Prevalence of Non-alcoholic Fatty Liver Disease and Steatohepatitis Risk Factors in Patients Undergoing Bariatric Surgery

Obesity Surgery

Volumn 25, Issue 12, 2015, Pages 2335-2343

  Morita, Shinhiti ^a,c   Neto, Dalísio De Santi ^b   Morita, Flávio Hiroshi Ananias ^a   Morita, Nina Kimie ^a   Lobo, Suzana Margareth Ajeje ^a  

^a HOSPITAL DE BASE   (Brazil)

^b Pathology Department   (Brazil)

^c NONE   (Brazil)

Author keywords

Morbid obesity; Non alcoholic fatty liver disease; Steatohepatitis; Steatosis

Indexed keywords

ALANINE AMINOTRANSFERASE; TRIACYLGLYCEROL;

ADULT; AGE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BARIATRIC SURGERY; BIOPSY NEEDLE; CLINICAL EVALUATION; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; HEALTH CARE COST; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INDEPENDENT VARIABLE; LIVER BIOPSY; MAJOR CLINICAL STUDY; MALE; MORBID OBESITY; NONALCOHOLIC FATTY LIVER; PREDICTIVE VALUE; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SURGICAL PATIENT; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; BLOOD; COMPLICATION; FATTY LIVER; LIVER CIRRHOSIS; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY, MORBID; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

ADULT; ALANINE TRANSAMINASE; BARIATRIC SURGERY; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FATTY LIVER; FEMALE; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY, MORBID; PREVALENCE; RISK FACTORS;

EID: 84947486899     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-015-1696-5     Document Type: Article

References (36)

1. Dixon JB, Bhatal PS, Obrien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in severely obese. Gastroenterology. 2001;121(1):91–100.
2. Festi D, Colecchia A, Sacco T, et al. Hepatic steatosis in obese patients: clinical aspects and prognostic significance. Obes Rev. 2004;5(1):27–42.
3. Marchesini G, Brizi M, Bianchi G, et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes. 2001;50(8):1844–50.
4. Dixon JB, Bhatal PS, Hughes NR, et al. Nonalcoholic fatty liver disease: improvement in liver histological analysis with weight loss. Hepatology. 2004;39(6):1647–54.
5. Levene AP, Goldin RD. The epidemiology, pathogenesis and histopathology of fatty liver disease. Histopathology. 2012;61(2):141–52. doi:10.1111/j.1365-2559.2011.04145.x.
6. Brunt EM, Tiniakos DG. Pathology of nonalcoholic fatty liver disease. World J Gastroenterol. 2010;16(42):5286–96.
7. Holterman AX, Guzman G, Fantuzzi G, et al. Nonalcoholic fatty liver disease in severely obese adolescent and adult patients. Obesity (Silver Spring). 2013;21(3):591–7. doi:10.1002/oby.20174.
8. Tacer KF, Rozman D. Nonalcoholic fatty liver disease: focus on lipoprotein and lipid deregulation. J Lipids. 2011. http://www.hindawi.com/journals/jl/2011/783976/.
9. Day CP, James OF. Steatohepatitis: a tale of two hits. Gastroenterology. 1998;114(4):842–5.
10. Machado M, Marques-Vidal P, Cortez-Pinto H. Hepatic histology in obese patients undergoing bariatric surgery. J Hepatol. 2006;45(4):600–6.
11. Sanyal AJ, Brunt EM, Kleiner DE, et al. Endpoints and clinical trial design for nonalcoholic steatohepatitis. Hepatology. 2011;54(1):344–53. doi:10.1002/hep.24376.
12. Marceau P, Biron S, Hould FS, et al. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab. 1999;84(5):1513–7.
13. Capella RF, Capella JF, Mandec H, et al. Vertical banded gastroplasty-gastric bypass: preliminary report. Obes Surg. 1991;1(4):389–95.
14. Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology. 2003;37(5):1202–19.
15. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–9.
16. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adult (Adult Treatment Panel III). JAMA. 2001;285(19):2486–97.
17. Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41(6):1313–21.
18. Campos GM, Bambh K, Vittinghoff E, et al. A clinical scoring system for predicting nonalcoholic steatohepatitis in morbidly obese patients. Hepatology. 2008;47(6):1916–23. doi:10.1002/hep.22241.
19. Mathurin P, Hollebecque A, Arnalsteen L, et al. Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease. Gastroenterology. 2009;137(2):532–40. doi:10.1053/j.gastro.2009.04.052.
20. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287(3):356–9.
21. Marchesini G, Bugianesi E, Forlani G, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology. 2003;37(4):917–23.
22. Wolf AM, Busch BB, Kuhlmann HW, et al. Histological changes in the liver of morbidly obese patients: correlation with metabolic parameters. Obes Surg. 2005;15(2):228–37.
23. Penninx BWJH, Nicklas BJ, Newman AB, et al. Metabolic syndrome and physical decline in older persons: results from the Health, Aging and Body Composition Study. J Gerontol A Biol Sci Med. 2009;64A(1):96–102.
24. Souza MRA, Diniz MFFM, Medeiros-Filho MJEM, et al. Metabolic syndrome and risk factors for non-alcoholic fatty liver disease. Arq Gastroenterol. 2012;49(1):89–96.
25. Luyckx FH, Desaive C, Thiry A, et al. Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty. Int J Obes Relat Metab Disord. 1998;22(3):222–6.
26. Feijo SG, Lima JMC, Oliveira MAA, et al. The spectrum of non alcoholic fatty liver disease in morbidly obese patients. Prevalence and associate risk factors. Acta Cir Bras. 2013;28(11):788–93.
27. Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, et al. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gama ligand rosiglitazone. Hepatology. 2003;38(4):1008–17.
28. Brunt E, Janney CG, Di Bisceglie AM, et al. Nonalcoholic Steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol. 1999;94(9):2467–74.
29. Schwenger KJP, Allard JP. Clinical approaches to non-alcoholic fatty liver disease. World J Gastroenterol. 2014;20(7):1712–23.
30. Sobhonslidsuk A, Jongjirasiri S, Thakkinstian A, et al. Visceral fat and insulin resistance as predictors of non-alcoholic steatohepatitis. World J Gastroenterol. 2007;13(26):3614–8.
31. Purcell M, Flores YN, Zhang ZF, et al. Prevalence and predictors of alanine aminotransferase elevation among normal weight, overweight and obese youth in Mexico. J Dig Dis. 2013;14(9):491–9. doi:10.1111/1751-2980.12072.
32. Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol. 2003;98(5):960–7.
33. Bedossa P, Poitou C, Veyrie N, et al. Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients. Hepatology. 2012;56(5):1751–9. doi:10.1002/hep.25889.
34. Bass NM, Brunt EM, Clark JM, et al. Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease. Hepatology. 2010;52(3):913–24.
35. De K, Berk PD, Hsu JY, et al. Hepatic pathology among patients without known liver disease undergoing bariatric surgery: observations and a perspective from the Longitudinal Assessment of Bariatric Surgery (LABS) Study. Semin Liver Dis. 2014;34(1):98–107. doi:10.1055/s-0034-1371083.
36. Cotrim HP, Parise ER, Oliveira CP, et al. Nonalcoholic fatty liver disease in Brazil. Clinical and Histological profile. Ann Hepatol. 2011;10(1):33–7.