Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway

Journal of Hepatology

Volumn 55, Issue 6, 2011, Pages 1400-1408

  Kudo, Yotaro ^a   Tanaka, Yasuo ^a   Tateishi, Keisuke ^a   Yamamoto, Keisuke ^a   Yamamoto, Shinzo ^a   Mohri, Dai ^a   Isomura, Yoshihiro ^a   Seto, Motoko ^a   Nakagawa, Hayato ^a   Asaoka, Yoshinari ^a   Tada, Motohisa ^b   Ohta, Miki ^a   Ijichi, Hideaki ^a   Hirata, Yoshihiro ^a   Otsuka, Motoyuki ^a   Ikenoue, Tsuneo ^a   Maeda, Shin ^c   Shiina, Shuichiro ^a   Yoshida, Haruhiko ^a   Nakajima, Osamu ^d   Kanai, Fumihiko ^b   Omata, Masao ^e   Koike, Kazuhiko ^a   more..

^a UNIVERSITY OF TOKYO   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d YAMAGATA UNIVERSITY   (Japan)

^e Yamanashi Prefectural Central Hospital   (Japan)

Author keywords

Fatty acids; Hepatocellular carcinoma; NAFLD; Tumor suppressor genes

Indexed keywords

DLC1 PROTEIN; FATTY ACID; MAMMALIAN TARGET OF RAPAMYCIN; OLEIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; XPO4 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL IMMORTALIZATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FATTY LIVER; GENE EXPRESSION; GENE MUTATION; LIPID COMPOSITION; LIPOGENESIS; LIVER CARCINOGENESIS; LIVER CELL; METABOLIC REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DOWN-REGULATION; ENZYME ACTIVATION; FATTY ACIDS; FATTY LIVER; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; HEPATOCYTES; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTANT PROTEINS; OLEIC ACIDS; PALMITIC ACIDS; PHOSPHATIDYLINOSITOL 3-KINASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 81355127657     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.03.025     Document Type: Article

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