p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress

Cell Stem Cell

Volumn 19, Issue 2, 2016, Pages 192-204

  Karigane, Daiki ^a,b   Kobayashi, Hiroshi ^a   Morikawa, Takayuki ^a   Ootomo, Yukako ^a,c   Sakai, Mashito ^a   Nagamatsu, Go ^d   Kubota, Yoshiaki ^b   Goda, Nobuhito ^c   Matsumoto, Michihiro ^a   Nishimura, Emi K ^e   Soga, Tomoyoshi ^f   Otsu, Kinya ^g   Suematsu, Makoto ^b   Okamoto, Shinichiro ^b   Suda, Toshio ^h   Takubo, Keiyo ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c WASEDA UNIVERSITY   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^f KEIO UNIVERSITY   (Japan)

^g KING'S COLLEGE LONDON   (United Kingdom)

^h NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

INOSINATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 14; PURINE; REACTIVE OXYGEN METABOLITE; IMPDH2, MOUSE; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITF PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE P38; PURINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL HOMING; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GLYCOLYSIS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; METABOLIC ACTIVATION; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURINE METABOLISM; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CYCLE; CYTOLOGY; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METABOLISM; MUTATION; PHENOTYPE; PHYSIOLOGICAL STRESS;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; ENZYME ACTIVATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; IMP DEHYDROGENASE; MICE, INBRED C57BL; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MUTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PURINES; REACTIVE OXYGEN SPECIES; STRESS, PHYSIOLOGICAL;

EID: 84990902034     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.05.013     Document Type: Article

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