Gut flora - Mechanisms of regulation

European Journal of Surgery, Supplement

Volumn 168, Issue 587, 2002, Pages 53-57

  Macpherson, Andrew J ^a   Uhr, Therese ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; TUMOR NECROSIS FACTOR RECEPTOR 1;

B LYMPHOCYTE; BACTERIAL COLONIZATION; BACTERIAL FLORA; BACTERIAL IMMUNITY; BACTERIAL MEMBRANE; COMMENSALISM; CONFERENCE PAPER; EPITHELIUM CELL; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; INTESTINE FLORA; LACTATION; LAMINA PROPRIA; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE; ANIMAL; IMMUNOLOGY; INTESTINE; INTESTINE MUCOSA; MICROBIOLOGY; PEYER PATCH; PHYSIOLOGY; REVIEW;

ANIMALS; EPITHELIAL CELLS; HUMANS; IMMUNOGLOBULIN A; INTESTINAL MUCOSA; INTESTINES; PEYER'S PATCHES;

EID: 0036964196     PISSN: 1102416X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (25)

1. Berg RD. The indigenous gastrointestinal microflora. Trends Microbiol 1996; 4: 430-435.
2. Chen JZ, Trounstine M, Alt F, et al. Immunoglobulin gene rearrangement in B-cell-deficient mice generated by targeted deletion of the J (H) locus. Int Immunol. 1993; 5: 647-656.
3. Craig SW, Cebra JJ. Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J Exp Med 1971; 134: 188-200.
4. De Togni P, Goeliner J, Ruddle R, et al. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 1994; 264: 703-707.
5. Gardby E, Lane P, Lycke NY. Requirements for B7-CD28 costimulation in mucosal IgA responses: paradoxes observed in CTLA4-H gamma 1 transgenic mice. J Immunol 1998; 161: 49-59.
6. Guy-Grand D, Griscelli C, Vassalli P. Peyer's patches, gut IgA plasma cells and thymic function: study in nude mice bearing thymic grafts. J Immunol. 1975; 115: 361-364.
7. Guy-Grand D, Griscelli C, Vassalli P. The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions. J Exp Med 1978; 148: 1661-1677.
8. Harriman GR, Bogue M, Rogers P, et al. Targeted deletion of the IgA constant region in mice leads to IgA deficiency with alterations in expression of other immunoglobulin isotypes. J Immunol 1999; 162: 2521-2529.
9. Hörnquist CE, Ekman L, Grdic KD, Schön K, Lycke NY. Paradoxical IgA immunity in CD4-deficient mice. J Immunol 1995; 155: 2877-2887.
10. Johansen FE, Pekna M, Norderhaug IN, et al. Absence of epithelial immunoglobulin A transport, with increased mucosal leakiness in polymeric immunoglobulin receptor secretory component-deficient mice. J Exp Med 1999; 190: 915-922.
11. Kitamura D, Roes J, Kuhn R, Rajewsky K. A B-cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 1991; 350: 423-426.
12. Kramer DR, Cebra JJ. Role of maternal antibody in the induction of vires specific and bystander IgA responses in Peyer's patches of suckling mice. Int Immunol 1995; 7: 911-918.
13. Lycke N, Eriksen L, Holmgren J. Protection against cholera toxin after oral immunisation is thymus dependent and associated with intestinal production of neutralising IgA antitoxin. Scand J Immunol 1987; 25: 413-419.
14. Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 2000; 288: 2222-2226.
15. Mombaerts P Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 1992; 68: 869-877.
16. Mombaerts PE, Mizoguchi HG, Ljunggren J, et al. Peripheral lymphoid development and function in TCR mutant mice. Int Immunol 1994; 6: 1061-1070.
17. Moreau MC, Ducluzeau R, Guy-Grand D, Muller MC. Increase in the population of duodenal immunoglobulin A plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin. Infect Immun 1978; 21: 532-539.
18. Nanno M, Matsumoto S, Koike R, et al. Development of intestinal intraepithelial T lymphocytes is independent of Peyer's patches and lymph nodes in aly mutant mice. J Immunol 1994; 153: 2014-2020.
19. Pierce NF, Gowans JL. Cellular kinetics of the intestinal immune response to cholera toxoid in rats. J Exp Med 1975; 142: 1550-1563.
20. Schaedler RW, Dubos R, Costello R. Association of germfree mice with bacteria isolated from normal mice. J Exp Med 1965; 122: 77-83.
21. Shiloh MU, MacMicking JD, Nicholson S, et al. Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. Immunity 1999; 10: 29-38.
22. Shroff KE, Meslin K, Cebra JJ. Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infec Immun 1995; 63: 3904-3913.
23. Snider DP, Liang H, Switzer I, Underdown BJ. IgA production in MHC class II-deficient mice is primarily a function of B-1a cells. Int Immunol 1994; 11: 191-198.
24. Vajdy M, Kosco-Vilbois MH, Kopf M, Kohler K, Lycke N. Impaired mucosal immune responses in interleukin 4-targeted mice. J Exp Med 1995; 181: 41-53.
25. Warr GW, Magor KE, Higgins DA. IgY: clues to the origins of modern antibodies. Immunol Today. 1995; 16: 392-398.