Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm

Biochemical and Biophysical Research Communications

Volumn 454, Issue 1, 2014, Pages 137-143

  Gao, Fu ^a   Chambon, Pierre ^b   Offermanns, Stefan ^c   Tellides, George ^d   Kong, Wei ^e   Zhang, Xiaoming ^a   Li, Wei ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b INSTITUT CLINIQUE DE LA SOURIS   (France)

^c MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e PEKING UNIVERSITY   (China)

Author keywords

Aneurysm; Elastase; Smooth muscle cell; TGF

Indexed keywords

ELASTASE; ELASTIN; GELATINASE B; MATRIX METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA; MMP9 PROTEIN, MOUSE; PANCREATIC ELASTASE; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ABDOMINAL AORTA ANEURYSM; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE DELETION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTIC ANEURYSM, ABDOMINAL; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; GENETICS; HETEROZYGOTE; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; UPREGULATION;

ANIMALS; AORTIC ANEURYSM, ABDOMINAL; DISEASE MODELS, ANIMAL; HETEROZYGOTE; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCYTES, SMOOTH MUSCLE; PANCREATIC ELASTASE; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84910667380     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.053     Document Type: Article

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