Gut microbiota, enteroendocrine functions and metabolism

Current Opinion in Pharmacology

Volumn 13, Issue 6, 2013, Pages 935-940

  Cani, Patrice D ^a   Everard, Amandine ^a   Duparc, Thibaut ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; ENDOCANNABINOID; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; GLUCOSE; PEPTIDE YY; PROTEIN GPR119; PROTEIN GPR41; PROTEIN GPR43; PROTEIN TGR5; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; ENERGY METABOLISM; ENTEROENDOCRINE CELL; ENZYME ACTIVATION; GLUCOSE METABOLISM; HORMONE RELEASE; HOST CELL; HUMAN; INTESTINE FLORA; INTESTINE MUCOSA PERMEABILITY; L CELL; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ANIMALS; ENTEROENDOCRINE CELLS; GASTROINTESTINAL HORMONES; GASTROINTESTINAL TRACT; HUMANS; MICROBIOTA;

EID: 84888201085     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2013.09.008     Document Type: Review

References (61)

1. N.V. Dhurandhar When commonsense does not make sense Int J Obes (Lond) 36 2012 1332 1333
2. N.V. Dhurandhar, L. Geurts, R.L. Atkinson, L. Casteilla, K. Clement, P. Gerard, M. Vijay-Kumar, J.H. Nam, M. Nieuwdorp, and G. Trovato Harnessing the beneficial properties of adipogenic microbes for improving human health Obes Rev 14 2013 721 735
3. N.V. Dhurandhar A framework for identification of infections that contribute to human obesity Lancet Infect Dis 11 2011 963 969
4. L.V. Hooper, and A.J. Macpherson Immune adaptations that maintain homeostasis with the intestinal microbiota Nat Rev Immunol 10 2010 159 169
5. J.L. Round, and S.K. Mazmanian The gut microbiota shapes intestinal immune responses during health and disease Nat Rev Immunol 9 2009 313 323
6. V. Tremaroli, and F. Backhed Functional interactions between the gut microbiota and host metabolism Nature 489 2012 242 249
7. A. des Rieux, V. Pourcelle, P.D. Cani, J. Marchand-Brynaert, and V. Preat Targeted nanoparticles with novel non-peptidic ligands for oral delivery Adv Drug Deliv Rev 65 2013 833 844
8. H.E. Parker, K. Wallis, C.W. Le Roux, K.Y. Wong, F. Reimann, and F.M. Gribble Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion Br J Pharmacol 165 2012 414 423
9. F. Reimann, A.M. Habib, G. Tolhurst, H.E. Parker, G.J. Rogers, and F.M. Gribble Glucose sensing in L cells: a primary cell study Cell Metab 8 2008 532 539
10. N.M. Delzenne, A.M. Neyrinck, F. Backhed, and P.D. Cani Targeting gut microbiota in obesity: effects of prebiotics and probiotics Nat Rev Endocrinol 7 2011 639 646
11. P.D. Cani, C. Knauf, M.A. Iglesias, D.J. Drucker, N.M. Delzenne, and R. Burcelin Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor Diabetes 55 2006 1484 1490 (Pubitemid 44195391)
12. A. Everard, V. Lazarevic, M. Derrien, M. Girard, G.M. Muccioli, A.M. Neyrinck, S. Possemiers, H.A. Van, P. Francois, and W.M. de Vos Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice Diabetes 60 2011 2775 2786
13. A.L. Kau, P.P. Ahern, N.W. Griffin, A.L. Goodman, and J.I. Gordon Human nutrition, the gut microbiome and the immune system Nature 474 2011 327 336
14. G.G. Muccioli, D. Naslain, F. Backhed, C.S. Reigstad, D.M. Lambert, N.M. Delzenne, and P.D. Cani The endocannabinoid system links gut microbiota to adipogenesis Mol Syst Biol 6 2010 392
15. I. Kimura, K. Ozawa, D. Inoue, T. Imamura, K. Kimura, T. Maeda, K. Terasawa, D. Kashihara, K. Hirano, and T. Tani The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 Nat Commun 4 2013 1829
16. E.M. Dewulf, P.D. Cani, A.M. Neyrinck, S. Possemiers, A.V. Holle, G.G. Muccioli, L. Deldicque, L.B. Bindels, B.D. Pachikian, and F.M. Sohet Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARgamma-related adipogenesis in the white adipose tissue of high-fat diet-fed mice J Nutr Biochem 22 2011 712 722
17. K.P. Scott, S.W. Gratz, P.O. Sheridan, H.J. Flint, and S.H. Duncan The influence of diet on the gut microbiota Pharmacol Res 69 2013 52 60
18. J.A. Charrier, R.J. Martin, K.L. McCutcheon, A.M. Raggio, F. Goldsmith, M. Goita, R. Senevirathne, I.L. Brown, C. Pelkman, and J. Zhou High fat diet partially attenuates fermentation responses in rats fed resistant starch from high-amylose maize Obesity (Silver Spring) 21 2013 2350 2355
19. D.R. Donohoe, A. Wali, B.P. Brylawski, and S.J. Bultman Microbial regulation of glucose metabolism and cell-cycle progression in mammalian colonocytes PLOS ONE 7 2012 e46589
20. C. Kruger, K.G. Kumar, R.L. Mynatt, J. Volaufova, and B.K. Richards Brain transcriptional responses to high-fat diet in Acads-deficient mice reveal energy sensing pathways PLOS ONE 7 2012 e41709
21. J. Anastasovska, T. Arora, G.J. Sanchez Canon, J.R. Parkinson, K. Touhy, G.R. Gibson, N.A. Nadkarni, P.W. So, A.P. Goldstone, and E.L. Thomas Fermentable carbohydrate alters hypothalamic neuronal activity and protects against the obesogenic environment Obesity (Silver Spring) 20 2012 1016 1023
22. F. Reimann, G. Tolhurst, and F.M. Gribble G-protein-coupled receptors in intestinal chemosensation Cell Metab 15 2012 421 431
23. P. Plaisancie, V. Dumoulin, J.A. Chayvialle, and J.C. Cuber Luminal glucagon-like peptide-1(7-36) amide-releasing factors in the isolated vascularly perfused rat colon J Endocrinol 145 1995 521 526
24. J. Tarini, and T.M. Wolever The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects Appl Physiol Nutr Metab 35 2010 9 16
25. G. Tolhurst, H. Heffron, Y.S. Lam, H.E. Parker, A.M. Habib, E. Diakogiannaki, J. Cameron, J. Grosse, F. Reimann, and F.M. Gribble Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G protein-coupled receptor FFAR2 Diabetes 61 2012 364 371
26. H.V. Lin, A. Frassetto, E.J. Kowalik Jr., A.R. Nawrocki, M.M. Lu, J.R. Kosinski, J.A. Hubert, D. Szeto, X. Yao, and G. Forrest Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms PLOS ONE 7 2012 e35240
27. Z. Gao, J. Yin, J. Zhang, R.E. Ward, R.J. Martin, M. Lefevre, W.T. Cefalu, and J. Ye Butyrate improves insulin sensitivity and increases energy expenditure in mice Diabetes 58 2009 1509 1517
28. A.J. Brown, S.M. Goldsworthy, A.A. Barnes, M.M. Eilert, L. Tcheang, D. Daniels, A.I. Muir, M.J. Wigglesworth, I. Kinghorn, and N.J. Fraser The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids J Biol Chem 278 2003 11312 11319 (Pubitemid 36792688)
29. F.A. Duca, T.D. Swartz, Y. Sakar, and M. Covasa Increased oral detection, but decreased intestinal signaling for fats in mice lacking gut microbiota PLOS ONE 7 2012 e39748
30. B.S. Samuel, A. Shaito, T. Motoike, F.E. Rey, F. Backhed, J.K. Manchester, R.E. Hammer, S.C. Williams, J. Crowley, and M. Yanagisawa Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 Proc Natl Acad Sci U S A 105 2008 16767 16772
31. I. Kaji, S. Karaki, R. Tanaka, and A. Kuwahara Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide J Mol Histol 42 2011 27 38
32. H. Tazoe, Y. Otomo, S. Karaki, I. Kato, Y. Fukami, M. Terasaki, and A. Kuwahara Expression of short-chain fatty acid receptor GPR41 in the human colon Biomed Res 30 2009 149 156
33. S. Karaki, R. Mitsui, H. Hayashi, I. Kato, H. Sugiya, T. Iwanaga, J.B. Furness, and A. Kuwahara Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine Cell Tissue Res 324 2006 353 360 (Pubitemid 43673476)
34. S.P. Claus, T.M. Tsang, Y. Wang, O. Cloarec, E. Skordi, F.P. Martin, S. Rezzi, A. Ross, S. Kochhar, and E. Holmes Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes Mol Syst Biol 4 2008 219
35. C. Thomas, A. Gioiello, L. Noriega, A. Strehle, J. Oury, G. Rizzo, A. Macchiarulo, H. Yamamoto, C. Mataki, and M. Pruzanski TGR5-mediated bile acid sensing controls glucose homeostasis Cell Metab 10 2009 167 177
36. K. Ma, P.K. Saha, L. Chan, and D.D. Moore Farnesoid X receptor is essential for normal glucose homeostasis J Clin Invest 116 2006 1102 1109
37. S.K. Syed, H.H. Bui, L.S. Beavers, T.B. Farb, J. Ficorilli, A.K. Chesterfield, M.S. Kuo, K. Bokvist, D.G. Barrett, and A.M. Efanov Regulation of GPR119 receptor activity with endocannabinoid-like lipids Am J Physiol Endocrinol Metab 303 2012 E1469 E1478
38. L.M. Lauffer, R. Iakoubov, and P.L. Brubaker GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell Diabetes 58 2009 1058 1066
39. K.B. Hansen, M.M. Rosenkilde, F.K. Knop, N. Wellner, T.A. Diep, J.F. Rehfeld, U.B. Andersen, J.J. Holst, and H.S. Hansen 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans J Clin Endocrinol Metab 96 2011 E1409 E1417
40. M. Derrien, E.E. Vaughan, C.M. Plugge, and W.M. de Vos Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium Int J Syst Evol Microbiol 54 2004 1469 1476 (Pubitemid 39359958)
41. A. Everard, C. Belzer, L. Geurts, J.P. Ouwerkerk, C. Druart, L.B. Bindels, Y. Guiot, M. Derrien, G.G. Muccioli, and N.M. Delzenne Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity Proc Natl Acad Sci U S A 110 2013 9066 9071
42. P.D. Cani, J. Amar, M.A. Iglesias, M. Poggi, C. Knauf, D. Bastelica, A.M. Neyrinck, F. Fava, K.M. Tuohy, and C. Chabo Metabolic endotoxemia initiates obesity and insulin resistance Diabetes 56 2007 1761 1772 (Pubitemid 47025442)
43. P.D. Cani, R. Bibiloni, C. Knauf, A. Waget, A.M. Neyrinck, N.M. Delzenne, and R. Burcelin Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice Diabetes 57 2008 1470 1481
44. P. Brun, I. Castagliuolo, V.D. Leo, A. Buda, M. Pinzani, G. Palu, and D. Martines Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis Am J Physiol Gastrointest Liver Physiol 292 2007 G518 G525
45. J. Amar, M. Serino, C. Lange, C. Chabo, J. Iacovoni, S. Mondot, P. Lepage, C. Klopp, J. Mariette, and O. Bouchez Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept Diabetologia 54 2011 3055 3061
46. R.E. Ley, F. Backhed, P. Turnbaugh, C.A. Lozupone, R.D. Knight, and J.I. Gordon Obesity alters gut microbial ecology Proc Natl Acad Sci U S A 102 2005 11070 11075 (Pubitemid 41105994)
47. J. Qin, Y. Li, Z. Cai, S. Li, J. Zhu, F. Zhang, S. Liang, W. Zhang, Y. Guan, and D. Shen A metagenome-wide association study of gut microbiota in type 2 diabetes Nature 490 2012 55 60
48. F.H. Karlsson, V. Tremaroli, I. Nookaew, G. Bergstrom, C.J. Behre, B. Fagerberg, J. Nielsen, and F. Backhed Gut metagenome in European women with normal, impaired and diabetic glucose control Nature 498 2013 99 103
49. A. Everard, and P.D. Cani Diabetes, obesity and gut microbiota Best Pract Res Clin Gastroenterol 27 2013 73 83
50. P.D. Cani, A.M. Neyrinck, F. Fava, C. Knauf, R.G. Burcelin, K.M. Tuohy, G.R. Gibson, and N.M. Delzenne Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia Diabetologia 50 2007 2374 2383 (Pubitemid 47512397)
51. A.M. Neyrinck, V.F. Van Hee, N. Piront, F. De Backer, O. Toussaint, P.D. Cani, and N.M. Delzenne Wheat-derived arabinoxylan oligosaccharides with prebiotic effect increase satietogenic gut peptides and reduce metabolic endotoxemia in diet-induced obese mice Nutr Diabetes 2 2012 e28
52. D.J. Drucker, P. Erlich, S.L. Asa, and P.L. Brubaker Induction of intestinal epithelial proliferation by glucagon-like peptide 2 Proc Natl Acad Sci U S A 93 1996 7911 7916 (Pubitemid 26277138)
53. P.D. Cani, S. Possemiers, W.T. Van de, Y. Guiot, A. Everard, O. Rottier, L. Geurts, D. Naslain, A.M. Neyrinck, and D.M. Lambert Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability Gut 58 2009 1091 1103
54. G.W. Moran, C. O'Neill, and J.T. McLaughlin GLP-2 enhances barrier formation and attenuates TNFalpha-induced changes in a Caco-2 cell model of the intestinal barrier Regul Pept 178 2012 95 101
55. S.J. Lee, J. Lee, K.K. Li, D. Holland, H. Maughan, D.S. Guttman, B. Yusta, and D.J. Drucker Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis Endocrinology 153 2012 1141 1151
56. C.W. Png, S.K. Linden, K.S. Gilshenan, E.G. Zoetendal, C.S. McSweeney, L.I. Sly, M.A. McGuckin, and T.H. Florin Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria Am J Gastroenterol 105 2010 2420 2428
57. A. Santacruz, M.C. Collado, L. Garcia-Valdes, M.T. Segura, J.A. Martin-Lagos, T. Anjos, M. Marti-Romero, R.M. Lopez, J. Florido, and C. Campoy Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women Br J Nutr 104 2010 83 92
58. S. Haub, Y. Ritze, I. Ladel, K. Saum, A. Hubert, A. Spruss, C. Trautwein, and S.C. Bischoff Serotonin receptor type 3 antagonists improve obesity-associated fatty liver disease in mice J Pharmacol Exp Ther 339 2011 790 798
59. R.L. Bertrand, S. Senadheera, I. Markus, L. Liu, L. Howitt, H. Chen, T.V. Murphy, S.L. Sandow, and P.P. Bertrand A Western diet increases serotonin availability in rat small intestine Endocrinology 152 2011 36 47
60. P. Bercik, E. Denou, J. Collins, W. Jackson, J. Lu, J. Jury, Y. Deng, P. Blennerhassett, J. Macri, and K.D. McCoy The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice Gastroenterology 141 2011 599 609 e591-e593
61. R. Nishino, K. Mikami, H. Takahashi, S. Tomonaga, M. Furuse, T. Hiramoto, Y. Aiba, Y. Koga, and N. Sudo Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods Neurogastroenterol Motil 25 2013 521 528