메뉴 건너뛰기




Volumn 2017, Issue , 2017, Pages

Genetic and Epigenetic Regulation of Aortic Aneurysms

Author keywords

[No Author keywords available]

Indexed keywords

UNTRANSLATED RNA; LIPID; TRANSFORMING GROWTH FACTOR BETA;

EID: 85010370184     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2017/7268521     Document Type: Review
Times cited : (59)

References (168)
  • 1
    • 70149115051 scopus 로고    scopus 로고
    • Understanding abdominal aortic aneurysm
    • N. L. Weintraub, "Understanding abdominal aortic aneurysm," The New England Journal of Medicine, vol. 361, no. 11, pp. 1114-1116, 2009.
    • (2009) The New England Journal of Medicine , vol.361 , Issue.11 , pp. 1114-1116
    • Weintraub, N.L.1
  • 4
    • 33748752789 scopus 로고    scopus 로고
    • Familial thoracic aortic aneurysms and dissections-incidence, modes of inheritance, and phenotypic patterns
    • G. Albornoz, M. A. Coady, M. Roberts et al., "Familial thoracic aortic aneurysms and dissections-incidence, modes of inheritance, and phenotypic patterns," Annals of Toracic Surgery, vol. 82, no. 4, pp. 1400-1405, 2006.
    • (2006) Annals of Toracic Surgery , vol.82 , Issue.4 , pp. 1400-1405
    • Albornoz, G.1    Coady, M.A.2    Roberts, M.3
  • 5
    • 0025886783 scopus 로고
    • Marfan syndrome caused by a recurrent de novo missense mutation in the fbrillin gene
    • H. C. Dietz, C. R. Cutting, R. E. Pyeritz et al., "Marfan syndrome caused by a recurrent de novo missense mutation in the fbrillin gene," Nature, vol. 352, no. 6333, pp. 337-339, 1991.
    • (1991) Nature , vol.352 , Issue.6333 , pp. 337-339
    • Dietz, H.C.1    Cutting, C.R.2    Pyeritz, R.E.3
  • 6
    • 59449108914 scopus 로고    scopus 로고
    • Clinical and molecular study of 320 children with marfan syndrome and related type i fbrillinopathies in a series of 1009 probands with pathogenic FBN1 mutations
    • L. Faivre, A. Masurel-Paulet, G. Collod-Beroud et al., "Clinical and molecular study of 320 children with marfan syndrome and related type I fbrillinopathies in a series of 1009 probands with pathogenic FBN1 mutations," Pediatrics, vol. 123, no. 1, pp. 391-398, 2009.
    • (2009) Pediatrics , vol.123 , Issue.1 , pp. 391-398
    • Faivre, L.1    Masurel-Paulet, A.2    Collod-Beroud, G.3
  • 7
    • 80053385386 scopus 로고    scopus 로고
    • Genome-wide association study identifes a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1
    • S. A. LeMaire, M.-L. N. McDonald, D.-C. Guo et al., "Genome-wide association study identifes a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1," Nature Genetics, vol. 43, no. 10, pp. 996-1000, 2011.
    • (2011) Nature Genetics , vol.43 , Issue.10 , pp. 996-1000
    • Lemaire, S.A.1    McDonald, M.-L.N.2    Guo, D.-C.3
  • 8
    • 17144446828 scopus 로고    scopus 로고
    • Update of the UMD-FBN1 mutation database and creation of an FBN1 polymorphism database
    • G. Collod-Béroud, S. Le Bourdelles, L. Ades et al., "Update of the UMD-FBN1 mutation database and creation of an FBN1 polymorphism database," Human Mutation, vol. 22, no. 3, pp. 199-208, 2003.
    • (2003) Human Mutation , vol.22 , Issue.3 , pp. 199-208
    • Collod-Béroud, G.1    Le Bourdelles, S.2    Ades, L.3
  • 9
    • 20144367207 scopus 로고    scopus 로고
    • A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2
    • B. L. Loeys, J. Chen, E. R. Neptune et al., "A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2," Nature Genetics, vol. 37, no. 3, pp. 275-281, 2005.
    • (2005) Nature Genetics , vol.37 , Issue.3 , pp. 275-281
    • Loeys, B.L.1    Chen, J.2    Neptune, E.R.3
  • 10
    • 74449083978 scopus 로고    scopus 로고
    • Association of the TGF-α receptor genes with abdominal aortic aneurysm
    • A. F. Baas, J. Medic, R. van 't Slot et al., "Association of the TGF-α receptor genes with abdominal aortic aneurysm," European Journal of Human Genetics, vol. 18, no. 2, pp. 240-244, 2010.
    • (2010) European Journal of Human Genetics , vol.18 , Issue.2 , pp. 240-244
    • Baas, A.F.1    Medic, J.2    Slot 'T R.Van3
  • 11
    • 0025370518 scopus 로고
    • Inheritance of an RNA splicing mutation (G+ 1 IVS20) in the type III procollagen gene (COL3A1) in a family having aortic aneurysms and easy bruisability: Phenotypic overlap between familial arterial aneurysms and Ehlers-Danlos syndrome type IV
    • S. Kontusaari, G. Tromp, H. Kuivaniemi, R. L. Ladda, and D. J. Prockop, "Inheritance of an RNA splicing mutation (G+ 1 IVS20) in the type III procollagen gene (COL3A1) in a family having aortic aneurysms and easy bruisability: phenotypic overlap between familial arterial aneurysms and Ehlers-Danlos syndrome type IV," American Journal of Human Genetics, vol. 47, no. 1, pp. 112-120, 1990.
    • (1990) American Journal of Human Genetics , vol.47 , Issue.1 , pp. 112-120
    • Kontusaari, S.1    Tromp, G.2    Kuivaniemi, H.3    Ladda, R.L.4    Prockop, D.J.5
  • 12
    • 79952836042 scopus 로고    scopus 로고
    • Haploinsufciency of the murine Col3a1 locus causes aortic dissection: A novel model of the vascular type of EhlersDanlos syndrome
    • L. B. Smith, P. W. F. Hadoke, E. Dyer et al., "Haploinsufciency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of EhlersDanlos syndrome," Cardiovascular Research, vol. 90, no. 1, pp. 182-190, 2011.
    • (2011) Cardiovascular Research , vol.90 , Issue.1 , pp. 182-190
    • Smith, L.B.1    Hadoke, P.W.F.2    Dyer, E.3
  • 13
    • 84880732002 scopus 로고    scopus 로고
    • Angiotensin II promotes thoracic aortic dissections and ruptures in Col3a1 haploinsufcient mice
    • J. Faugeroux, H. Nematalla, W. Li et al., "Angiotensin II promotes thoracic aortic dissections and ruptures in Col3a1 haploinsufcient mice," Hypertension, vol. 62, no. 1, pp. 203-208, 2013.
    • (2013) Hypertension , vol.62 , Issue.1 , pp. 203-208
    • Faugeroux, J.1    Nematalla, H.2    Li, W.3
  • 14
    • 20444471566 scopus 로고    scopus 로고
    • Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms
    • T. Ogata, H. Shibamura, G. Tromp et al., "Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms," Journal of Vascular Surgery, vol. 41, no. 6, pp. 1036-1042, 2005.
    • (2005) Journal of Vascular Surgery , vol.41 , Issue.6 , pp. 1036-1042
    • Ogata, T.1    Shibamura, H.2    Tromp, G.3
  • 15
    • 34848825045 scopus 로고    scopus 로고
    • MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II
    • H. Pannu, V. Tran-Fadulu, C. L. Papke et al., "MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II," Human Molecular Genetics, vol. 16, no. 20, pp. 2453-2462, 2007.
    • (2007) Human Molecular Genetics , vol.16 , Issue.20 , pp. 2453-2462
    • Pannu, H.1    Tran-Fadulu, V.2    Papke, C.L.3
  • 16
    • 33644627494 scopus 로고    scopus 로고
    • Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus
    • L. Zhu, R. Vranckx, P. K. Van Kien et al., "Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus," Nature Genetics, vol. 38, no. 3, pp. 343-349, 2006.
    • (2006) Nature Genetics , vol.38 , Issue.3 , pp. 343-349
    • Zhu, L.1    Vranckx, R.2    Van Kien, P.K.3
  • 17
    • 36549071997 scopus 로고    scopus 로고
    • Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections
    • D.-C. Guo, H. Pannu, V. Tran-Fadulu et al., "Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections," Nature Genetics, vol. 39, no. 12, pp. 1488-1493, 2007.
    • (2007) Nature Genetics , vol.39 , Issue.12 , pp. 1488-1493
    • Guo, D.-C.1    Pannu, H.2    Tran-Fadulu, V.3
  • 18
    • 65149088429 scopus 로고    scopus 로고
    • Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease
    • D.-C. Guo, C. L. Papke, V. Tran-Fadulu et al., "Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease," The American Journal of Human Genetics, vol. 84, no. 5, pp. 617-627, 2009.
    • (2009) The American Journal of Human Genetics , vol.84 , Issue.5 , pp. 617-627
    • Guo, D.-C.1    Papke, C.L.2    Tran-Fadulu, V.3
  • 19
    • 84954424738 scopus 로고    scopus 로고
    • LOX mutations predispose to thoracic aortic aneurysms and dissections
    • D.-C. Guo, E. S. Regalado, L. Gong et al., "LOX mutations predispose to thoracic aortic aneurysms and dissections," Circulation Research, vol. 118, no. 6, pp. 928-934, 2016.
    • (2016) Circulation Research , vol.118 , Issue.6 , pp. 928-934
    • Guo, D.-C.1    Regalado, E.S.2    Gong, L.3
  • 20
    • 84920737567 scopus 로고    scopus 로고
    • MAT2A mutations predispose individuals to thoracic aortic aneurysms
    • D.-C. Guo, L. Gong, E. S. Regalado et al., "MAT2A mutations predispose individuals to thoracic aortic aneurysms," American Journal of Human Genetics, vol. 96, no. 1, pp. 170-177, 2015.
    • (2015) American Journal of Human Genetics , vol.96 , Issue.1 , pp. 170-177
    • Guo, D.-C.1    Gong, L.2    Regalado, E.S.3
  • 21
    • 80052584397 scopus 로고    scopus 로고
    • Exome sequencing identifes SMAD3 mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms
    • E. S. Regalado, D.-C. Guo, C. Villamizar et al., "Exome sequencing identifes SMAD3 mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms," Circulation Research, vol. 109, no. 6, pp. 680-686, 2011.
    • (2011) Circulation Research , vol.109 , Issue.6 , pp. 680-686
    • Regalado, E.S.1    Guo, D.-C.2    Villamizar, C.3
  • 22
    • 79251602475 scopus 로고    scopus 로고
    • Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis
    • I. M. B. H. Van De Laar, R. A. Oldenburg, G. Pals et al., "Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis," Nature Genetics, vol. 43, no. 2, pp. 121-126, 2011.
    • (2011) Nature Genetics , vol.43 , Issue.2 , pp. 121-126
    • Laar De Van, H.B.I.M.1    Oldenburg, R.A.2    Pals, G.3
  • 23
    • 19944406428 scopus 로고    scopus 로고
    • Lowering of Pkd1 expression is sufcient to cause polycystic kidney disease
    • I. S. Lantinga-van Leeuwen, J. G. Dauwerse, H. J. Baelde et al., "Lowering of Pkd1 expression is sufcient to cause polycystic kidney disease," Human Molecular Genetics, vol. 13, no. 24, pp. 3069-3077, 2004.
    • (2004) Human Molecular Genetics , vol.13 , Issue.24 , pp. 3069-3077
    • Lantinga-Van Leeuwen, I.S.1    Dauwerse, J.G.2    Baelde, H.J.3
  • 24
    • 0030377075 scopus 로고    scopus 로고
    • Abdominal aortic aneurysms and autosomal dominant polycystic kidney disease
    • R. Torra, C. Nicolau, C. Badenas et al., "Abdominal aortic aneurysms and autosomal dominant polycystic kidney disease," Journal of the American Society of Nephrology, vol. 7, no. 11, pp. 2483-2486, 1996.
    • (1996) Journal of the American Society of Nephrology , vol.7 , Issue.11 , pp. 2483-2486
    • Torra, R.1    Nicolau, C.2    Badenas, C.3
  • 25
    • 0012376721 scopus 로고    scopus 로고
    • Cardiovascular disease in neurofbromatosis 1: Report of the NF1 Cardiovascular Task Force
    • J. M. Friedman, J. Arbiter, J. A. Epstein et al., "Cardiovascular disease in neurofbromatosis 1: report of the NF1 Cardiovascular Task Force," Genetics in Medicine, vol. 4, no. 3, pp. 105-111, 2002.
    • (2002) Genetics in Medicine , vol.4 , Issue.3 , pp. 105-111
    • Friedman, J.M.1    Arbiter, J.2    Epstein, J.A.3
  • 26
    • 84890414167 scopus 로고    scopus 로고
    • Ras-mek-erk signaling regulates Nf1 heterozygous neointima formation
    • B. K. Stansfeld, W. K. Bessler, R. Mali et al., "Ras-mek-erk signaling regulates Nf1 heterozygous neointima formation," American Journal of Pathology, vol. 184, no. 1, pp. 79-85, 2014.
    • (2014) American Journal of Pathology , vol.184 , Issue.1 , pp. 79-85
    • Stansfeld, B.K.1    Bessler, W.K.2    Mali, R.3
  • 27
    • 84897555473 scopus 로고    scopus 로고
    • Neurofbromin-defcient myeloid cells are critical mediators of aneurysm formation in vivo
    • F. Li, B. D. Downing, L. C. Smiley et al., "Neurofbromin-defcient myeloid cells are critical mediators of aneurysm formation in vivo," Circulation, vol. 129, no. 11, pp. 1213-1224, 2014.
    • (2014) Circulation , vol.129 , Issue.11 , pp. 1213-1224
    • Li, F.1    Downing, B.D.2    Smiley, L.C.3
  • 28
    • 0037049996 scopus 로고    scopus 로고
    • Fibulin-5 is an elastin-binding protein essential for elastic fbre development in vivo
    • H. Yanagisawa, E. C. Davist, B. C. Starcher et al., "Fibulin-5 is an elastin-binding protein essential for elastic fbre development in vivo," Nature, vol. 415, no. 6868, pp. 168-171, 2002.
    • (2002) Nature , vol.415 , Issue.6868 , pp. 168-171
    • Yanagisawa, H.1    Davist, E.C.2    Starcher, B.C.3
  • 29
    • 84973316206 scopus 로고    scopus 로고
    • Down-regulation of Fibulin-5 is associated with aortic dilation: Role of infamma-tion and epigenetics
    • M. Orriols, S. Varona, I. Martí-Pàmies et al., "Down-regulation of Fibulin-5 is associated with aortic dilation: role of infamma-tion and epigenetics," Cardiovascular Research, vol. 110, no. 3, pp. 431-442, 2016.
    • (2016) Cardiovascular Research , vol.110 , Issue.3 , pp. 431-442
    • Orriols, M.1    Varona, S.2    Martí-Pàmies, I.3
  • 30
    • 77949624933 scopus 로고    scopus 로고
    • Common polymorphisms of Fibulin-5 and the risk of abdominal aortic aneurysm development
    • S. A. Badger, C. V. Soong, M. E. O'Donnell, M. A. Sharif, R. R. Makar, and A. E. Hughes, "Common polymorphisms of Fibulin-5 and the risk of abdominal aortic aneurysm development," Vascular Medicine, vol. 15, no. 2, pp. 113-117, 2010.
    • (2010) Vascular Medicine , vol.15 , Issue.2 , pp. 113-117
    • Badger, S.A.1    Soong, C.V.2    O'Donnell, M.E.3    Sharif, M.A.4    Makar, R.R.5    Hughes, A.E.6
  • 31
    • 33646799108 scopus 로고    scopus 로고
    • Matrix metal-loproteinase 2 polymorphisms in a caucasian population with abdominal aortic aneurysm
    • I. Hinterseher, H. Bergert, E. Kuhlisch et al., "Matrix metal-loproteinase 2 polymorphisms in a caucasian population with abdominal aortic aneurysm," Journal of Surgical Research, vol. 133, no. 2, pp. 121-128, 2006.
    • (2006) Journal of Surgical Research , vol.133 , Issue.2 , pp. 121-128
    • Hinterseher, I.1    Bergert, H.2    Kuhlisch, E.3
  • 32
    • 52449116793 scopus 로고    scopus 로고
    • Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysm
    • L. Smallwood, R. Allcock, F. Van Bockxmeer et al., "Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysm," British Journal of Surgery, vol. 95, no. 10, pp. 1239-1244, 2008.
    • (2008) British Journal of Surgery , vol.95 , Issue.10 , pp. 1239-1244
    • Smallwood, L.1    Allcock, R.2    Van Bockxmeer, F.3
  • 33
    • 15944415451 scopus 로고    scopus 로고
    • MMP-12 has a role in abdominal aortic aneurysms in mice
    • G. M. Longo, S. J. Buda, N. Fiotta et al., "MMP-12 has a role in abdominal aortic aneurysms in mice," Surgery, vol. 137, no. 4, pp. 457-562, 2005.
    • (2005) Surgery , vol.137 , Issue.4 , pp. 457-562
    • Longo, G.M.1    Buda, S.J.2    Fiotta, N.3
  • 34
    • 36248988019 scopus 로고    scopus 로고
    • An increased frequency of the 5A allele in the promoter region of the MMP3 gene is associated with abdominal aortic aneurysms
    • J. Deguara, K. G. Burnand, J. Berg et al., "An increased frequency of the 5A allele in the promoter region of the MMP3 gene is associated with abdominal aortic aneurysms," Human Molecular Genetics, vol. 16, no. 24, pp. 3002-3007, 2007.
    • (2007) Human Molecular Genetics , vol.16 , Issue.24 , pp. 3002-3007
    • Deguara, J.1    Burnand, K.G.2    Berg, J.3
  • 35
    • 0037014614 scopus 로고    scopus 로고
    • Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease
    • N. Lamblin, C. Bauters, X. Hermant, J.-M. Lablanche, N. Helbecque, and P. Amouyel, "Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease," Journal of the American College of Cardiology, vol. 40, no. 1, pp. 43-48, 2002.
    • (2002) Journal of the American College of Cardiology , vol.40 , Issue.1 , pp. 43-48
    • Lamblin, N.1    Bauters, C.2    Hermant, X.3    Lablanche, J.-M.4    Helbecque, N.5    Amouyel, P.6
  • 36
    • 84945173643 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
    • M. J. Bown, G. T. Jones, S. C. Harrison et al., "Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1," The American Journal of Human Genetics, vol. 89, no. 5, pp. 619-627, 2011.
    • (2011) The American Journal of Human Genetics , vol.89 , Issue.5 , pp. 619-627
    • Bown, M.J.1    Jones, G.T.2    Harrison, S.C.3
  • 37
    • 84892385162 scopus 로고    scopus 로고
    • A variant in LDLR is associated with abdominal aortic aneurysm
    • D. T. Bradley, A. E. Hughes, S. A. Badger et al., "A variant in LDLR is associated with abdominal aortic aneurysm," Circulation: Cardiovascular Genetics, vol. 6, no. 5, pp. 498-504, 2013.
    • (2013) Circulation: Cardiovascular Genetics , vol.6 , Issue.5 , pp. 498-504
    • Bradley, D.T.1    Hughes, A.E.2    Badger, S.A.3
  • 38
    • 0034122352 scopus 로고    scopus 로고
    • Apolipoprotein e genotype is associated with differential expansion rates of small abdominal aortic aneurysms
    • L. U. Gerdes, J. S. Lindholt, S. Vammen, E. W. Henneberg, and H. Fasting, "Apolipoprotein E genotype is associated with differential expansion rates of small abdominal aortic aneurysms," British Journal of Surgery, vol. 87, no. 6, pp. 760-765, 2000.
    • (2000) British Journal of Surgery , vol.87 , Issue.6 , pp. 760-765
    • Gerdes, L.U.1    Lindholt, J.S.2    Vammen, S.3    Henneberg, E.W.4    Fasting, H.5
  • 40
    • 79956330132 scopus 로고    scopus 로고
    • Lessons on the pathogenesis of aneurysm from heritable conditions
    • M. E. Lindsay and H. C. Dietz, "Lessons on the pathogenesis of aneurysm from heritable conditions," Nature, vol. 473, no. 7347, pp. 308-316, 2011.
    • (2011) Nature , vol.473 , Issue.7347 , pp. 308-316
    • Lindsay, M.E.1    Dietz, H.C.2
  • 41
    • 22544451258 scopus 로고    scopus 로고
    • Giant aneurysms of the sinuses of Valsalva and aortic regurgitation in a patient with Noonan's syndrome
    • R. Purnell, I. Williams, U. Von Oppell, and A. Wood, "Giant aneurysms of the sinuses of Valsalva and aortic regurgitation in a patient with Noonan's syndrome," European Journal of Cardio-Toracic Surgery, vol. 28, no. 2, pp. 346-348, 2005.
    • (2005) European Journal of Cardio-Toracic Surgery , vol.28 , Issue.2 , pp. 346-348
    • Purnell, R.1    Williams, I.2    Von Oppell, U.3    Wood, A.4
  • 42
    • 84900457311 scopus 로고    scopus 로고
    • Hyperhomocysteinaemia, low folate concentrations and MTHFR C677T mutation in abdominal aortic aneurysm
    • H. Cao, X. Hu, Q. Zhang et al., "Hyperhomocysteinaemia, low folate concentrations and MTHFR C677T mutation in abdominal aortic aneurysm," Vasa-European Journal of Vascular Medicine, vol. 43, no. 3, pp. 181-188, 2014.
    • (2014) Vasa-European Journal of Vascular Medicine , vol.43 , Issue.3 , pp. 181-188
    • Cao, H.1    Hu, X.2    Zhang, Q.3
  • 43
    • 84988360805 scopus 로고    scopus 로고
    • Association between MTHFR C677T polymorphism and abdominal aortic aneurysm risk
    • Article ID e4793
    • J. Liu, X. Jia, H. Li et al., "Association between MTHFR C677T polymorphism and abdominal aortic aneurysm risk," Medicine, vol. 95, no. 36, Article ID e4793, 2016.
    • (2016) Medicine , vol.95 , Issue.36
    • Liu, J.1    Jia, X.2    Li, H.3
  • 44
    • 33645410305 scopus 로고    scopus 로고
    • Methylenetetrahydro-folate reductase mutation in subjects with abdominal aortic aneurysm subdivided for age
    • F. Ferrara, S. Novo, S. Grimaudo et al., "Methylenetetrahydro-folate reductase mutation in subjects with abdominal aortic aneurysm subdivided for age," Clinical Hemorheology and Microcirculation, vol. 34, no. 3, pp. 421-426, 2006.
    • (2006) Clinical Hemorheology and Microcirculation , vol.34 , Issue.3 , pp. 421-426
    • Ferrara, F.1    Novo, S.2    Grimaudo, S.3
  • 46
    • 4644301666 scopus 로고    scopus 로고
    • The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm
    • L. Zhao, M. P. W. Moos, R. Gräbner et al., "Te 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm," Nature Medicine, vol. 10, no. 9, pp. 966-973, 2004.
    • (2004) Nature Medicine , vol.10 , Issue.9 , pp. 966-973
    • Zhao, L.1    Moos, M.P.W.2    Gräbner, R.3
  • 47
    • 84930662117 scopus 로고    scopus 로고
    • The potential role of DNA methylation in abdominal aortic aneurysms
    • E. J. Ryer, K. E. Ronning, R. Erdman et al., "Te potential role of DNA methylation in abdominal aortic aneurysms," International Journal of Molecular Sciences, vol. 16, no. 5, pp. 11259-11275, 2015.
    • (2015) International Journal of Molecular Sciences , vol.16 , Issue.5 , pp. 11259-11275
    • Ryer, E.J.1    Ronning, K.E.2    Erdman, R.3
  • 48
    • 84857491474 scopus 로고    scopus 로고
    • MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion
    • Article ID 122ra22
    • L. Maegdefessel, J. Azuma, R. Toh et al., "MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion," Science Translational Medicine, vol. 4, no. 122, Article ID 122ra22, 2012.
    • (2012) Science Translational Medicine , vol.4 , Issue.122
    • Maegdefessel, L.1    Azuma, J.2    Toh, R.3
  • 49
    • 84856552278 scopus 로고    scopus 로고
    • Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development
    • L. Maegdefessel, J. Azuma, R. Toh et al., "Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development," The Journal of Clinical Investigation, vol. 122, no. 2, pp. 497-506, 2012.
    • (2012) The Journal of Clinical Investigation , vol.122 , Issue.2 , pp. 497-506
    • Maegdefessel, L.1    Azuma, J.2    Toh, R.3
  • 50
    • 84856029029 scopus 로고    scopus 로고
    • MiR-29b participates in early aneurysm development in Marfan syndrome
    • D. R. Merk, J. T. Chin, B. A. Dake et al., "miR-29b participates in early aneurysm development in Marfan syndrome," Circulation Research, vol. 110, no. 2, pp. 312-324, 2012.
    • (2012) Circulation Research , vol.110 , Issue.2 , pp. 312-324
    • Merk, D.R.1    Chin, J.T.2    Dake, B.A.3
  • 53
    • 33747812887 scopus 로고    scopus 로고
    • Aneurysm syndromes caused by mutations in the TGF-α receptor
    • B. L. Loeys, U. Schwarze, T. Holm et al., "Aneurysm syndromes caused by mutations in the TGF-α receptor," New England Journal of Medicine, vol. 355, no. 8, pp. 788-798, 2006.
    • (2006) New England Journal of Medicine , vol.355 , Issue.8 , pp. 788-798
    • Loeys, B.L.1    Schwarze, U.2    Holm, T.3
  • 55
    • 23044438103 scopus 로고    scopus 로고
    • Mutations in transforming growth factor-α receptor type II cause familial thoracic aortic aneurysms and dissections
    • H. Pannu, V. T. Fadulu, J. Chang et al., "Mutations in transforming growth factor-α receptor type II cause familial thoracic aortic aneurysms and dissections," Circulation, vol. 112, no. 4, pp. 513-520, 2005.
    • (2005) Circulation , vol.112 , Issue.4 , pp. 513-520
    • Pannu, H.1    Fadulu, V.T.2    Chang, J.3
  • 56
    • 84881662678 scopus 로고    scopus 로고
    • Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections
    • D.-C. Guo, E. Regalado, D. E. Casteel et al., "Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections," American Journal of Human Genetics, vol. 93, no. 2, pp. 398-404, 2013.
    • (2013) American Journal of Human Genetics , vol.93 , Issue.2 , pp. 398-404
    • Guo, D.-C.1    Regalado, E.2    Casteel, D.E.3
  • 57
    • 79952779871 scopus 로고    scopus 로고
    • Familial thoracic aortic aneurysms and dissections identification of a novel locus for stable aneurysms with a low risk for progression to aortic dissection
    • D.-C. Guo, E. S. Regalado, C. Minn et al., "Familial thoracic aortic aneurysms and dissections identification of a novel locus for stable aneurysms with a low risk for progression to aortic dissection," Circulation: Cardiovascular Genetics, vol. 4, no. 1, pp. 36-42, 2011.
    • (2011) Circulation: Cardiovascular Genetics , vol.4 , Issue.1 , pp. 36-42
    • Guo, D.-C.1    Regalado, E.S.2    Minn, C.3
  • 58
    • 84959904216 scopus 로고    scopus 로고
    • FOXE3 mutations predispose to thoracic aortic aneurysms and dissections
    • S.-Q. Kuang, O. Medina-Martinez, D.-C. Guo et al., "FOXE3 mutations predispose to thoracic aortic aneurysms and dissections," The Journal of Clinical Investigation, vol. 126, no. 3, pp. 948-961, 2016.
    • (2016) The Journal of Clinical Investigation , vol.126 , Issue.3 , pp. 948-961
    • Kuang, S.-Q.1    Medina-Martinez, O.2    Guo, D.-C.3
  • 59
    • 84860396524 scopus 로고    scopus 로고
    • Autoso-mal dominant inheritance of a predisposition to thoracic aortic aneurysms and dissections and intracranial saccular aneurysms
    • E. Regalado, S. Medrek, V. Tran-Fadulu et al., "Autoso-mal dominant inheritance of a predisposition to thoracic aortic aneurysms and dissections and intracranial saccular aneurysms," American Journal of Medical Genetics A, vol. 155, no. 9, pp. 2125-2130, 2011.
    • (2011) American Journal of Medical Genetics A , vol.155 , Issue.9 , pp. 2125-2130
    • Regalado, E.1    Medrek, S.2    Tran-Fadulu, V.3
  • 60
    • 84871333396 scopus 로고
    • Toracic aortic aneurysms and aortic dissections
    • R. A. Pagon, M. P. Adam, H. H. Ardinger et al., Eds., University of Washington, Seattle, Wash, USA
    • D. M. Milewicz and E. Regalado, "Toracic aortic aneurysms and aortic dissections," in GeneReviews®, R. A. Pagon, M. P. Adam, H. H. Ardinger et al., Eds., University of Washington, Seattle, Wash, USA, 1993.
    • (1993) GeneReviews®
    • Milewicz, D.M.1    Regalado, E.2
  • 61
    • 84924018358 scopus 로고    scopus 로고
    • Use of genetics for personalized management of heritable thoracic aortic disease: How do we get there?
    • D. M. Milewicz and E. S. Regalado, "Use of genetics for personalized management of heritable thoracic aortic disease: how do we get there?" The Journal of Toracic and Cardiovascular Surgery, vol. 149, no. 2, pp. S3-S5, 2015.
    • (2015) The Journal of Toracic and Cardiovascular Surgery , vol.149 , Issue.2 , pp. S3-S5
    • Milewicz, D.M.1    Regalado, E.S.2
  • 62
    • 0026743940 scopus 로고
    • Intracranial aneurysms in autosomal dominant polycystic kidney disease
    • A. B. Chapman, D. Rubinstein, R. Hughes et al., "Intracranial aneurysms in autosomal dominant polycystic kidney disease," The New England Journal of Medicine, vol. 327, no. 13, pp. 916-920,1992.
    • (1992) The New England Journal of Medicine , vol.327 , Issue.13 , pp. 916-920
    • Chapman, A.B.1    Rubinstein, D.2    Hughes, R.3
  • 63
    • 67049114683 scopus 로고    scopus 로고
    • Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease
    • T. Ecder and R. W. Schrier, "Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease," Nature Reviews Nephrology, vol. 5, no. 4, pp. 221-228, 2009.
    • (2009) Nature Reviews Nephrology , vol.5 , Issue.4 , pp. 221-228
    • Ecder, T.1    Schrier, R.W.2
  • 64
    • 35148840431 scopus 로고    scopus 로고
    • Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model
    • S. Hassane, N. Claij, I. S. Lantinga-van Leeuwen et al., "Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model," Arteriosclerosis, Trombosis, and Vascular Biology, vol. 27, no. 10, pp. 2177-2183, 2007
    • (2007) Arteriosclerosis, Trombosis, and Vascular Biology , vol.27 , Issue.10 , pp. 2177-2183
    • Hassane, S.1    Claij, N.2    Lantinga-Van Leeuwen, I.S.3
  • 66
    • 77949897640 scopus 로고    scopus 로고
    • Association study of single nucleotide polymorphisms on chromosome 19q13 with abdominal aortic aneurysm
    • A. F. Baas, J. Medic, R. van't Slot et al., "Association study of single nucleotide polymorphisms on chromosome 19q13 with abdominal aortic aneurysm," Angiology, vol. 61, no. 3, pp. 243-247, 2010.
    • (2010) Angiology , vol.61 , Issue.3 , pp. 243-247
    • Baas, A.F.1    Medic, J.2    Van'T Slot, R.3
  • 67
    • 66149112940 scopus 로고    scopus 로고
    • Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association
    • J. R. Elmore, M. A. Obmann, H. Kuivaniemi et al., "Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association," Journal of Vascular Surgery, vol. 49, no. 6, pp. 1525-1531, 2009.
    • (2009) Journal of Vascular Surgery , vol.49 , Issue.6 , pp. 1525-1531
    • Elmore, J.R.1    Obmann, M.A.2    Kuivaniemi, H.3
  • 68
    • 84947899513 scopus 로고    scopus 로고
    • Genome-wide association study identifes a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
    • S. Gretarsdottir, A. F. Baas, G Torleifsson et al., "Genome-wide association study identifes a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm," Nature Genetics, vol. 42, no. 8, pp. 692-697, 2010.
    • (2010) Nature Genetics , vol.42 , Issue.8 , pp. 692-697
    • Gretarsdottir, S.1    Baas, A.F.2    Torleifsson, G.3
  • 69
    • 66849122587 scopus 로고    scopus 로고
    • Pathogenic FBN1 mutations in 146 adults not meeting clinical diagnostic criteria for marfan syndrome: Further delineation of type 1 fbrillinopathies and focus on patients with an isolated major criterion
    • L. Faivre, G Collod-Beroud, B. Callewaert et al., "Pathogenic FBN1 mutations in 146 adults not meeting clinical diagnostic criteria for marfan syndrome: further delineation of type 1 fbrillinopathies and focus on patients with an isolated major criterion," American Journal of Medical Genetics, Part A, vol. 149, no. 5, pp. 854-860, 2009.
    • (2009) American Journal of Medical Genetics, Part A , vol.149 , Issue.5 , pp. 854-860
    • Faivre, L.1    Collod-Beroud, G.2    Callewaert, B.3
  • 70
    • 0036713921 scopus 로고    scopus 로고
    • Homozygosity for a missense mutation in fbulin-5 (FBLN5) results in a severe form of cutis laxa
    • B. Loeys, L. Van Maldergem, G. Mortier et al., "Homozygosity for a missense mutation in fbulin-5 (FBLN5) results in a severe form of cutis laxa," Human Molecular Genetics, vol. 11, no. 18, pp. 2113-2118, 2002.
    • (2002) Human Molecular Genetics , vol.11 , Issue.18 , pp. 2113-2118
    • Loeys, B.1    Van Maldergem, L.2    Mortier, G.3
  • 71
    • 84908290110 scopus 로고    scopus 로고
    • Fibulin-4 and fbulin-5 in elastogenesis and beyond: Insights from mouse and human studies
    • C. L. Papke and H. Yanagisawa, "Fibulin-4 and fbulin-5 in elastogenesis and beyond: insights from mouse and human studies," Matrix Biology, vol. 37, pp. 142-149, 2014.
    • (2014) Matrix Biology , vol.37 , pp. 142-149
    • Papke, C.L.1    Yanagisawa, H.2
  • 72
    • 0027185655 scopus 로고
    • Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome
    • A. K. Ewart, C. A. Morris, D. Atkinson et al., "Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome," Nature Genetics, vol. 5, no. 1, pp. 11-16,1993.
    • (1993) Nature Genetics , vol.5 , Issue.1 , pp. 11-16
    • Ewart, A.K.1    Morris, C.A.2    Atkinson, D.3
  • 74
    • 0037155832 scopus 로고    scopus 로고
    • Increased MMP-2 expression in connective tissue growth factor over-expression vascular smooth muscle cells
    • W.-H. Fan and M. J. Karnovsky, "Increased MMP-2 expression in connective tissue growth factor over-expression vascular smooth muscle cells," The Journal of Biological Chemistry, vol. 277, no. 12, pp. 9800-9805, 2002.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.12 , pp. 9800-9805
    • Fan, W.-H.1    Karnovsky, M.J.2
  • 78
    • 0342872046 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: A role for CD40 signaling in plaque rupture?
    • U. Schönbeck, F. Mach, G. K. Sukhova et al., "Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?" Circulation Research, vol. 81, no. 3, pp. 448-454, 1997.
    • (1997) Circulation Research , vol.81 , Issue.3 , pp. 448-454
    • Schönbeck, U.1    Mach, F.2    Sukhova, G.K.3
  • 79
    • 0030824354 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta
    • N. A. Tamarina, W. D. McMillan, V. P. Shively, and W. H. Pearce, "Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta," Surgery, vol. 122, no. 2, pp. 264-272, 1997.
    • (1997) Surgery , vol.122 , Issue.2 , pp. 264-272
    • Tamarina, N.A.1    McMillan, W.D.2    Shively, V.P.3    Pearce, W.H.4
  • 80
    • 34547902858 scopus 로고    scopus 로고
    • Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms
    • M. Folkesson, M. Kazi, C. Zhu et al., "Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms," Trombo-sis and Haemostasis, vol. 98, no. 2, pp. 427-433, 2007.
    • (2007) Trombo-sis and Haemostasis , vol.98 , Issue.2 , pp. 427-433
    • Folkesson, M.1    Kazi, M.2    Zhu, C.3
  • 81
  • 82
    • 0037373277 scopus 로고    scopus 로고
    • Dysregula-tion of TGF-α activation contributes to pathogenesis in Marfan syndrome
    • E. R. Neptune, P. A. Frischmeyer, D. E. Arking et al., "Dysregula-tion of TGF-α activation contributes to pathogenesis in Marfan syndrome," Nature Genetics, vol. 33, no. 3, pp. 407-411, 2003.
    • (2003) Nature Genetics , vol.33 , Issue.3 , pp. 407-411
    • Neptune, E.R.1    Frischmeyer, P.A.2    Arking, D.E.3
  • 83
    • 84880795141 scopus 로고    scopus 로고
    • Genetics of thoracic aortic aneurysm: At the crossroad of transforming growth factor-α signaling and vascular smooth muscle cell contractility
    • E. Gillis, L. Van Laer, and B. L. Loeys, "Genetics of thoracic aortic aneurysm: at the crossroad of transforming growth factor-α signaling and vascular smooth muscle cell contractility," Circulation Research, vol. 113, no. 3, pp. 327-340, 2013.
    • (2013) Circulation Research , vol.113 , Issue.3 , pp. 327-340
    • Gillis, E.1    Van Laer, L.2    Loeys, B.L.3
  • 84
    • 33645672459 scopus 로고    scopus 로고
    • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
    • J. P. Habashi, D. P. Judge, T. M. Holm et al., "Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome," Science, vol. 312, no. 5770, pp. 117-121, 2006.
    • (2006) Science , vol.312 , Issue.5770 , pp. 117-121
    • Habashi, J.P.1    Judge, D.P.2    Holm, T.M.3
  • 85
    • 79954579275 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    • J. P. Habashi, J. J. Doyle, T. M. Holm et al., "Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism," Science, vol. 332, no. 6027, pp. 361-365, 2011.
    • (2011) Science , vol.332 , Issue.6027 , pp. 361-365
    • Habashi, J.P.1    Doyle, J.J.2    Holm, T.M.3
  • 86
    • 79954625123 scopus 로고    scopus 로고
    • Noncanonical TGFα signaling contributes to aortic aneurysm progression in marfan syndrome mice
    • T. M. Holm, J. P. Habashi, J. J. Doyle et al., "Noncanonical TGFα signaling contributes to aortic aneurysm progression in marfan syndrome mice," Science, vol. 332, no. 6027, pp. 358-361, 2011.
    • (2011) Science , vol.332 , Issue.6027 , pp. 358-361
    • Holm, T.M.1    Habashi, J.P.2    Doyle, J.J.3
  • 88
    • 76649122801 scopus 로고    scopus 로고
    • TGF-α activity protects against infammatory aortic aneurysm progression and complications in angiotensin II-infused mice
    • Y. Wang, H. Ait-Oufella, O. Herbin et al., "TGF-α activity protects against infammatory aortic aneurysm progression and complications in angiotensin II-infused mice," The Journal of Clinical Investigation, vol. 120, no. 2, pp. 422-432, 2010.
    • (2010) The Journal of Clinical Investigation , vol.120 , Issue.2 , pp. 422-432
    • Wang, Y.1    Ait-Oufella, H.2    Herbin, O.3
  • 89
    • 84910667380 scopus 로고    scopus 로고
    • Disruption of TGF-α signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm
    • F. Gao, P. Chambon, S. Ofermanns et al., "Disruption of TGF-α signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm," Biochemical and Biophysical Research Communications, vol. 454, no. 1, pp. 137-143, 2014.
    • (2014) Biochemical and Biophysical Research Communications , vol.454 , Issue.1 , pp. 137-143
    • Gao, F.1    Chambon, P.2    Ofermanns, S.3
  • 90
    • 79952118192 scopus 로고    scopus 로고
    • Role of TGFα in a model of abdominal aortic aneurysm in mice
    • H. Ait-Oufella, Y. Wang, O. Herbin, A. Tedgui, and Z. Mallat, "Role of TGFα in a model of abdominal aortic aneurysm in mice," M édecine Science, vol. 26, no. 10, pp. 795-797, 2010.
    • (2010) M Édecine Science , vol.26 , Issue.10 , pp. 795-797
    • Ait-Oufella, H.1    Wang, Y.2    Herbin, O.3    Tedgui, A.4    Mallat, Z.5
  • 91
    • 57649143132 scopus 로고    scopus 로고
    • ACE and TGFBR1 genes interact in infuencing the susceptibility to abdominal aortic aneurysm
    • L. Lucarini, E. Sticchi, F. Sof et al., "ACE and TGFBR1 genes interact in infuencing the susceptibility to abdominal aortic aneurysm," Atherosclerosis, vol. 202, no. 1, pp. 205-210, 2009.
    • (2009) Atherosclerosis , vol.202 , Issue.1 , pp. 205-210
    • Lucarini, L.1    Sticchi, E.2    Sof, F.3
  • 92
    • 0032968645 scopus 로고    scopus 로고
    • Differential regulation of transforming growth factor receptors by angiotensin II and transforming growth factor-α1 in vascular smooth muscle
    • A. Siegert, E. Ritz, S. Orth, and J. Wagner, "Differential regulation of transforming growth factor receptors by angiotensin II and transforming growth factor-α1 in vascular smooth muscle," Journal of Molecular Medicine, vol. 77, no. 5, pp. 437-445, 1999.
    • (1999) Journal of Molecular Medicine , vol.77 , Issue.5 , pp. 437-445
    • Siegert, A.1    Ritz, E.2    Orth, S.3    Wagner, J.4
  • 93
    • 0034051005 scopus 로고    scopus 로고
    • Angiotensin II upregulates transforming growth factor-α type i receptor on rat vascular smooth muscle cells
    • N. Fukuda, W.-Y. Hu, A. Kubo et al., "Angiotensin II upregulates transforming growth factor-α type I receptor on rat vascular smooth muscle cells," American Journal of Hypertension, vol. 13, no. 2, pp. 191-198, 2000.
    • (2000) American Journal of Hypertension , vol.13 , Issue.2 , pp. 191-198
    • Fukuda, N.1    Hu, W.-Y.2    Kubo, A.3
  • 94
    • 36348932689 scopus 로고    scopus 로고
    • Investigation of the MYH11 gene in sporadic patients with an isolated persistently patent arterial duct
    • L. Zhu, D. Bonnet, M. Boussion, B. Vedie, D. Sidi, and X. Jeunemaitre, "Investigation of the MYH11 gene in sporadic patients with an isolated persistently patent arterial duct," Cardiology in the Young, vol. 17, no. 6, pp. 666-672, 2007.
    • (2007) Cardiology in the Young , vol.17 , Issue.6 , pp. 666-672
    • Zhu, L.1    Bonnet, D.2    Boussion, M.3    Vedie, B.4    Sidi, D.5    Jeunemaitre, X.6
  • 95
    • 33947679772 scopus 로고    scopus 로고
    • Mechanisms of disease: Genetic causes of familial hypercholesterolemia
    • A. K. Soutar and R. P. Naoumova, "Mechanisms of disease: genetic causes of familial hypercholesterolemia," Nature Clinical Practice Cardiovascular Medicine, vol. 4, no. 4, pp. 214-225, 2007.
    • (2007) Nature Clinical Practice Cardiovascular Medicine , vol.4 , Issue.4 , pp. 214-225
    • Soutar, A.K.1    Naoumova, R.P.2
  • 96
    • 84907152295 scopus 로고    scopus 로고
    • Genomic insights into abdominal aortic aneu-rysms
    • M. J. Bown, "Genomic insights into abdominal aortic aneu-rysms," Annals of the Royal College of Surgeons of England, vol. 96, no. 6, pp. 405-414, 2014.
    • (2014) Annals of the Royal College of Surgeons of England , vol.96 , Issue.6 , pp. 405-414
    • Bown, M.J.1
  • 98
    • 0033814562 scopus 로고    scopus 로고
    • Estimation of apolipoprotein e genotype-specifc relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: Apolipoprotein e gene is a 'frailty gene,' not a 'longevity gene'
    • L. U. Gerdes, B. Jeune, K. A. Ranberg, H. Nybo, and J. W. Vaupel, "Estimation of apolipoprotein E genotype-specifc relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a 'frailty gene,' not a 'longevity gene'," Genetic Epidemiology, vol. 19, no. 3, pp. 202-210, 2000.
    • (2000) Genetic Epidemiology , vol.19 , Issue.3 , pp. 202-210
    • Gerdes, L.U.1    Jeune, B.2    Ranberg, K.A.3    Nybo, H.4    Vaupel, J.W.5
  • 99
    • 78249260007 scopus 로고    scopus 로고
    • Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: Two nationwide cohort studies
    • R. Jacobsen, T. Martinussen, L. Christiansen et al., "Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies," Aging Cell, vol. 9, no. 6, pp. 1004-1009, 2010.
    • (2010) Aging Cell , vol.9 , Issue.6 , pp. 1004-1009
    • Jacobsen, R.1    Martinussen, T.2    Christiansen, L.3
  • 100
    • 0025369709 scopus 로고
    • Deletions and a translocation interrupt a cloned gene at the neurofbromatosis type 1 locus
    • D. Viskochil, A. M. Buchberg, G. Xu et al., "Deletions and a translocation interrupt a cloned gene at the neurofbromatosis type 1 locus," Cell, vol. 62, no. 1, pp. 187-192, 1990.
    • (1990) Cell , vol.62 , Issue.1 , pp. 187-192
    • Viskochil, D.1    Buchberg, A.M.2    Xu, G.3
  • 101
    • 84974686570 scopus 로고    scopus 로고
    • Neurofbromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans
    • W. K. Bessler, F. Z. Hudson, H. Zhang et al., "Neurofbromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans," Free Radical Biology & Medicine, vol. 97, pp. 212-222, 2016.
    • (2016) Free Radical Biology & Medicine , vol.97 , pp. 212-222
    • Bessler, W.K.1    Hudson, F.Z.2    Zhang, H.3
  • 102
    • 84960124044 scopus 로고    scopus 로고
    • +/- mono-cytes/macrophages induce neointima formation via CCR2 activation
    • +/- mono-cytes/macrophages induce neointima formation via CCR2 activation," Human Molecular Genetics, vol. 25, no. 6, pp. 1129-1139, 2016.
    • (2016) Human Molecular Genetics , vol.25 , Issue.6 , pp. 1129-1139
    • Bessler, W.K.1    Kim, G.2    Hudson, F.Z.3
  • 103
    • 84873416941 scopus 로고    scopus 로고
    • Heterozygous inac-tivation of the NF1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway
    • B. K. Stansfeld, W. K. Bessler, R. Mali et al., "Heterozygous inac-tivation of the NF1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway," Human Molecular Genetics, vol. 22, no. 5, pp. 977-988, 2013.
    • (2013) Human Molecular Genetics , vol.22 , Issue.5 , pp. 977-988
    • Stansfeld, B.K.1    Bessler, W.K.2    Mali, R.3
  • 104
    • 0026048268 scopus 로고
    • Watson syndrome: Is it a subtype of type 1 neurofbromatosis?
    • J. E. Allanson, M. Upadhyaya, G. H. Watson et al., "Watson syndrome: is it a subtype of type 1 neurofbromatosis?" Journal of Medical Genetics, vol. 28, no. 11, pp. 752-756, 1991.
    • (1991) Journal of Medical Genetics , vol.28 , Issue.11 , pp. 752-756
    • Allanson, J.E.1    Upadhyaya, M.2    Watson, G.H.3
  • 105
    • 34548511992 scopus 로고    scopus 로고
    • Vascular abnormalities in patients with neurofbromatosis syndrome type I: Clinical spectrum, management, and results
    • G. S. Oderich, T. M. Sullivan, T. C. Bower et al., "Vascular abnormalities in patients with neurofbromatosis syndrome type I: clinical spectrum, management, and results," Journal of Vascular Surgery, vol. 46, no. 3, pp. 475-484, 2007.
    • (2007) Journal of Vascular Surgery , vol.46 , Issue.3 , pp. 475-484
    • Oderich, G.S.1    Sullivan, T.M.2    Bower, T.C.3
  • 106
    • 70349257973 scopus 로고    scopus 로고
    • Cerebral arteri-opathy in children with neurofbromatosis type 1
    • D. Rea, J. F. Brandsema, D. Armstrong et al., "Cerebral arteri-opathy in children with neurofbromatosis type 1," Pediatrics, vol. 124, no. 3, pp. e476-e483, 2009.
    • (2009) Pediatrics , vol.124 , Issue.3 , pp. e476-e483
    • Rea, D.1    Brandsema, J.F.2    Armstrong, D.3
  • 107
    • 0033930510 scopus 로고    scopus 로고
    • Renovascular disease and hypertension in children with neurofbromatosis
    • E. Fossali, E. Signorini, R. C. Intermite et al., "Renovascular disease and hypertension in children with neurofbromatosis," Pediatric Nephrology, vol. 14, no. 8-9, pp. 806-810, 2000.
    • (2000) Pediatric Nephrology , vol.14 , Issue.8-9 , pp. 806-810
    • Fossali, E.1    Signorini, E.2    Intermite, R.C.3
  • 108
    • 0028788570 scopus 로고
    • Vascular system defects and neuronal apoptosis in mice lacking Ras GTPase-activating protein
    • M. Henkemeyer, D. J. Rossi, D. P. Holmyard et al., "Vascular system defects and neuronal apoptosis in mice lacking Ras GTPase-activating protein," Nature, vol. 377, no. 6551, pp. 695-701, 1995.
    • (1995) Nature , vol.377 , Issue.6551 , pp. 695-701
    • Henkemeyer, M.1    Rossi, D.J.2    Holmyard, D.P.3
  • 109
    • 13244281559 scopus 로고    scopus 로고
    • Cerebrovascular abnormalities in a population of children with neurofbromato-sis type 1
    • T. L. Rosser, G. Vezina, and R. J. Packer, "Cerebrovascular abnormalities in a population of children with neurofbromato-sis type 1," Neurology, vol. 64, no. 3, pp. 553-555, 2005.
    • (2005) Neurology , vol.64 , Issue.3 , pp. 553-555
    • Rosser, T.L.1    Vezina, G.2    Packer, R.J.3
  • 110
    • 11844295380 scopus 로고    scopus 로고
    • Matrix metal-loproteinases in ascending aortic aneurysms: Bicuspid versus trileafet aortic valves
    • S. A. Lemaire, X. Wang, J. A. Wilks et al., "Matrix metal-loproteinases in ascending aortic aneurysms: bicuspid versus trileafet aortic valves," Journal of Surgical Research, vol. 123, no. 1, pp. 40-48, 2005.
    • (2005) Journal of Surgical Research , vol.123 , Issue.1 , pp. 40-48
    • Lemaire, S.A.1    Wang, X.2    Wilks, J.A.3
  • 111
    • 0030867553 scopus 로고    scopus 로고
    • Size matters: The relationship between MMP-9 expression and aortic diameter
    • W. D. McMillan, N. A. Tamarina, M. Cipollone, D. A. Johnson, M. A. Parker, and W. H. Pearce, "Size matters: the relationship between MMP-9 expression and aortic diameter," Circulation, vol. 96, no. 7, pp. 2228-2232, 1997.
    • (1997) Circulation , vol.96 , Issue.7 , pp. 2228-2232
    • McMillan, W.D.1    Tamarina, N.A.2    Cipollone, M.3    Johnson, D.A.4    Parker, M.A.5    Pearce, W.H.6
  • 112
    • 84930243436 scopus 로고    scopus 로고
    • Divergent roles of matrix met-alloproteinase 2 in pathogenesis of thoracic aortic aneurysm
    • M. Shen, J. Lee, R. Basu et al., "Divergent roles of matrix met-alloproteinase 2 in pathogenesis of thoracic aortic aneurysm," Arteriosclerosis, Trombosis, and Vascular Biology, vol. 35, no. 4, pp. 888-898, 2015.
    • (2015) Arteriosclerosis, Trombosis, and Vascular Biology , vol.35 , Issue.4 , pp. 888-898
    • Shen, M.1    Lee, J.2    Basu, R.3
  • 113
    • 84892594857 scopus 로고    scopus 로고
    • Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells
    • S. Zhang, B. Zhong, M. Chen et al., "Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells," International Journal of Cancer, vol. 134, no. 7, pp. 1583-1594, 2014.
    • (2014) International Journal of Cancer , vol.134 , Issue.7 , pp. 1583-1594
    • Zhang, S.1    Zhong, B.2    Chen, M.3
  • 114
    • 34247145010 scopus 로고    scopus 로고
    • Impact of infammation on epigenetic DNA methylation-a novel risk factor for cardiovascular disease?
    • P. Stenvinkel, M. Karimi, S. Johansson et al., "Impact of infammation on epigenetic DNA methylation-a novel risk factor for cardiovascular disease?" Journal of Internal Medicine, vol. 261, no. 5, pp. 488-499, 2007.
    • (2007) Journal of Internal Medicine , vol.261 , Issue.5 , pp. 488-499
    • Stenvinkel, P.1    Karimi, M.2    Johansson, S.3
  • 115
    • 84949116610 scopus 로고    scopus 로고
    • New insights into the impact of neuro-infammation in rheumatoid arthritis
    • Article 357
    • N. R. Fuggle, F. A. Howe, R. Allen, and N. Sofat, "New insights into the impact of neuro-infammation in rheumatoid arthritis," Frontiers in Neuroscience, vol. 8, article 357, 2014.
    • (2014) Frontiers in Neuroscience , vol.8
    • Fuggle, N.R.1    Howe, F.A.2    Allen, R.3    Sofat, N.4
  • 116
    • 84930068573 scopus 로고    scopus 로고
    • Fibronectin afects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines
    • Article ID e105806
    • I. T. Pereira, E. A. S. Ramos, E. T. Costa et al., "Fibronectin afects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines," PLoS ONE, vol. 9, no. 9, Article ID e105806, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.9
    • Pereira, I.T.1    Ramos, E.A.S.2    Costa, E.T.3
  • 117
    • 0036401604 scopus 로고    scopus 로고
    • Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression
    • M. Ailenberg and M. Silverman, "Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression," Biochemical and Biophysical Research Communications, vol. 298, no. 1, pp. 110-115, 2002.
    • (2002) Biochemical and Biophysical Research Communications , vol.298 , Issue.1 , pp. 110-115
    • Ailenberg, M.1    Silverman, M.2
  • 118
    • 84929507615 scopus 로고    scopus 로고
    • DNA demethylation at the promoter region enhances the expression of MMP-9 in ectopic endometrial stromal cells of endometriosis
    • C. Yuan, L. Zhang, Y. Gao, D. Peng, J. Liu, and Y. Cai, "DNA demethylation at the promoter region enhances the expression of MMP-9 in ectopic endometrial stromal cells of endometriosis," Chinese Journal of Cellular and Molecular Immunology, vol. 30, no. 12, pp. 1258-1261, 2014.
    • (2014) Chinese Journal of Cellular and Molecular Immunology , vol.30 , Issue.12 , pp. 1258-1261
    • Yuan, C.1    Zhang, L.2    Gao, Y.3    Peng, D.4    Liu, J.5    Cai, Y.6
  • 119
    • 4644354120 scopus 로고    scopus 로고
    • Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression
    • S. Nozell, Z. Ma, C. Wilson, R. Shah, and E. N. Benveniste, "Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression," The Journal of Biological Chemistry, vol. 279, no. 37, pp. 38577-38589, 2004.
    • (2004) The Journal of Biological Chemistry , vol.279 , Issue.37 , pp. 38577-38589
    • Nozell, S.1    Ma, Z.2    Wilson, C.3    Shah, R.4    Benveniste, E.N.5
  • 120
    • 0037462727 scopus 로고    scopus 로고
    • Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation
    • C. Yan, H. Wang, Y. Toh, and D. D. Boyd, "Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation," The Journal of Biological Chemistry, vol. 278, no. 4, pp. 2309-2316, 2003.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.4 , pp. 2309-2316
    • Yan, C.1    Wang, H.2    Toh, Y.3    Boyd, D.D.4
  • 121
    • 84966560292 scopus 로고    scopus 로고
    • Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: Therapeutic potential of HDAC inhibitors
    • M. Galán, S. Varona, M. Orriols et al., "Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors," Disease Models and Mechanisms, vol. 9, no. 5, pp. 541-552, 2016.
    • (2016) Disease Models and Mechanisms , vol.9 , Issue.5 , pp. 541-552
    • Galán, M.1    Varona, S.2    Orriols, M.3
  • 122
    • 40749083602 scopus 로고    scopus 로고
    • A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-defcient mice
    • A. Vinh, T. A. Gaspari, H. B. Liu, L. F. Dousha, R. E. Wid-dop, and A. E. Dear, "A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-defcient mice," Journal of Vascular Research, vol. 45, no. 2, pp. 143-152, 2008.
    • (2008) Journal of Vascular Research , vol.45 , Issue.2 , pp. 143-152
    • Vinh, A.1    Gaspari, T.A.2    Liu, H.B.3    Dousha, L.F.4    Wid-Dop, R.E.5    Dear, A.E.6
  • 123
    • 0033823312 scopus 로고    scopus 로고
    • High prevalence of mild hyperhomocysteinemia in patients with abdominal aortic aneurysm
    • T. Brunelli, D. Prisco, S. Fedi et al., "High prevalence of mild hyperhomocysteinemia in patients with abdominal aortic aneurysm," Journal of Vascular Surgery, vol. 32, no. 3, pp. 531-536, 2000.
    • (2000) Journal of Vascular Surgery , vol.32 , Issue.3 , pp. 531-536
    • Brunelli, T.1    Prisco, D.2    Fedi, S.3
  • 124
    • 84958522192 scopus 로고    scopus 로고
    • Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han population
    • Article ID 17966
    • J. Liu, S. W. Zuo, Y. Li et al., "Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han population," Scientific Reports, vol. 6, Article ID 17966, 2016.
    • (2016) Scientific Reports , vol.6
    • Liu, J.1    Zuo, S.W.2    Li, Y.3
  • 126
    • 84878107564 scopus 로고    scopus 로고
    • The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation
    • S. M. Krishna, A. Dear, J. M. Craig, P. E. Norman, and J. Golledge, "Te potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation," Atherosclerosis, vol. 228, no. 2, pp. 295-305, 2013.
    • (2013) Atherosclerosis , vol.228 , Issue.2 , pp. 295-305
    • Krishna, S.M.1    Dear, A.2    Craig, J.M.3    Norman, P.E.4    Golledge, J.5
  • 127
    • 84983111414 scopus 로고    scopus 로고
    • The potential role of DNA methylation in the pathogenesis of abdominal aortic aneurysm
    • B. J. Toghill, A. Saratzis, S. C. Harrison, A. R. Verissimo, E. B. Mallon, and M. J. Bown, "Te potential role of DNA methylation in the pathogenesis of abdominal aortic aneurysm," Atherosclerosis, vol. 241, no. 1, pp. 121-129, 2015.
    • (2015) Atherosclerosis , vol.241 , Issue.1 , pp. 121-129
    • Toghill, B.J.1    Saratzis, A.2    Harrison, S.C.3    Verissimo, A.R.4    Mallon, E.B.5    Bown, M.J.6
  • 128
    • 0035282903 scopus 로고    scopus 로고
    • Mice def-cient in methylenetetrahydrofolate reductase exhibit hyper-homocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
    • Z. Chen, A. C. Karaplis, S. L. Ackerman et al., "Mice def-cient in methylenetetrahydrofolate reductase exhibit hyper-homocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition," Human Molecular Genetics, vol. 10, no. 5, pp. 433-443, 2001.
    • (2001) Human Molecular Genetics , vol.10 , Issue.5 , pp. 433-443
    • Chen, Z.1    Karaplis, A.C.2    Ackerman, S.L.3
  • 129
    • 84883499033 scopus 로고    scopus 로고
    • Cigarette smoking and DNA methylation
    • article no. 132
    • K. W. K. Lee and Z. Pausova, "Cigarette smoking and DNA methylation," Frontiers in Genetics, vol. 4, article no. 132, 2013.
    • (2013) Frontiers in Genetics , vol.4
    • Lee, K.W.K.1    Pausova, Z.2
  • 130
    • 79953706343 scopus 로고    scopus 로고
    • Tobacco-smoking-related differential DNA methylation: 27K discovery and replication
    • L. P. Breitling, R. Yang, B. Korn, B. Burwinkel, and H. Brenner, "Tobacco-smoking-related differential DNA methylation: 27K discovery and replication," American Journal of Human Genetics, vol. 88, no. 4, pp. 450-457, 2011.
    • (2011) American Journal of Human Genetics , vol.88 , Issue.4 , pp. 450-457
    • Breitling, L.P.1    Yang, R.2    Korn, B.3    Burwinkel, B.4    Brenner, H.5
  • 132
    • 55849115277 scopus 로고    scopus 로고
    • Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons
    • R. Satta, E. Maloku, A. Zhubi et al., "Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons," Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 42, pp. 16356-16361, 2008.
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.42 , pp. 16356-16361
    • Satta, R.1    Maloku, E.2    Zhubi, A.3
  • 134
    • 84922021718 scopus 로고    scopus 로고
    • Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
    • L. G. Tsaprouni, T.-P. Yang, J. Bell et al., "Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation," Epigenetics, vol. 9, no. 10, pp. 1382-1396, 2014.
    • (2014) Epigenetics , vol.9 , Issue.10 , pp. 1382-1396
    • Tsaprouni, L.G.1    Yang, T.-P.2    Bell, J.3
  • 135
    • 84969931919 scopus 로고    scopus 로고
    • Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study
    • S. Ambatipudi, C. Cuenin, H. Hernandez-Vargas et al., "Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study," Epigenomics, vol. 8, no. 5, pp. 599-618, 2016.
    • (2016) Epigenomics , vol.8 , Issue.5 , pp. 599-618
    • Ambatipudi, S.1    Cuenin, C.2    Hernandez-Vargas, H.3
  • 137
    • 79958754527 scopus 로고    scopus 로고
    • Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
    • J. Sandoval, H. A. Heyn, S. Moran et al., "Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome," Epigenetics, vol. 6, no. 6, pp. 692-702, 2011.
    • (2011) Epigenetics , vol.6 , Issue.6 , pp. 692-702
    • Sandoval, J.1    Heyn, H.A.2    Moran, S.3
  • 138
    • 33845324531 scopus 로고    scopus 로고
    • DNA methy-lation paradigm shif: 15-lipoxygenase-1 upregulation in pro-static intraepithelial neoplasia and prostate cancer by atypical promoter hypermethylation
    • U. P. Kelavkar, N. S. Harya, J. Hutzley et al., "DNA methy-lation paradigm shif: 15-lipoxygenase-1 upregulation in pro-static intraepithelial neoplasia and prostate cancer by atypical promoter hypermethylation," Prostaglandins and Other Lipid Mediators, vol. 82, no. 1-4, pp. 185-197, 2007.
    • (2007) Prostaglandins and Other Lipid Mediators , vol.82 , Issue.1-4 , pp. 185-197
    • Kelavkar, U.P.1    Harya, N.S.2    Hutzley, J.3
  • 139
    • 17044400917 scopus 로고    scopus 로고
    • Smoking promotes pathogenesis of aortic aneurysm through the 5-lipoxygenase pathway
    • H. Takagi and T. Umemoto, "Smoking promotes pathogenesis of aortic aneurysm through the 5-lipoxygenase pathway," Medical Hypotheses, vol. 64, no. 6, pp. 1117-1119, 2005.
    • (2005) Medical Hypotheses , vol.64 , Issue.6 , pp. 1117-1119
    • Takagi, H.1    Umemoto, T.2
  • 141
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • V. L. Wilson and P. A. Jones, "DNA methylation decreases in aging but not in immortal cells," Science, vol. 220, no. 4601, pp. 1055-1057, 1983.
    • (1983) Science , vol.220 , Issue.4601 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 142
    • 84928728856 scopus 로고    scopus 로고
    • Aging and DNA methylation
    • article 7
    • M. Jung and G. P. Pfeifer, "Aging and DNA methylation," BMC Biology, vol. 13, article 7, 2015.
    • (2015) BMC Biology , vol.13
    • Jung, M.1    Pfeifer, G.P.2
  • 143
    • 0035989528 scopus 로고    scopus 로고
    • DNA hypomethylation and methyltransferase expression in atherosclerotic lesions
    • M. O. Hiltunen, M. P. Turunen, T. P. Häkkinen et al., "DNA hypomethylation and methyltransferase expression in atherosclerotic lesions," Vascular Medicine, vol. 7, no. 1, pp. 5-11, 2002.
    • (2002) Vascular Medicine , vol.7 , Issue.1 , pp. 5-11
    • Hiltunen, M.O.1    Turunen, M.P.2    Häkkinen, T.P.3
  • 144
    • 84957548931 scopus 로고    scopus 로고
    • Efect of MTHFR gene polymorphism impact on atherosclerosis via genome-wide methylation
    • X. Lin, W. Zhang, Q. Lu et al., "Efect of MTHFR gene polymorphism impact on atherosclerosis via genome-wide methylation," Medical Science Monitor, vol. 22, pp. 341-345, 2016.
    • (2016) Medical Science Monitor , vol.22 , pp. 341-345
    • Lin, X.1    Zhang, W.2    Lu, Q.3
  • 146
    • 33244486870 scopus 로고    scopus 로고
    • Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofo-late reductase gene in selected Egyptian subjects
    • M. El-Sammak, M. Kandil, S. El-Hifni, R. Hosni, and M. Ragab, "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofo-late reductase gene in selected Egyptian subjects," International Journal of Medical Sciences, vol. 1, no. 3, pp. 181-192, 2004.
    • (2004) International Journal of Medical Sciences , vol.1 , Issue.3 , pp. 181-192
    • El-Sammak, M.1    Kandil, M.2    El-Hifni, S.3    Hosni, R.4    Ragab, M.5
  • 147
    • 0142219380 scopus 로고    scopus 로고
    • Age Dependence of the Infuence of Methylenetetrahydrofolate Reductase Genotype on Plasma Homocysteine Level
    • L. D. Spotila, P. F. Jacques, P. B. Berger, K. V. Ballman, R. C. Ellison, and R. Rozen, "Age Dependence of the Infuence of Methylenetetrahydrofolate Reductase Genotype on Plasma Homocysteine Level," American Journal of Epidemiology, vol. 158, no. 9, pp. 871-877, 2003.
    • (2003) American Journal of Epidemiology , vol.158 , Issue.9 , pp. 871-877
    • Spotila, L.D.1    Jacques, P.F.2    Berger, P.B.3    Ballman, K.V.4    Ellison, R.C.5    Rozen, R.6
  • 148
    • 2942716893 scopus 로고    scopus 로고
    • Efect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and diferent lifestyle factors
    • A. Straßburg, C. Krems, P. M. Lührmann, B. Hartmann, and M. Neuhäuser-Berthold, "Efect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and diferent lifestyle factors," International Journal for Vitamin and Nutrition Research, vol. 74, no. 2, pp. 129-136, 2004.
    • (2004) International Journal for Vitamin and Nutrition Research , vol.74 , Issue.2 , pp. 129-136
    • Straßburg, A.1    Krems, C.2    Lührmann, P.M.3    Hartmann, B.4    Neuhäuser-Berthold, M.5
  • 149
    • 84886111619 scopus 로고    scopus 로고
    • DNA methylation age of human tissues and cell types
    • article R115
    • S. Horvath, "DNA methylation age of human tissues and cell types," Genome Biology, vol. 14, no. 10, article R115, 2013.
    • (2013) Genome Biology , vol.14 , Issue.10
    • Horvath, S.1
  • 151
    • 84863942908 scopus 로고    scopus 로고
    • Methylation status of CpG sites in the MCP-1 promoter is correlated to serum MCP-1 in type 2 diabetes
    • Z. H. Liu, L. L. Chen, X. L. Deng et al., "Methylation status of CpG sites in the MCP-1 promoter is correlated to serum MCP-1 in type 2 diabetes," Journal of Endocrinological Investigation, vol. 35, no. 6, pp. 585-589, 2012.
    • (2012) Journal of Endocrinological Investigation , vol.35 , Issue.6 , pp. 585-589
    • Liu, Z.H.1    Chen, L.L.2    Deng, X.L.3
  • 152
    • 34447513163 scopus 로고    scopus 로고
    • Epigenetic regulation of tumor necrosis factor alpha
    • K. E. Sullivan, A. B. M. Reddy, K. Dietzmann et al., "Epigenetic regulation of tumor necrosis factor alpha," Molecular and Cellular Biology, vol. 27, no. 14, pp. 5147-5160, 2007.
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.14 , pp. 5147-5160
    • Sullivan, K.E.1    Reddy, A.B.M.2    Dietzmann, K.3
  • 153
    • 84906925333 scopus 로고    scopus 로고
    • Hyperhomocysteinemia-induced monocyte chemoattractant protein-1 promoter DNA methylation by nuclear factor-αB/DNA methyltransferase 1 in apolipoprotein E-defcient mice
    • J. Wang, Y. Jiang, A. Yang et al., "Hyperhomocysteinemia-induced monocyte chemoattractant protein-1 promoter DNA methylation by nuclear factor-αB/DNA methyltransferase 1 in apolipoprotein E-defcient mice," BioResearch Open Access, vol. 2, no. 2, pp. 118-127, 2013.
    • (2013) BioResearch Open Access , vol.2 , Issue.2 , pp. 118-127
    • Wang, J.1    Jiang, Y.2    Yang, A.3
  • 154
    • 77953530683 scopus 로고    scopus 로고
    • Changes in chromatin structure and methylation of the human interleukin-1α gene during monopoiesis
    • I. Wessels, D. Fleischer, L. Rink, and P. Uciechowski, "Changes in chromatin structure and methylation of the human interleukin-1α gene during monopoiesis," Immunology, vol. 130, no. 3, pp. 410-417, 2010.
    • (2010) Immunology , vol.130 , Issue.3 , pp. 410-417
    • Wessels, I.1    Fleischer, D.2    Rink, L.3    Uciechowski, P.4
  • 155
    • 84966908186 scopus 로고    scopus 로고
    • Royal Jelly constituents increase the expression of extracellular superoxide dismutase through histone acetylation in monocytic THP-1 cells
    • J. Makino, R. Ogasawara, T. Kamiya et al., "Royal Jelly constituents increase the expression of extracellular superoxide dismutase through histone acetylation in monocytic THP-1 cells," Journal of Natural Products, vol. 79, no. 4, pp. 1137-1143, 2016.
    • (2016) Journal of Natural Products , vol.79 , Issue.4 , pp. 1137-1143
    • Makino, J.1    Ogasawara, R.2    Kamiya, T.3
  • 156
    • 84894580308 scopus 로고    scopus 로고
    • Acetylation of cyclophilin A is required for its secretion and vascular cell activation
    • N. N. Soe, M. Sowden, P. Baskaran et al., "Acetylation of cyclophilin A is required for its secretion and vascular cell activation," Cardiovascular Research, vol. 101, no. 3, pp. 444-453, 2014.
    • (2014) Cardiovascular Research , vol.101 , Issue.3 , pp. 444-453
    • Soe, N.N.1    Sowden, M.2    Baskaran, P.3
  • 157
    • 10044241543 scopus 로고    scopus 로고
    • Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-αB activation and proinfammatory cytokine release in alveolar epithelial cells
    • F. M. Moodie, J. A. Marwick, C. S. Anderson et al., "Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-αB activation and proinfammatory cytokine release in alveolar epithelial cells," The FASEB Journal, vol. 18, no. 15, pp. 1897-1899, 2004.
    • (2004) The FASEB Journal , vol.18 , Issue.15 , pp. 1897-1899
    • Moodie, F.M.1    Marwick, J.A.2    Anderson, C.S.3
  • 158
    • 59749094084 scopus 로고    scopus 로고
    • Epigenetic histone acetylation modifers in vascular remodelling: New targets for therapy in cardiovascular disease
    • D. Pons, F. R. de Vries, P. J. van den Elsen, B. T. Heijmans, P. H. A. Quax, and J. W. Jukema, "Epigenetic histone acetylation modifers in vascular remodelling: new targets for therapy in cardiovascular disease," European Heart Journal, vol. 30, no. 3, pp. 266-277, 2009.
    • (2009) European Heart Journal , vol.30 , Issue.3 , pp. 266-277
    • Pons, D.1    De Vries, F.R.2    Elsen Den Van, P.J.3    Heijmans, B.T.4    Quax, P.H.A.5    Jukema, J.W.6
  • 159
    • 84863738905 scopus 로고    scopus 로고
    • Novel pathways in the pathobiology of human abdominal aortic aneurysms
    • I. Hinterseher, R. Erdman, J. R. Elmore et al., "Novel pathways in the pathobiology of human abdominal aortic aneurysms," Pathobiology, vol. 80, no. 1, pp. 1-10, 2013.
    • (2013) Pathobiology , vol.80 , Issue.1 , pp. 1-10
    • Hinterseher, I.1    Erdman, R.2    Elmore, J.R.3
  • 160
    • 84862174374 scopus 로고    scopus 로고
    • MicroRNA expression signature in human abdominal aortic aneurysms
    • article 25
    • M. C. Pahl, K. Derr, G. Gäbel et al., "MicroRNA expression signature in human abdominal aortic aneurysms," BMC Medical Genomics, vol. 5, article 25, 2012.
    • (2012) BMC Medical Genomics , vol.5
    • Pahl, M.C.1    Derr, K.2    Gäbel, G.3
  • 161
    • 84880120745 scopus 로고    scopus 로고
    • Tissue- and plasma-specifc MicroRNA signatures for atherosclerotic abdominal aortic aneurysm
    • Article ID e000745
    • K. Kin, S. Miyagawa, S. Fukushima et al., "Tissue- and plasma-specifc MicroRNA signatures for atherosclerotic abdominal aortic aneurysm," Journal of the American Heart Association, vol. 1, no. 5, Article ID e000745, 2012.
    • (2012) Journal of the American Heart Association , vol.1 , Issue.5
    • Kin, K.1    Miyagawa, S.2    Fukushima, S.3
  • 162
    • 78650897480 scopus 로고    scopus 로고
    • MiR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation
    • S.-G. Sun, B. Zheng, M. Han et al., "MiR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation," EMBO Reports, vol. 12, no. 1, pp. 56-62, 2011.
    • (2011) EMBO Reports , vol.12 , Issue.1 , pp. 56-62
    • Sun, S.-G.1    Zheng, B.2    Han, M.3
  • 164
    • 84943553960 scopus 로고    scopus 로고
    • Plasma microRNAs serve as potential biomarkers for abdominal aortic aneurysm
    • W. Zhang, T. Shang, C. Huang et al., "Plasma microRNAs serve as potential biomarkers for abdominal aortic aneurysm," Clinical Biochemistry, vol. 48, no. 15, pp. 988-992, 2015.
    • (2015) Clinical Biochemistry , vol.48 , Issue.15 , pp. 988-992
    • Zhang, W.1    Shang, T.2    Huang, C.3
  • 165
    • 84929027152 scopus 로고    scopus 로고
    • Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease
    • P. W. Stather, N. Sylvius, D. A. Sidlof et al., "Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease," British Journal of Surgery, vol. 102, no. 7, pp. 755-766, 2015.
    • (2015) British Journal of Surgery , vol.102 , Issue.7 , pp. 755-766
    • Stather, P.W.1    Sylvius, N.2    Sidlof, D.A.3
  • 166
    • 80255137053 scopus 로고    scopus 로고
    • MicroRNA-29 in aortic dilation: Implications for aneurysm formation
    • R. A. Boon, T. Seeger, S. Heydt et al., "MicroRNA-29 in aortic dilation: implications for aneurysm formation," Circulation Research, vol. 109, no. 10, pp. 1115-1119, 2011.
    • (2011) Circulation Research , vol.109 , Issue.10 , pp. 1115-1119
    • Boon, R.A.1    Seeger, T.2    Heydt, S.3
  • 167
    • 84923380956 scopus 로고    scopus 로고
    • MiR-24 limits aortic vascular infammation and murine abdominal aneurysm development
    • L. Maegdefessel, J. M. Spin, U. Raaz et al., "miR-24 limits aortic vascular infammation and murine abdominal aneurysm development," Nature Communications, vol. 5, p. 5214, 2014.
    • (2014) Nature Communications , vol.5 , pp. 5214
    • Maegdefessel, L.1    Spin, J.M.2    Raaz, U.3
  • 168
    • 84903123297 scopus 로고    scopus 로고
    • Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice
    • C. W. Kim, S. Kumar, D. J. Son, I.-H. Jang, K. K. Griendling, and H. Jo, "Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice," Arteriosclerosis, Trombosis, and Vascular Biology, vol. 34, no. 7, pp. 1412-1421, 2014.
    • (2014) Arteriosclerosis, Trombosis, and Vascular Biology , vol.34 , Issue.7 , pp. 1412-1421
    • Kim, C.W.1    Kumar, S.2    Son, D.J.3    Jang, I.-H.4    Griendling, K.K.5    Jo, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.