A hedgehog survival pathway in 'undead' lipotoxic hepatocytes

Journal of Hepatology

Volumn 57, Issue 4, 2012, Pages 844-851

  Kakisaka, Keisuke ^a   Cazanave, Sophie C ^a   Werneburg, Nathan W ^a   Razumilava, Nataliya ^a   Mertens, Joachim C ^a   Bronk, Steve F ^a   Gores, Gregory J ^a  

^a MAYO CLINIC   (United States)

Author keywords

c Jun N terminal kinase (JNK); Caspase 3; Lipoapoptosis; Lysophosphatidylcholine; Palmitate

Indexed keywords

CASPASE 3; CASPASE 9; FAT DROPLET; LYSOPHOSPHATIDYLCHOLINE; PALMITIC ACID; SHORT HAIRPIN RNA; SONIC HEDGEHOG PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR GLI2;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIPOTOXICITY; LIVER CELL; MITOCHONDRION; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CASPASE 1; CASPASE 9; CELL LINE, TUMOR; DOWN-REGULATION; FATTY LIVER; GENE KNOCKDOWN TECHNIQUES; HEDGEHOG PROTEINS; HEPATOCYTES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYSOPHOSPHATIDYLCHOLINES; MINUTE VIRUS OF MICE; PALMITATES; PHOSPHORYLATION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 84866383427     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.05.011     Document Type: Article

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