A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice

Journal of Vascular Research

Volumn 45, Issue 2, 2008, Pages 143-152

  Vinh, Antony ^a   Gaspari, Tracey A ^a   Liu, Hong Bin ^a   Dousha, Lovisha F ^a   Widdop, Robert E ^a   Dear, Anthony E ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Aneurysm; Histone deacetylase inhibitor; Matrix metalloproteinases; Metacept 1

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; DOXYCYCLINE; GELATINASE A; GELATINASE B; HISTONE DEACETYLASE INHIBITOR; METACEPT 1; ENZYME INHIBITOR; HISTONE DEACETYLASE; HYDROXAMIC ACID; METACEPT-1; MMP2 PROTEIN, HUMAN; MMP2 PROTEIN, RAT; MMP9 PROTEIN, MOUSE; PROTEINASE INHIBITOR; SULFONAMIDE; UNCLASSIFIED DRUG;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; WESTERN BLOTTING; ZYMOGRAPHY; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXYCYCLINE; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; PROTEASE INHIBITORS; RATS; SULFONAMIDES;

EID: 40749083602     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000110041     Document Type: Article

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