메뉴 건너뛰기




Volumn 6, Issue AUG, 2015, Pages

DAMPs from cell death to new life

Author keywords

ATP; DAMP; HMGB1; Inflammation; Tissue repair

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHEMOKINE RECEPTOR CXCR4; CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 8; PURINERGIC P2X RECEPTOR; PURINERGIC P2X7 RECEPTOR; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84941284605     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00422     Document Type: Review
Times cited : (494)

References (112)
  • 1
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway CA. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol (1989) 54(Pt 1):1-13. doi:10.1101/SQB.1989.054.01.003.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 2
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol (1994) 12:991-1045. doi:10.1146/annurev.iy.12.040194.005015.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 3
    • 0027979555 scopus 로고
    • The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants
    • Land W, Schneeberger H, Schleibner S, Illner WD, Abendroth D, Rutili G, et al. The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants. Transplantation (1994) 57:211-7. doi:10.1097/00007890-199401001-00010.
    • (1994) Transplantation , vol.57 , pp. 211-217
    • Land, W.1    Schneeberger, H.2    Schleibner, S.3    Illner, W.D.4    Abendroth, D.5    Rutili, G.6
  • 4
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature (2002) 418:191-5. doi:10.1038/nature00858.
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 5
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature (2003) 425:516-21. doi:10.1038/nature01991.
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 6
    • 84919346965 scopus 로고    scopus 로고
    • Complexity of danger: the diverse nature of damage-associated molecular patterns
    • Schaefer L. Complexity of danger: the diverse nature of damage-associated molecular patterns. J Biol Chem (2014) 289:35237-45. doi:10.1074/jbc. R114.619304.
    • (2014) J Biol Chem , vol.289 , pp. 35237-35245
    • Schaefer, L.1
  • 7
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol (2007) 81:1-5. doi:10.1189/jlb.0306164.
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 8
    • 84870487825 scopus 로고    scopus 로고
    • Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis
    • Lopetuso LR, Scaldaferri F, Pizarro TT. Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis. Fibrogenesis Tissue Repair (2012) 5:18. doi:10.1186/1755-1536-5-18.
    • (2012) Fibrogenesis Tissue Repair , vol.5 , pp. 18
    • Lopetuso, L.R.1    Scaldaferri, F.2    Pizarro, T.T.3
  • 9
    • 84900530332 scopus 로고    scopus 로고
    • Nucleotide signalling during inflammation
    • Idzko M, Ferrari D, Eltzschig HK. Nucleotide signalling during inflammation. Nature (2014) 509:310-7. doi:10.1038/nature13085.
    • (2014) Nature , vol.509 , pp. 310-317
    • Idzko, M.1    Ferrari, D.2    Eltzschig, H.K.3
  • 11
    • 79953068336 scopus 로고    scopus 로고
    • Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation
    • Krysko DV, Agostinis P, Krysko O, Garg AD, Bachert C, Lambrecht BN, et al. Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation. Trends Immunol (2011) 32:157-64. doi:10.1016/j.it.2011.01.005.
    • (2011) Trends Immunol , vol.32 , pp. 157-164
    • Krysko, D.V.1    Agostinis, P.2    Krysko, O.3    Garg, A.D.4    Bachert, C.5    Lambrecht, B.N.6
  • 12
    • 0033538467 scopus 로고    scopus 로고
    • HMG-1 as a late mediator of endotoxin lethality in mice
    • Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science (1999) 285:248-51. doi:10.1126/science.285.5425.248.
    • (1999) Science , vol.285 , pp. 248-251
    • Wang, H.1    Bloom, O.2    Zhang, M.3    Vishnubhakat, J.M.4    Ombrellino, M.5    Che, J.6
  • 13
    • 0036775236 scopus 로고    scopus 로고
    • The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
    • Gardella S, Andrei C, Ferrera D, Lotti LV, Torrisi MR, Bianchi ME, et al. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep (2002) 3:995-1001. doi:10.1093/embo-reports/kvf198.
    • (2002) EMBO Rep , vol.3 , pp. 995-1001
    • Gardella, S.1    Andrei, C.2    Ferrera, D.3    Lotti, L.V.4    Torrisi, M.R.5    Bianchi, M.E.6
  • 14
    • 43049105018 scopus 로고    scopus 로고
    • Neutrophils as sources of extracellular nucleotides: functional consequences at the vascular interface
    • Eltzschig HK, Macmanus CF, Colgan SP. Neutrophils as sources of extracellular nucleotides: functional consequences at the vascular interface. Trends Cardiovasc Med (2008) 18:103-7. doi:10.1016/j.tcm.2008.01.006.
    • (2008) Trends Cardiovasc Med , vol.18 , pp. 103-107
    • Eltzschig, H.K.1    Macmanus, C.F.2    Colgan, S.P.3
  • 15
    • 26844468253 scopus 로고    scopus 로고
    • Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
    • Gardai SJ, McPhillips KA, Frasch SC, Janssen WJ, Starefeldt A, Murphy-Ullrich JE, et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell (2005) 123:321-34. doi:10.1016/j.cell.2005.08.032.
    • (2005) Cell , vol.123 , pp. 321-334
    • Gardai, S.J.1    McPhillips, K.A.2    Frasch, S.C.3    Janssen, W.J.4    Starefeldt, A.5    Murphy-Ullrich, J.E.6
  • 16
    • 24344498241 scopus 로고    scopus 로고
    • HMG proteins: dynamic players in gene regulation and differentiation
    • Bianchi ME, Agresti A. HMG proteins: dynamic players in gene regulation and differentiation. Curr Opin Genet Dev (2005) 15:496-506. doi:10.1016/j.gde.2005.08.007.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 496-506
    • Bianchi, M.E.1    Agresti, A.2
  • 17
    • 84901010218 scopus 로고    scopus 로고
    • Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review
    • Lu B, Wang C, Wang M, Li W, Chen F, Tracey KJ, et al. Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review. Expert Rev Clin Immunol (2014) 10:713-27. doi:10.1586/1744666X.2014.909730.
    • (2014) Expert Rev Clin Immunol , vol.10 , pp. 713-727
    • Lu, B.1    Wang, C.2    Wang, M.3    Li, W.4    Chen, F.5    Tracey, K.J.6
  • 18
    • 0142137129 scopus 로고    scopus 로고
    • Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
    • Bonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, Bachi A, et al. Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J (2003) 22:5551-60. doi:10.1093/emboj/cdg516.
    • (2003) EMBO J , vol.22 , pp. 5551-5560
    • Bonaldi, T.1    Talamo, F.2    Scaffidi, P.3    Ferrera, D.4    Porto, A.5    Bachi, A.6
  • 19
    • 84862776783 scopus 로고    scopus 로고
    • Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity
    • Antoine DJ, Jenkins RE, Dear JW, Williams DP, McGill MR, Sharpe MR, et al. Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity. J Hepatol (2012) 56:1070-9. doi:10.1016/j.jhep.2011.12.019.
    • (2012) J Hepatol , vol.56 , pp. 1070-1079
    • Antoine, D.J.1    Jenkins, R.E.2    Dear, J.W.3    Williams, D.P.4    McGill, M.R.5    Sharpe, M.R.6
  • 20
    • 84874919170 scopus 로고    scopus 로고
    • Regulation of HMGB1 release by inflammasomes
    • Lu B, Wang H, Andersson U, Tracey KJ. Regulation of HMGB1 release by inflammasomes. Protein Cell (2013) 4:163-7. doi:10.1007/s13238-012-2118-2.
    • (2013) Protein Cell , vol.4 , pp. 163-167
    • Lu, B.1    Wang, H.2    Andersson, U.3    Tracey, K.J.4
  • 21
    • 84874280249 scopus 로고    scopus 로고
    • ATP release and purinergic signaling in NLRP3 inflammasome activation
    • Gombault A, Baron L, Couillin I. ATP release and purinergic signaling in NLRP3 inflammasome activation. Front Immunol (2013) 3:414. doi:10.3389/fimmu.2012.00414.
    • (2013) Front Immunol , vol.3 , pp. 414
    • Gombault, A.1    Baron, L.2    Couillin, I.3
  • 22
    • 84942983947 scopus 로고    scopus 로고
    • Stress sounds the alarmin: the role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming
    • Frank MG, Weber MD, Watkins LR, Maier SF. Stress sounds the alarmin: the role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming. Brain Behav Immun (2015) 48:1-7. doi:10.1016/j.bbi.2015.03.010.
    • (2015) Brain Behav Immun , vol.48 , pp. 1-7
    • Frank, M.G.1    Weber, M.D.2    Watkins, L.R.3    Maier, S.F.4
  • 23
    • 84983191497 scopus 로고    scopus 로고
    • Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis
    • Geng Y, Ma Q, Liu Y-N, Peng N, Yuan F-F, Li X-G, et al. Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis. J Hepatol (2015). doi:10.1016/j.jhep.2015.04.010.
    • (2015) J Hepatol
    • Geng, Y.1    Ma, Q.2    Liu, Y.-N.3    Peng, N.4    Yuan, F.-F.5    Li, X.-G.6
  • 24
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 is a therapeutic target for sterile inflammation and infection
    • Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol (2011) 29:139-62. doi:10.1146/annurev-immunol-030409-101323.
    • (2011) Annu Rev Immunol , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 25
    • 0027169842 scopus 로고
    • Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation
    • Parkkinen J, Raulo E, Merenmies J, Nolo R, Kajander EO, Baumann M, et al. Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation. J Biol Chem (1993) 268:19726-38.
    • (1993) J Biol Chem , vol.268 , pp. 19726-19738
    • Parkkinen, J.1    Raulo, E.2    Merenmies, J.3    Nolo, R.4    Kajander, E.O.5    Baumann, M.6
  • 26
    • 84879593735 scopus 로고    scopus 로고
    • RAGE regulation and signaling in inflammation and beyond
    • Kierdorf K, Fritz G. RAGE regulation and signaling in inflammation and beyond. J Leukoc Biol (2013) 94:55-68. doi:10.1189/jlb.1012519.
    • (2013) J Leukoc Biol , vol.94 , pp. 55-68
    • Kierdorf, K.1    Fritz, G.2
  • 27
    • 19944431800 scopus 로고    scopus 로고
    • RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages
    • Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger C-J, Arnold B, et al. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol (2005) 61:1-9. doi:10.1111/j.0300-9475.2005.01534.x.
    • (2005) Scand J Immunol , vol.61 , pp. 1-9
    • Kokkola, R.1    Andersson, A.2    Mullins, G.3    Ostberg, T.4    Treutiger, C.-J.5    Arnold, B.6
  • 28
    • 0037769813 scopus 로고    scopus 로고
    • Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells
    • Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, Shelhamer JH, et al. Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood (2003) 101:2652-60. doi:10.1182/blood-2002-05-1300.
    • (2003) Blood , vol.101 , pp. 2652-2660
    • Fiuza, C.1    Bustin, M.2    Talwar, S.3    Tropea, M.4    Gerstenberger, E.5    Shelhamer, J.H.6
  • 29
    • 84860361435 scopus 로고    scopus 로고
    • HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
    • Schiraldi M, Raucci A, Muñoz LM, Livoti E, Celona B, Venereau E, et al. HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. J Exp Med (2012) 209:551-63. doi:10.1084/jem.20111739.
    • (2012) J Exp Med , vol.209 , pp. 551-563
    • Schiraldi, M.1    Raucci, A.2    Muñoz, L.M.3    Livoti, E.4    Celona, B.5    Venereau, E.6
  • 30
    • 34247236200 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
    • Tian J, Avalos AM, Mao S-Y, Chen B, Senthil K, Wu H, et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol (2007) 8:487-96. doi:10.1038/ni1457.
    • (2007) Nat Immunol , vol.8 , pp. 487-496
    • Tian, J.1    Avalos, A.M.2    Mao, S.-Y.3    Chen, B.4    Senthil, K.5    Wu, H.6
  • 31
    • 59649126956 scopus 로고    scopus 로고
    • Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE
    • Urbonaviciute V, Fürnrohr BG, Meister S, Munoz L, Heyder P, De Marchis F, et al. Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE. J Exp Med (2008) 205:3007-18. doi:10.1084/jem.20081165.
    • (2008) J Exp Med , vol.205 , pp. 3007-3018
    • Urbonaviciute, V.1    Fürnrohr, B.G.2    Meister, S.3    Munoz, L.4    Heyder, P.5    De Marchis, F.6
  • 32
    • 84872162386 scopus 로고    scopus 로고
    • High-mobility group box 1 (HMGB1)-toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: interaction of γδ T cells with macrophages
    • Wang X, Sun R, Wei H, Tian Z. High-mobility group box 1 (HMGB1)-toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: interaction of γδ T cells with macrophages. Hepatology (2013) 57:373-84. doi:10.1002/hep.25982.
    • (2013) Hepatology , vol.57 , pp. 373-384
    • Wang, X.1    Sun, R.2    Wei, H.3    Tian, Z.4
  • 33
    • 84879655800 scopus 로고    scopus 로고
    • TLR4 as receptor for HMGB1-mediated acute lung injury after liver ischemia/reperfusion injury
    • Yang Z, Deng Y, Su D, Tian J, Gao Y, He Z, et al. TLR4 as receptor for HMGB1-mediated acute lung injury after liver ischemia/reperfusion injury. Lab Invest (2013) 93:792-800. doi:10.1038/labinvest.2013.66.
    • (2013) Lab Invest , vol.93 , pp. 792-800
    • Yang, Z.1    Deng, Y.2    Su, D.3    Tian, J.4    Gao, Y.5    He, Z.6
  • 34
    • 84879440776 scopus 로고    scopus 로고
    • Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors
    • Weng H, Deng Y, Xie Y, Liu H, Gong F. Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors. BMC Cancer (2013) 13:311. doi:10.1186/1471-2407-13-311.
    • (2013) BMC Cancer , vol.13 , pp. 311
    • Weng, H.1    Deng, Y.2    Xie, Y.3    Liu, H.4    Gong, F.5
  • 35
    • 77950539231 scopus 로고    scopus 로고
    • Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures
    • Maroso M, Balosso S, Ravizza T, Liu J, Aronica E, Iyer AM, et al. Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. Nat Med (2010) 16:413-9. doi:10.1038/nm.2127.
    • (2010) Nat Med , vol.16 , pp. 413-419
    • Maroso, M.1    Balosso, S.2    Ravizza, T.3    Liu, J.4    Aronica, E.5    Iyer, A.M.6
  • 36
    • 84898683559 scopus 로고    scopus 로고
    • A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins
    • Antoine DJ, Harris HE, Andersson U, Tracey KJ, Bianchi ME. A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins. Mol Med (2014) 20:135-7. doi:10.2119/molmed.2014.00022.
    • (2014) Mol Med , vol.20 , pp. 135-137
    • Antoine, D.J.1    Harris, H.E.2    Andersson, U.3    Tracey, K.J.4    Bianchi, M.E.5
  • 37
    • 84921328278 scopus 로고    scopus 로고
    • MD-2 is required for disulfide HMGB1-dependent TLR4 signaling
    • Yang H, Wang H, Ju Z, Ragab AA, Lundbäck P, Long W, et al. MD-2 is required for disulfide HMGB1-dependent TLR4 signaling. J Exp Med (2015) 212:5-14. doi:10.1084/jem.20141318.
    • (2015) J Exp Med , vol.212 , pp. 5-14
    • Yang, H.1    Wang, H.2    Ju, Z.3    Ragab, A.A.4    Lundbäck, P.5    Long, W.6
  • 38
    • 84866378556 scopus 로고    scopus 로고
    • Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
    • Venereau E, Casalgrandi M, Schiraldi M, Antoine DJ, Cattaneo A, De Marchis F, et al. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med (2012) 209:1519-28. doi:10.1084/jem.20120189.
    • (2012) J Exp Med , vol.209 , pp. 1519-1528
    • Venereau, E.1    Casalgrandi, M.2    Schiraldi, M.3    Antoine, D.J.4    Cattaneo, A.5    De Marchis, F.6
  • 39
    • 84920943309 scopus 로고    scopus 로고
    • DAMP signaling is a key pathway inducing immune modulation after brain injury
    • Liesz A, Dalpke A, Mracsko E, Antoine DJ, Roth S, Zhou W, et al. DAMP signaling is a key pathway inducing immune modulation after brain injury. J Neurosci (2015) 35:583-98. doi:10.1523/JNEUROSCI.2439-14.2015.
    • (2015) J Neurosci , vol.35 , pp. 583-598
    • Liesz, A.1    Dalpke, A.2    Mracsko, E.3    Antoine, D.J.4    Roth, S.5    Zhou, W.6
  • 40
    • 84859440796 scopus 로고    scopus 로고
    • HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease
    • Harris HE, Andersson U, Pisetsky DS. HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease. Nat Rev Rheumatol (2012) 8:195-202. doi:10.1038/nrrheum.2011.222.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 195-202
    • Harris, H.E.1    Andersson, U.2    Pisetsky, D.S.3
  • 41
    • 84966333750 scopus 로고    scopus 로고
    • Characterization of the inflammatory properties of actively released HMGB1 in juvenile idiopathic arthritis
    • Lundbäck P, Stridh P, Klevenvall L, Jenkins RE, Fischer M, Sundberg E, et al. Characterization of the inflammatory properties of actively released HMGB1 in juvenile idiopathic arthritis. Antioxid Redox Signal (2015). doi:10.1089/ars.2014.6039.
    • (2015) Antioxid Redox Signal
    • Lundbäck, P.1    Stridh, P.2    Klevenvall, L.3    Jenkins, R.E.4    Fischer, M.5    Sundberg, E.6
  • 42
    • 84926416315 scopus 로고    scopus 로고
    • Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis
    • Agalave NM, Larsson M, Abdelmoaty S, Su J, Baharpoor A, Lundbäck P, et al. Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis. Pain (2014) 155:1802-13. doi:10.1016/j.pain.2014.06.007.
    • (2014) Pain , vol.155 , pp. 1802-1813
    • Agalave, N.M.1    Larsson, M.2    Abdelmoaty, S.3    Su, J.4    Baharpoor, A.5    Lundbäck, P.6
  • 43
    • 84921902183 scopus 로고    scopus 로고
    • High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome
    • Palmblad K, Schierbeck H, Sundberg E, Horne A-C, Harris HE, Henter J-I, et al. High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome. Mol Med (2014) 20:538-47. doi:10.2119/molmed.2014.00183.
    • (2014) Mol Med , vol.20 , pp. 538-547
    • Palmblad, K.1    Schierbeck, H.2    Sundberg, E.3    Horne, A.-C.4    Harris, H.E.5    Henter, J.-I.6
  • 44
    • 84872842379 scopus 로고    scopus 로고
    • TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis
    • Nyström S, Antoine DJ, Lundbäck P, Lock JG, Nita AF, Högstrand K, et al. TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis. EMBO J (2013) 32:86-99. doi:10.1038/emboj.2012.328.
    • (2013) EMBO J , vol.32 , pp. 86-99
    • Nyström, S.1    Antoine, D.J.2    Lundbäck, P.3    Lock, J.G.4    Nita, A.F.5    Högstrand, K.6
  • 45
    • 0022629214 scopus 로고
    • Extracellular ATP: effects, sources and fate
    • Gordon JL. Extracellular ATP: effects, sources and fate. Biochem J (1986) 233:309-19.
    • (1986) Biochem J , vol.233 , pp. 309-319
    • Gordon, J.L.1
  • 46
    • 79952192382 scopus 로고    scopus 로고
    • Immune cell regulation by autocrine purinergic signalling
    • Junger WG. Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol (2011) 11:201-12. doi:10.1038/nri2938.
    • (2011) Nat Rev Immunol , vol.11 , pp. 201-212
    • Junger, W.G.1
  • 47
    • 84857997683 scopus 로고    scopus 로고
    • A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
    • Garg AD, Krysko DV, Verfaillie T, Kaczmarek A, Ferreira GB, Marysael T, et al. A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J (2012) 31:1062-79. doi:10.1038/emboj.2011.497.
    • (2012) EMBO J , vol.31 , pp. 1062-1079
    • Garg, A.D.1    Krysko, D.V.2    Verfaillie, T.3    Kaczmarek, A.4    Ferreira, G.B.5    Marysael, T.6
  • 48
    • 84871048026 scopus 로고    scopus 로고
    • Purinergic signaling during inflammation
    • Eltzschig HK, Sitkovsky MV, Robson SC. Purinergic signaling during inflammation. N Engl J Med (2012) 367:2322-33. doi:10.1056/NEJMra1205750.
    • (2012) N Engl J Med , vol.367 , pp. 2322-2333
    • Eltzschig, H.K.1    Sitkovsky, M.V.2    Robson, S.C.3
  • 49
    • 0025874599 scopus 로고
    • Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis
    • Knowles MR, Clarke LL, Boucher RC. Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis. N Engl J Med (1991) 325:533-8. doi:10.1056/NEJM199108223250802.
    • (1991) N Engl J Med , vol.325 , pp. 533-538
    • Knowles, M.R.1    Clarke, L.L.2    Boucher, R.C.3
  • 50
    • 70249090374 scopus 로고    scopus 로고
    • Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
    • Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature (2009) 461:282-6. doi:10.1038/nature08296.
    • (2009) Nature , vol.461 , pp. 282-286
    • Elliott, M.R.1    Chekeni, F.B.2    Trampont, P.C.3    Lazarowski, E.R.4    Kadl, A.5    Walk, S.F.6
  • 51
    • 33845708770 scopus 로고    scopus 로고
    • ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
    • Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, et al. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science (2006) 314:1792-5. doi:10.1126/science.1132559.
    • (2006) Science , vol.314 , pp. 1792-1795
    • Chen, Y.1    Corriden, R.2    Inoue, Y.3    Yip, L.4    Hashiguchi, N.5    Zinkernagel, A.6
  • 52
    • 79955040263 scopus 로고    scopus 로고
    • The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
    • Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol (2011) 186:4375-87. doi:10.4049/jimmunol.1003020.
    • (2011) J Immunol , vol.186 , pp. 4375-4387
    • Kouzaki, H.1    Iijima, K.2    Kobayashi, T.3    O'Grady, S.M.4    Kita, H.5
  • 53
    • 34547655975 scopus 로고    scopus 로고
    • Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
    • Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MAM, Muskens F, et al. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med (2007) 13:913-9. doi:10.1038/nm1617.
    • (2007) Nat Med , vol.13 , pp. 913-919
    • Idzko, M.1    Hammad, H.2    van Nimwegen, M.3    Kool, M.4    Willart, M.A.M.5    Muskens, F.6
  • 54
    • 0029665112 scopus 로고    scopus 로고
    • The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
    • Surprenant A, Rassendren F, Kawashima E, North RA, Buell G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science (1996) 272:735-8. doi:10.1126/science.272.5262.735.
    • (1996) Science , vol.272 , pp. 735-738
    • Surprenant, A.1    Rassendren, F.2    Kawashima, E.3    North, R.A.4    Buell, G.5
  • 55
    • 34247641287 scopus 로고    scopus 로고
    • P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability
    • Placido R, Auricchio G, Falzoni S, Battistini L, Colizzi V, Brunetti E, et al. P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability. Cell Immunol (2006) 244:10-8. doi:10.1016/j.cellimm.2007.02.001.
    • (2006) Cell Immunol , vol.244 , pp. 10-18
    • Placido, R.1    Auricchio, G.2    Falzoni, S.3    Battistini, L.4    Colizzi, V.5    Brunetti, E.6
  • 56
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 15:1170-8. doi:10.1038/nm.2028.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3    Aymeric, L.4    Ma, Y.5    Ortiz, C.6
  • 57
    • 78649414124 scopus 로고    scopus 로고
    • Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity
    • Weber FC, Esser PR, Müller T, Ganesan J, Pellegatti P, Simon MM, et al. Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity. J Exp Med (2010) 207:2609-19. doi:10.1084/jem.20092489.
    • (2010) J Exp Med , vol.207 , pp. 2609-2619
    • Weber, F.C.1    Esser, P.R.2    Müller, T.3    Ganesan, J.4    Pellegatti, P.5    Simon, M.M.6
  • 58
    • 79953758259 scopus 로고    scopus 로고
    • A potential role for P2X7R in allergic airway inflammation in mice and humans
    • Müller T, Vieira RP, Grimm M, Dürk T, Cicko S, Zeiser R, et al. A potential role for P2X7R in allergic airway inflammation in mice and humans. Am J Respir Cell Mol Biol (2011) 44:456-64. doi:10.1165/rcmb.2010-0129OC.
    • (2011) Am J Respir Cell Mol Biol , vol.44 , pp. 456-464
    • Müller, T.1    Vieira, R.P.2    Grimm, M.3    Dürk, T.4    Cicko, S.5    Zeiser, R.6
  • 59
    • 78649993400 scopus 로고    scopus 로고
    • Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
    • Wilhelm K, Ganesan J, Müller T, Dürr C, Grimm M, Beilhack A, et al. Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R. Nat Med (2010) 16:1434-8. doi:10.1038/nm.2242.
    • (2010) Nat Med , vol.16 , pp. 1434-1438
    • Wilhelm, K.1    Ganesan, J.2    Müller, T.3    Dürr, C.4    Grimm, M.5    Beilhack, A.6
  • 60
    • 84866990701 scopus 로고    scopus 로고
    • Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors
    • Kurashima Y, Amiya T, Nochi T, Fujisawa K, Haraguchi T, Iba H, et al. Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors. Nat Commun (2012) 3:1034. doi:10.1038/ncomms2023.
    • (2012) Nat Commun , vol.3 , pp. 1034
    • Kurashima, Y.1    Amiya, T.2    Nochi, T.3    Fujisawa, K.4    Haraguchi, T.5    Iba, H.6
  • 61
    • 77957101431 scopus 로고    scopus 로고
    • Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis
    • Riteau N, Gasse P, Fauconnier L, Gombault A, Couegnat M, Fick L, et al. Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. Am J Respir Crit Care Med (2010) 182:774-83. doi:10.1164/rccm.201003-0359OC.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 774-783
    • Riteau, N.1    Gasse, P.2    Fauconnier, L.3    Gombault, A.4    Couegnat, M.5    Fick, L.6
  • 62
    • 84925454929 scopus 로고    scopus 로고
    • P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation
    • Peng K, Liu L, Wei D, Lv Y, Wang G, Xiong W, et al. P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. Int J Mol Med (2015) 35:1179-88. doi:10.3892/ijmm.2015.2129.
    • (2015) Int J Mol Med , vol.35 , pp. 1179-1188
    • Peng, K.1    Liu, L.2    Wei, D.3    Lv, Y.4    Wang, G.5    Xiong, W.6
  • 63
    • 84906094303 scopus 로고    scopus 로고
    • Expression of high mobility group box 1 in inflamed dental pulp and its chemotactic effect on dental pulp cells
    • Zhang X, Jiang H, Gong Q, Fan C, Huang Y, Ling J. Expression of high mobility group box 1 in inflamed dental pulp and its chemotactic effect on dental pulp cells. Biochem Biophys Res Commun (2014) 450:1547-52. doi:10.1016/j.bbrc.2014.07.027.
    • (2014) Biochem Biophys Res Commun , vol.450 , pp. 1547-1552
    • Zhang, X.1    Jiang, H.2    Gong, Q.3    Fan, C.4    Huang, Y.5    Ling, J.6
  • 64
    • 51849084869 scopus 로고    scopus 로고
    • High mobility group box 1 protein inhibits the proliferation of human mesenchymal stem cells and promotes their migration and differentiation along osteoblastic pathway
    • Meng E, Guo Z, Wang H, Jin J, Wang J, Wang H, et al. High mobility group box 1 protein inhibits the proliferation of human mesenchymal stem cells and promotes their migration and differentiation along osteoblastic pathway. Stem Cells Dev (2008) 17:805-13. doi:10.1089/scd.2008.0276.
    • (2008) Stem Cells Dev , vol.17 , pp. 805-813
    • Meng, E.1    Guo, Z.2    Wang, H.3    Jin, J.4    Wang, J.5    Wang, H.6
  • 65
    • 79959730303 scopus 로고    scopus 로고
    • Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material
    • LotfiR, Eisenbacher J, Solgi G, Fuchs K, Yildiz T, Nienhaus C, et al. Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material. Eur J Immunol (2011) 41:2021-8. doi:10.1002/eji.201041324.
    • (2011) Eur J Immunol , vol.41 , pp. 2021-2028
    • Lotfi, R.1    Eisenbacher, J.2    Solgi, G.3    Fuchs, K.4    Yildiz, T.5    Nienhaus, C.6
  • 66
    • 84903205740 scopus 로고    scopus 로고
    • Regulation of high mobility group box 1 and hypoxia in the migration of mesenchymal stem cells
    • Xie H-L, Zhang Y, Huang Y-Z, Li S, Wu C-G, Jiao X-F, et al. Regulation of high mobility group box 1 and hypoxia in the migration of mesenchymal stem cells. Cell Biol Int (2014) 38:892-7. doi:10.1002/cbin.10279.
    • (2014) Cell Biol Int , vol.38 , pp. 892-897
    • Xie, H.-L.1    Zhang, Y.2    Huang, Y.-Z.3    Li, S.4    Wu, C.-G.5    Jiao, X.-F.6
  • 67
    • 79955619770 scopus 로고    scopus 로고
    • PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia
    • Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, et al. PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia. Proc Natl Acad Sci U S A (2011) 108:6609-14. doi:10.1073/pnas.1016753108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 6609-6614
    • Tamai, K.1    Yamazaki, T.2    Chino, T.3    Ishii, M.4    Otsuru, S.5    Kikuchi, Y.6
  • 68
    • 84930572934 scopus 로고    scopus 로고
    • Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death
    • Vogel S, Börger V, Peters C, Förster M, Liebfried P, Metzger K, et al. Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death. Cell Death Differ (2015) 22:1219-30. doi:10.1038/cdd.2014.225.
    • (2015) Cell Death Differ , vol.22 , pp. 1219-1230
    • Vogel, S.1    Börger, V.2    Peters, C.3    Förster, M.4    Liebfried, P.5    Metzger, K.6
  • 69
    • 84899867933 scopus 로고    scopus 로고
    • High-mobility group box-1 and its role in angiogenesis
    • Yang S, Xu L, Yang T, Wang F. High-mobility group box-1 and its role in angiogenesis. J Leukoc Biol (2014) 95:563-74. doi:10.1189/jlb.0713412.
    • (2014) J Leukoc Biol , vol.95 , pp. 563-574
    • Yang, S.1    Xu, L.2    Yang, T.3    Wang, F.4
  • 70
    • 33846844786 scopus 로고    scopus 로고
    • High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells
    • Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, et al. High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res (2007) 100:204-12. doi:10.1161/01.RES.0000257774.55970.f4.
    • (2007) Circ Res , vol.100 , pp. 204-212
    • Chavakis, E.1    Hain, A.2    Vinci, M.3    Carmona, G.4    Bianchi, M.E.5    Vajkoczy, P.6
  • 71
    • 29644441337 scopus 로고    scopus 로고
    • Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine
    • Mitola S, Belleri M, Urbinati C, Coltrini D, Sparatore B, Pedrazzi M, et al. Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine. J Immunol (2006) 176:12-5. doi:10.4049/jimmunol.176.1.12.
    • (2006) J Immunol , vol.176 , pp. 12-15
    • Mitola, S.1    Belleri, M.2    Urbinati, C.3    Coltrini, D.4    Sparatore, B.5    Pedrazzi, M.6
  • 73
    • 84901249389 scopus 로고    scopus 로고
    • Leukocyte HMGB1 is required for vessel remodeling in regenerating muscles
    • Campana L, Santarella F, Esposito A, Maugeri N, Rigamonti E, Monno A, et al. Leukocyte HMGB1 is required for vessel remodeling in regenerating muscles. J Immunol (2014) 192:5257-64. doi:10.4049/jimmunol.1300938.
    • (2014) J Immunol , vol.192 , pp. 5257-5264
    • Campana, L.1    Santarella, F.2    Esposito, A.3    Maugeri, N.4    Rigamonti, E.5    Monno, A.6
  • 74
    • 84894374794 scopus 로고    scopus 로고
    • HMGB1 contributes to regeneration after spinal cord injury in adult zebrafish
    • Fang P, Pan H-C, Lin SL, Zhang W-Q, Rauvala H, Schachner M, et al. HMGB1 contributes to regeneration after spinal cord injury in adult zebrafish. Mol Neurobiol (2014) 49:472-83. doi:10.1007/s12035-013-8533-4.
    • (2014) Mol Neurobiol , vol.49 , pp. 472-483
    • Fang, P.1    Pan, H.-C.2    Lin, S.L.3    Zhang, W.-Q.4    Rauvala, H.5    Schachner, M.6
  • 75
    • 84880068491 scopus 로고    scopus 로고
    • HMGB1 protein does not mediate the inflammatory response in spontaneous spinal cord regeneration: a hint for CNS regeneration
    • Dong Y, Gu Y, Huan Y, Wang Y, Liu Y, Liu M, et al. HMGB1 protein does not mediate the inflammatory response in spontaneous spinal cord regeneration: a hint for CNS regeneration. J Biol Chem (2013) 288:18204-18. doi:10.1074/jbc. M113.463810.
    • (2013) J Biol Chem , vol.288 , pp. 18204-18218
    • Dong, Y.1    Gu, Y.2    Huan, Y.3    Wang, Y.4    Liu, Y.5    Liu, M.6
  • 76
    • 43749112963 scopus 로고    scopus 로고
    • High-mobility group box 1 protein in human and murine skin: involvement in wound healing
    • Straino S, Di Carlo A, Mangoni A, De Mori R, Guerra L, Maurelli R, et al. High-mobility group box 1 protein in human and murine skin: involvement in wound healing. J Invest Dermatol (2008) 128:1545-53. doi:10.1038/sj.jid.5701212.
    • (2008) J Invest Dermatol , vol.128 , pp. 1545-1553
    • Straino, S.1    Di Carlo, A.2    Mangoni, A.3    De Mori, R.4    Guerra, L.5    Maurelli, R.6
  • 77
    • 84874897144 scopus 로고    scopus 로고
    • The alarmin HMGB-1 influences healing outcomes in fetal skin wounds
    • Dardenne AD, WulffBC, Wilgus TA. The alarmin HMGB-1 influences healing outcomes in fetal skin wounds. Wound Repair Regen (2013) 21:282-91. doi:10.1111/wrr.12028.
    • (2013) Wound Repair Regen , vol.21 , pp. 282-291
    • Dardenne, A.D.1    Wulff, B.C.2    Wilgus, T.A.3
  • 78
    • 51749118759 scopus 로고    scopus 로고
    • High-mobility group box 1 restores cardiac function after myocardial infarction in transgenic mice
    • Kitahara T, Takeishi Y, Harada M, Niizeki T, Suzuki S, Sasaki T, et al. High-mobility group box 1 restores cardiac function after myocardial infarction in transgenic mice. Cardiovasc Res (2008) 80:40-6. doi:10.1093/cvr/cvn163.
    • (2008) Cardiovasc Res , vol.80 , pp. 40-46
    • Kitahara, T.1    Takeishi, Y.2    Harada, M.3    Niizeki, T.4    Suzuki, S.5    Sasaki, T.6
  • 79
    • 32944480771 scopus 로고    scopus 로고
    • Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation
    • Limana F, Germani A, Zacheo A, Kajstura J, Di Carlo A, Borsellino G, et al. Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation. Circ Res (2005) 97:e73-83. doi:10.1161/01.RES.0000186276.06104.04.
    • (2005) Circ Res , vol.97 , pp. e73-e83
    • Limana, F.1    Germani, A.2    Zacheo, A.3    Kajstura, J.4    Di Carlo, A.5    Borsellino, G.6
  • 80
    • 42749083870 scopus 로고    scopus 로고
    • HMGB1-stimulated human primary cardiac fibroblasts exert a paracrine action on human and murine cardiac stem cells
    • Rossini A, Zacheo A, Mocini D, Totta P, Facchiano A, Castoldi R, et al. HMGB1-stimulated human primary cardiac fibroblasts exert a paracrine action on human and murine cardiac stem cells. J Mol Cell Cardiol (2008) 44:683-93. doi:10.1016/j.yjmcc.2008.01.009.
    • (2008) J Mol Cell Cardiol , vol.44 , pp. 683-693
    • Rossini, A.1    Zacheo, A.2    Mocini, D.3    Totta, P.4    Facchiano, A.5    Castoldi, R.6
  • 81
    • 54449095004 scopus 로고    scopus 로고
    • Modulated inflammation by injection of high-mobility group box 1 recovers post-infarction chronically failing heart
    • Takahashi K, Fukushima S, Yamahara K, Yashiro K, Shintani Y, Coppen SR, et al. Modulated inflammation by injection of high-mobility group box 1 recovers post-infarction chronically failing heart. Circulation (2008) 118:S106-14. doi:10.1161/CIRCULATIONAHA.107.757443.
    • (2008) Circulation , vol.118 , pp. S106-S114
    • Takahashi, K.1    Fukushima, S.2    Yamahara, K.3    Yashiro, K.4    Shintani, Y.5    Coppen, S.R.6
  • 82
    • 84885020671 scopus 로고    scopus 로고
    • Transcriptional profiling of HMGB1-induced myocardial repair identifies a key role for Notch signaling
    • Limana F, Esposito G, Fasanaro P, Foglio E, Arcelli D, Voellenkle C, et al. Transcriptional profiling of HMGB1-induced myocardial repair identifies a key role for Notch signaling. Mol Ther (2013) 21:1841-51. doi:10.1038/mt.2013.137.
    • (2013) Mol Ther , vol.21 , pp. 1841-1851
    • Limana, F.1    Esposito, G.2    Fasanaro, P.3    Foglio, E.4    Arcelli, D.5    Voellenkle, C.6
  • 84
    • 59449099249 scopus 로고    scopus 로고
    • Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling
    • Kohno T, Anzai T, Naito K, Miyasho T, Okamoto M, Yokota H, et al. Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling. Cardiovasc Res (2009) 81:565-73. doi:10.1093/cvr/cvn291.
    • (2009) Cardiovasc Res , vol.81 , pp. 565-573
    • Kohno, T.1    Anzai, T.2    Naito, K.3    Miyasho, T.4    Okamoto, M.5    Yokota, H.6
  • 87
    • 0035911959 scopus 로고    scopus 로고
    • The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells
    • Degryse B, Bonaldi T, Scaffidi P, Müller S, Resnati M, Sanvito F, et al. The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol (2001) 152:1197-206. doi:10.1083/jcb.152.6.1197.
    • (2001) J Cell Biol , vol.152 , pp. 1197-1206
    • Degryse, B.1    Bonaldi, T.2    Scaffidi, P.3    Müller, S.4    Resnati, M.5    Sanvito, F.6
  • 88
    • 2442645301 scopus 로고    scopus 로고
    • Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding
    • Sorci G, Riuzzi F, Arcuri C, Giambanco I, Donato R. Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding. Mol Cell Biol (2004) 24:4880-94. doi:10.1128/MCB.24.11.4880-4894.2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 4880-4894
    • Sorci, G.1    Riuzzi, F.2    Arcuri, C.3    Giambanco, I.4    Donato, R.5
  • 89
    • 0842266582 scopus 로고    scopus 로고
    • Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation
    • Palumbo R, Sampaolesi M, De Marchis F, Tonlorenzi R, Colombetti S, Mondino A, et al. Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation. J Cell Biol (2004) 164:441-9. doi:10.1083/jcb.200304135.
    • (2004) J Cell Biol , vol.164 , pp. 441-449
    • Palumbo, R.1    Sampaolesi, M.2    De Marchis, F.3    Tonlorenzi, R.4    Colombetti, S.5    Mondino, A.6
  • 90
    • 84864117083 scopus 로고    scopus 로고
    • Immunoregulation through extracellular nucleotides
    • Vitiello L, Gorini S, Rosano G, la Sala A. Immunoregulation through extracellular nucleotides. Blood (2012) 120:511-8. doi:10.1182/blood-2012-01-406496.
    • (2012) Blood , vol.120 , pp. 511-518
    • Vitiello, L.1    Gorini, S.2    Rosano, G.3    la Sala, A.4
  • 91
    • 40949119063 scopus 로고    scopus 로고
    • Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells
    • Yu N, Erb L, Shivaji R, Weisman GA, Seye CI. Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells. Circ Res (2008) 102:581-8. doi:10.1161/CIRCRESAHA.107.162271.
    • (2008) Circ Res , vol.102 , pp. 581-588
    • Yu, N.1    Erb, L.2    Shivaji, R.3    Weisman, G.A.4    Seye, C.I.5
  • 92
    • 0030778360 scopus 로고    scopus 로고
    • Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase
    • Albert JL, Boyle JP, Roberts JA, Challiss RA, Gubby SE, Boarder MR. Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase. Br J Pharmacol (1997) 122:935-41. doi:10.1038/sj.bjp.0701453.
    • (1997) Br J Pharmacol , vol.122 , pp. 935-941
    • Albert, J.L.1    Boyle, J.P.2    Roberts, J.A.3    Challiss, R.A.4    Gubby, S.E.5    Boarder, M.R.6
  • 93
    • 0032941657 scopus 로고    scopus 로고
    • Chemotactic, mitogenic, and angiogenic actions of UTP on vascular endothelial cells
    • Satterwhite CM, Farrelly AM, Bradley ME. Chemotactic, mitogenic, and angiogenic actions of UTP on vascular endothelial cells. Am J Physiol (1999) 276:H1091-7.
    • (1999) Am J Physiol , vol.276 , pp. H1091-H1097
    • Satterwhite, C.M.1    Farrelly, A.M.2    Bradley, M.E.3
  • 94
    • 84904395957 scopus 로고    scopus 로고
    • P2Y2 R activation by nucleotides promotes skin wound-healing process
    • Jin H, Seo J, Eun SY, Joo YN, Park SW, Lee JH, et al. P2Y2 R activation by nucleotides promotes skin wound-healing process. Exp Dermatol (2014) 23:480-5. doi:10.1111/exd.12440.
    • (2014) Exp Dermatol , vol.23 , pp. 480-485
    • Jin, H.1    Seo, J.2    Eun, S.Y.3    Joo, Y.N.4    Park, S.W.5    Lee, J.H.6
  • 95
    • 0031812161 scopus 로고    scopus 로고
    • Extracellular ATP: a growth factor for vascular smooth muscle cells
    • Erlinge D. Extracellular ATP: a growth factor for vascular smooth muscle cells. Gen Pharmacol (1998) 31:1-8. doi:10.1016/S0306-3623(97)00420-5.
    • (1998) Gen Pharmacol , vol.31 , pp. 1-8
    • Erlinge, D.1
  • 96
    • 84918782209 scopus 로고    scopus 로고
    • Extracellular nucleotides from dying cells act as molecular signals to promote wound repair in renal tubular injury
    • Nakagawa S, Omura T, Yonezawa A, Yano I, Nakagawa T, Matsubara K. Extracellular nucleotides from dying cells act as molecular signals to promote wound repair in renal tubular injury. Am J Physiol Renal Physiol (2014) 307:F1404-11. doi:10.1152/ajprenal.00196.2014.
    • (2014) Am J Physiol Renal Physiol , vol.307 , pp. F1404-F1411
    • Nakagawa, S.1    Omura, T.2    Yonezawa, A.3    Yano, I.4    Nakagawa, T.5    Matsubara, K.6
  • 97
    • 71149121137 scopus 로고    scopus 로고
    • ATP release after partial hepatectomy regulates liver regeneration in the rat
    • Gonzales E, Julien B, Serrière-Lanneau V, Nicou A, Doignon I, Lagoudakis L, et al. ATP release after partial hepatectomy regulates liver regeneration in the rat. J Hepatol (2010) 52:54-62. doi:10.1016/j.jhep.2009.10.005.
    • (2010) J Hepatol , vol.52 , pp. 54-62
    • Gonzales, E.1    Julien, B.2    Serrière-Lanneau, V.3    Nicou, A.4    Doignon, I.5    Lagoudakis, L.6
  • 98
    • 84918534316 scopus 로고    scopus 로고
    • Calcium-dependent neuroepithelial contractions expel damaged cells from the developing brain
    • Herrgen L, Voss OP, Akerman CJ. Calcium-dependent neuroepithelial contractions expel damaged cells from the developing brain. Dev Cell (2014) 31:599-613. doi:10.1016/j.devcel.2014.10.012.
    • (2014) Dev Cell , vol.31 , pp. 599-613
    • Herrgen, L.1    Voss, O.P.2    Akerman, C.J.3
  • 99
    • 84907459149 scopus 로고    scopus 로고
    • Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation
    • Weihs AM, Fuchs C, Teuschl AH, Hartinger J, Slezak P, Mittermayr R, et al. Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation. J Biol Chem (2014) 289:27090-104. doi:10.1074/jbc. M114.580936.
    • (2014) J Biol Chem , vol.289 , pp. 27090-27104
    • Weihs, A.M.1    Fuchs, C.2    Teuschl, A.H.3    Hartinger, J.4    Slezak, P.5    Mittermayr, R.6
  • 100
    • 36849012449 scopus 로고    scopus 로고
    • G alpha(q/11)-coupled P2Y2 nucleotide receptor inhibits human keratinocyte spreading and migration
    • Taboubi S, Milanini J, Delamarre E, Parat F, Garrouste F, Pommier G, et al. G alpha(q/11)-coupled P2Y2 nucleotide receptor inhibits human keratinocyte spreading and migration. FASEB J (2007) 21:4047-58. doi:10.1096/fj.06-7476com.
    • (2007) FASEB J , vol.21 , pp. 4047-4058
    • Taboubi, S.1    Milanini, J.2    Delamarre, E.3    Parat, F.4    Garrouste, F.5    Pommier, G.6
  • 101
    • 20144389797 scopus 로고    scopus 로고
    • Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways
    • Kaczmarek E, Erb L, Koziak K, Jarzyna R, Wink MR, Guckelberger O, et al. Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways. Thromb Haemost (2005) 93:735-42. doi:10.1267/THRO05040735.
    • (2005) Thromb Haemost , vol.93 , pp. 735-742
    • Kaczmarek, E.1    Erb, L.2    Koziak, K.3    Jarzyna, R.4    Wink, M.R.5    Guckelberger, O.6
  • 102
    • 84898612123 scopus 로고    scopus 로고
    • Rapid granulation tissue regeneration by intracellular ATP delivery-a comparison with Regranex
    • Howard JD, Sarojini H, Wan R, Chien S. Rapid granulation tissue regeneration by intracellular ATP delivery-a comparison with Regranex. PLoS One (2014) 9:e91787. doi:10.1371/journal.pone.0091787.
    • (2014) PLoS One , vol.9
    • Howard, J.D.1    Sarojini, H.2    Wan, R.3    Chien, S.4
  • 103
    • 84908360531 scopus 로고    scopus 로고
    • Mechanosensitive ATP release from hemichannels and Ca2+ influx through TRPC6 accelerate wound closure in keratinocytes
    • Takada H, Furuya K, Sokabe M. Mechanosensitive ATP release from hemichannels and Ca2+ influx through TRPC6 accelerate wound closure in keratinocytes. J Cell Sci (2014) 127:4159-71. doi:10.1242/jcs.147314.
    • (2014) J Cell Sci , vol.127 , pp. 4159-4171
    • Takada, H.1    Furuya, K.2    Sokabe, M.3
  • 104
    • 84930439563 scopus 로고    scopus 로고
    • Osmotic surveillance mediates rapid wound closure through nucleotide release
    • Gault WJ, Enyedi B, Niethammer P. Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol (2014) 207:767-82. doi:10.1083/jcb.201408049.
    • (2014) J Cell Biol , vol.207 , pp. 767-782
    • Gault, W.J.1    Enyedi, B.2    Niethammer, P.3
  • 105
    • 84905463826 scopus 로고    scopus 로고
    • Activation of P2RY11 and ATP release by lipoxin A4 restores the airway surface liquid layer and epithelial repair in cystic fibrosis
    • Higgins G, Buchanan P, Perriere M, Al-Alawi M, Costello RW, Verriere V, et al. Activation of P2RY11 and ATP release by lipoxin A4 restores the airway surface liquid layer and epithelial repair in cystic fibrosis. Am J Respir Cell Mol Biol (2014) 51:178-90. doi:10.1165/rcmb.2012-0424OC.
    • (2014) Am J Respir Cell Mol Biol , vol.51 , pp. 178-190
    • Higgins, G.1    Buchanan, P.2    Perriere, M.3    Al-Alawi, M.4    Costello, R.W.5    Verriere, V.6
  • 106
    • 78049404838 scopus 로고    scopus 로고
    • Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes
    • Hill LM, Gavala ML, Lenertz LY, Bertics PJ. Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes. J Immunol (2010) 185:3028-34. doi:10.4049/jimmunol.1001298.
    • (2010) J Immunol , vol.185 , pp. 3028-3034
    • Hill, L.M.1    Gavala, M.L.2    Lenertz, L.Y.3    Bertics, P.J.4
  • 107
    • 53449100271 scopus 로고    scopus 로고
    • Regulation by P2X7: epithelial migration and stromal organization in the cornea
    • Mayo C, Ren R, Rich C, Stepp MA, Trinkaus-Randall V. Regulation by P2X7: epithelial migration and stromal organization in the cornea. Invest Ophthalmol Vis Sci (2008) 49:4384-91. doi:10.1167/iovs.08-1688.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4384-4391
    • Mayo, C.1    Ren, R.2    Rich, C.3    Stepp, M.A.4    Trinkaus-Randall, V.5
  • 108
    • 84902181474 scopus 로고    scopus 로고
    • Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair
    • MacLeod AS, Rudolph R, Corriden R, Ye I, Garijo O, Havran WL. Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. J Immunol (2014) 192:5695-702. doi:10.4049/jimmunol.1303297.
    • (2014) J Immunol , vol.192 , pp. 5695-5702
    • MacLeod, A.S.1    Rudolph, R.2    Corriden, R.3    Ye, I.4    Garijo, O.5    Havran, W.L.6
  • 109
    • 0003721825 scopus 로고
    • Une histoire de l'hérédité. Paris: Editions Gallimard-coll. Tel
    • Jacob F. La Logique du vivant. Une histoire de l'hérédité. Paris: Editions Gallimard-coll. Tel (1970).
    • (1970) La Logique du vivant
    • Jacob, F.1
  • 110
    • 78649526394 scopus 로고    scopus 로고
    • Sterile inflammation: sensing and reacting to damage
    • Chen GY, Nuñez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol (2010) 10:826-37. doi:10.1038/nri2873.
    • (2010) Nat Rev Immunol , vol.10 , pp. 826-837
    • Chen, G.Y.1    Nuñez, G.2
  • 111
    • 70149123249 scopus 로고    scopus 로고
    • DAMPs and inflammatory processes: the role of redox in the different outcomes
    • Carta S, Castellani P, Delfino L, Tassi S, Venè R, Rubartelli A. DAMPs and inflammatory processes: the role of redox in the different outcomes. J Leukoc Biol (2009) 86:549-55. doi:10.1189/jlb.1008598.
    • (2009) J Leukoc Biol , vol.86 , pp. 549-555
    • Carta, S.1    Castellani, P.2    Delfino, L.3    Tassi, S.4    Venè, R.5    Rubartelli, A.6
  • 112
    • 84904173553 scopus 로고    scopus 로고
    • Metabolism of stromal and immune cells in health and disease
    • Ghesquière B, Wong BW, Kuchnio A, Carmeliet P. Metabolism of stromal and immune cells in health and disease. Nature (2014) 511:167-76. doi:10.1038/nature13312.
    • (2014) Nature , vol.511 , pp. 167-176
    • Ghesquière, B.1    Wong, B.W.2    Kuchnio, A.3    Carmeliet, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.