    scopus 로고
    • Outcome of colectomy for slow transit constipation
    • CH Knowles M Scott PJ Lunniss 1999 Outcome of colectomy for slow transit constipation Ann Surg 230 627 638
    • (1999) Ann Surg , vol.230 , pp. 627-638
    • Knowles, C.H.1    Scott, M.2    Lunniss, P.J.3
  • 107
    • 0024536954 scopus 로고
    • Epidemiology of constipation in the United States
    • A Sonnenberg TR Koch 1989 Epidemiology of constipation in the United States Dis Colon Rectum 32 1 8
    • (1989) Dis Colon Rectum , vol.32 , pp. 1-8
    • Sonnenberg, A.1    Koch, T.R.2
  • 109
    • 0033965335 scopus 로고    scopus 로고
    • Decreased interstitial cell of Cajal volume in patients with slow-transit constipation
    • CL He L Burgart L Wang 2000 Decreased interstitial cell of Cajal volume in patients with slow-transit constipation Gastroenterology 118 14 21
    • (2000) Gastroenterology , vol.118 , pp. 14-21
    • He, C.L.1    Burgart, L.2    Wang, L.3
  • 110
    • 4444374536 scopus 로고    scopus 로고
    • Decreased interstitial cells of Cajal in the sigmoid colon of patients with slow transit constipation
    • WD Tong BH Liu LY Zhang SB Zhang Y Lei 2004 Decreased interstitial cells of Cajal in the sigmoid colon of patients with slow transit constipation Int J Colorectal Dis 19 467 473
    • (2004) Int J Colorectal Dis , vol.19 , pp. 467-473
    • Tong, W.D.1    Liu, B.H.2    Zhang, L.Y.3    Zhang, S.B.4    Lei, Y.5
  • 111
    • 0035067359 scopus 로고    scopus 로고
    • Decreased tyrosine kinase C expression may reflect developmental abnormalities in Hirschsprung's disease and idiopathic slow-transit constipation
    • P Facer CH Knowles PK Thomas PK Tam NS Williams P Anand 2001 Decreased tyrosine kinase C expression may reflect developmental abnormalities in Hirschsprung's disease and idiopathic slow-transit constipation Br J Surg 88 545 552
    • (2001) Br J Surg , vol.88 , pp. 545-552
    • Facer, P.1    Knowles, C.H.2    Thomas, P.K.3    Tam, P.K.4    Williams, N.S.5    Anand, P.6
  • 112
    • 0342757550 scopus 로고    scopus 로고
    • Idiopathic slow-transit constipation is not associated with mutations of the ret proto-oncogene or GDNF
    • CH Knowles SA Gayther M Scott 2000 Idiopathic slow-transit constipation is not associated with mutations of the ret proto-oncogene or GDNF Dis Colon Rectum 43 851 857
    • (2000) Dis Colon Rectum , vol.43 , pp. 851-857
    • Knowles, C.H.1    Gayther, S.A.2    Scott, M.3
  • 113
    • 0032972703 scopus 로고    scopus 로고
    • Slow-transit constipation: Solitary symptom of a systemic gastrointestinal disease
    • DF Altomare P Portincasa M Rinaldi 1999 Slow-transit constipation: Solitary symptom of a systemic gastrointestinal disease Dis Colon Rectum 42 231 240
    • (1999) Dis Colon Rectum , vol.42 , pp. 231-240
    • Altomare, D.F.1    Portincasa, P.2    Rinaldi, M.3
  • 114
    • 15744393922 scopus 로고    scopus 로고
    • Role of progesterone signaling in the regulation of g-protein levels in female chronic constipation
    • ZL Xiao V Pricolo P Biancani J Behar 2005 Role of progesterone signaling in the regulation of g-protein levels in female chronic constipation Gastroenterology 128 667 675
    • (2005) Gastroenterology , vol.128 , pp. 667-675
    • Xiao, Z.L.1    Pricolo, V.2    Biancani, P.3    Behar, J.4
  • 116
    • 0023386718 scopus 로고
    • Idiopathic slow-transit constipation: Whole gut transit times, measured by a new simplified method, are not shortened by opioid antagonists
    • KJ Fotherby JO Hunter 1987 Idiopathic slow-transit constipation: Whole gut transit times, measured by a new simplified method, are not shortened by opioid antagonists Aliment Pharmacol Ther 1 331 338
    • (1987) Aliment Pharmacol Ther , vol.1 , pp. 331-338
    • Fotherby, K.J.1    Hunter, J.O.2
  • 117
    • 0021637945 scopus 로고
    • Intestinal pseudo-obstruction related to cytomegalovirus infection of myenteric plexus
    • E Sonsino R Mouy P Foucaud 1984 Intestinal pseudo-obstruction related to cytomegalovirus infection of myenteric plexus N Engl J Med 311 196 197
    • (1984) N Engl J Med , vol.311 , pp. 196-197
    • Sonsino, E.1    Mouy, R.2    Foucaud, P.3
  • 118
    • 0025831241 scopus 로고
    • Oral naloxone in opioid-associated constipation
    • NP Sykes 1991 Oral naloxone in opioid-associated constipation Lancet 337 1475
    • (1991) Lancet , vol.337 , pp. 1475
    • Sykes, N.P.1
  • 119
    • 0025962812 scopus 로고
    • Gastrointestinal motor dysfunction in acquired selective cholinergic dysautonomia associated with infectious mononucleosis
    • M Vassallo M Camilleri BL Caron PA Low 1991 Gastrointestinal motor dysfunction in acquired selective cholinergic dysautonomia associated with infectious mononucleosis Gastroenterology 100 252 258
    • (1991) Gastroenterology , vol.100 , pp. 252-258
    • Vassallo, M.1    Camilleri, M.2    Caron, B.L.3    Low, P.A.4
  • 120
    • 0034073327 scopus 로고    scopus 로고
    • Slow transit constipation: A model of human gut dysmotility. Review of possible aetiologies
    • CH Knowles JE Martin 2000 Slow transit constipation: A model of human gut dysmotility. Review of possible aetiologies Neurogastroenterol Motil 12 181 196
    • (2000) Neurogastroenterol Motil , vol.12 , pp. 181-196
    • Knowles, C.H.1    Martin, J.E.2
  • 121
    • 0037237802 scopus 로고    scopus 로고
    • Reduced expression of serotonin receptor(s) in the left colon of patients with colonic inertia
    • RH Zhao MK Baig KJ Thaler 2003 Reduced expression of serotonin receptor(s) in the left colon of patients with colonic inertia Dis Colon Rectum 46 81 86
    • (2003) Dis Colon Rectum , vol.46 , pp. 81-86
    • Zhao, R.H.1    Baig, M.K.2    Thaler, K.J.3
  • 122
    • 4444245748 scopus 로고    scopus 로고
    • Effect of tegaserod in chronic constipation: A randomized, double-blind, controlled trial
    • JF Johanson A Wald G Tougas 2004 Effect of tegaserod in chronic constipation: A randomized, double-blind, controlled trial Clin Gastroenterol Hepatol 2 796 805
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 796-805
    • Johanson, J.F.1    Wald, A.2    Tougas, G.3
  • 123
    • 0029049097 scopus 로고
    • Colectomy as treatment for constipation in selected patients
    • MF Piccirillo P Reissman SD Wexner 1995 Colectomy as treatment for constipation in selected patients Br J Surg 82 898 901
    • (1995) Br J Surg , vol.82 , pp. 898-901
    • Piccirillo, M.F.1    Reissman, P.2    Wexner, S.D.3
  • 124
    • 0037389903 scopus 로고    scopus 로고
    • Quality of life after subtotal colectomy for slow-transit constipation: Both quality and quantity count
    • GP FitzHarris J Garcia-Aguilar SC Parker 2003 Quality of life after subtotal colectomy for slow-transit constipation: Both quality and quantity count Dis Colon Rectum 46 433 440
    • (2003) Dis Colon Rectum , vol.46 , pp. 433-440
    • Fitzharris, G.P.1    Garcia-Aguilar, J.2    Parker, S.C.3
  • 125
    • 27744564655 scopus 로고    scopus 로고
    • Systematic review: Acute colonic pseudo-obstruction
    • MD Saunders MB Kimmey 2005 Systematic review: Acute colonic pseudo-obstruction Aliment Pharmacol Ther 22 917 925
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 917-925
    • Saunders, M.D.1    Kimmey, M.B.2
  • 126
    • 0034778344 scopus 로고    scopus 로고
    • Review article: The pharmacological treatment of acute colonic pseudo-obstruction
    • R De Giorgio G Barbara V Stanghellini 2001 Review article: The pharmacological treatment of acute colonic pseudo-obstruction Aliment Pharmacol Ther 15 1717 1727
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1717-1727
    • De Giorgio, R.1    Barbara, G.2    Stanghellini, V.3
  • 128
    • 0033565321 scopus 로고    scopus 로고
    • Neostigmine for the treatment of acute colonic pseudo-obstruction
    • RJ Ponec MD Saunders MB Kimmey 1999 Neostigmine for the treatment of acute colonic pseudo-obstruction N Engl J Med 341 137 141
    • (1999) N Engl J Med , vol.341 , pp. 137-141
    • Ponec, R.J.1    Saunders, M.D.2    Kimmey, M.B.3
  • 130
    • 0034033157 scopus 로고    scopus 로고
    • Neostigmine: Safe and effective treatment for acute colonic pseudo-obstruction
    • GT Trevisani NH Hyman JM Church 2000 Neostigmine: Safe and effective treatment for acute colonic pseudo-obstruction Dis Colon Rectum 43 599 603
    • (2000) Dis Colon Rectum , vol.43 , pp. 599-603
    • Trevisani, G.T.1    Hyman, N.H.2    Church, J.M.3
  • 131
    • 0025174815 scopus 로고
    • Treatment of acute colonic pseudo-obstruction (Ogilvie's syndrome) with cisapride
    • C [tmp] MacColl KL [tmp] MacCannell B Baylis SS Lee 1990 Treatment of acute colonic pseudo-obstruction (Ogilvie's syndrome) with cisapride Gastroenterology 98 773 776
    • (1990) Gastroenterology , vol.98 , pp. 773-776
    • MacColl, C.1    MacCannell, K.L.2    Baylis, B.3    Lee, S.S.4


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