-
1
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. 2002. Nonalcoholic fatty liver disease. N. Engl. J. Med. 346:1221-31
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
2
-
-
84874645372
-
Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents 1988-1994 to 2007-2010
-
Welsh JA, Karpen S, Vos MB. 2013. Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988-1994 to 2007-2010. J. Pediatrics 162:496-500e1
-
(2013)
J. Pediatrics
, vol.162
, pp. 496-500e1
-
-
Welsh, J.A.1
Karpen, S.2
Vos, M.B.3
-
3
-
-
0344393668
-
Increase in the prevalence of fatty liver in Japan over the past 12 years: Analysis of clinical background
-
Kojima S, Watanabe N, Numata M, et al. 2003. Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical background. J. Gastroenterol. 38:954-61
-
(2003)
J. Gastroenterol.
, vol.38
, pp. 954-961
-
-
Kojima, S.1
Watanabe, N.2
Numata, M.3
-
4
-
-
12144259379
-
Magnetic resonance spectroscopy to measure hepatic triglyceride content: Prevalence of hepatic steatosis in the general population
-
Szczepaniak LS, Nurenberg P, Leonard D, et al. 2005. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am. J. Physiol. Endocrinol. Metab. 288:E462-68
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
, pp. E462-E468
-
-
Szczepaniak, L.S.1
Nurenberg, P.2
Leonard, D.3
-
5
-
-
78650486196
-
Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: A prospective study
-
Williams CD, Stengel J, Asike MI, et al. 2011. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology 140:124-31
-
(2011)
Gastroenterology
, vol.140
, pp. 124-131
-
-
Williams, C.D.1
Stengel, J.2
Asike, M.I.3
-
6
-
-
14644392822
-
Histological progression of non-alcoholic fatty liver disease in Chinese patients
-
Hui AY, Wong VW, Chan HL, et al. 2005. Histological progression of non-alcoholic fatty liver disease in Chinese patients. Aliment. Pharmacol. Ther. 21:407-13
-
(2005)
Aliment. Pharmacol. Ther.
, vol.21
, pp. 407-413
-
-
Hui, A.Y.1
Wong, V.W.2
Chan, H.L.3
-
7
-
-
0141510580
-
The natural history of nonalcoholic fatty liver disease: A clinical histopathological study
-
Harrison SA, Torgerson S, Hayashi PH. 2003. The natural history of nonalcoholic fatty liver disease: a clinical histopathological study. Am. J. Gastroenterol. 98:2042-47
-
(2003)
Am. J. Gastroenterol.
, vol.98
, pp. 2042-2047
-
-
Harrison, S.A.1
Torgerson, S.2
Hayashi, P.H.3
-
8
-
-
84938057875
-
Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease
-
Angulo P, Kleiner DE, Dam-Larsen S, et al. 2015. Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology 149:389-97e10
-
(2015)
Gastroenterology
, vol.149
, pp. 389-397e10
-
-
Angulo, P.1
Kleiner, D.E.2
Dam-Larsen, S.3
-
9
-
-
58849134985
-
Long-term follow-up of patients with nonalcoholic fatty liver
-
Rafiq N, Bai C, Fang Y, et al. 2009. Long-term follow-up of patients with nonalcoholic fatty liver. Clin. Gastroenterol. Hepatol. 7:234-38
-
(2009)
Clin. Gastroenterol. Hepatol.
, vol.7
, pp. 234-238
-
-
Rafiq, N.1
Bai, C.2
Fang, Y.3
-
10
-
-
79960029926
-
Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
-
Vernon G, Baranova A, Younossi ZM. 2011. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment. Pharmacol. Ther. 34:274-85
-
(2011)
Aliment. Pharmacol. Ther.
, vol.34
, pp. 274-285
-
-
Vernon, G.1
Baranova, A.2
Younossi, Z.M.3
-
11
-
-
44949183849
-
Association between low thigh fat and non-alcoholic fatty liver disease
-
Jun DW, Han JH, Kim SH, et al. 2008. Association between low thigh fat and non-alcoholic fatty liver disease. J. Gastroenterol. Hepatol. 23:888-93
-
(2008)
J. Gastroenterol. Hepatol.
, vol.23
, pp. 888-893
-
-
Jun, D.W.1
Han, J.H.2
Kim, S.H.3
-
12
-
-
35348815566
-
Body fat distribution and insulin resistance: Beyond obesity in nonalcoholic fatty liver disease among overweight men
-
Park SH, Kim BI, Kim SH, et al. 2007. Body fat distribution and insulin resistance: beyond obesity in nonalcoholic fatty liver disease among overweight men. J. Am. Coll. Nutr. 26:321-26
-
(2007)
J. Am. Coll. Nutr.
, vol.26
, pp. 321-326
-
-
Park, S.H.1
Kim, B.I.2
Kim, S.H.3
-
13
-
-
34447100647
-
Progressive fibrosis in nonalcoholic steatohepatitis: Association with altered regeneration and a ductular reaction
-
Richardson MM, Jonsson JR, Powell EE, et al. 2007. Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. Gastroenterology 133:80-90
-
(2007)
Gastroenterology
, vol.133
, pp. 80-90
-
-
Richardson, M.M.1
Jonsson, J.R.2
Powell, E.E.3
-
14
-
-
84971290761
-
Nonalcoholic fatty liver disease: Pathogenesis and disease spectrum
-
Hardy T, Oakley F, Anstee QM, et al. 2016. Nonalcoholic fatty liver disease: pathogenesis and disease spectrum. Annu. Rev. Pathol. 11:451-96
-
(2016)
Annu. Rev. Pathol.
, vol.11
, pp. 451-496
-
-
Hardy, T.1
Oakley, F.2
Anstee, Q.M.3
-
15
-
-
67650166809
-
Nonalcoholic fatty liver disease in women
-
Suzuki A, Abdelmalek MF. 2009. Nonalcoholic fatty liver disease in women. Womens Health 5:191-203
-
(2009)
Womens Health
, vol.5
, pp. 191-203
-
-
Suzuki, A.1
Abdelmalek, M.F.2
-
16
-
-
11244308124
-
Chronological development of elevated aminotransferases in a nonalcoholic population
-
Suzuki A, Angulo P, Lymp J, et al. 2005. Chronological development of elevated aminotransferases in a nonalcoholic population. Hepatology 41:64-71
-
(2005)
Hepatology
, vol.41
, pp. 64-71
-
-
Suzuki, A.1
Angulo, P.2
Lymp, J.3
-
17
-
-
0023714299
-
Prevalence of fatty liver in a general population of Okinawa, Japan
-
Nomura H, Kashiwagi S, Hayashi J, et al. 1988. Prevalence of fatty liver in a general population of Okinawa, Japan. Jpn. J. Med. 27:142-49
-
(1988)
Jpn. J. Med.
, vol.27
, pp. 142-149
-
-
Nomura, H.1
Kashiwagi, S.2
Hayashi, J.3
-
19
-
-
11144280457
-
Non-alcoholic fatty liver disease-A common and benign finding in octogenarian patients
-
Kagansky N, Levy S, Keter D, et al. 2004. Non-alcoholic fatty liver disease-a common and benign finding in octogenarian patients. Liver Int. 24:588-94
-
(2004)
Liver Int.
, vol.24
, pp. 588-594
-
-
Kagansky, N.1
Levy, S.2
Keter, D.3
-
20
-
-
20444449750
-
Should nonalcoholic fatty liver disease be treated differently in elderly patients
-
Suzuki A, Diehl AM. 2005. Should nonalcoholic fatty liver disease be treated differently in elderly patients Nat. Clin. Pract. Gastroenterol. Hepatol. 2:208-9
-
(2005)
Nat. Clin. Pract. Gastroenterol. Hepatol.
, vol.2
, pp. 208-209
-
-
Suzuki, A.1
Diehl, A.M.2
-
21
-
-
40949141827
-
Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease
-
Chalasani N, Wilson L, Kleiner DE, et al. 2008. Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease. J. Hepatol. 48:829-34
-
(2008)
J. Hepatol.
, vol.48
, pp. 829-834
-
-
Chalasani, N.1
Wilson, L.2
Kleiner, D.E.3
-
22
-
-
34250356015
-
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
-
Yamaguchi K, Yang L, McCall S, et al. 2007. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology 45:1366-74
-
(2007)
Hepatology
, vol.45
, pp. 1366-1374
-
-
Yamaguchi, K.1
Yang, L.2
McCall, S.3
-
23
-
-
84904015435
-
Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells
-
Leamy AK, Egnatchik RA, Shiota M, et al. 2014. Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells. J. Lipid Res. 55:1478-88
-
(2014)
J. Lipid Res.
, vol.55
, pp. 1478-1488
-
-
Leamy, A.K.1
Egnatchik, R.A.2
Shiota, M.3
-
24
-
-
34250710450
-
Thematic review series: Adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation
-
Sethi JK, Vidal-Puig AJ. 2007. Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation. J. Lipid Res. 48:1253-62
-
(2007)
J. Lipid Res.
, vol.48
, pp. 1253-1262
-
-
Sethi, J.K.1
Vidal-Puig, A.J.2
-
25
-
-
84939466634
-
Lipodystrophies: Adipose tissue disorders with severe metabolic implications
-
Cortes VA, Fernandez-GalileaM. 2015. Lipodystrophies: adipose tissue disorders with severe metabolic implications. J. Physiol. Biochem. 71:471-78
-
(2015)
J. Physiol. Biochem.
, vol.71
, pp. 471-478
-
-
Cortes, V.A.1
Fernandez-Galilea, M.2
-
26
-
-
84856945930
-
Non-alcoholic fatty liver disease may develop in individuals with normal body mass index
-
Margariti E, Deutsch M, Manolakopoulos S, et al. 2012. Non-alcoholic fatty liver disease may develop in individuals with normal body mass index. Ann. Gastroenterol. 25:45-51
-
(2012)
Ann. Gastroenterol.
, vol.25
, pp. 45-51
-
-
Margariti, E.1
Deutsch, M.2
Manolakopoulos, S.3
-
27
-
-
84947486899
-
Prevalence of non-alcoholic fatty liver disease and steatohepatitis risk factors in patients undergoing bariatric surgery
-
Morita S, De-Santi Neto D, Morita FH, et al. 2015. Prevalence of non-alcoholic fatty liver disease and steatohepatitis risk factors in patients undergoing bariatric surgery. Obes. Surg. 25:2335-43
-
(2015)
Obes. Surg.
, vol.25
, pp. 2335-2343
-
-
Morita, S.1
De-Santi Neto, D.2
Morita, F.H.3
-
29
-
-
84958078771
-
Effect of weight loss, diet, exercise, and bariatric surgery on nonalcoholic fatty liver disease
-
Hannah WN Jr., Harrison SA. 2016. Effect of weight loss, diet, exercise, and bariatric surgery on nonalcoholic fatty liver disease. Clin. Liver Dis. 20(2):339-50
-
(2016)
Clin. Liver Dis.
, vol.20
, Issue.2
, pp. 339-350
-
-
Hannah, W.N.1
Harrison, S.A.2
-
31
-
-
78649695273
-
Regional anthropometric measures and hepatic fibrosis in patients with nonalcoholic fatty liver disease
-
Suzuki A, Abdelmalek MF, Unalp-Arida A, et al. 2010. Regional anthropometric measures and hepatic fibrosis in patients with nonalcoholic fatty liver disease. Clin. Gastroenterol. Hepatol. 8:1062-69
-
(2010)
Clin. Gastroenterol. Hepatol.
, vol.8
, pp. 1062-1069
-
-
Suzuki, A.1
Abdelmalek, M.F.2
Unalp-Arida, A.3
-
32
-
-
36349006497
-
The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome
-
Cheung O, Kapoor A, Puri P, et al. 2007. The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome. Hepatology 46:1091-100
-
(2007)
Hepatology
, vol.46
, pp. 1091-1100
-
-
Cheung, O.1
Kapoor, A.2
Puri, P.3
-
33
-
-
0036239586
-
Body fat distribution in pre-and post-menopausal women: Metabolic and anthropometric variables
-
Garaulet M, Perez-Llamas F, Baraza JC, et al. 2002. Body fat distribution in pre-and post-menopausal women: metabolic and anthropometric variables. J. Nutr. Health Aging 6:123-26
-
(2002)
J. Nutr. Health Aging
, vol.6
, pp. 123-126
-
-
Garaulet, M.1
Perez-Llamas, F.2
Baraza, J.C.3
-
34
-
-
0024232936
-
Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: Predictive equations
-
KvistH, Chowdhury B, Grangard U, et al. 1988. Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations. Am. J. Clin. Nutr. 48:1351-61
-
(1988)
Am. J. Clin. Nutr.
, vol.48
, pp. 1351-1361
-
-
Kvist, H.1
Chowdhury, B.2
Grangard, U.3
-
35
-
-
84976480989
-
A longer duration of estrogen deficiency increases fibrosis risk among postmenopausal women with nonalcoholic fatty liver disease
-
Klair JS, Yang JD, AbdelmalekMF, et al. 2016. A longer duration of estrogen deficiency increases fibrosis risk among postmenopausal women with nonalcoholic fatty liver disease. Hepatology 64(1):85-91
-
(2016)
Hepatology
, vol.64
, Issue.1
, pp. 85-91
-
-
Klair, J.S.1
Yang, J.D.2
Abdelmalek, M.F.3
-
36
-
-
84929206718
-
Nonalcoholic steatohepatitis and hepatic fibrosis in HIV-1-monoinfected adults with elevated aminotransferase levels on antiretroviral therapy
-
Morse CG, McLaughlin M, Matthews L, et al. 2015. Nonalcoholic steatohepatitis and hepatic fibrosis in HIV-1-monoinfected adults with elevated aminotransferase levels on antiretroviral therapy. Clin. Infect. Dis. 60:1569-78
-
(2015)
Clin. Infect. Dis.
, vol.60
, pp. 1569-1578
-
-
Morse, C.G.1
McLaughlin, M.2
Matthews, L.3
-
37
-
-
84963945533
-
Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease
-
Lee PL, Tang Y, Li H, et al. 2016. Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease. Mol. Metab. 5:422-32
-
(2016)
Mol. Metab.
, vol.5
, pp. 422-432
-
-
Lee, P.L.1
Tang, Y.2
Li, H.3
-
38
-
-
48149112155
-
Sirolimus is associated with new-onset diabetes in kidney transplant recipients
-
JohnstonO, Rose CL, Webster AC, et al. 2008. Sirolimus is associated with new-onset diabetes in kidney transplant recipients. J. Am. Soc. Nephrol. 19:1411-18
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 1411-1418
-
-
Johnstono Rose, C.L.1
Webster, A.C.2
-
39
-
-
1542510700
-
Acquired and inherited lipodystrophies
-
Garg A. 2004. Acquired and inherited lipodystrophies. N. Engl. J. Med. 350:1220-34
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1220-1234
-
-
Garg, A.1
-
40
-
-
0346689994
-
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
-
Rinella ME, Green RM. 2004. The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J. Hepatol. 40:47-51
-
(2004)
J. Hepatol.
, vol.40
, pp. 47-51
-
-
Rinella, M.E.1
Green, R.M.2
-
41
-
-
29144509972
-
Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma
-
Watanabe S, Horie Y, Suzuki A. 2005. Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma. Hepatol. Res. 33:161-66
-
(2005)
Hepatol. Res.
, vol.33
, pp. 161-166
-
-
Watanabe, S.1
Horie, Y.2
Suzuki, A.3
-
42
-
-
81355127657
-
Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway
-
Kudo Y, Tanaka Y, Tateishi K, et al. 2011. Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway. J. Hepatol. 55:1400-8
-
(2011)
J. Hepatol.
, vol.55
, pp. 1400-1408
-
-
Kudo, Y.1
Tanaka, Y.2
Tateishi, K.3
-
43
-
-
0015394538
-
Uptake of individual free fatty acids by skeletal muscle and liver in man
-
Hagenfeldt L, Wahren J, Pernow B, et al. 1972. Uptake of individual free fatty acids by skeletal muscle and liver in man. J. Clin. Investig. 51:2324-30
-
(1972)
J. Clin. Investig.
, vol.51
, pp. 2324-2330
-
-
Hagenfeldt, L.1
Wahren, J.2
Pernow, B.3
-
44
-
-
84933039083
-
Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis
-
MachadoMV, Michelotti GA, Pereira de Almeida T, et al. 2015. Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis. Gut 64:1148-57
-
(2015)
Gut
, vol.64
, pp. 1148-1157
-
-
MacHadomv Michelotti, G.A.1
Pereira De Almeida, T.2
-
45
-
-
84888091333
-
Monounsaturated fatty acids generated via stearoylCoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase
-
Liu J, Cinar R, XiongK, et al. 2013. Monounsaturated fatty acids generated via stearoylCoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. PNAS 110:18832-37
-
(2013)
PNAS
, vol.110
, pp. 18832-18837
-
-
Liu, J.1
Cinar, R.2
Xiong, K.3
-
46
-
-
20944436157
-
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
Osei-Hyiaman D, DePetrillo M, Pacher P, et al. 2005. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J. Clin. Investig. 115:1298-305
-
(2005)
J. Clin. Investig.
, vol.115
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
DePetrillo, M.2
Pacher, P.3
-
47
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: Role of stearoyl-CoA desaturase
-
Li ZZ, Berk M, McIntyre TM, et al. 2009. Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase. J. Biol. Chem. 284:5637-44
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
McIntyre, T.M.3
-
48
-
-
84964584427
-
Hepatic oleate regulates liver stress response partially through PGC-1alpha during high-carbohydrate feeding
-
Liu X, Burhans MS, Flowers MT, et al. 2016. Hepatic oleate regulates liver stress response partially through PGC-1alpha during high-carbohydrate feeding. J. Hepatol. 65:103-12
-
(2016)
J. Hepatol.
, vol.65
, pp. 103-112
-
-
Liu, X.1
Burhans, M.S.2
Flowers, M.T.3
-
49
-
-
84941910467
-
Fatty acid and glucose sensors in hepatic lipid metabolism: Implications in NAFLD
-
Vacca M, Allison M, Griffin JL, et al. 2015. Fatty acid and glucose sensors in hepatic lipid metabolism: implications in NAFLD. Semin. Liver Dis. 35:250-61
-
(2015)
Semin. Liver Dis.
, vol.35
, pp. 250-261
-
-
Vacca, M.1
Allison, M.2
Griffin, J.L.3
-
50
-
-
69249113803
-
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control
-
Noland RC, Koves TR, Seiler SE, et al. 2009. Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J. Biol. Chem. 284:22840-52
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 22840-22852
-
-
Noland, R.C.1
Koves, T.R.2
Seiler, S.E.3
-
51
-
-
84885769159
-
Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease
-
Kostapanos MS, Kei A, Elisaf MS. 2013. Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease. World J. Hepatol. 5:470-78
-
(2013)
World J. Hepatol.
, vol.5
, pp. 470-478
-
-
Kostapanos, M.S.1
Kei, A.2
Elisaf, M.S.3
-
52
-
-
77956859765
-
PPARalpha in obesity: Sex difference and estrogen involvement
-
Yoon M. 2010. PPARalpha in obesity: sex difference and estrogen involvement. PPAR Res. 2010:584296
-
(2010)
PPAR Res.
, vol.2010
, pp. 584296
-
-
Yoon, M.1
-
53
-
-
84930004775
-
Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-Noxide
-
Romano KA, Vivas EI, Amador-Noguez D, et al. 2015. Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-Noxide. mBio 6:e02481
-
(2015)
MBio
, vol.6
, pp. e02481
-
-
Romano, K.A.1
Vivas, E.I.2
Amador-Noguez, D.3
-
54
-
-
84942052973
-
An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly
-
McCarty MF, DiNicolantonio JJ. 2015. An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly. Age 37(5):96. doi: 10. 1007/s11357-015-9823-8
-
(2015)
Age
, vol.37
, Issue.5
, pp. 96
-
-
McCarty, M.F.1
DiNicolantonio, J.J.2
-
55
-
-
34248348719
-
Sex and menopausal status influence human dietary requirements for the nutrient choline
-
Fischer LM, daCosta KA, Kwock L, et al. 2007. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am. J. Clin. Nutr. 85:1275-85
-
(2007)
Am. J. Clin. Nutr.
, vol.85
, pp. 1275-1285
-
-
Fischer, L.M.1
DaCosta, K.A.2
Kwock, L.3
-
56
-
-
84925282908
-
Amelioration of lipopolysaccharide-induced liver injury by aqueous rooibos (Aspalathus linearis) extract via inhibition of pro-inflammatory cytokines and oxidative stress
-
Ajuwon OR, Oguntibeju OO, Marnewick JL. 2014. Amelioration of lipopolysaccharide-induced liver injury by aqueous rooibos (Aspalathus linearis) extract via inhibition of pro-inflammatory cytokines and oxidative stress. BMC Complement. Altern. Med. 14:392. doi: 10. 1186/1472-6882-14-392
-
(2014)
BMC Complement. Altern. Med.
, vol.14
, pp. 392
-
-
Ajuwon, O.R.1
Oguntibeju, O.O.2
Marnewick, J.L.3
-
57
-
-
84882827495
-
Decoding cell death signals in liver inflammation
-
Brenner C, Galluzzi L, Kepp O, et al. 2013. Decoding cell death signals in liver inflammation. J. Hepatol. 59:583-94
-
(2013)
J. Hepatol.
, vol.59
, pp. 583-594
-
-
Brenner, C.1
Galluzzi, L.2
Kepp, O.3
-
60
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword
-
Malhotra JD, Kaufman RJ. 2007. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword Antioxidants Redox Signaling 9:2277-93
-
(2007)
Antioxidants Redox Signaling
, vol.9
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
61
-
-
84928183267
-
Death receptor-mediated cell death and proinflammatory signaling in nonalcoholic steatohepatitis
-
Hirsova P, Gores GJ. 2015. Death receptor-mediated cell death and proinflammatory signaling in nonalcoholic steatohepatitis. Cell. Mol. Gastroenterol. Hepatol. 1:17-27
-
(2015)
Cell. Mol. Gastroenterol. Hepatol.
, vol.1
, pp. 17-27
-
-
Hirsova, P.1
Gores, G.J.2
-
62
-
-
0142151769
-
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
-
Canbay A, Feldstein AE, Higuchi H, et al. 2003. Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology 38:1188-98
-
(2003)
Hepatology
, vol.38
, pp. 1188-1198
-
-
Canbay, A.1
Feldstein, A.E.2
Higuchi, H.3
-
63
-
-
77956269092
-
Hepatocellular ballooning in NASH
-
Caldwell S, Ikura Y, Dias D, et al. 2010. Hepatocellular ballooning in NASH. J. Hepatol. 53:719-23
-
(2010)
J. Hepatol.
, vol.53
, pp. 719-723
-
-
Caldwell, S.1
Ikura, Y.2
Dias, D.3
-
64
-
-
78649433367
-
Histopathology of nonalcoholic fatty liver disease
-
Brunt EM, Tiniakos DG. 2010. Histopathology of nonalcoholic fatty liver disease. World J. Gastroenterol. 16:5286-96
-
(2010)
World J. Gastroenterol.
, vol.16
, pp. 5286-5296
-
-
Brunt, E.M.1
Tiniakos, D.G.2
-
65
-
-
84866383427
-
A hedgehog survival pathway in undead" lipotoxic hepatocytes
-
Kakisaka K, Cazanave SC, Werneburg NW, et al. 2012. A hedgehog survival pathway in "undead" lipotoxic hepatocytes. J. Hepatol. 57:844-51
-
(2012)
J. Hepatol.
, vol.57
, pp. 844-851
-
-
Kakisaka, K.1
Cazanave, S.C.2
Werneburg, N.W.3
-
66
-
-
84897928140
-
Caspase-2 mediates a Brucella abortus RB51-induced hybrid cell death having features of apoptosis and pyroptosis
-
Bronner DN, O'Riordan MX, He Y. 2013. Caspase-2 mediates a Brucella abortus RB51-induced hybrid cell death having features of apoptosis and pyroptosis. Front. Cell Infect. Microbiol. Nov. 27(3):83. doi: 10. 3389/fcimb. 2013. 00083
-
(2013)
Front. Cell Infect. Microbiol. Nov.
, vol.27
, Issue.3
, pp. 83
-
-
Bronner, D.N.1
O'Riordan, M.X.2
He, Y.3
-
67
-
-
84989336849
-
ER stress induces NLRP3 inflammasome activation and hepatocyte death
-
Lebeaupin C, Proics E, de Bieville CH, et al. 2015. ER stress induces NLRP3 inflammasome activation and hepatocyte death. Cell Death Dis. 6:e1879
-
(2015)
Cell Death Dis.
, vol.6
, pp. e1879
-
-
Lebeaupin, C.1
Proics, E.2
De Bieville, C.H.3
-
68
-
-
84969142199
-
Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death
-
Sanman LE, Qian Y, Eisele NA, et al. 2016. Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death. eLife 24:5:e13663
-
(2016)
ELife
, vol.24
, Issue.5
, pp. e13663
-
-
Sanman, L.E.1
Qian, Y.2
Eisele, N.A.3
-
69
-
-
84964434465
-
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
-
Zanoni I, Tan Y, Di Gioia M, et al. 2016. An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science 352:1232-36
-
(2016)
Science
, vol.352
, pp. 1232-1236
-
-
Zanoni, I.1
Tan, Y.2
Di Gioia, M.3
-
71
-
-
84949565086
-
Obesity-driven gut microbiota inflammatory pathways to metabolic syndrome
-
Cavalcante-Silva LH, Galvao JG, da Silva JS, et al. 2015. Obesity-driven gut microbiota inflammatory pathways to metabolic syndrome. Front. Physiol. Nov. 19(6):341. doi: 10. 3389/fphys. 2015. 00341
-
(2015)
Front. Physiol. Nov.
, vol.19
, Issue.6
, pp. 341
-
-
Cavalcante-Silva, L.H.1
Galvao, J.G.2
Da Silva, J.S.3
-
72
-
-
84949627236
-
Regulation of metabolism by the innate immune system
-
Lackey DE, Olefsky JM. 2016. Regulation of metabolism by the innate immune system. Nat. Rev. Endocrinol. 12:15-28
-
(2016)
Nat. Rev. Endocrinol.
, vol.12
, pp. 15-28
-
-
Lackey, D.E.1
Olefsky, J.M.2
-
73
-
-
84866520055
-
Adipose tissue invariant NKT cells protect against dietinduced obesity and metabolic disorder through regulatory cytokine production
-
Lynch L, Nowak M, Varghese B, et al. 2012. Adipose tissue invariant NKT cells protect against dietinduced obesity and metabolic disorder through regulatory cytokine production. Immunity 37:574-87
-
(2012)
Immunity
, vol.37
, pp. 574-587
-
-
Lynch, L.1
Nowak, M.2
Varghese, B.3
-
74
-
-
0018861450
-
Cell-mediated immunity in genetically obese (C57BL/6J ob/ob) mice
-
Chandra RK. 1980. Cell-mediated immunity in genetically obese (C57BL/6J ob/ob) mice. Am. J. Clin. Nutr. 33:13-16
-
(1980)
Am. J. Clin. Nutr.
, vol.33
, pp. 13-16
-
-
Chandra, R.K.1
-
75
-
-
23344442120
-
Obesity alters gut microbial ecology
-
Ley RE, Backhed F, Turnbaugh P, et al. 2005. Obesity alters gut microbial ecology. PNAS 102:11070-75
-
(2005)
PNAS
, vol.102
, pp. 11070-11075
-
-
Ley, R.E.1
Backhed, F.2
Turnbaugh, P.3
-
76
-
-
0034005303
-
Altered hepatic lymphocyte subpopulations in obesityrelated murine fatty livers: Potential mechanism for sensitization to liver damage
-
Guebre-Xabier M, Yang S, Lin HZ, et al. 2000. Altered hepatic lymphocyte subpopulations in obesityrelated murine fatty livers: potential mechanism for sensitization to liver damage. Hepatology 31:633-40
-
(2000)
Hepatology
, vol.31
, pp. 633-640
-
-
Guebre-Xabier, M.1
Yang, S.2
Lin, H.Z.3
-
77
-
-
0036288668
-
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver
-
Honda H, Ikejima K, Hirose M, et al. 2002. Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver. Hepatology 36:12-21
-
(2002)
Hepatology
, vol.36
, pp. 12-21
-
-
Honda, H.1
Ikejima, K.2
Hirose, M.3
-
78
-
-
84865041500
-
NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease
-
Syn WK, Agboola KM, Swiderska M, et al. 2012. NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease. Gut 61:1323-29
-
(2012)
Gut
, vol.61
, pp. 1323-1329
-
-
Syn, W.K.1
Agboola, K.M.2
Swiderska, M.3
-
79
-
-
40049104519
-
Natural killer T cells and non-alcoholic fatty liver disease: Fat chews on the immune system
-
Kremer M, Hines IN. 2008. Natural killer T cells and non-alcoholic fatty liver disease: fat chews on the immune system. World J. Gastroenterol. 14:487-88
-
(2008)
World J. Gastroenterol.
, vol.14
, pp. 487-488
-
-
Kremer, M.1
Hines, I.N.2
-
80
-
-
77952730087
-
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease
-
Syn WK, Oo YH, Pereira TA, et al. 2010. Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease. Hepatology 51:1998-2007
-
(2010)
Hepatology
, vol.51
, pp. 1998-2007
-
-
Syn, W.K.1
Oo, Y.H.2
Pereira, T.A.3
-
81
-
-
35948954244
-
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
-
Friedman SL. 2008. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol. Rev. 88:125-72
-
(2008)
Physiol. Rev.
, vol.88
, pp. 125-172
-
-
Friedman, S.L.1
-
82
-
-
84920730709
-
Perivascular Gli1+progenitors are key contributors to injury-induced organ fibrosis
-
KramannR, Schneider RK, DiRocco DP, et al. 2015. Perivascular Gli1+progenitors are key contributors to injury-induced organ fibrosis. Cell Stem Cell 16:51-66
-
(2015)
Cell Stem Cell
, vol.16
, pp. 51-66
-
-
Kramannr Schneider, R.K.1
DiRocco, D.P.2
-
83
-
-
84878527104
-
Smoothened is a master regulator of adult liver repair
-
Michelotti GA, Xie G, Swiderska M, et al. 2013. Smoothened is a master regulator of adult liver repair. J. Clin. Investig. 123:2380-94
-
(2013)
J. Clin. Investig.
, vol.123
, pp. 2380-2394
-
-
Michelotti, G.A.1
Xie, G.2
Swiderska, M.3
-
85
-
-
77951436593
-
Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice
-
Ochoa B, Syn WK, Delgado I, et al. 2010. Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice. Hepatology 51:1712-23
-
(2010)
Hepatology
, vol.51
, pp. 1712-1723
-
-
Ochoa, B.1
Syn, W.K.2
Delgado, I.3
-
86
-
-
70349436007
-
Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease
-
Syn WK, Jung Y, Omenetti A, et al. 2009. Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. Gastroenterology 137:1478-88
-
(2009)
Gastroenterology
, vol.137
, pp. 1478-1488
-
-
Syn, W.K.1
Jung, Y.2
Omenetti, A.3
-
87
-
-
79958229659
-
Increased production of sonic hedgehog by ballooned hepatocytes
-
Rangwala F, Guy CD, Lu J, et al. 2011. Increased production of sonic hedgehog by ballooned hepatocytes. J. Pathol. 224:401-10
-
(2011)
J. Pathol.
, vol.224
, pp. 401-410
-
-
Rangwala, F.1
Guy, C.D.2
Lu, J.3
-
88
-
-
84861573996
-
Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease
-
Guy CD, Suzuki A, Zdanowicz M, et al. 2012. Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease. Hepatology 55:1711-21
-
(2012)
Hepatology
, vol.55
, pp. 1711-1721
-
-
Guy, C.D.1
Suzuki, A.2
Zdanowicz, M.3
-
89
-
-
84920984254
-
Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity
-
Guy CD, Suzuki A, Abdelmalek MF, et al. 2015. Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity. Hepatology 61:98-107
-
(2015)
Hepatology
, vol.61
, pp. 98-107
-
-
Guy, C.D.1
Suzuki, A.2
Abdelmalek, M.F.3
-
90
-
-
84958873649
-
Hepatic expression of SonicHedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model
-
Chung SI, Moon H, Ju HL, et al. 2016. Hepatic expression of SonicHedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model. J. Hepatol. 64:618-27
-
(2016)
J. Hepatol.
, vol.64
, pp. 618-627
-
-
Chung, S.I.1
Moon, H.2
Ju, H.L.3
-
91
-
-
84883051342
-
Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response
-
Myers BR, Sever N, Chong YC, et al. 2013. Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. Dev. Cell 26:346-57
-
(2013)
Dev. Cell
, vol.26
, pp. 346-357
-
-
Myers, B.R.1
Sever, N.2
Chong, Y.C.3
-
92
-
-
73349130440
-
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate
-
Pospisilik JA, Schramek D, Schnidar H, et al. 2010. Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell 140:148-60
-
(2010)
Cell
, vol.140
, pp. 148-160
-
-
Pospisilik, J.A.1
Schramek, D.2
Schnidar, H.3
-
93
-
-
84867536639
-
Hedgehog partial agonism drives Warburg-likemetabolism in muscle and brown fat
-
Teperino R, Amann S, BayerM, et al. 2012. Hedgehog partial agonism drives Warburg-likemetabolism in muscle and brown fat. Cell 151:414-26
-
(2012)
Cell
, vol.151
, pp. 414-426
-
-
Teperino, R.1
Amann, S.2
Bayer, M.3
-
94
-
-
84900328675
-
A form of the metabolic syndrome associated with mutations in DYRK1B
-
Keramati AR, Fathzadeh M, Go GW, et al. 2014. A form of the metabolic syndrome associated with mutations in DYRK1B. N. Engl. J. Med. 370:1909-19
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 1909-1919
-
-
Keramati, A.R.1
Fathzadeh, M.2
Go, G.W.3
-
95
-
-
84938149040
-
14-3-3 coordinates adipogenesis of visceral fat
-
Lim GE, Albrecht T, Piske M, et al. 2015. 14-3-3 coordinates adipogenesis of visceral fat. Nat.commun. 6:7671
-
(2015)
Nat.commun.
, vol.6
, pp. 7671
-
-
Lim, G.E.1
Albrecht, T.2
Piske, M.3
-
96
-
-
84949293913
-
The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGF/BMP and hypoxia pathways
-
Borggrefe T, Lauth M, Zwijsen A, et al. 2016. The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGF/BMP and hypoxia pathways. Biochim. Biophys. Acta. 1863:303-13
-
(2016)
Biochim. Biophys. Acta.
, vol.1863
, pp. 303-313
-
-
Borggrefe, T.1
Lauth, M.2
Zwijsen, A.3
-
97
-
-
84927925164
-
Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation
-
Shi Y, Chen J, Karner CM, et al. 2015. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. PNAS 112:4678-83
-
(2015)
PNAS
, vol.112
, pp. 4678-4683
-
-
Shi, Y.1
Chen, J.2
Karner, C.M.3
-
98
-
-
84898715615
-
The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
-
Varelas X. 2014. The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease. Development 141:1614-26
-
(2014)
Development
, vol.141
, pp. 1614-1626
-
-
Varelas, X.1
-
99
-
-
84930486078
-
Signaling networks organizing regenerative growth of the zebrafish fin
-
Wehner D, Weidinger G. 2015. Signaling networks organizing regenerative growth of the zebrafish fin. Trends Genet. 31:336-43
-
(2015)
Trends Genet.
, vol.31
, pp. 336-343
-
-
Wehner, D.1
Weidinger, G.2
-
100
-
-
84978615262
-
Phosphatase and tensin homologue: Novel regulation by developmental signaling
-
Jerde TJ. 2015. Phosphatase and tensin homologue: novel regulation by developmental signaling. J. Signal Transduct. 2015:282567. doi: 10. 1155/2015/282567
-
(2015)
J. Signal Transduct.
, vol.2015
, pp. 282567
-
-
Jerde, T.J.1
|