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Volumn 13, Issue , 2016, Pages S429-S437

Is chronic obstructive pulmonary disease an accelerated aging disease?

Author keywords

Aging; Chronic obstructive pulmonary disease; Chronic obstructive pulmonary disease pathogenesis immunosenescence

Indexed keywords

AGING; CELL AGING; CELL COMMUNICATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFERENCE PAPER; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPIGENETICS; GENOMIC INSTABILITY; HUMAN; NONHUMAN; NUTRIENT; PROTEIN HOMEOSTASIS; SENESCENCE; STEM CELL; TELOMERE; ADAPTIVE IMMUNITY; IMMUNOLOGY; IMMUNOSENESCENCE; INFLAMMATION; INNATE IMMUNITY; LUNG; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; TELOMERE SHORTENING;

EID: 85008325111     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201602-124AW     Document Type: Conference Paper
Times cited : (103)

References (90)
  • 1
    • 13944262937 scopus 로고    scopus 로고
    • Understanding the odd science of aging
    • Kirkwood TB. Understanding the odd science of aging. Cell 2005;120: 437-447.
    • (2005) Cell , vol.120 , pp. 437-447
    • Kirkwood, T.B.1
  • 3
    • 84891429025 scopus 로고    scopus 로고
    • The good and the bad of being connected: The integrons of aging
    • Dillin A, Gottschling DE, Nyström T. The good and the bad of being connected: the integrons of aging. Curr Opin Cell Biol 2014;26: 107-112.
    • (2014) Curr Opin Cell Biol , vol.26 , pp. 107-112
    • Dillin, A.1    Gottschling, D.E.2    Nyström, T.3
  • 4
    • 50649101095 scopus 로고    scopus 로고
    • Puzzles, promises and a cure for ageing
    • Vijg J, Campisi J. Puzzles, promises and a cure for ageing. Nature 2008;454:1065-1071.
    • (2008) Nature , vol.454 , pp. 1065-1071
    • Vijg, J.1    Campisi, J.2
  • 5
    • 0000055057 scopus 로고
    • Pleiotropy, natural selection, and the evolution of senescence
    • Williams GC. Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957;11:398-411.
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 6
    • 77955722198 scopus 로고    scopus 로고
    • Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program
    • Blagosklonny MV. Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program. Cell Cycle 2010;9: 3151-3156.
    • (2010) Cell Cycle , vol.9 , pp. 3151-3156
    • Blagosklonny, M.V.1
  • 7
    • 0017782437 scopus 로고
    • Evolution of ageing
    • Kirkwood TB. Evolution of ageing. Nature 1977;270:301-304.
    • (1977) Nature , vol.270 , pp. 301-304
    • Kirkwood, T.B.1
  • 8
    • 33744478401 scopus 로고    scopus 로고
    • Free radical theory of aging: An update: Increasing the functional life span
    • Harman D. Free radical theory of aging: an update: increasing the functional life span. Ann N Y Acad Sci 2006;1067:10-21.
    • (2006) Ann N y Acad Sci , vol.1067 , pp. 10-21
    • Harman, D.1
  • 9
    • 79952659906 scopus 로고    scopus 로고
    • The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan
    • Speakman JR, Selman C. The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan. Bioessays 2011;33:255-259.
    • (2011) Bioessays , vol.33 , pp. 255-259
    • Speakman, J.R.1    Selman, C.2
  • 10
    • 80053124673 scopus 로고    scopus 로고
    • Taking a "good" look at free radicals in the aging process
    • Hekimi S, Lapointe J, Wen Y. Taking a "good" look at free radicals in the aging process. Trends Cell Biol 2011;21:569-576.
    • (2011) Trends Cell Biol , vol.21 , pp. 569-576
    • Hekimi, S.1    Lapointe, J.2    Wen, Y.3
  • 11
    • 84906656463 scopus 로고    scopus 로고
    • The mitochondrial free radical theory of aging
    • Barja G. The mitochondrial free radical theory of aging. Prog Mol Biol Transl Sci 2014;127:1-27.
    • (2014) Prog Mol Biol Transl Sci , vol.127 , pp. 1-27
    • Barja, G.1
  • 12
    • 33750620057 scopus 로고    scopus 로고
    • Oxidative stress and redox regulation of lung inflammation in COPD
    • Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 2006;28:219-242.
    • (2006) Eur Respir J , vol.28 , pp. 219-242
    • Rahman, I.1    Adcock, I.M.2
  • 13
    • 16344376370 scopus 로고    scopus 로고
    • Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity
    • De Martinis M, Franceschi C, Monti D, Ginaldi L. Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett 2005;579:2035-2039.
    • (2005) FEBS Lett , vol.579 , pp. 2035-2039
    • De Martinis, M.1    Franceschi, C.2    Monti, D.3    Ginaldi, L.4
  • 14
    • 84865121012 scopus 로고    scopus 로고
    • Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
    • Faner R, Rojas M, MacNee W, Agustí A. Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2012;186:306-313.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 306-313
    • Faner, R.1    Rojas, M.2    MacNee, W.3    Agustí, A.4
  • 15
    • 0017402583 scopus 로고
    • The natural history of chronic airflow obstruction
    • Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ 1977;1:1645-1648.
    • (1977) BMJ , vol.1 , pp. 1645-1648
    • Fletcher, C.1    Peto, R.2
  • 16
    • 84858020392 scopus 로고    scopus 로고
    • Respiratory impairment and the aging lung: A novel paradigm for assessing pulmonary function
    • Vaz Fragoso CA, Gill TM. Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function. J Gerontol A Biol Sci Med Sci 2012;67:264-275.
    • (2012) J Gerontol A Biol Sci Med Sci , vol.67 , pp. 264-275
    • Vaz Fragoso, C.A.1    Gill, T.M.2
  • 17
    • 28744440976 scopus 로고    scopus 로고
    • Aging of the respiratory system: Impact on pulmonary function tests and adaptation to exertion
    • vi-vii
    • Janssens JP. Aging of the respiratory system: impact on pulmonary function tests and adaptation to exertion. Clin Chest Med 2005;26: 469-484, vi-vii.
    • (2005) Clin Chest Med , vol.26 , pp. 469-484
    • Janssens, J.P.1
  • 18
    • 0027235796 scopus 로고
    • Effect of aging on respiratory skeletal muscles
    • Tolep K, Kelsen SG. Effect of aging on respiratory skeletal muscles. Clin Chest Med 1993;14:363-378.
    • (1993) Clin Chest Med , vol.14 , pp. 363-378
    • Tolep, K.1    Kelsen, S.G.2
  • 26
    • 84923136283 scopus 로고    scopus 로고
    • Animal models of aging research: Implications for human aging and agerelated diseases
    • Mitchell SJ, Scheibye-Knudsen M, Longo DL, de Cabo R. Animal models of aging research: implications for human aging and agerelated diseases. Annu Rev Anim Biosci 2015;3:283-303.
    • (2015) Annu Rev Anim Biosci , vol.3 , pp. 283-303
    • Mitchell, S.J.1    Scheibye-Knudsen, M.2    Longo, D.L.3    De Cabo, R.4
  • 29
    • 84861865579 scopus 로고    scopus 로고
    • DNA damage as a molecular link in the pathogenesis of COPD in smokers
    • Aoshiba K, Zhou F, Tsuji T, Nagai A. DNA damage as a molecular link in the pathogenesis of COPD in smokers. Eur Respir J 2012;39: 1368-1376.
    • (2012) Eur Respir J , vol.39 , pp. 1368-1376
    • Aoshiba, K.1    Zhou, F.2    Tsuji, T.3    Nagai, A.4
  • 31
    • 33749534161 scopus 로고    scopus 로고
    • Telomeres and telomerase: The path from maize, Tetrahymena and yeast to human cancer and aging
    • Blackburn EH, Greider CW, Szostak JW. Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med 2006;12:1133-1138.
    • (2006) Nat Med , vol.12 , pp. 1133-1138
    • Blackburn, E.H.1    Greider, C.W.2    Szostak, J.W.3
  • 32
    • 0036236630 scopus 로고    scopus 로고
    • Replicative aging, telomeres, and oxidative stress
    • Saretzki G, Von Zglinicki T. Replicative aging, telomeres, and oxidative stress. Ann N Y Acad Sci 2002;959:24-29.
    • (2002) Ann N y Acad Sci , vol.959 , pp. 24-29
    • Saretzki, G.1    Von Zglinicki, T.2
  • 33
    • 84878931597 scopus 로고    scopus 로고
    • Telomere length behaves as biomarker of somatic redundancy rather than biological age
    • Boonekamp JJ, Simons MJ, Hemerik L, Verhulst S. Telomere length behaves as biomarker of somatic redundancy rather than biological age. Aging Cell 2013;12:330-332.
    • (2013) Aging Cell , vol.12 , pp. 330-332
    • Boonekamp, J.J.1    Simons, M.J.2    Hemerik, L.3    Verhulst, S.4
  • 37
    • 33749841717 scopus 로고    scopus 로고
    • Alveolar cell senescence in patients with pulmonary emphysema
    • Tsuji T, Aoshiba K, Nagai A. Alveolar cell senescence in patients with pulmonary emphysema. Am J Respir Crit Care Med 2006;174: 886-893.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 886-893
    • Tsuji, T.1    Aoshiba, K.2    Nagai, A.3
  • 39
    • 77953812712 scopus 로고    scopus 로고
    • Alveolar cell senescence exacerbates pulmonary inflammation in patients with chronic obstructive pulmonary disease
    • Tsuji T, Aoshiba K, Nagai A. Alveolar cell senescence exacerbates pulmonary inflammation in patients with chronic obstructive pulmonary disease. Respiration 2010;80:59-70.
    • (2010) Respiration , vol.80 , pp. 59-70
    • Tsuji, T.1    Aoshiba, K.2    Nagai, A.3
  • 41
    • 84876290428 scopus 로고    scopus 로고
    • Short telomere length, lung function and chronic obstructive pulmonary disease in 46, 396 individuals
    • Rode L, Bojesen SE, Weischer M, Vestbo J, Nordestgaard BG. Short telomere length, lung function and chronic obstructive pulmonary disease in 46, 396 individuals. Thorax 2013;68:429-435.
    • (2013) Thorax , vol.68 , pp. 429-435
    • Rode, L.1    Bojesen, S.E.2    Weischer, M.3    Vestbo, J.4    Nordestgaard, B.G.5
  • 45
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005;120:513-522.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 47
    • 9744272376 scopus 로고    scopus 로고
    • Cigarette smoke induces senescence in alveolar epithelial cells
    • Tsuji T, Aoshiba K, Nagai A. Cigarette smoke induces senescence in alveolar epithelial cells. Am J Respir Cell Mol Biol 2004;31:643-649.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 643-649
    • Tsuji, T.1    Aoshiba, K.2    Nagai, A.3
  • 52
    • 42649146208 scopus 로고    scopus 로고
    • SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease
    • Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008;177:861-870.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 861-870
    • Rajendrasozhan, S.1    Yang, S.R.2    Kinnula, V.L.3    Rahman, I.4
  • 53
    • 79956218469 scopus 로고    scopus 로고
    • Epigenetic control of gene expression in the lung
    • Yang IV, Schwartz DA. Epigenetic control of gene expression in the lung. Am J Respir Crit Care Med 2011;183:1295-1301.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1295-1301
    • Yang, I.V.1    Schwartz, D.A.2
  • 54
    • 34248208217 scopus 로고    scopus 로고
    • Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity
    • Harms KL, Chen X. Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity. Cancer Res 2007;67:3145-3152.
    • (2007) Cancer Res , vol.67 , pp. 3145-3152
    • Harms, K.L.1    Chen, X.2
  • 57
    • 84892363964 scopus 로고    scopus 로고
    • Histone deacetylases and their inhibitors: New implications for asthma and chronic respiratory conditions
    • Royce SG, Karagiannis TC. Histone deacetylases and their inhibitors: new implications for asthma and chronic respiratory conditions. Curr Opin Allergy Clin Immunol 2014;14:44-48.
    • (2014) Curr Opin Allergy Clin Immunol , vol.14 , pp. 44-48
    • Royce, S.G.1    Karagiannis, T.C.2
  • 59
    • 79960652801 scopus 로고    scopus 로고
    • Molecular chaperones in protein folding and proteostasis
    • Hartl FU, Bracher A, Hayer-Hartl M. Molecular chaperones in protein folding and proteostasis. Nature 2011;475:324-332.
    • (2011) Nature , vol.475 , pp. 324-332
    • Hartl, F.U.1    Bracher, A.2    Hayer-Hartl, M.3
  • 60
    • 70349507340 scopus 로고    scopus 로고
    • The shock of aging: Molecular chaperones and the heat shock response in longevity and aging - A mini-review
    • Calderwood SK, Murshid A, Prince T. The shock of aging: molecular chaperones and the heat shock response in longevity and aging - a mini-review. Gerontology 2009;55:550-558.
    • (2009) Gerontology , vol.55 , pp. 550-558
    • Calderwood, S.K.1    Murshid, A.2    Prince, T.3
  • 62
    • 84863536630 scopus 로고    scopus 로고
    • What shall we do with the damaged proteins in lung disease? Ask the proteasome
    • Meiners S, Eickelberg O. What shall we do with the damaged proteins in lung disease? Ask the proteasome! Eur Respir J 2012;40: 1260-1268.
    • (2012) Eur Respir J , vol.40 , pp. 1260-1268
    • Meiners, S.1    Eickelberg, O.2
  • 63
    • 61649103107 scopus 로고    scopus 로고
    • Autophagy in chronic obstructive pulmonary disease: Homeostatic or pathogenic mechanism
    • Ryter SW, Chen ZH, Kim HP, Choi AM. Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism? Autophagy 2009;5:235-237.
    • (2009) Autophagy , vol.5 , pp. 235-237
    • Ryter, S.W.1    Chen, Z.H.2    Kim, H.P.3    Choi, A.M.4
  • 65
    • 84875892111 scopus 로고    scopus 로고
    • Autophagy as a stress-response and qualitycontrol mechanism: Implications for cell injury and human disease
    • Murrow L, Debnath J. Autophagy as a stress-response and qualitycontrol mechanism: implications for cell injury and human disease. Annu Rev Pathol 2013;8:105-137.
    • (2013) Annu Rev Pathol , vol.8 , pp. 105-137
    • Murrow, L.1    Debnath, J.2
  • 67
    • 84912528393 scopus 로고    scopus 로고
    • MTOR and autophagy: A dynamic relationship governed by nutrients and energy
    • Dunlop EA, Tee AR. mTOR and autophagy: a dynamic relationship governed by nutrients and energy. Semin Cell Dev Biol 2014;36:121-129.
    • (2014) Semin Cell Dev Biol , vol.36 , pp. 121-129
    • Dunlop, E.A.1    Tee, A.R.2
  • 68
    • 84859508650 scopus 로고    scopus 로고
    • Defective phagocytosis in airways disease
    • Donnelly LE, Barnes PJ. Defective phagocytosis in airways disease. Chest 2012;141:1055-1062.
    • (2012) Chest , vol.141 , pp. 1055-1062
    • Donnelly, L.E.1    Barnes, P.J.2
  • 69
    • 84872527628 scopus 로고    scopus 로고
    • MTOR is a key modulator of ageing and age-related disease
    • Johnson SC, Rabinovitch PS, Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature 2013;493:338-345.
    • (2013) Nature , vol.493 , pp. 338-345
    • Johnson, S.C.1    Rabinovitch, P.S.2    Kaeberlein, M.3
  • 70
    • 84872899284 scopus 로고    scopus 로고
    • FOXOs: Signalling integrators for homeostasis maintenance
    • Eijkelenboom A, Burgering BMT. FOXOs: signalling integrators for homeostasis maintenance. Nat Rev Mol Cell Biol 2013;14:83-97.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 83-97
    • Eijkelenboom, A.1    Burgering, B.M.T.2
  • 72
    • 79960527353 scopus 로고    scopus 로고
    • FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease
    • Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I. FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease. J Immunol 2011;187:987-998.
    • (2011) J Immunol , vol.187 , pp. 987-998
    • Hwang, J.W.1    Rajendrasozhan, S.2    Yao, H.3    Chung, S.4    Sundar, I.K.5    Huyck, H.L.6    Pryhuber, G.S.7    Kinnula, V.L.8    Rahman, I.9
  • 73
    • 84872687212 scopus 로고    scopus 로고
    • Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A
    • Ganesan S, Unger BL, Comstock AT, Angel KA, Mancuso P, Martinez FJ, Sajjan US. Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A. Thorax 2013;68:131-141.
    • (2013) Thorax , vol.68 , pp. 131-141
    • Ganesan, S.1    Unger, B.L.2    Comstock, A.T.3    Angel, K.A.4    Mancuso, P.5    Martinez, F.J.6    Sajjan, U.S.7
  • 74
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005;120:483-495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 75
    • 84891679916 scopus 로고    scopus 로고
    • Targeting mitochondrial dysfunction in lung diseases: Emphasis on mitophagy
    • Sureshbabu A, Bhandari V. Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy. Front Physiol 2013;4:384.
    • (2013) Front Physiol , vol.4 , pp. 384
    • Sureshbabu, A.1    Bhandari, V.2
  • 81
    • 84873608154 scopus 로고    scopus 로고
    • Mechanisms that regulate stem cell aging and life span
    • Signer RAJ, Morrison SJ. Mechanisms that regulate stem cell aging and life span. Cell Stem Cell 2013;12:152-165.
    • (2013) Cell Stem Cell , vol.12 , pp. 152-165
    • Signer, R.A.J.1    Morrison, S.J.2
  • 82
    • 84896820403 scopus 로고    scopus 로고
    • Basal cell origins of smoking-induced airway epithelial disorders
    • Shaykhiev R, Crystal RG. Basal cell origins of smoking-induced airway epithelial disorders. Cell Cycle 2014;13:341-342.
    • (2014) Cell Cycle , vol.13 , pp. 341-342
    • Shaykhiev, R.1    Crystal, R.G.2
  • 84
    • 84890451565 scopus 로고    scopus 로고
    • Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence
    • Paschalaki KE, Starke RD, Hu Y, Mercado N, Margariti A, Gorgoulis VG, Randi AM, Barnes PJ. Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence. Stem Cells 2013;31: 2813-2826.
    • (2013) Stem Cells , vol.31 , pp. 2813-2826
    • Paschalaki, K.E.1    Starke, R.D.2    Hu, Y.3    Mercado, N.4    Margariti, A.5    Gorgoulis, V.G.6    Randi, A.M.7    Barnes, P.J.8
  • 88
    • 35148862090 scopus 로고    scopus 로고
    • The immunopathogenesis of chronic obstructive pulmonary disease: Insights from recent research
    • Curtis JL, Freeman CM, Hogg JC. The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research. Proc Am Thorac Soc 2007;4:512-521.
    • (2007) Proc Am Thorac Soc , vol.4 , pp. 512-521
    • Curtis, J.L.1    Freeman, C.M.2    Hogg, J.C.3
  • 89
    • 80052706801 scopus 로고    scopus 로고
    • New insights into the immunology of chronic obstructive pulmonary disease
    • Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011;378:1015-1026.
    • (2011) Lancet , vol.378 , pp. 1015-1026
    • Brusselle, G.G.1    Joos, G.F.2    Bracke, K.R.3
  • 90
    • 77958148045 scopus 로고    scopus 로고
    • The role of immunity and inflammation in lung senescence and susceptibility to infection in the elderly
    • Meyer KC. The role of immunity and inflammation in lung senescence and susceptibility to infection in the elderly. Semin Respir Crit Care Med 2010;31:561-574.
    • (2010) Semin Respir Crit Care Med , vol.31 , pp. 561-574
    • Meyer, K.C.1


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