Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease

Molecular Metabolism

Volumn 5, Issue 6, 2016, Pages 422-432

  Lee, Peter L ^a   Tang, Yuefeng ^a   Li, Huawei ^a   Guertin, David A ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Lipodystrophy; MTORC1; Obesity; Rapamycin; Raptor; White Adipose Tissue (WAT)

Indexed keywords

ADIPONECTIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CRE RECOMBINASE; GROWTH FACTOR; MAMMALIAN TARGET OF RAPAMYCIN;

ADIPOCYTE; ADIPONECTIN CRE GENE; ADIPOSE TISSUE; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CELL METABOLISM; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENERGY EXPENDITURE; FATTY LIVER; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOSS; HEPATOMEGALY; HUMAN; HUMAN TISSUE; HYPERPHAGIA; INSULIN RESISTANCE; LIPID ABSORPTION; LIPID ABSORPTION DEFECT; LIPODYSTROPHY; LIPOLYSIS; MALE; MTORC1 GENE; NONHUMAN; NUTRIENT; NUTRIENT AVAILABILITY; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAPTOR; TISSUE EXPANSION; TISSUE GROWTH; WEIGHT, MASS AND SIZE; WHITE ADIPOSE TISSUE;

EID: 84963945533     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2016.04.001     Document Type: Article

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