-
1
-
-
84919385996
-
Dendritic cell IL-1alpha and IL-1beta are polyubiquitinated and degraded by the proteasome
-
Ainscough, J. S., Frank Gerberick, G., Zahedi-Nejad, M., Lopez-Castejon, G., Brough, D., Kimber, I., et al. (2014). Dendritic cell IL-1alpha and IL-1beta are polyubiquitinated and degraded by the proteasome. J. Biol. Chem. 289, 35582-35592. doi: 10.1074/jbc.M114.595686
-
(2014)
J. Biol. Chem
, vol.289
, pp. 35582-35592
-
-
Ainscough, J.S.1
Frank Gerberick, G.2
Zahedi-Nejad, M.3
Lopez-Castejon, G.4
Brough, D.5
Kimber, I.6
-
2
-
-
84903855385
-
The P2X7 receptor: shifting from a low-to a high-conductance channel-an enigmatic phenomenon?
-
Alves, L. A., de Melo Reis, R. A., de Souza, C. A., de Freitas, M. S., Teixeira, P. C., Neto Moreira Ferreira, D., et al. (2014). The P2X7 receptor: shifting from a low-to a high-conductance channel-an enigmatic phenomenon? Biochim. Biophys. Acta 1838, 2578-2587. doi: 10.1016/j.bbamem.2014.05.015
-
(2014)
Biochim. Biophys. Acta
, vol.1838
, pp. 2578-2587
-
-
Alves, L.A.1
de Melo Reis, R.A.2
de Souza, C.A.3
de Freitas, M.S.4
Teixeira, P.C.5
Neto Moreira Ferreira, D.6
-
3
-
-
0032923377
-
The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles
-
Andrei, C., Dazzi, C., Lotti, L., Torrisi, M. R., Chimini, G., and Rubartelli, A. (1999). The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles. Mol. Biol. Cell 10, 1463-1475. doi: 10.1091/mbc.10.5.1463
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 1463-1475
-
-
Andrei, C.1
Dazzi, C.2
Lotti, L.3
Torrisi, M.R.4
Chimini, G.5
Rubartelli, A.6
-
4
-
-
3042800587
-
Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes
-
Andrei, C., Margiocco, P., Poggi, A., Lotti, L. V., Torrisi, M. R., and Rubartelli, A. (2004). Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes. Proc. Natl. Acad. Sci. U.S.A. 101, 9745-9750. doi: 10.1073/pnas.0308558101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 9745-9750
-
-
Andrei, C.1
Margiocco, P.2
Poggi, A.3
Lotti, L.V.4
Torrisi, M.R.5
Rubartelli, A.6
-
5
-
-
84857998516
-
Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism
-
Antonucci, F., Turola, E., Riganti, L., Caleo, M., Gabrielli, M., Perrotta, C., et al. (2012). Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism. EMBO J. 31, 1231-1240. doi: 10.1038/emboj.2011.489
-
(2012)
EMBO J
, vol.31
, pp. 1231-1240
-
-
Antonucci, F.1
Turola, E.2
Riganti, L.3
Caleo, M.4
Gabrielli, M.5
Perrotta, C.6
-
6
-
-
84870055576
-
The participation of plasma membrane hemichannels to purinergic signaling
-
Baroja-Mazo, A., Barbera-Cremades, M., and Pelegrin, P. (2013). The participation of plasma membrane hemichannels to purinergic signaling. Biochim. Biophys. Acta 1828, 79-93. doi: 10.1016/j.bbamem.2012.01.002
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 79-93
-
-
Baroja-Mazo, A.1
Barbera-Cremades, M.2
Pelegrin, P.3
-
7
-
-
84908232996
-
The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease
-
Bartlett, R., Stokes, L., and Sluyter, R. (2014). The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease. Pharmacol. Rev. 66, 638-675. doi: 10.1124/pr.113.008003
-
(2014)
Pharmacol. Rev
, vol.66
, pp. 638-675
-
-
Bartlett, R.1
Stokes, L.2
Sluyter, R.3
-
8
-
-
0000302792
-
Temperature-elevating effect of a substance obtained from polymorphonuclear leucocytes
-
Beeson, P. B. (1948). Temperature-elevating effect of a substance obtained from polymorphonuclear leucocytes. J. Clin. Invest. 27, 524.
-
(1948)
J. Clin. Invest
, vol.27
, pp. 524
-
-
Beeson, P.B.1
-
9
-
-
51849103168
-
The microbial and danger signals that activate Nod-like receptors
-
Benko, S., Philpott, D. J., and Girardin, S. E. (2008). The microbial and danger signals that activate Nod-like receptors. Cytokine 43, 368-373. doi: 10.1016/j.cyto.2008.07.013
-
(2008)
Cytokine
, vol.43
, pp. 368-373
-
-
Benko, S.1
Philpott, D.J.2
Girardin, S.E.3
-
10
-
-
58449083290
-
Pyroptosis: host cell death and inflammation
-
Bergsbaken, T., Fink, S. L., and Cookson, B. T. (2009). Pyroptosis: host cell death and inflammation. Nat. Rev. Microbiol. 7, 99-109. doi: 10.1038/nrmicro2070
-
(2009)
Nat. Rev. Microbiol
, vol.7
, pp. 99-109
-
-
Bergsbaken, T.1
Fink, S.L.2
Cookson, B.T.3
-
11
-
-
67349114201
-
Acid sphingomyelinase activity triggers microparticle release from glial cells
-
Bianco, F., Perrotta, C., Novellino, L., Francolini, M., Riganti, L., Menna, E., et al. (2009). Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J. 28, 1043-1054. doi: 10.1038/emboj.2009.45
-
(2009)
EMBO J
, vol.28
, pp. 1043-1054
-
-
Bianco, F.1
Perrotta, C.2
Novellino, L.3
Francolini, M.4
Riganti, L.5
Menna, E.6
-
12
-
-
18944380607
-
Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia
-
Bianco, F., Pravettoni, E., Colombo, A., Schenk, U., Moller, T., Matteoli, M., et al. (2005). Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J. Immunol. 174, 7268-7277. doi: 10.4049/jimmunol.174.11.7268
-
(2005)
J. Immunol
, vol.174
, pp. 7268-7277
-
-
Bianco, F.1
Pravettoni, E.2
Colombo, A.3
Schenk, U.4
Moller, T.5
Matteoli, M.6
-
14
-
-
0014192623
-
Release of endogenous pyrogen by human monocytes
-
Bodel, P., and Atkins, E. (1967). Release of endogenous pyrogen by human monocytes. N. Engl. J. Med. 276, 1002-1008. doi: 10.1056/NEJM196705042761803
-
(1967)
N. Engl. J. Med
, vol.276
, pp. 1002-1008
-
-
Bodel, P.1
Atkins, E.2
-
15
-
-
84961801288
-
The IL-1 cytokine family and its role in inflammation and fibrosis in the lung
-
Borthwick, L. A. (2016). The IL-1 cytokine family and its role in inflammation and fibrosis in the lung. Semin. Immunopathol. 38, 517-534. doi: 10.1007/s00281-016-0559-z
-
(2016)
Semin. Immunopathol
, vol.38
, pp. 517-534
-
-
Borthwick, L.A.1
-
16
-
-
33749261659
-
Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
-
Bours, M. J., Swennen, E. L., Di Virgilio, F., Cronstein, B. N., and Dagnelie, P. C. (2006). Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol. Ther. 112, 358-404. doi: 10.1016/j.pharmthera.2005.04.013
-
(2006)
Pharmacol. Ther
, vol.112
, pp. 358-404
-
-
Bours, M.J.1
Swennen, E.L.2
Di Virgilio, F.3
Cronstein, B.N.4
Dagnelie, P.C.5
-
17
-
-
0037443542
-
Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages
-
Brough, D., Le Feuvre, R. A., Wheeler, R. D., Solovyova, N., Hilfiker, S., Rothwell, N. J., et al. (2003). Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages. J. Immunol. 170, 3029-3036. doi: 10.4049/jimmunol.170.6.3029
-
(2003)
J. Immunol
, vol.170
, pp. 3029-3036
-
-
Brough, D.1
Le Feuvre, R.A.2
Wheeler, R.D.3
Solovyova, N.4
Hilfiker, S.5
Rothwell, N.J.6
-
18
-
-
84976516826
-
Inflammasomes: mechanism of assembly, regulation and signalling
-
Broz, P., and Dixit, V. M. (2016). Inflammasomes: mechanism of assembly, regulation and signalling. Nat. Rev. Immunol. 16, 407-420. doi: 10.1038/nri.2016.58
-
(2016)
Nat. Rev. Immunol
, vol.16
, pp. 407-420
-
-
Broz, P.1
Dixit, V.M.2
-
19
-
-
0035189834
-
Electrodiffusional ATP movement through CFTR and other ABC transporters
-
Cantiello, H. F. (2001). Electrodiffusional ATP movement through CFTR and other ABC transporters. Pflugers. Arch. 443(Suppl. 1), S22-S27. doi: 10.1007/s004240100639
-
(2001)
Pflugers. Arch
, vol.443
, pp. S22-S27
-
-
Cantiello, H.F.1
-
20
-
-
33748135979
-
Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules
-
Carta, S., Tassi, S., Semino, C., Fossati, G., Mascagni, P., Dinarello, C. A., et al. (2006). Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood 108, 1618-1626. doi: 10.1182/blood-2006-03-014126
-
(2006)
Blood
, vol.108
, pp. 1618-1626
-
-
Carta, S.1
Tassi, S.2
Semino, C.3
Fossati, G.4
Mascagni, P.5
Dinarello, C.A.6
-
21
-
-
84959559428
-
Purinergic regulation of the immune system
-
Cekic, C., and Linden, J. (2016). Purinergic regulation of the immune system. Nat. Rev. Immunol. 16, 177-192. doi: 10.1038/nri.2016.4
-
(2016)
Nat. Rev. Immunol
, vol.16
, pp. 177-192
-
-
Cekic, C.1
Linden, J.2
-
22
-
-
84930982265
-
ATP release through pannexon channels
-
Dahl, G. (2015). ATP release through pannexon channels. Philos. Trans. R. Soc. Lond. B Biol. Sci. 370:20140191. doi: 10.1098/rstb.2014.0191
-
(2015)
Philos. Trans. R. Soc. Lond. B Biol. Sci
, vol.370
-
-
Dahl, G.1
-
23
-
-
84952690683
-
P2X7 receptor as a therapeutic target
-
De Marchi, E., Orioli, E., Dal Ben, D., and Adinolfi, E. (2016). P2X7 receptor as a therapeutic target. Adv. Protein Chem. Struct. Biol. 104, 39-79. doi: 10.1016/bs.apcsb.2015.11.004
-
(2016)
Adv. Protein Chem. Struct. Biol
, vol.104
, pp. 39-79
-
-
De Marchi, E.1
Orioli, E.2
Dal Ben, D.3
Adinolfi, E.4
-
24
-
-
0028850665
-
The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death
-
Di Virgilio, F. (1995). The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death. Immunol. Today 16, 524-528. doi: 10.1016/0167-5699(95)80045-X
-
(1995)
Immunol. Today
, vol.16
, pp. 524-528
-
-
Di Virgilio, F.1
-
25
-
-
0034601273
-
Dr. Jekyll/Mr. Hyde: the dual role of extracellular ATP
-
Di Virgilio, F. (2000). Dr. Jekyll/Mr. Hyde: the dual role of extracellular ATP. J. Auton. Nerv. Syst. 81, 59-63. doi: 10.1016/S0165-1838(00)00114-4
-
(2000)
J. Auton. Nerv. Syst
, vol.81
, pp. 59-63
-
-
Di Virgilio, F.1
-
26
-
-
84876350807
-
The therapeutic potential of modifying inflammasomes and NOD-like receptors
-
Di Virgilio, F. (2013). The therapeutic potential of modifying inflammasomes and NOD-like receptors. Pharmacol. Rev. 65, 872-905. doi: 10.1124/pr.112.006171
-
(2013)
Pharmacol. Rev
, vol.65
, pp. 872-905
-
-
Di Virgilio, F.1
-
27
-
-
84926471604
-
P2X receptors and inflammation
-
Di Virgilio, F. (2015). P2X receptors and inflammation. Curr. Med. Chem. 22, 866-877. doi: 10.2174/0929867322666141210155311
-
(2015)
Curr. Med. Chem
, vol.22
, pp. 866-877
-
-
Di Virgilio, F.1
-
28
-
-
0031822940
-
Cytolytic P2X purinoceptors
-
Di Virgilio, F., Chiozzi, P., Falzoni, S., Ferrari, D., Sanz, J. M., Venketaraman, V., et al. (1998). Cytolytic P2X purinoceptors. Cell Death Differ. 5, 191-199. doi: 10.1038/sj.cdd.4400341
-
(1998)
Cell Death Differ
, vol.5
, pp. 191-199
-
-
Di Virgilio, F.1
Chiozzi, P.2
Falzoni, S.3
Ferrari, D.4
Sanz, J.M.5
Venketaraman, V.6
-
29
-
-
0030338479
-
P2 purinoceptors in the immune system
-
discussion302-295
-
Di Virgilio, F., Ferrari, D., Falzoni, S., Chiozzi, P., Munerati, M., Steinberg, T. H., et al. (1996). P2 purinoceptors in the immune system. Ciba Found. Symp. 198, 290-302; discussion302-295.
-
(1996)
Ciba Found. Symp
, vol.198
, pp. 290-302
-
-
Di Virgilio, F.1
Ferrari, D.2
Falzoni, S.3
Chiozzi, P.4
Munerati, M.5
Steinberg, T.H.6
-
30
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello, C. A. (1996). Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
31
-
-
18644374105
-
Blocking IL-1 in systemic inflammation
-
Dinarello, C. A. (2005). Blocking IL-1 in systemic inflammation. J. Exp. Med. 201, 1355-1359. doi: 10.1084/jem.20050640
-
(2005)
J. Exp. Med
, vol.201
, pp. 1355-1359
-
-
Dinarello, C.A.1
-
32
-
-
79953813107
-
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
-
Dinarello, C. A. (2011). Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117, 3720-3732. doi: 10.1182/blood-2010-07-273417
-
(2011)
Blood
, vol.117
, pp. 3720-3732
-
-
Dinarello, C.A.1
-
33
-
-
0019863205
-
Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro
-
Dinarello, C. A., and Bernheim, H. A. (1981). Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro. J. Neurochem. 37, 702-708. doi: 10.1111/j.1471-4159.1982.tb12544.x
-
(1981)
J. Neurochem
, vol.37
, pp. 702-708
-
-
Dinarello, C.A.1
Bernheim, H.A.2
-
34
-
-
36349004825
-
Go it alone no more-P2X7 joins the society of heteromeric ATP-gated receptor channels
-
Dubyak, G. R. (2007). Go it alone no more-P2X7 joins the society of heteromeric ATP-gated receptor channels. Mol. Pharmacol. 72, 1402-1405. doi: 10.1124/mol.107.042077
-
(2007)
Mol. Pharmacol
, vol.72
, pp. 1402-1405
-
-
Dubyak, G.R.1
-
35
-
-
84867652682
-
P2X7 receptor regulation of non-classical secretion from immune effector cells
-
Dubyak, G. R. (2012). P2X7 receptor regulation of non-classical secretion from immune effector cells. Cell Microbiol. 14, 1697-1706. doi: 10.1111/cmi.12001
-
(2012)
Cell Microbiol
, vol.14
, pp. 1697-1706
-
-
Dubyak, G.R.1
-
36
-
-
68649102975
-
Mechanisms of interleukin-1beta release
-
Eder, C. (2009). Mechanisms of interleukin-1beta release. Immunobiology 214, 543-553. doi: 10.1016/j.imbio.2008.11.007
-
(2009)
Immunobiology
, vol.214
, pp. 543-553
-
-
Eder, C.1
-
37
-
-
84871048026
-
Purinergic signaling during inflammation
-
Eltzschig, H. K., Sitkovsky, M. V., and Robson, S. C. (2012). Purinergic signaling during inflammation. N. Engl. J. Med. 367, 2322-2333. doi: 10.1056/NEJMra1205750
-
(2012)
N. Engl. J. Med
, vol.367
, pp. 2322-2333
-
-
Eltzschig, H.K.1
Sitkovsky, M.V.2
Robson, S.C.3
-
38
-
-
33745528139
-
The gap junction cellular internet: connexin hemichannels enter the signalling limelight
-
Evans, W. H., De Vuyst, E., and Leybaert, L. (2006). The gap junction cellular internet: connexin hemichannels enter the signalling limelight. Biochem. J. 397, 1-14. doi: 10.1042/BJ20060175
-
(2006)
Biochem. J
, vol.397
, pp. 1-14
-
-
Evans, W.H.1
De Vuyst, E.2
Leybaert, L.3
-
39
-
-
84934917374
-
Toll-like receptors 2,-3 and-4 prime microglia but not astrocytes across central nervous system regions for ATP-dependent interleukin-1beta release
-
Facci, L., Barbierato, M., Marinelli, C., Argentini, C., Skaper, S. D., and Giusti, P. (2014). Toll-like receptors 2,-3 and-4 prime microglia but not astrocytes across central nervous system regions for ATP-dependent interleukin-1beta release. Sci. Rep. 4:6824. doi: 10.1038/srep06824
-
(2014)
Sci. Rep
, vol.4
, pp. 6824
-
-
Facci, L.1
Barbierato, M.2
Marinelli, C.3
Argentini, C.4
Skaper, S.D.5
Giusti, P.6
-
40
-
-
0031568401
-
Response to local inflammation of IL-1 beta-converting enzyme-deficient mice
-
Fantuzzi, G., Ku, G., Harding, M. W., Livingston, D. J., Sipe, J. D., Kuida, K., et al. (1997). Response to local inflammation of IL-1 beta-converting enzyme-deficient mice. J. Immunol. 158, 1818-1824.
-
(1997)
J. Immunol
, vol.158
, pp. 1818-1824
-
-
Fantuzzi, G.1
Ku, G.2
Harding, M.W.3
Livingston, D.J.4
Sipe, J.D.5
Kuida, K.6
-
41
-
-
0031201476
-
Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages
-
Ferrari, D., Chiozzi, P., Falzoni, S., Dal Susino, M., Melchiorri, L., Baricordi, O. R., et al. (1997). Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 159, 1451-1458.
-
(1997)
J. Immunol
, vol.159
, pp. 1451-1458
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Dal Susino, M.4
Melchiorri, L.5
Baricordi, O.R.6
-
42
-
-
33646072818
-
The P2X7 receptor: a key player in IL-1 processing and release
-
Ferrari, D., Pizzirani, C., Adinolfi, E., Lemoli, R. M., Curti, A., Idzko, M., et al. (2006). The P2X7 receptor: a key player in IL-1 processing and release. J. Immunol. 176, 3877-3883. doi: 10.4049/jimmunol.176.7.3877
-
(2006)
J. Immunol
, vol.176
, pp. 3877-3883
-
-
Ferrari, D.1
Pizzirani, C.2
Adinolfi, E.3
Lemoli, R.M.4
Curti, A.5
Idzko, M.6
-
43
-
-
0030022576
-
Mouse microglial cells express a plasma membrane pore gated by extracellular ATP
-
Ferrari, D., Villalba, M., Chiozzi, P., Falzoni, S., Ricciardi-Castagnoli, P., and Di Virgilio, F. (1996). Mouse microglial cells express a plasma membrane pore gated by extracellular ATP. J. Immunol. 156, 1531-1539.
-
(1996)
J. Immunol
, vol.156
, pp. 1531-1539
-
-
Ferrari, D.1
Villalba, M.2
Chiozzi, P.3
Falzoni, S.4
Ricciardi-Castagnoli, P.5
Di Virgilio, F.6
-
44
-
-
84933557676
-
The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein
-
Franceschini, A., Capece, M., Chiozzi, P., Falzoni, S., Sanz, J. M., Sarti, A. C., et al. (2015). The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein. FASEB J. 29, 2450-2461. doi: 10.1096/fj.14-268714
-
(2015)
FASEB J
, vol.29
, pp. 2450-2461
-
-
Franceschini, A.1
Capece, M.2
Chiozzi, P.3
Falzoni, S.4
Sanz, J.M.5
Sarti, A.C.6
-
45
-
-
77950627242
-
IL-1 pathways in inflammation and human diseases
-
Gabay, C., Lamacchia, C., and Palmer, G. (2010). IL-1 pathways in inflammation and human diseases. Nat. Rev. Rheumatol. 6, 232-241. doi: 10.1038/nrrheum.2010.4
-
(2010)
Nat. Rev. Rheumatol
, vol.6
, pp. 232-241
-
-
Gabay, C.1
Lamacchia, C.2
Palmer, G.3
-
46
-
-
0032695108
-
Natural adjuvants: endogenous activators of dendritic cells
-
Gallucci, S., Lolkema, M., and Matzinger, P. (1999). Natural adjuvants: endogenous activators of dendritic cells. Nat. Med. 5, 1249-1255. doi: 10.1038/15200
-
(1999)
Nat. Med
, vol.5
, pp. 1249-1255
-
-
Gallucci, S.1
Lolkema, M.2
Matzinger, P.3
-
47
-
-
84890235827
-
The interleukin-1 family: back to the future
-
Garlanda, C., Dinarello, C. A., and Mantovani, A. (2013). The interleukin-1 family: back to the future. Immunity 39, 1003-1018. doi: 10.1016/j.immuni.2013.11.010
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
Dinarello, C.A.2
Mantovani, A.3
-
48
-
-
0015365707
-
Potentiation of the T-lymphocyte response to mitogens. II. The cellular source of potentiating mediator(s)
-
Gery, I., and Waksman, B. H. (1972). Potentiation of the T-lymphocyte response to mitogens. II. The cellular source of potentiating mediator(s). J. Exp. Med. 136, 143-155. doi: 10.1084/jem.136.1.143
-
(1972)
J. Exp. Med
, vol.136
, pp. 143-155
-
-
Gery, I.1
Waksman, B.H.2
-
49
-
-
33749354009
-
Osteoporosis, inflammation and ageing
-
Ginaldi, L., Di Benedetto, M. C., and De Martinis, M. (2005). Osteoporosis, inflammation and ageing. Immun. Ageing 2:14. doi: 10.1186/1742-4933-2-14
-
(2005)
Immun. Ageing
, vol.2
, pp. 14
-
-
Ginaldi, L.1
Di Benedetto, M.C.2
De Martinis, M.3
-
50
-
-
84926436169
-
Purinergic P2X receptors: structural and functional features depicted by X-ray and molecular modelling studies
-
Grimes, L., and Young, M. T. (2015). Purinergic P2X receptors: structural and functional features depicted by X-ray and molecular modelling studies. Curr. Med. Chem. 22, 783-798. doi: 10.2174/0929867321999141212131457
-
(2015)
Curr. Med. Chem
, vol.22
, pp. 783-798
-
-
Grimes, L.1
Young, M.T.2
-
51
-
-
0042242912
-
Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
-
Gudipaty, L., Munetz, J., Verhoef, P. A., and Dubyak, G. R. (2003). Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am. J. Physiol. Cell Physiol. 285, C286-C299. doi: 10.1152/ajpcell.00070.2003
-
(2003)
Am. J. Physiol. Cell Physiol
, vol.285
, pp. C286-C299
-
-
Gudipaty, L.1
Munetz, J.2
Verhoef, P.A.3
Dubyak, G.R.4
-
52
-
-
84936891896
-
Inflammasomes: mechanism of action, role in disease, and therapeutics
-
Guo, H., Callaway, J. B., and Ting, J. P. (2015). Inflammasomes: mechanism of action, role in disease, and therapeutics. Nat. Med. 21, 677-687. doi: 10.1038/nm.3893
-
(2015)
Nat. Med
, vol.21
, pp. 677-687
-
-
Guo, H.1
Callaway, J.B.2
Ting, J.P.3
-
53
-
-
84937690389
-
Barrier epithelial cells and the control of type 2 immunity
-
Hammad, H., and Lambrecht, B. N. (2015). Barrier epithelial cells and the control of type 2 immunity. Immunity 43, 29-40. doi: 10.1016/j.immuni.2015.07.007
-
(2015)
Immunity
, vol.43
, pp. 29-40
-
-
Hammad, H.1
Lambrecht, B.N.2
-
54
-
-
84860785529
-
Molecular mechanism of ATP binding and ion channel activation in P2X receptors
-
Hattori, M., and Gouaux, E. (2012). Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature 485, 207-212. doi: 10.1038/nature11010
-
(2012)
Nature
, vol.485
, pp. 207-212
-
-
Hattori, M.1
Gouaux, E.2
-
55
-
-
0022596285
-
Intracellular epidermal interleukin 1-like factors in the human epidermoid carcinoma cell line A431
-
Hauser, C., Dayer, J. M., Jaunin, F., de Rochemonteix, B., and Saurat, J. H. (1986). Intracellular epidermal interleukin 1-like factors in the human epidermoid carcinoma cell line A431. Cell Immunol. 100, 89-96. doi: 10.1016/0008-8749(86)90009-2
-
(1986)
Cell Immunol
, vol.100
, pp. 89-96
-
-
Hauser, C.1
Dayer, J.M.2
Jaunin, F.3
de Rochemonteix, B.4
Saurat, J.H.5
-
56
-
-
84949091051
-
Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion
-
He, W. T., Wan, H., Hu, L., Chen, P., Wang, X., Huang, Z., et al. (2015). Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion. Cell Res. 25, 1285-1298. doi: 10.1038/cr.2015.139
-
(2015)
Cell Res
, vol.25
, pp. 1285-1298
-
-
He, W.T.1
Wan, H.2
Hu, L.3
Chen, P.4
Wang, X.5
Huang, Z.6
-
57
-
-
84995751273
-
Mechanism and regulation of NLRP3 inflammasome activation
-
He, Y., Hara, H., and Nunez, G. (2016a). Mechanism and regulation of NLRP3 inflammasome activation. Trends Biochem. Sci. 41, 1012-1021. doi: 10.1016/j.tibs.2016.09.002
-
(2016)
Trends Biochem. Sci
, vol.41
, pp. 1012-1021
-
-
He, Y.1
Hara, H.2
Nunez, G.3
-
58
-
-
84958971929
-
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
-
He, Y., Zeng, M. Y., Yang, D., Motro, B., and Nunez, G. (2016b). NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature 530, 354-357. doi: 10.1038/nature16959
-
(2016)
Nature
, vol.530
, pp. 354-357
-
-
He, Y.1
Zeng, M.Y.2
Yang, D.3
Motro, B.4
Nunez, G.5
-
59
-
-
84887446052
-
Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation
-
Heid, M. E., Keyel, P. A., Kamga, C., Shiva, S., Watkins, S. C., and Salter, R. D. (2013). Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J. Immunol. 191, 5230-5238. doi: 10.4049/jimmunol.1301490
-
(2013)
J. Immunol
, vol.191
, pp. 5230-5238
-
-
Heid, M.E.1
Keyel, P.A.2
Kamga, C.3
Shiva, S.4
Watkins, S.C.5
Salter, R.D.6
-
60
-
-
0026048272
-
Interleukin 1 is processed and released during apoptosis
-
Hogquist, K. A., Nett, M. A., Unanue, E. R., and Chaplin, D. D. (1991). Interleukin 1 is processed and released during apoptosis. Proc. Natl. Acad. Sci. U.S.A. 88, 8485-8489. doi: 10.1073/pnas.88.19.8485
-
(1991)
Proc. Natl. Acad. Sci. U.S.A
, vol.88
, pp. 8485-8489
-
-
Hogquist, K.A.1
Nett, M.A.2
Unanue, E.R.3
Chaplin, D.D.4
-
61
-
-
84900530332
-
Nucleotide signalling during inflammation
-
Idzko, M., Ferrari, D., and Eltzschig, H. K. (2014). Nucleotide signalling during inflammation. Nature 509, 310-317. doi: 10.1038/nature13085
-
(2014)
Nature
, vol.509
, pp. 310-317
-
-
Idzko, M.1
Ferrari, D.2
Eltzschig, H.K.3
-
62
-
-
84951309922
-
Medicinal chemistry of adenosine, P2Y and P2X receptors
-
Jacobson, K. A., and Muller, C. E. (2016). Medicinal chemistry of adenosine, P2Y and P2X receptors. Neuropharmacology 104, 31-49. doi: 10.1016/j.neuropharm.2015.12.001
-
(2016)
Neuropharmacology
, vol.104
, pp. 31-49
-
-
Jacobson, K.A.1
Muller, C.E.2
-
63
-
-
0035912764
-
How the immune system works to protect the host from infection: a personal view
-
Janeway, C. A. Jr. (2001). How the immune system works to protect the host from infection: a personal view. Proc. Natl. Acad. Sci. U.S.A. 98, 7461-7468. doi: 10.1073/pnas.131202998
-
(2001)
Proc. Natl. Acad. Sci. U.S.A
, vol.98
, pp. 7461-7468
-
-
Janeway, C.A.1
-
64
-
-
84881489108
-
Insights into the molecular mechanisms underlying Mammalian P2X7 receptor functions and contributions in diseases, revealed by structural modeling and single nucleotide polymorphisms
-
Jiang, L. H., Baldwin, J. M., Roger, S., and Baldwin, S. A. (2013). Insights into the molecular mechanisms underlying Mammalian P2X7 receptor functions and contributions in diseases, revealed by structural modeling and single nucleotide polymorphisms. Front. Pharmacol. 4:55. doi: 10.3389/fphar.2013.00055
-
(2013)
Front. Pharmacol
, vol.4
, pp. 55
-
-
Jiang, L.H.1
Baldwin, J.M.2
Roger, S.3
Baldwin, S.A.4
-
65
-
-
73249144903
-
Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta
-
Joosten, L. A., Netea, M. G., Fantuzzi, G., Koenders, M. I., Helsen, M. M., Sparrer, H., et al. (2009). Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 60, 3651-3662. doi: 10.1002/art.25006
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3651-3662
-
-
Joosten, L.A.1
Netea, M.G.2
Fantuzzi, G.3
Koenders, M.I.4
Helsen, M.M.5
Sparrer, H.6
-
66
-
-
79952192382
-
Immune cell regulation by autocrine purinergic signalling
-
Junger, W. G. (2011). Immune cell regulation by autocrine purinergic signalling. Nat. Rev. Immunol. 11, 201-212. doi: 10.1038/nri2938
-
(2011)
Nat. Rev. Immunol
, vol.11
, pp. 201-212
-
-
Junger, W.G.1
-
67
-
-
0015742688
-
Sources of leukocytic endogenous mediator in the rat
-
Kampschmidt, R. F., Pulliam, L. A., and Upchurch, H. F. (1973). Sources of leukocytic endogenous mediator in the rat. Proc. Soc. Exp. Biol. Med. 144, 882-886. doi: 10.3181/00379727-144-37703
-
(1973)
Proc. Soc. Exp. Biol. Med
, vol.144
, pp. 882-886
-
-
Kampschmidt, R.F.1
Pulliam, L.A.2
Upchurch, H.F.3
-
68
-
-
85006870202
-
Structural basis for subtype-specific inhibition of the P2X7 receptor
-
Karasawa, A., and Kawate, T. (2016). Structural basis for subtype-specific inhibition of the P2X7 receptor. Elife 5:e22153. doi: 10.7554/eLife.22153
-
(2016)
Elife
, vol.5
-
-
Karasawa, A.1
Kawate, T.2
-
69
-
-
84958230881
-
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1beta secretion in response to ATP
-
Karmakar, M., Katsnelson, M. A., Dubyak, G. R., and Pearlman, E. (2016). Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1beta secretion in response to ATP. Nat. Commun. 7:10555. doi: 10.1038/ncomms10555
-
(2016)
Nat. Commun
, vol.7
, pp. 10555
-
-
Karmakar, M.1
Katsnelson, M.A.2
Dubyak, G.R.3
Pearlman, E.4
-
70
-
-
84927669849
-
K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling
-
Katsnelson, M. A., Rucker, L. G., Russo, H. M., and Dubyak, G. R. (2015). K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling. J. Immunol. 194, 3937-3952. doi: 10.4049/jimmunol.1402658
-
(2015)
J. Immunol
, vol.194
, pp. 3937-3952
-
-
Katsnelson, M.A.1
Rucker, L.G.2
Russo, H.M.3
Dubyak, G.R.4
-
71
-
-
67949117176
-
Crystal structure of the ATP-gated P2X(4) ion channel in the closed state
-
Kawate, T., Michel, J. C., Birdsong, W. T., and Gouaux, E. (2009). Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature 460, 592-598. doi: 10.1038/nature08198
-
(2009)
Nature
, vol.460
, pp. 592-598
-
-
Kawate, T.1
Michel, J.C.2
Birdsong, W.T.3
Gouaux, E.4
-
72
-
-
84942856523
-
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
-
Kayagaki, N., Stowe, I. B., Lee, B. L., O'Rourke, K., Anderson, K., Warming, S., et al. (2015). Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 526, 666-671. doi: 10.1038/nature15541
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
Stowe, I.B.2
Lee, B.L.3
O'Rourke, K.4
Anderson, K.5
Warming, S.6
-
73
-
-
84923247523
-
Consensus guidelines for the detection of immunogenic cell death
-
Kepp, O., Senovilla, L., Vitale, I., Vacchelli, E., Adjemian, S., Agostinis, P., et al. (2014). Consensus guidelines for the detection of immunogenic cell death. Oncoimmunology 3:e955691. doi: 10.4161/21624011.2014.955691
-
(2014)
Oncoimmunology
, vol.3
-
-
Kepp, O.1
Senovilla, L.2
Vitale, I.3
Vacchelli, E.4
Adjemian, S.5
Agostinis, P.6
-
74
-
-
84949741912
-
NOD-like receptors in infection, immunity, and diseases
-
Kim, Y. K., Shin, J. S., and Nahm, M. H. (2016). NOD-like receptors in infection, immunity, and diseases. Yonsei Med. J. 57, 5-14. doi: 10.3349/ymj.2016.57.1.5
-
(2016)
Yonsei Med. J
, vol.57
, pp. 5-14
-
-
Kim, Y.K.1
Shin, J.S.2
Nahm, M.H.3
-
75
-
-
0021745716
-
Cloning and expression of murine interleukin-1 cDNA in Escherichia coli
-
Lomedico, P. T., Gubler, U., Hellmann, C. P., Dukovich, M., Giri, J. G., Pan, Y. C., et al. (1984). Cloning and expression of murine interleukin-1 cDNA in Escherichia coli. Nature 312, 458-462. doi: 10.1038/312458a0
-
(1984)
Nature
, vol.312
, pp. 458-462
-
-
Lomedico, P.T.1
Gubler, U.2
Hellmann, C.P.3
Dukovich, M.4
Giri, J.G.5
Pan, Y.C.6
-
76
-
-
0035655395
-
Rapid secretion of interleukin-1beta by microvesicle shedding
-
MacKenzie, A., Wilson, H. L., Kiss-Toth, E., Dower, S. K., North, R. A., and Surprenant, A. (2001). Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity 15, 825-835. doi: 10.1016/S1074-7613(01)00229-1
-
(2001)
Immunity
, vol.15
, pp. 825-835
-
-
MacKenzie, A.1
Wilson, H.L.2
Kiss-Toth, E.3
Dower, S.K.4
North, R.A.5
Surprenant, A.6
-
77
-
-
84990236600
-
X-ray structures define human P2X3 receptor gating cycle and antagonist action
-
Mansoor, S. E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., and Gouaux, E. (2016). X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature 538, 66-71. doi: 10.1038/nature19367
-
(2016)
Nature
, vol.538
, pp. 66-71
-
-
Mansoor, S.E.1
Lu, W.2
Oosterheert, W.3
Shekhar, M.4
Tajkhorshid, E.5
Gouaux, E.6
-
78
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., et al. (2004). Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430, 213-218. doi: 10.1038/nature02664
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
79
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., et al. (2006). Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232. doi: 10.1038/nature04515
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
80
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon, F., Burns, K., and Tschopp, J. (2002). The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell. 10, 417-426. doi: 10.1016/S1097-2765(02)00599-3
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
81
-
-
84957922975
-
Inflammasome-dependent IL-1beta release depends upon membrane permeabilisation
-
Martin-Sanchez, F., Diamond, C., Zeitler, M., Gomez, A. I., Baroja-Mazo, A., Bagnall, J., et al. (2016). Inflammasome-dependent IL-1beta release depends upon membrane permeabilisation. Cell Death Differ. 23, 1219-1231. doi: 10.1038/cdd.2015.176
-
(2016)
Cell Death Differ
, vol.23
, pp. 1219-1231
-
-
Martin-Sanchez, F.1
Diamond, C.2
Zeitler, M.3
Gomez, A.I.4
Baroja-Mazo, A.5
Bagnall, J.6
-
82
-
-
37049198188
-
Studies on the isolation of the factor responsible for tissue injury in inflammation
-
Menkin, V. (1943). Studies on the isolation of the factor responsible for tissue injury in inflammation. Science 97, 165-167. doi: 10.1126/science.97.2511.165
-
(1943)
Science
, vol.97
, pp. 165-167
-
-
Menkin, V.1
-
83
-
-
84879577117
-
Human astrocytes express a novel NLRP2 inflammasome
-
Minkiewicz, J., de Rivero Vaccari, J. P., and Keane, R. W. (2013). Human astrocytes express a novel NLRP2 inflammasome. Glia 61, 1113-1121. doi: 10.1002/glia.22499
-
(2013)
Glia
, vol.61
, pp. 1113-1121
-
-
Minkiewicz, J.1
de Rivero Vaccari, J.P.2
Keane, R.W.3
-
84
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Munoz-Planillo, R., Kuffa, P., Martinez-Colon, G., Smith, B. L., Rajendiran, T. M., and Nunez, G. (2013). K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 38, 1142-1153. doi: 10.1016/j.immuni.2013.05.016
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
85
-
-
0027530024
-
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor
-
Murgia, M., Hanau, S., Pizzo, P., Rippa, M., and Di Virgilio, F. (1993). Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor. J. Biol. Chem. 268, 8199-8203.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 8199-8203
-
-
Murgia, M.1
Hanau, S.2
Pizzo, P.3
Rippa, M.4
Di Virgilio, F.5
-
86
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K., Haspel, J. A., Rathinam, V. A., Lee, S. J., Dolinay, T., Lam, H. C., et al. (2011). Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 12, 222-230. doi: 10.1038/ni.1980
-
(2011)
Nat. Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
87
-
-
84963830347
-
Alarmins and antitumor immunity
-
Nie, Y., Yang, D., and Oppenheim, J. J. (2016). Alarmins and antitumor immunity. Clin. Ther. 38, 1042-1053. doi: 10.1016/j.clinthera.2016.03.021
-
(2016)
Clin. Ther
, vol.38
, pp. 1042-1053
-
-
Nie, Y.1
Yang, D.2
Oppenheim, J.J.3
-
89
-
-
33747191203
-
The inflammasome: first line of the immune response to cell stress
-
Ogura, Y., Sutterwala, F. S., and Flavell, R. A. (2006). The inflammasome: first line of the immune response to cell stress. Cell 126, 659-662. doi: 10.1016/j.cell.2006.08.002
-
(2006)
Cell
, vol.126
, pp. 659-662
-
-
Ogura, Y.1
Sutterwala, F.S.2
Flavell, R.A.3
-
90
-
-
47249144272
-
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage
-
Pelegrin, P., Barroso-Gutierrez, C., and Surprenant, A. (2008). P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J. Immunol. 180, 7147-7157. doi: 10.4049/jimmunol.180.11.7147
-
(2008)
J. Immunol
, vol.180
, pp. 7147-7157
-
-
Pelegrin, P.1
Barroso-Gutierrez, C.2
Surprenant, A.3
-
91
-
-
34047270416
-
Pannexin-1 couples to maitotoxin-and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway
-
Pelegrin, P., and Surprenant, A. (2007). Pannexin-1 couples to maitotoxin-and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway. J. Biol. Chem. 282, 2386-2394. doi: 10.1074/jbc.M610351200
-
(2007)
J. Biol. Chem
, vol.282
, pp. 2386-2394
-
-
Pelegrin, P.1
Surprenant, A.2
-
92
-
-
23044473247
-
A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion
-
Pellegatti, P., Falzoni, S., Pinton, P., Rizzuto, R., and Di Virgilio, F. (2005). A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. Mol. Biol. Cell 16, 3659-3665. doi: 10.1091/mbc.E05-03-0222
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3659-3665
-
-
Pellegatti, P.1
Falzoni, S.2
Pinton, P.3
Rizzuto, R.4
Di Virgilio, F.5
-
93
-
-
0026751492
-
IL-1 beta maturation: evidence that mature cytokine formation can be induced specifically by nigericin
-
Perregaux, D., Barberia, J., Lanzetti, A. J., Geoghegan, K. F., Carty, T. J., and Gabel, C. A. (1992). IL-1 beta maturation: evidence that mature cytokine formation can be induced specifically by nigericin. J. Immunol. 149, 1294-1303.
-
(1992)
J. Immunol
, vol.149
, pp. 1294-1303
-
-
Perregaux, D.1
Barberia, J.2
Lanzetti, A.J.3
Geoghegan, K.F.4
Carty, T.J.5
Gabel, C.A.6
-
94
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux, D., and Gabel, C. A. (1994). Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269, 15195-15203.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
95
-
-
34247353273
-
Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells
-
Pizzirani, C., Ferrari, D., Chiozzi, P., Adinolfi, E., Sandona, D., Savaglio, E., et al. (2007). Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells. Blood 109, 3856-3864. doi: 10.1182/blood-2005-06-031377
-
(2007)
Blood
, vol.109
, pp. 3856-3864
-
-
Pizzirani, C.1
Ferrari, D.2
Chiozzi, P.3
Adinolfi, E.4
Sandona, D.5
Savaglio, E.6
-
96
-
-
85010916994
-
Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation
-
Prochnicki, T., Mangan, M. S., and Latz, E. (2016). Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation. F1000Res 5:F1000. doi: 10.12688/f1000research.8614.1
-
(2016)
F1000Res
, vol.5
, pp. F1000
-
-
Prochnicki, T.1
Mangan, M.S.2
Latz, E.3
-
97
-
-
34548614009
-
Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
-
Qu, Y., Franchi, L., Nunez, G., and Dubyak, G. R. (2007). Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J. Immunol. 179, 1913-1925. doi: 10.4049/jimmunol.179.3.1913
-
(2007)
J. Immunol
, vol.179
, pp. 1913-1925
-
-
Qu, Y.1
Franchi, L.2
Nunez, G.3
Dubyak, G.R.4
-
98
-
-
65249164404
-
P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1
-
Qu, Y., Ramachandra, L., Mohr, S., Franchi, L., Harding, C. V., Nunez, G., et al. (2009). P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1. J. Immunol. 182, 5052-5062. doi: 10.4049/jimmunol.0802968
-
(2009)
J. Immunol
, vol.182
, pp. 5052-5062
-
-
Qu, Y.1
Ramachandra, L.2
Mohr, S.3
Franchi, L.4
Harding, C.V.5
Nunez, G.6
-
99
-
-
84939889550
-
NLRP3 inflammasome activation and interleukin-1beta release in macrophages require calcium but are independent of calcium-activated NADPH oxidases
-
Rada, B., Park, J. J., Sil, P., Geiszt, M., and Leto, T. L. (2014). NLRP3 inflammasome activation and interleukin-1beta release in macrophages require calcium but are independent of calcium-activated NADPH oxidases. Inflamm. Res. 63, 821-830. doi: 10.1007/s00011-014-0756-y
-
(2014)
Inflamm. Res
, vol.63
, pp. 821-830
-
-
Rada, B.1
Park, J.J.2
Sil, P.3
Geiszt, M.4
Leto, T.L.5
-
100
-
-
78649956456
-
Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation
-
Ramachandra, L., Qu, Y., Wang, Y., Lewis, C. J., Cobb, B. A., Takatsu, K., et al. (2010). Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation. Infect. Immun. 78, 5116-5125. doi: 10.1128/IAI.01089-09
-
(2010)
Infect. Immun
, vol.78
, pp. 5116-5125
-
-
Ramachandra, L.1
Qu, Y.2
Wang, Y.3
Lewis, C.J.4
Cobb, B.A.5
Takatsu, K.6
-
101
-
-
84965107840
-
Inflammasome complexes: emerging mechanisms and effector functions
-
Rathinam, V. A., and Fitzgerald, K. A. (2016). Inflammasome complexes: emerging mechanisms and effector functions. Cell 165, 792-800. doi: 10.1016/j.cell.2016.03.046
-
(2016)
Cell
, vol.165
, pp. 792-800
-
-
Rathinam, V.A.1
Fitzgerald, K.A.2
-
102
-
-
0025255629
-
A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence
-
Rubartelli, A., Cozzolino, F., Talio, M., and Sitia, R. (1990). A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence. EMBO J. 9, 1503-1510.
-
(1990)
EMBO J
, vol.9
, pp. 1503-1510
-
-
Rubartelli, A.1
Cozzolino, F.2
Talio, M.3
Sitia, R.4
-
103
-
-
85018192984
-
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death
-
Salaro, E., Rambaldi, A., Falzoni, S., Amoroso, F. S., Franceschini, A., Sarti, A. C., et al. (2016). Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death. Sci. Rep. 6:26280. doi: 10.1038/srep26280
-
(2016)
Sci. Rep
, vol.6
, pp. 26280
-
-
Salaro, E.1
Rambaldi, A.2
Falzoni, S.3
Amoroso, F.S.4
Franceschini, A.5
Sarti, A.C.6
-
104
-
-
84978767585
-
Bifunctional probes of cathepsin protease activity and pH reveal alterations in endolysosomal pH during bacterial infection
-
Sanman, L. E., van der Linden, W. A., Verdoes, M., and Bogyo, M. (2016). Bifunctional probes of cathepsin protease activity and pH reveal alterations in endolysosomal pH during bacterial infection. Cell Chem. Biol. 23, 793-804. doi: 10.1016/j.chembiol.2016.05.019
-
(2016)
Cell Chem. Biol
, vol.23
, pp. 793-804
-
-
Sanman, L.E.1
van der Linden, W.A.2
Verdoes, M.3
Bogyo, M.4
-
105
-
-
64249169414
-
Activation of microglia by amyloid (beta) requires P2X7 receptor expression
-
Sanz, J. M., Chiozzi, P., Ferrari, D., Colaianna, M., Idzko, M., Falzoni, S., et al. (2009). Activation of microglia by amyloid (beta) requires P2X7 receptor expression. J. Immunol. 182, 4378-4385. doi: 10.4049/jimmunol.0803612
-
(2009)
J. Immunol
, vol.182
, pp. 4378-4385
-
-
Sanz, J.M.1
Chiozzi, P.2
Ferrari, D.3
Colaianna, M.4
Idzko, M.5
Falzoni, S.6
-
106
-
-
77950362382
-
The inflammasomes
-
Schroder, K., and Tschopp, J. (2010). The inflammasomes. Cell 140, 821-832. doi: 10.1016/j.cell.2010.01.040
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
107
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., et al. (2015). Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526, 660-665. doi: 10.1038/nature15514
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
Shi, X.4
Wang, Y.5
Huang, H.6
-
108
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi, J., Zhao, Y., Wang, Y., Gao, W., Ding, J., Li, P., et al. (2014). Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 514, 187-192. doi: 10.1038/nature13683
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
-
109
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada, K., Crother, T. R., Karlin, J., Dagvadorj, J., Chiba, N., Chen, S., et al. (2012). Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 36, 401-414. doi: 10.1016/j.immuni.2012.01.009
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
-
110
-
-
0021286985
-
Pharmacological evidence that adenosine triphosphate and noradrenaline are co-transmitters in the guinea-pig vas deferens
-
Sneddon, P., and Westfall, D. P. (1984). Pharmacological evidence that adenosine triphosphate and noradrenaline are co-transmitters in the guinea-pig vas deferens. J. Physiol. 347, 561-580. doi: 10.1113/jphysiol.1984.sp015083
-
(1984)
J. Physiol
, vol.347
, pp. 561-580
-
-
Sneddon, P.1
Westfall, D.P.2
-
111
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle, M., Labasi, J., Perregaux, D. G., Stam, E., Petrushova, N., Koller, B. H., et al. (2001). Altered cytokine production in mice lacking P2X(7) receptors. J. Biol. Chem. 276, 125-132. doi: 10.1074/jbc.M006781200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
-
112
-
-
32544448639
-
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling
-
Suadicani, S. O., Brosnan, C. F., and Scemes, E. (2006). P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J. Neurosci. 26, 1378-1385. doi: 10.1523/JNEUROSCI.3902-05.2006
-
(2006)
J. Neurosci
, vol.26
, pp. 1378-1385
-
-
Suadicani, S.O.1
Brosnan, C.F.2
Scemes, E.3
-
113
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
Surprenant, A., Rassendren, F., Kawashima, E., North, R. A., and Buell, G. (1996). The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272, 735-738. doi: 10.1126/science.272.5262.735
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
North, R.A.4
Buell, G.5
-
114
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry, N. A., Bull, H. G., Calaycay, J. R., Chapman, K. T., Howard, A. D., Kostura, M. J., et al. (1992). A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356, 768-774. doi: 10.1038/356768a0
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
-
115
-
-
84866425004
-
Microglial microvesicle secretion and intercellular signaling
-
Turola, E., Furlan, R., Bianco, F., Matteoli, M., and Verderio, C. (2012). Microglial microvesicle secretion and intercellular signaling. Front. Physiol. 3:149. doi: 10.3389/fphys.2012.00149
-
(2012)
Front. Physiol
, vol.3
, pp. 149
-
-
Turola, E.1
Furlan, R.2
Bianco, F.3
Matteoli, M.4
Verderio, C.5
-
116
-
-
84941284605
-
DAMPs from cell death to new life
-
Venereau, E., Ceriotti, C., and Bianchi, M. E. (2015). DAMPs from cell death to new life. Front. Immunol. 6:422. doi: 10.3389/fimmu.2015.00422
-
(2015)
Front. Immunol
, vol.6
, pp. 422
-
-
Venereau, E.1
Ceriotti, C.2
Bianchi, M.E.3
-
117
-
-
84866343704
-
Myeloid microvesicles are a marker and therapeutic target for neuroinflammation
-
Verderio, C., Muzio, L., Turola, E., Bergami, A., Novellino, L., Ruffini, F., et al. (2012). Myeloid microvesicles are a marker and therapeutic target for neuroinflammation. Ann. Neurol. 72, 610-624. doi: 10.1002/ana.23627
-
(2012)
Ann. Neurol
, vol.72
, pp. 610-624
-
-
Verderio, C.1
Muzio, L.2
Turola, E.3
Bergami, A.4
Novellino, L.5
Ruffini, F.6
-
118
-
-
84945542875
-
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
-
Vigano, E., Diamond, C. E., Spreafico, R., Balachander, A., Sobota, R. M., and Mortellaro, A. (2015). Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes. Nat. Commun. 6:8761. doi: 10.1038/ncomms9761
-
(2015)
Nat. Commun
, vol.6
, pp. 8761
-
-
Vigano, E.1
Diamond, C.E.2
Spreafico, R.3
Balachander, A.4
Sobota, R.M.5
Mortellaro, A.6
-
119
-
-
84962861111
-
The intersection of cell death and inflammasome activation
-
Vince, J. E., and Silke, J. (2016). The intersection of cell death and inflammasome activation. Cell Mol. Life Sci. 73, 2349-2367. doi: 10.1007/s00018-016-2205-2
-
(2016)
Cell Mol. Life Sci
, vol.73
, pp. 2349-2367
-
-
Vince, J.E.1
Silke, J.2
-
120
-
-
0028989337
-
Potassium-inhibited processing of IL-1 beta in human monocytes
-
Walev, I., Reske, K., Palmer, M., Valeva, A., and Bhakdi, S. (1995). Potassium-inhibited processing of IL-1 beta in human monocytes. EMBO J. 14, 1607-1614.
-
(1995)
EMBO J
, vol.14
, pp. 1607-1614
-
-
Walev, I.1
Reske, K.2
Palmer, M.3
Valeva, A.4
Bhakdi, S.5
-
121
-
-
84885615786
-
Autophagy-dependent ATP release from dying cells via lysosomal exocytosis
-
Wang, Y., Martins, I., Ma, Y., Kepp, O., Galluzzi, L., and Kroemer, G. (2013). Autophagy-dependent ATP release from dying cells via lysosomal exocytosis. Autophagy 9, 1624-1625. doi: 10.4161/auto.25873
-
(2013)
Autophagy
, vol.9
, pp. 1624-1625
-
-
Wang, Y.1
Martins, I.2
Ma, Y.3
Kepp, O.4
Galluzzi, L.5
Kroemer, G.6
-
122
-
-
3142660196
-
IL-1beta: an endosomal exit
-
Wewers, M. D. (2004). IL-1beta: an endosomal exit. Proc. Natl. Acad. Sci. U.S.A. 101, 10241-10242. doi: 10.1073/pnas.0403971101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 10241-10242
-
-
Wewers, M.D.1
-
123
-
-
84947441282
-
Caspase-11 requires the pannexin-1 channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock
-
Yang, D., He, Y., Munoz-Planillo, R., Liu, Q., and Nunez, G. (2015). Caspase-11 requires the pannexin-1 channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock. Immunity 43, 923-932. doi: 10.1016/j.immuni.2015.10.009
-
(2015)
Immunity
, vol.43
, pp. 923-932
-
-
Yang, D.1
He, Y.2
Munoz-Planillo, R.3
Liu, Q.4
Nunez, G.5
-
124
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R., Yazdi, A. S., Menu, P., and Tschopp, J. (2011). A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225. doi: 10.1038/nature09663
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
|