-
1
-
-
84873872323
-
Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk
-
Staser, K., Park, S.J., Rhodes, S.D., Zeng, Y., He, Y.Z., Shew, M. A., Gehlhausen, J.R., Cerabona, D., Menon, K., Chen, S. et al. (2013) Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk. J. Clin. Invest., 123, 329-334.
-
(2013)
J. Clin. Invest
, vol.123
, pp. 329-334
-
-
Staser, K.1
Park, S.J.2
Rhodes, S.D.3
Zeng, Y.4
He, Y.Z.5
Shew, M.A.6
Gehlhausen, J.R.7
Cerabona, D.8
Menon, K.9
Chen, S.10
-
2
-
-
0012376721
-
Cardiovascular disease in neurofibromatosis 1: report of the NF1 cardiovascular task force
-
Friedman, J.M., Arbiser, J., Epstein, J.A., Gutmann, D.H., Huot, S.J., Lin, A.E., McManus, B. and Korf, B.R. (2002) Cardiovascular disease in neurofibromatosis 1: report of the NF1 cardiovascular task force. Genet. Med., 4, 105-111.
-
(2002)
Genet. Med
, vol.4
, pp. 105-111
-
-
Friedman, J.M.1
Arbiser, J.2
Epstein, J.A.3
Gutmann, D.H.4
Huot, S.J.5
Lin, A.E.6
McManus, B.7
Korf, B.R.8
-
3
-
-
34548511992
-
Vascular abnormalities in patients with neurofibromatosis syndrome type I: clinical spectrum, management, and results
-
Oderich, G.S., Sullivan, T.M., Bower, T.C., Gloviczki, P., Miller, D.V., Babovic-Vuksanovic, D., Macedo, T.A. and Stanson, A. (2007) Vascular abnormalities in patients with neurofibromatosis syndrome type I: clinical spectrum, management, and results. J. Vasc. Surg., 46, 475-484.
-
(2007)
J. Vasc. Surg
, vol.46
, pp. 475-484
-
-
Oderich, G.S.1
Sullivan, T.M.2
Bower, T.C.3
Gloviczki, P.4
Miller, D.V.5
Babovic-Vuksanovic, D.6
Macedo, T.A.7
Stanson, A.8
-
4
-
-
0035025409
-
Mortality in neurofibromatosis 1: an analysis using U.S. death certificates
-
Rasmussen, S.A., Yang, Q. and Friedman, J.M. (2001) Mortality in neurofibromatosis 1: an analysis using U.S. death certificates. Am. J. Hum. Genet., 68, 1110-1118.
-
(2001)
Am. J. Hum. Genet
, vol.68
, pp. 1110-1118
-
-
Rasmussen, S.A.1
Yang, Q.2
Friedman, J.M.3
-
5
-
-
0034645518
-
Cardiovascular malformations and other cardiovascular abnormalities in neurofibromatosis 1
-
Lin, A.E., Birch, P.H., Korf, B.R., Tenconi, R., Niimura, M., Poyhonen, M., Armfield Uhas, K., Sigorini, M., Virdis, R., Romano, C. et al. (2000) Cardiovascular malformations and other cardiovascular abnormalities in neurofibromatosis 1. Am. J. Med. Genet., 95, 108-117.
-
(2000)
Am. J. Med. Genet
, vol.95
, pp. 108-117
-
-
Lin, A.E.1
Birch, P.H.2
Korf, B.R.3
Tenconi, R.4
Niimura, M.5
Poyhonen, M.6
Armfield Uhas, K.7
Sigorini, M.8
Virdis, R.9
Romano, C.10
-
6
-
-
84902192072
-
Cerebrovascular stenosis in neurofibromatosis type 1 and utility of magnetic resonance angiography: our experience and literature review
-
D'Arco, F., D'Amico, A., Caranci, F., Di Paolo, N., Melis, D. and Brunetti, A. (2014) Cerebrovascular stenosis in neurofibromatosis type 1 and utility of magnetic resonance angiography: our experience and literature review. Radiol. Med., 119, 415-421.
-
(2014)
Radiol. Med
, vol.119
, pp. 415-421
-
-
D'Arco, F.1
D'Amico, A.2
Caranci, F.3
Di Paolo, N.4
Melis, D.5
Brunetti, A.6
-
7
-
-
70349257973
-
Cerebral arteriopathy in children with neurofibromatosis type 1
-
Rea, D., Brandsema, J.F., Armstrong, D., Parkin, P.C., deVeber, G., MacGregor, D., Logan, W.J. and Askalan, R. (2009) Cerebral arteriopathy in children with neurofibromatosis type 1. Pediatrics, 124, e476-e483.
-
(2009)
Pediatrics
, vol.124
, pp. e476-e483
-
-
Rea, D.1
Brandsema, J.F.2
Armstrong, D.3
Parkin, P.C.4
deVeber, G.5
MacGregor, D.6
Logan, W.J.7
Askalan, R.8
-
8
-
-
0016238151
-
The vascular lesions of neurofibromatosis
-
Salyer, W.R. and Salyer, D.C. (1974) The vascular lesions of neurofibromatosis. Angiology, 25, 510-519.
-
(1974)
Angiology
, vol.25
, pp. 510-519
-
-
Salyer, W.R.1
Salyer, D.C.2
-
9
-
-
33751098278
-
Sudden cardiac death in young children with neurofibromatosis type 1
-
Kanter, R.J., Graham, M., Fairbrother, D. and Smith, S.V. (2006) Sudden cardiac death in young children with neurofibromatosis type 1. J. Pediatr., 149, 718-720.
-
(2006)
J. Pediatr
, vol.149
, pp. 718-720
-
-
Kanter, R.J.1
Graham, M.2
Fairbrother, D.3
Smith, S.V.4
-
10
-
-
0033670127
-
Insights into the pathogenesis of neurofibromatosis 1 vasculopathy
-
Hamilton, S.J. and Friedman, J.M. (2000) Insights into the pathogenesis of neurofibromatosis 1 vasculopathy. Clin. Genet., 58, 341-344.
-
(2000)
Clin. Genet
, vol.58
, pp. 341-344
-
-
Hamilton, S.J.1
Friedman, J.M.2
-
11
-
-
0031948360
-
Vasculopathies of neurofibromatosis type 1 (von Recklinghausen Disease)
-
Lie, J.T. (1998) Vasculopathies of neurofibromatosis type 1 (von Recklinghausen Disease). Cardiovasc. Pathol., 7, 97-108.
-
(1998)
Cardiovasc. Pathol
, vol.7
, pp. 97-108
-
-
Lie, J.T.1
-
12
-
-
48049101346
-
+/-mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway
-
+/-mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway. Hum. Mol. Genet., 17, 2336-2344.
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 2336-2344
-
-
Lasater, E.A.1
Bessler, W.K.2
Mead, L.E.3
Horn, W.E.4
Clapp, D.W.5
Conway, S.J.6
Ingram, D.A.7
Li, F.8
-
13
-
-
77949660093
-
Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans
-
Lasater, E.A., Li, F., Bessler, W.K., Estes, M.L., Vemula, S., Hingtgen, C.M., Dinauer, M.C., Kapur, R., Conway, S.J. and Ingram, D.A. Jr. (2010) Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. J. Clin. Invest., 120, 859-870.
-
(2010)
J. Clin. Invest
, vol.120
, pp. 859-870
-
-
Lasater, E.A.1
Li, F.2
Bessler, W.K.3
Estes, M.L.4
Vemula, S.5
Hingtgen, C.M.6
Dinauer, M.C.7
Kapur, R.8
Conway, S.J.9
Ingram, D.A.10
-
14
-
-
33744768354
-
Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells
-
Li, F., Munchhof, A.M., White, H.A., Mead, L.E., Krier, T.R., Fenoglio, A., Chen, S., Wu, X., Cai, S., Yang, F.C. et al. (2006) Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells. Hum. Mol. Genet., 15, 1921-1930.
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 1921-1930
-
-
Li, F.1
Munchhof, A.M.2
White, H.A.3
Mead, L.E.4
Krier, T.R.5
Fenoglio, A.6
Chen, S.7
Wu, X.8
Cai, S.9
Yang, F.C.10
-
15
-
-
84873416941
-
Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatinsensitive cellular pathway
-
Stansfield, B.K., Bessler, W.K., Mali, R., Mund, J.A., Downing, B., Li, F., Sarchet, K.N., DiStasi, M.R., Conway, S.J., Kapur, R. et al. (2013) Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatinsensitive cellular pathway. Hum. Mol. Genet., 22, 977-988.
-
(2013)
Hum. Mol. Genet
, vol.22
, pp. 977-988
-
-
Stansfield, B.K.1
Bessler, W.K.2
Mali, R.3
Mund, J.A.4
Downing, B.5
Li, F.6
Sarchet, K.N.7
DiStasi, M.R.8
Conway, S.J.9
Kapur, R.10
-
16
-
-
84945435972
-
Clinical significance of monocyte heterogeneity
-
Stansfield, B.K. and Ingram, D.A. (2015) Clinical significance of monocyte heterogeneity. Clin. Transl. Med., 4, 5.
-
(2015)
Clin. Transl. Med
, vol.4
, pp. 5
-
-
Stansfield, B.K.1
Ingram, D.A.2
-
17
-
-
84901056045
-
Ly-6C high monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium
-
Hilgendorf, I., Gerhardt, L.M., Tan, T.C., Winter, C., Holderried, T.A., Chousterman, B.G., Iwamoto, Y., Liao, R., Zirlik, A., Scherer-Crosbie, M. et al. (2014) Ly-6C high monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ. Res., 114, 1611-1622.
-
(2014)
Circ. Res
, vol.114
, pp. 1611-1622
-
-
Hilgendorf, I.1
Gerhardt, L.M.2
Tan, T.C.3
Winter, C.4
Holderried, T.A.5
Chousterman, B.G.6
Iwamoto, Y.7
Liao, R.8
Zirlik, A.9
Scherer-Crosbie, M.10
-
18
-
-
84856083908
-
Extramedullary hematopoiesis generates Ly-6C (high) monocytes that infiltrate atherosclerotic lesions
-
Robbins, C.S., Chudnovskiy, A., Rauch, P.J., Figueiredo, J.L., Iwamoto, Y., Gorbatov, R., Etzrodt, M., Weber, G.F., Ueno, T., van Rooijen, N. et al. (2012) Extramedullary hematopoiesis generates Ly-6C (high) monocytes that infiltrate atherosclerotic lesions. Circulation, 125, 364-374.
-
(2012)
Circulation
, vol.125
, pp. 364-374
-
-
Robbins, C.S.1
Chudnovskiy, A.2
Rauch, P.J.3
Figueiredo, J.L.4
Iwamoto, Y.5
Gorbatov, R.6
Etzrodt, M.7
Weber, G.F.8
Ueno, T.9
van Rooijen, N.10
-
19
-
-
33644559719
-
The MCP-1/CCR2 system has direct proinflammatory effects in human mesangial cells
-
Giunti, S., Pinach, S., Arnaldi, L., Viberti, G., Perin, P.C., Camussi, G. and Gruden, G. (2006) The MCP-1/CCR2 system has direct proinflammatory effects in human mesangial cells. Kidney Int., 69, 856-863.
-
(2006)
Kidney Int
, vol.69
, pp. 856-863
-
-
Giunti, S.1
Pinach, S.2
Arnaldi, L.3
Viberti, G.4
Perin, P.C.5
Camussi, G.6
Gruden, G.7
-
20
-
-
72849142816
-
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice
-
Tieu, B.C., Lee, C., Sun, H., Lejeune, W., Recinos, A. 3rd, Ju, X., Spratt, H., Guo, D.C., Milewicz, D., Tilton, R.G. et al. (2009) An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. J. Clin. Invest., 119, 3637-3651.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 3637-3651
-
-
Tieu, B.C.1
Lee, C.2
Sun, H.3
Lejeune, W.4
Recinos, A.5
Ju, X.6
Spratt, H.7
Guo, D.C.8
Milewicz, D.9
Tilton, R.G.10
-
21
-
-
33646108358
-
MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes
-
Sakai, N., Wada, T., Furuichi, K., Shimizu, K., Kokubo, S., Hara, A., Yamahana, J., Okumura, T., Matsushima, K., Yokoyama, H. et al. (2006) MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes. J. Leukoc. Biol., 79, 555-563.
-
(2006)
J. Leukoc. Biol
, vol.79
, pp. 555-563
-
-
Sakai, N.1
Wada, T.2
Furuichi, K.3
Shimizu, K.4
Kokubo, S.5
Hara, A.6
Yamahana, J.7
Okumura, T.8
Matsushima, K.9
Yokoyama, H.10
-
22
-
-
84869756824
-
The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblasts
-
Lin, Y.M., Hsu, C.J., Liao, Y.Y., Chou, M.C. and Tang, C.H. (2012) The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblasts. PLoS ONE, 7, e49999.
-
(2012)
PLoS ONE
, vol.7
-
-
Lin, Y.M.1
Hsu, C.J.2
Liao, Y.Y.3
Chou, M.C.4
Tang, C.H.5
-
23
-
-
84856080961
-
A truncated analogue of CCL2 mediates anti-fibrotic effects on murine fibroblasts independently of CCR2
-
Kalderen, C., Forsgren, M., Karlstrom, U., Stefansson, K., Svensson, R., Berglund, M.M., Palm, G., Selander, M., Sundbom, M., Nilsson, J. et al. (2012) A truncated analogue of CCL2 mediates anti-fibrotic effects on murine fibroblasts independently of CCR2. Biochem. Pharmacol., 83, 644-652.
-
(2012)
Biochem. Pharmacol
, vol.83
, pp. 644-652
-
-
Kalderen, C.1
Forsgren, M.2
Karlstrom, U.3
Stefansson, K.4
Svensson, R.5
Berglund, M.M.6
Palm, G.7
Selander, M.8
Sundbom, M.9
Nilsson, J.10
-
24
-
-
77951155798
-
CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice
-
Si, Y., Tsou, C.L., Croft, K. and Charo, I.F. (2010) CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice. J. Clin. Invest., 120, 1192-1203.
-
(2010)
J. Clin. Invest
, vol.120
, pp. 1192-1203
-
-
Si, Y.1
Tsou, C.L.2
Croft, K.3
Charo, I.F.4
-
25
-
-
34147164049
-
Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrowand recruitment to inflammatory sites
-
Tsou, C.L., Peters, W., Si, Y., Slaymaker, S., Aslanian, A.M., Weisberg, S.P., Mack, M. and Charo, I.F. (2007) Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrowand recruitment to inflammatory sites. J. Clin. Invest., 117, 902-909.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 902-909
-
-
Tsou, C.L.1
Peters, W.2
Si, Y.3
Slaymaker, S.4
Aslanian, A.M.5
Weisberg, S.P.6
Mack, M.7
Charo, I.F.8
-
26
-
-
71849108112
-
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases
-
Hartl, D., Krauss-Etschmann, S., Koller, B., Hordijk, P.L., Kuijpers, T.W., Hoffmann, F., Hector, A., Eber, E., Marcos, V., Bittmann, I. et al. (2008) Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 181, 8053-8067.
-
(2008)
J. Immunol
, vol.181
, pp. 8053-8067
-
-
Hartl, D.1
Krauss-Etschmann, S.2
Koller, B.3
Hordijk, P.L.4
Kuijpers, T.W.5
Hoffmann, F.6
Hector, A.7
Eber, E.8
Marcos, V.9
Bittmann, I.10
-
27
-
-
84890414167
-
Ras-mek-erk signaling regulates nf1 heterozygous neointima formation
-
Stansfield, B.K., Bessler, W.K., Mali, R., Mund, J.A., Downing, B. D., Kapur, R. and Ingram, D.A. Jr. (2014) Ras-mek-erk signaling regulates nf1 heterozygous neointima formation. Am. J. Pathol., 184, 79-85.
-
(2014)
Am. J. Pathol
, vol.184
, pp. 79-85
-
-
Stansfield, B.K.1
Bessler, W.K.2
Mali, R.3
Mund, J.A.4
Downing, B.D.5
Kapur, R.6
Ingram, D.A.7
-
28
-
-
84867569419
-
Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching
-
Maddaluno, M., Grassia, G., Di Lauro, M.V., Parisi, A., Maione, F., Cicala, C., De Filippis, D., Iuvone, T., Guglielmotti, A., Maffia, P. et al. (2012) Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. PLoS ONE, 7, e47464.
-
(2012)
PLoS ONE
, vol.7
-
-
Maddaluno, M.1
Grassia, G.2
Di Lauro, M.V.3
Parisi, A.4
Maione, F.5
Cicala, C.6
De Filippis, D.7
Iuvone, T.8
Guglielmotti, A.9
Maffia, P.10
-
29
-
-
0031049110
-
Monocyte chemotactic protein 1 (MCP-1) is a mitogen for cultured rat vascular smooth muscle cells
-
Porreca, E., Di Febbo, C., Reale, M., Castellani, M.L., Baccante, G., Barbacane, R., Conti, P., Cuccurullo, F. and Poggi, A. (1997) Monocyte chemotactic protein 1 (MCP-1) is a mitogen for cultured rat vascular smooth muscle cells. J. Vasc. Res., 34, 58-65.
-
(1997)
J. Vasc. Res
, vol.34
, pp. 58-65
-
-
Porreca, E.1
Di Febbo, C.2
Reale, M.3
Castellani, M.L.4
Baccante, G.5
Barbacane, R.6
Conti, P.7
Cuccurullo, F.8
Poggi, A.9
-
30
-
-
0036784005
-
Monocyte chemotactic protein-1 directly induces human vascular smooth muscle proliferation
-
Selzman, C.H., Miller, S.A., Zimmerman, M.A., Gamboni-Robertson, F., Harken, A.H. and Banerjee, A. (2002) Monocyte chemotactic protein-1 directly induces human vascular smooth muscle proliferation. Am J Physiol. Heart Circ. Physiol., 283, H1455-H1461.
-
(2002)
Am J Physiol. Heart Circ. Physiol
, vol.283
, pp. H1455-H1461
-
-
Selzman, C.H.1
Miller, S.A.2
Zimmerman, M.A.3
Gamboni-Robertson, F.4
Harken, A.H.5
Banerjee, A.6
-
31
-
-
0036075148
-
Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1
-
Viedt, C., Vogel, J., Athanasiou, T., Shen, W., Orth, S.R., Kubler, W. and Kreuzer, J. (2002) Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1. Arterioscler. Thromb. Vasc. Biol., 22, 914-920.
-
(2002)
Arterioscler. Thromb. Vasc. Biol
, vol.22
, pp. 914-920
-
-
Viedt, C.1
Vogel, J.2
Athanasiou, T.3
Shen, W.4
Orth, S.R.5
Kubler, W.6
Kreuzer, J.7
-
32
-
-
33144460421
-
Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated by MCP-1 and RANTES
-
Kim, M.S., Magno, C.L., Day, C.J. and Morrison, N.A. (2006) Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated by MCP-1 and RANTES. J. Cell. Biochem., 97, 512-518.
-
(2006)
J. Cell. Biochem
, vol.97
, pp. 512-518
-
-
Kim, M.S.1
Magno, C.L.2
Day, C.J.3
Morrison, N.A.4
-
33
-
-
2642586618
-
MCP-1-dependent signaling in CCR2(-/-) aortic smooth muscle cells
-
Schecter, A.D., Berman, A.B., Yi, L., Ma, H., Daly, C.M., Soejima, K., Rollins, B.J., Charo, I.F. and Taubman, M.B. (2004) MCP-1-dependent signaling in CCR2(-/-) aortic smooth muscle cells. J. Leukoc. Biol., 75, 1079-1085.
-
(2004)
J. Leukoc. Biol
, vol.75
, pp. 1079-1085
-
-
Schecter, A.D.1
Berman, A.B.2
Yi, L.3
Ma, H.4
Daly, C.M.5
Soejima, K.6
Rollins, B.J.7
Charo, I.F.8
Taubman, M.B.9
-
34
-
-
79959248212
-
Discovery of INCB3284, a potent, selective, and orally bioavailable hCCR2 antagonist
-
Xue, C.B., Feng, H., Cao, G., Huang, T., Glenn, J., Anand, R., Meloni, D., Zhang, K., Kong, L., Wang, A. et al. (2011) Discovery of INCB3284, a potent, selective, and orally bioavailable hCCR2 antagonist. ACS Med. Chem. Lett., 2, 450-454.
-
(2011)
ACS Med. Chem. Lett
, vol.2
, pp. 450-454
-
-
Xue, C.B.1
Feng, H.2
Cao, G.3
Huang, T.4
Glenn, J.5
Anand, R.6
Meloni, D.7
Zhang, K.8
Kong, L.9
Wang, A.10
-
35
-
-
84882570935
-
Monocyte heterogeneity in cardiovascular disease
-
Libby, P., Nahrendorf, M. and Swirski, F.K. (2013) Monocyte heterogeneity in cardiovascular disease. Semin. Immunopathol., 35, 553-562.
-
(2013)
Semin. Immunopathol
, vol.35
, pp. 553-562
-
-
Libby, P.1
Nahrendorf, M.2
Swirski, F.K.3
-
36
-
-
33645902493
-
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
-
Serbina, N.V. and Pamer, E.G. (2006) Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol., 7, 311-317.
-
(2006)
Nat. Immunol
, vol.7
, pp. 311-317
-
-
Serbina, N.V.1
Pamer, E.G.2
-
37
-
-
21344441247
-
Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice
-
Ishibashi, M., Egashira, K., Zhao, Q., Hiasa, K., Ohtani, K., Ihara, Y., Charo, I.F., Kura, S., Tsuzuki, T., Takeshita, A. et al. (2004) Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice. Arterioscler. Thromb. Vasc. Biol., 24, e174-e178.
-
(2004)
Arterioscler. Thromb. Vasc. Biol
, vol.24
, pp. e174-e178
-
-
Ishibashi, M.1
Egashira, K.2
Zhao, Q.3
Hiasa, K.4
Ohtani, K.5
Ihara, Y.6
Charo, I.F.7
Kura, S.8
Tsuzuki, T.9
Takeshita, A.10
-
38
-
-
78449282952
-
A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice
-
Liehn, E.A., Piccinini, A.M., Koenen, R.R., Soehnlein, O., Adage, T., Fatu, R., Curaj, A., Popescu, A., Zernecke, A., Kungl, A.J. et al. (2010) A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice. J. Am. College Cardiol., 56, 1847-1857.
-
(2010)
J. Am. College Cardiol
, vol.56
, pp. 1847-1857
-
-
Liehn, E.A.1
Piccinini, A.M.2
Koenen, R.R.3
Soehnlein, O.4
Adage, T.5
Fatu, R.6
Curaj, A.7
Popescu, A.8
Zernecke, A.9
Kungl, A.J.10
-
39
-
-
9344245693
-
Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets
-
Schober, A., Zernecke, A., Liehn, E.A., von Hundelshausen, P., Knarren, S., Kuziel, W.A. and Weber, C. (2004) Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets. Circ. Res., 95, 1125-1133.
-
(2004)
Circ. Res
, vol.95
, pp. 1125-1133
-
-
Schober, A.1
Zernecke, A.2
Liehn, E.A.3
von Hundelshausen, P.4
Knarren, S.5
Kuziel, W.A.6
Weber, C.7
-
40
-
-
0036075323
-
Distinction in genetic determinants for injury-induced neointimal hyperplasia and diet-induced atherosclerosis in inbred mice
-
Kuhel, D.G., Zhu, B., Witte, D.P. and Hui, D.Y. (2002) Distinction in genetic determinants for injury-induced neointimal hyperplasia and diet-induced atherosclerosis in inbred mice. Arterioscler. Thromb. Vasc. Biol., 22, 955-960.
-
(2002)
Arterioscler. Thromb. Vasc. Biol
, vol.22
, pp. 955-960
-
-
Kuhel, D.G.1
Zhu, B.2
Witte, D.P.3
Hui, D.Y.4
-
41
-
-
0031010175
-
Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors
-
Gong, X., Gong, W., Kuhns, D.B., Ben-Baruch, A., Howard, O.M. andWang, J.M. (1997) Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors. J. Biol. Chem., 272, 11682-11685.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 11682-11685
-
-
Gong, X.1
Gong, W.2
Kuhns, D.B.3
Ben-Baruch, A.4
Howard O.M.andWang, J.M.5
-
42
-
-
79960239411
-
Monocyte chemotactic protein-3 induces human coronary smooth muscle cell proliferation
-
Maddaluno, M., Di Lauro, M., Di Pascale, A., Santamaria, R., Guglielmotti, A., Grassia, G. and Ialenti, A. (2011) Monocyte chemotactic protein-3 induces human coronary smooth muscle cell proliferation. Atherosclerosis, 217, 113-119.
-
(2011)
Atherosclerosis
, vol.217
, pp. 113-119
-
-
Maddaluno, M.1
Di Lauro, M.2
Di Pascale, A.3
Santamaria, R.4
Guglielmotti, A.5
Grassia, G.6
Ialenti, A.7
-
43
-
-
84872567380
-
Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein-1 (MCP-1)/chemokine (C-C motif ) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells
-
Li, X. and Tai, H.H. (2013) Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein-1 (MCP-1)/chemokine (C-C motif ) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells. PLoS ONE, 8, e54073.
-
(2013)
PLoS ONE
, vol.8
-
-
Li, X.1
Tai, H.H.2
-
44
-
-
70350704801
-
Interleukin-1beta promotes the expression of monocyte chemoattractant protein-1 in human aorta smooth muscle cells via multiple signaling pathways
-
Lim, J.H., Um, H.J., Park, J.W., Lee, I.K. and Kwon, T.K. (2009) Interleukin-1beta promotes the expression of monocyte chemoattractant protein-1 in human aorta smooth muscle cells via multiple signaling pathways. Exp. Mol. Med., 41, 757-764.
-
(2009)
Exp. Mol. Med
, vol.41
, pp. 757-764
-
-
Lim, J.H.1
Um, H.J.2
Park, J.W.3
Lee, I.K.4
Kwon, T.K.5
-
45
-
-
84859111301
-
Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-kappaB, p53, ERK, and JNK in proximal tubular cells
-
Shimizu, H., Bolati, D., Higashiyama, Y., Nishijima, F., Shimizu, K. and Niwa, T. (2012) Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-kappaB, p53, ERK, and JNK in proximal tubular cells. Life Sci., 90, 525-530.
-
(2012)
Life Sci
, vol.90
, pp. 525-530
-
-
Shimizu, H.1
Bolati, D.2
Higashiyama, Y.3
Nishijima, F.4
Shimizu, K.5
Niwa, T.6
-
46
-
-
84860759450
-
Involvement of reactive oxygen species and JNK in increased expression of MCP-1 and infiltration of inflammatory cells in pressure-overloaded rat hearts
-
Shang, F., Wang, J., Liu, X., Li, J., Zheng, Q., Xue, Y. and Zhao, L. (2012) Involvement of reactive oxygen species and JNK in increased expression of MCP-1 and infiltration of inflammatory cells in pressure-overloaded rat hearts. Mol. Med. Rep., 5, 1491-1496.
-
(2012)
Mol. Med. Rep
, vol.5
, pp. 1491-1496
-
-
Shang, F.1
Wang, J.2
Liu, X.3
Li, J.4
Zheng, Q.5
Xue, Y.6
Zhao, L.7
-
47
-
-
0041854289
-
Signaling pathways for monocyte chemoattractant protein 1-mediated extracellular signal-regulated kinase activation
-
Jimenez-Sainz, M.C., Fast, B., Mayor, F. Jr and Aragay, A.M. (2003) Signaling pathways for monocyte chemoattractant protein 1-mediated extracellular signal-regulated kinase activation. Mol. Pharmacol., 64, 773-782.
-
(2003)
Mol. Pharmacol
, vol.64
, pp. 773-782
-
-
Jimenez-Sainz, M.C.1
Fast, B.2
Mayor, F.3
Aragay, A.M.4
-
48
-
-
78650656888
-
Myeloid-specific GPCR kinase-2 negatively regulates NF-kappaB1p105-ERK pathway and limits endotoxemic shock in mice
-
Patial, S., Saini, Y., Parvataneni, S., Appledorn, D.M., Dorn, G. W. 2nd, Lapres, J.J., Amalfitano, A., Senagore, P. and Parameswaran, N. (2011) Myeloid-specific GPCR kinase-2 negatively regulates NF-kappaB1p105-ERK pathway and limits endotoxemic shock in mice. J. Cell. Physiol., 226, 627-637.
-
(2011)
J. Cell. Physiol
, vol.226
, pp. 627-637
-
-
Patial, S.1
Saini, Y.2
Parvataneni, S.3
Appledorn, D.M.4
Dorn, G.W.5
Lapres, J.J.6
Amalfitano, A.7
Senagore, P.8
Parameswaran, N.9
-
49
-
-
84904274137
-
MCP-1 stimulates MMP-9 expression via ERK 1/2 and p38 MAPK signaling pathways in human aortic smooth muscle cells
-
Yang, C.Q., Li, W., Li, S.Q., Li, J., Li, Y.W., Kong, S.X., Liu, R.M., Wang, S.M. and Lv, W.M. (2014) MCP-1 stimulates MMP-9 expression via ERK 1/2 and p38 MAPK signaling pathways in human aortic smooth muscle cells. Cell. Physiol. Biochem., 34, 266-276.
-
(2014)
Cell. Physiol. Biochem
, vol.34
, pp. 266-276
-
-
Yang, C.Q.1
Li, W.2
Li, S.Q.3
Li, J.4
Li, Y.W.5
Kong, S.X.6
Liu, R.M.7
Wang, S.M.8
Lv, W.M.9
-
50
-
-
80955158815
-
Synthetic peptide fragment (65-76) of monocyte chemotactic protein-1 (MCP-1) inhibits MCP-1 binding to heparin and possesses anti-inflammatory activity in stable angina patients after coronary stenting
-
Arefieva, T.I., Krasnikova, T.L., Potekhina, A.V., Ruleva, N.U., Nikitin, P.I., Ksenevich, T.I., Gorshkov, B.G., Sidorova, M.V., Bespalova Zh, D., Kukhtina, N.B. et al. (2011) Synthetic peptide fragment (65-76) of monocyte chemotactic protein-1 (MCP-1) inhibits MCP-1 binding to heparin and possesses anti-inflammatory activity in stable angina patients after coronary stenting. Inflamm. Res., 60, 955-964.
-
(2011)
Inflamm. Res
, vol.60
, pp. 955-964
-
-
Arefieva, T.I.1
Krasnikova, T.L.2
Potekhina, A.V.3
Ruleva, N.U.4
Nikitin, P.I.5
Ksenevich, T.I.6
Gorshkov, B.G.7
Sidorova, M.V.8
Bespalova Zh, D.9
Kukhtina, N.B.10
-
51
-
-
36349000577
-
Local delivery of anti-monocyte chemoattractant protein-1 by gene-eluting stents attenuates in-stent stenosis in rabbits and monkeys
-
Egashira, K., Nakano, K., Ohtani, K., Funakoshi, K., Zhao, G., Ihara, Y., Koga, J., Kimura, S., Tominaga, R. and Sunagawa, K. (2007) Local delivery of anti-monocyte chemoattractant protein-1 by gene-eluting stents attenuates in-stent stenosis in rabbits and monkeys. Arterioscler. Thromb. Vasc. Biol., 27, 2563-2568.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 2563-2568
-
-
Egashira, K.1
Nakano, K.2
Ohtani, K.3
Funakoshi, K.4
Zhao, G.5
Ihara, Y.6
Koga, J.7
Kimura, S.8
Tominaga, R.9
Sunagawa, K.10
-
52
-
-
34848874132
-
Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgusmonkeys
-
Nakano, K., Egashira, K., Ohtani, K., Zhao, G., Funakoshi, K., Ihara, Y. and Sunagawa, K. (2007) Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgusmonkeys. Atherosclerosis, 194, 309-316.
-
(2007)
Atherosclerosis
, vol.194
, pp. 309-316
-
-
Nakano, K.1
Egashira, K.2
Ohtani, K.3
Zhao, G.4
Funakoshi, K.5
Ihara, Y.6
Sunagawa, K.7
-
53
-
-
4444295588
-
Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys
-
Ohtani, K., Usui, M., Nakano, K., Kohjimoto, Y., Kitajima, S., Hirouchi, Y., Li, X.H., Kitamoto, S., Takeshita, A. and Egashira, K. (2004) Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys. Gene Ther., 11, 1273-1282.
-
(2004)
Gene Ther
, vol.11
, pp. 1273-1282
-
-
Ohtani, K.1
Usui, M.2
Nakano, K.3
Kohjimoto, Y.4
Kitajima, S.5
Hirouchi, Y.6
Li, X.H.7
Kitamoto, S.8
Takeshita, A.9
Egashira, K.10
-
54
-
-
77954676361
-
Dual targeting of CCR2 and CCR5: therapeutic potential for immunologic and cardiovascular diseases
-
Zhao, Q. (2010) Dual targeting of CCR2 and CCR5: therapeutic potential for immunologic and cardiovascular diseases. J. Leukoc. Biol., 88, 41-55.
-
(2010)
J. Leukoc. Biol
, vol.88
, pp. 41-55
-
-
Zhao, Q.1
-
55
-
-
80054936616
-
Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries
-
Ialenti, A., Grassia, G., Gordon, P., Maddaluno, M., Di Lauro, M. V., Baker, A.H., Guglielmotti, A., Colombo, A., Biondi, G., Kennedy, S. et al. (2011) Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries. Arterioscler. Thromb. Vasc. Biol., 31, 2448-2454.
-
(2011)
Arterioscler. Thromb. Vasc. Biol
, vol.31
, pp. 2448-2454
-
-
Ialenti, A.1
Grassia, G.2
Gordon, P.3
Maddaluno, M.4
Di Lauro, M.V.5
Baker, A.H.6
Guglielmotti, A.7
Colombo, A.8
Biondi, G.9
Kennedy, S.10
-
56
-
-
70849097192
-
The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice
-
Grassia, G., Maddaluno, M., Guglielmotti, A., Mangano, G., Biondi, G., Maffia, P. and Ialenti, A. (2009) The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice. Cardiovasc. Res., 84, 485-493.
-
(2009)
Cardiovasc. Res
, vol.84
, pp. 485-493
-
-
Grassia, G.1
Maddaluno, M.2
Guglielmotti, A.3
Mangano, G.4
Biondi, G.5
Maffia, P.6
Ialenti, A.7
-
57
-
-
33746938320
-
A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis
-
Haringman, J.J., Gerlag, D.M., Smeets, T.J., Baeten, D., Van Den Bosch, F., Bresnihan, B., Breedveld, F.C., Dinant, H.J., Legay, F., Gram, H. et al. (2006) A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis. Arthritis Rheum., 54, 2387-2392.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2387-2392
-
-
Haringman, J.J.1
Gerlag, D.M.2
Smeets, T.J.3
Baeten, D.4
Van Den Bosch, F.5
Bresnihan, B.6
Breedveld, F.C.7
Dinant, H.J.8
Legay, F.9
Gram, H.10
-
58
-
-
45549097817
-
Insulin regulation ofMCP-1 inhuman adipose tissue of obese and lean women
-
Westerbacka, J., Corner, A., Kolak, M., Makkonen, J., Turpeinen, U., Hamsten, A., Fisher, R.M. and Yki-Jarvinen, H. (2008) Insulin regulation ofMCP-1 inhuman adipose tissue of obese and lean women. Am. J. Physiol. Endocrinol. Metab., 294, E841-E845.
-
(2008)
Am. J. Physiol. Endocrinol. Metab
, vol.294
, pp. E841-E845
-
-
Westerbacka, J.1
Corner, A.2
Kolak, M.3
Makkonen, J.4
Turpeinen, U.5
Hamsten, A.6
Fisher, R.M.7
Yki-Jarvinen, H.8
-
59
-
-
84862726271
-
MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy
-
Younce, C. and Kolattukudy, P. (2012) MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy. Cell. Physiol. Biochem., 30, 307-320.
-
(2012)
Cell. Physiol. Biochem
, vol.30
, pp. 307-320
-
-
Younce, C.1
Kolattukudy, P.2
-
60
-
-
79251534355
-
CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection
-
Lin, K.L., Sweeney, S., Kang, B.D., Ramsburg, E. and Gunn, M. D. (2011) CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection. J. Immunol., 186, 508-515.
-
(2011)
J. Immunol
, vol.186
, pp. 508-515
-
-
Lin, K.L.1
Sweeney, S.2
Kang, B.D.3
Ramsburg, E.4
Gunn, M.D.5
-
61
-
-
71549167047
-
CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
-
Mildner, A., Mack, M., Schmidt, H., Bruck, W., Djukic, M., Zabel, M.D., Hille, A., Priller, J. and Prinz, M. (2009) CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain, 132, 2487-2500.
-
(2009)
Brain
, vol.132
, pp. 2487-2500
-
-
Mildner, A.1
Mack, M.2
Schmidt, H.3
Bruck, W.4
Djukic, M.5
Zabel, M.D.6
Hille, A.7
Priller, J.8
Prinz, M.9
-
62
-
-
84886415833
-
Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes
-
Sullivan, T.J., Miao, Z., Zhao, B.N., Ertl, L.S., Wang, Y., Krasinski, A., Walters, M.J., Powers, J.P., Dairaghi, D.J., Baumgart, T. et al. (2013) Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes. Metabolism: Clin. Exp., 62, 1623-1632.
-
(2013)
Metabolism: Clin. Exp
, vol.62
, pp. 1623-1632
-
-
Sullivan, T.J.1
Miao, Z.2
Zhao, B.N.3
Ertl, L.S.4
Wang, Y.5
Krasinski, A.6
Walters, M.J.7
Powers, J.P.8
Dairaghi, D.J.9
Baumgart, T.10
-
63
-
-
84897541015
-
Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110alpha
-
Gritsman, K., Yuzugullu, H., Von, T., Yan, H., Clayton, L., Fritsch, C., Maira, S.M., Hollingworth, G., Choi, C., Khandan, T. et al. (2014) Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110alpha. J. Clin. Invest., 124, 1794-1809.
-
(2014)
J. Clin. Invest
, vol.124
, pp. 1794-1809
-
-
Gritsman, K.1
Yuzugullu, H.2
Von, T.3
Yan, H.4
Clayton, L.5
Fritsch, C.6
Maira, S.M.7
Hollingworth, G.8
Choi, C.9
Khandan, T.10
-
64
-
-
84928551116
-
Pak2 regulates hematopoietic progenitor cell proliferation, survival and differentiation
-
Zeng, Y., Broxmeyer, H.E., Staser, K., Chitteti, B.R., Park, S.J., Hahn, S., Cooper, S., Sun, Z., Jiang, L., Yang, X. et al. (2015) Pak2 regulates hematopoietic progenitor cell proliferation, survival and differentiation. Stem Cells, 33, 1630-1641.
-
(2015)
Stem Cells
, vol.33
, pp. 1630-1641
-
-
Zeng, Y.1
Broxmeyer, H.E.2
Staser, K.3
Chitteti, B.R.4
Park, S.J.5
Hahn, S.6
Cooper, S.7
Sun, Z.8
Jiang, L.9
Yang, X.10
-
65
-
-
9044251606
-
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
-
Bollag, G., Clapp, D.W., Shih, S., Adler, F., Zhang, Y.Y., Thompson, P., Lange, B.J., Freedman, M.H., McCormick, F., Jacks, T. et al. (1996) Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat. Genet., 12, 144-148.
-
(1996)
Nat. Genet
, vol.12
, pp. 144-148
-
-
Bollag, G.1
Clapp, D.W.2
Shih, S.3
Adler, F.4
Zhang, Y.Y.5
Thompson, P.6
Lange, B.J.7
Freedman, M.H.8
McCormick, F.9
Jacks, T.10
|