Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma

Molecular Cell

Volumn 62, Issue 1, 2016, Pages 34-46

  Tan, Justin L ^a,b   Fogley, Rachel D ^a,b   Flynn, Ryan A ^c   Ablain, Julien ^a,b   Yang, Song ^a,b   Saint André, Violaine ^d   Fan, Zi Peng ^d   Do, Brian T ^c   Laga, Alvaro C ^e   Fujinaga, Koh ^f   Santoriello, Cristina ^a,b   Greer, Celeste B ^g   Kim, Yoon Jung ^h   Clohessy, John G ⁱ   Bothmer, Anne ⁱ   Pandell, Nicole ⁱ   Avagyan, Serine ^a,b   Brogie, John E ^j   van Rooijen, Ellen ^a,b   Hagedorn, Elliott J ^a,b   Shyh Chang, Ng ^k   White, Richard M ^l   Price, David H ^j   Pandolfi, Pier Paolo ⁱ   Peterlin, B Matija ^f   Zhou, Yi ^a,b   Kim, Tae Hoon ^h   Asara, John M ⁱ   Chang, Howard Y ^c   Young, Richard A ^d   Zon, Leonard I ^a,b   more..

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF TEXAS AT DALLAS   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j UNIVERSITY OF IOWA   (United States)

^k GENOME INSTITUTE OF SINGAPORE   (Singapore)

^l MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HEXIM1 PROTEIN; MEMBRANE ANTIGEN; MESSENGER RNA; NUCLEOTIDE; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; HEXIM1 PROTEIN, HUMAN; ONCOPROTEIN; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PYRIMIDINE DERIVATIVE; RNA BINDING PROTEIN; ZEBRAFISH PROTEIN;

A375 CELL LINE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL SPECIFICITY; CELL VIABILITY; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MELANOMA; MOUSE; NONHUMAN; NUCLEOTIDE DEPLETION; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA STABILITY; TRANSCRIPTION ELONGATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; ZEBRA FISH; ANIMAL; EXPERIMENTAL MELANOMA; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELANOMA; MELANOMA, EXPERIMENTAL; ONCOGENE PROTEINS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PYRIMIDINES; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84962467364     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.03.013     Document Type: Article

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