-
1
-
-
84863511356
-
Proteostasis, an emerging therapeutic paradigm for managing inflammatory airway stress disease
-
Bouchecareilh M, Balch WE. Proteostasis, an emerging therapeutic paradigm for managing inflammatory airway stress disease. Curr Mol Med 2012; 12:815-826
-
(2012)
Curr Mol Med
, vol.12
, pp. 815-826
-
-
Bouchecareilh, M.1
Balch, W.E.2
-
2
-
-
78649905409
-
Histone deacetylase inhibitors: A chemical genetics approach to understanding cellular functions
-
Marks PA. Histone deacetylase inhibitors: A chemical genetics approach to understanding cellular functions. Biochim Biophys Acta 2010; 1799:717-725
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 717-725
-
-
Marks, P.A.1
-
3
-
-
77955643796
-
The clinical development of histone deacetylase inhibitors as targeted anticancer drugs
-
Marks PA. The clinical development of histone deacetylase inhibitors as targeted anticancer drugs. Expert Opin Investig Drugs 2010; 19:1049-1066
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 1049-1066
-
-
Marks, P.A.1
-
4
-
-
84868653794
-
Histone deacetylase inhibitors: Can we consider potent antineoplastic agents for the treatment of asthma?
-
Royce SG, Ververis K, Karagiannis TC. Histone deacetylase inhibitors: Can we consider potent antineoplastic agents for the treatment of asthma? Ann Clin Lab Sci 2012; 42:338-345
-
(2012)
Ann Clin Lab Sci
, vol.42
, pp. 338-345
-
-
Royce, S.G.1
Ververis, K.2
Karagiannis, T.C.3
-
5
-
-
84876124887
-
Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases
-
Sundar IK, Yao H, Rahman I. Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. Antioxid Redox Signal 2013; 18:1956-1971
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1956-1971
-
-
Sundar, I.K.1
Yao, H.2
Rahman, I.3
-
6
-
-
84876672758
-
Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-delta
-
Do-Umehara HC, Chen C, Urich D, et al. Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-delta. Nat Immunol 2013; 14:461-469
-
(2013)
Nat Immunol
, vol.14
, pp. 461-469
-
-
Do-Umehara, H.C.1
Chen, C.2
Urich, D.3
-
7
-
-
84875344085
-
Development and regeneration of Sox2endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway
-
Wang Y, Tian Y, Morley MP, et al. Development and regeneration of Sox2endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. Dev Cell 2013; 24:345-358
-
(2013)
Dev Cell
, vol.24
, pp. 345-358
-
-
Wang, Y.1
Tian, Y.2
Morley, M.P.3
-
8
-
-
84877949634
-
Development of new drugs for COPD
-
Barnes PJ. Development of new drugs for COPD. Curr Med Chem 2013; 20:1531-1540
-
(2013)
Curr Med Chem
, vol.20
, pp. 1531-1540
-
-
Barnes, P.J.1
-
9
-
-
84875225940
-
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
-
Barnes PJ. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J Allergy Clin Immunol 2013; 131:636-645
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 636-645
-
-
Barnes, P.J.1
-
10
-
-
84863224541
-
Corticosteroid resistance and novel antiinflammatory therapies in chronic obstructive pulmonary disease: Current evidence and future direction
-
Hakim A, Adcock IM, Usmani OS. Corticosteroid resistance and novel antiinflammatory therapies in chronic obstructive pulmonary disease: Current evidence and future direction. Drugs 2012; 72:1299-1312
-
(2012)
Drugs
, vol.72
, pp. 1299-1312
-
-
Hakim, A.1
Adcock, I.M.2
Usmani, O.S.3
-
11
-
-
84859846425
-
Glucocorticoid receptor beta and histone deacetylase 1 and 2 expression in the airways of severe asthma
-
Butler CA, McQuaid S, Taggart CC, et al. Glucocorticoid receptor beta and histone deacetylase 1 and 2 expression in the airways of severe asthma. Thorax 2012; 67:392-398
-
(2012)
Thorax
, vol.67
, pp. 392-398
-
-
Butler, C.A.1
McQuaid, S.2
Taggart, C.C.3
-
12
-
-
84881002949
-
Characteristics of histone deacetylase 9 in peripheral blood of patients with bronchial asthma
-
Hou XX, Shi GC, Wan HY, et al. Characteristics of histone deacetylase 9 in peripheral blood of patients with bronchial asthma. Zhonghua Jie He He Hu Xi Za Zhi 2012; 35:340-344
-
(2012)
Zhonghua Jie He He Hu Xi Za Zhi
, vol.35
, pp. 340-344
-
-
Hou, X.X.1
Shi, G.C.2
Wan, H.Y.3
-
13
-
-
84870610363
-
Phosphodiesterase-4 inhibition improves corticosteroid insensitivity in pulmonary endothelial cells under oxidative stress
-
Ortiz JL, Milara J, Lluch J, et al. Phosphodiesterase-4 inhibition improves corticosteroid insensitivity in pulmonary endothelial cells under oxidative stress. Allergy 2013; 68:64-73
-
(2013)
Allergy
, vol.68
, pp. 64-73
-
-
Ortiz, J.L.1
Milara, J.2
Lluch, J.3
-
14
-
-
84877724839
-
Expression level of histone deacetylase 2 correlates with occurring of chronic obstructive pulmonary diseases
-
Qu Y, Yang Y, Ma D, et al. Expression level of histone deacetylase 2 correlates with occurring of chronic obstructive pulmonary diseases. Mol Biol Rep 2013; 40:3995-4000
-
(2013)
Mol Biol Rep
, vol.40
, pp. 3995-4000
-
-
Qu, Y.1
Yang, Y.2
Ma, D.3
-
15
-
-
84864041122
-
Smoke exposure of human macrophages reduces HDAC3 activity, resulting in enhanced inflammatory cytokine production
-
Winkler AR, Nocka KN, Williams CM. Smoke exposure of human macrophages reduces HDAC3 activity, resulting in enhanced inflammatory cytokine production. Pulm Pharmacol Ther 2012; 25:286-292
-
(2012)
Pulm Pharmacol Ther
, vol.25
, pp. 286-292
-
-
Winkler, A.R.1
Nocka, K.N.2
Williams, C.M.3
-
16
-
-
84865988601
-
Characteristic comparison of three rat models induced by cigarette smoke or combined with LPS: To establish a suitable model for study of airway mucus hypersecretion in chronic obstructive pulmonary disease
-
Nie YC, Wu H, Li PB, et al. Characteristic comparison of three rat models induced by cigarette smoke or combined with LPS: To establish a suitable model for study of airway mucus hypersecretion in chronic obstructive pulmonary disease. Pulm Pharmacol Ther 2012; 25:349-356
-
(2012)
Pulm Pharmacol Ther
, vol.25
, pp. 349-356
-
-
Nie, Y.C.1
Wu, H.2
Li, P.B.3
-
17
-
-
84879379272
-
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts
-
Huang SK, Scruggs AM, Donaghy J, et al. Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts. Cell Death Dis 2013; 4:e621
-
(2013)
Cell Death Dis
, vol.4
-
-
Huang, S.K.1
Scruggs, A.M.2
Donaghy, J.3
-
18
-
-
84892364115
-
Aberrant expression and activity of histone deacetylases (hdacs in lungs of patients with sporadic idiopathic pulmonary fibrosis (ipf
-
Korfei M, Buchwald M, Klepetko W, et al. Aberrant expression and activity of histone deacetylases (HDACs) in lungs of patients with sporadic Idiopathic Pulmonary Fibrosis (IPF). Pneumologie 2012; 66:A506
-
(2012)
Pneumologie
, vol.66
-
-
Korfei, M.1
Buchwald, M.2
Klepetko, W.3
-
19
-
-
84869761100
-
Histone deacetylase (HDAC) 1 controls the expression of beta defensin 1 in human lung epithelial cells
-
Kallsen K, Andresen E, Heine H. Histone deacetylase (HDAC) 1 controls the expression of beta defensin 1 in human lung epithelial cells. PloS ONE 2012; 7:e50000
-
(2012)
PloS ONE
, vol.7
-
-
Kallsen, K.1
Andresen, E.2
Heine, H.3
-
20
-
-
84875949671
-
Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells
-
Liu Q, Liu J, Roschmann KI, et al. Histone deacetylase inhibitors up-regulate LL-37 expression independent of toll-like receptor mediated signalling in airway epithelial cells. J Inflamm (Lond) 2013; 10:15
-
(2013)
J Inflamm (Lond
, vol.10
, pp. 15
-
-
Liu, Q.1
Liu, J.2
Roschmann, K.I.3
-
21
-
-
84862613471
-
Experimental therapeutics of Nrf2 as a target for prevention of bacterial exacerbations in COPD
-
Biswal S, Thimmulappa RK, Harvey CJ. Experimental therapeutics of Nrf2 as a target for prevention of bacterial exacerbations in COPD. Proc Am Thorac Soc 2012; 9:47-51
-
(2012)
Proc Am Thorac Soc
, vol.9
, pp. 47-51
-
-
Biswal, S.1
Thimmulappa, R.K.2
Harvey, C.J.3
-
22
-
-
84868308186
-
Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression
-
Chen Y, Watson AM, Williamson CD, et al. Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression. Am J Respir Cell Mol Biol 2012; 47:637-644
-
(2012)
Am J Respir Cell Mol Biol
, vol.47
, pp. 637-644
-
-
Chen, Y.1
Watson, A.M.2
Williamson, C.D.3
-
23
-
-
84864290214
-
Histone deacetylation inhibition in pulmonary hypertension: Therapeutic potential of valproic acid and suberoylanilide hydroxamic acid
-
Zhao L, Chen CN, Hajji N, et al. Histone deacetylation inhibition in pulmonary hypertension: Therapeutic potential of valproic acid and suberoylanilide hydroxamic acid. Circulation 2012; 126:455-467
-
(2012)
Circulation
, vol.126
, pp. 455-467
-
-
Zhao, L.1
Chen, C.N.2
Hajji, N.3
-
24
-
-
84876888400
-
Sodium butyrate inhibits plateletderived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition
-
Cantoni S, Galletti M, Zambelli F, et al. Sodium butyrate inhibits plateletderived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition. FEBS J 2013; 280:2042-2055
-
(2013)
FEBS J
, vol.280
, pp. 2042-2055
-
-
Cantoni, S.1
Galletti, M.2
Zambelli, F.3
-
25
-
-
84867194829
-
Histone deacetylases inhibitor Trichostatin A ameliorates DNFB-induced allergic contact dermatitis and reduces epidermal Langerhans cells in mice
-
Shi YL, Gu J, Park JY, et al. Histone deacetylases inhibitor Trichostatin A ameliorates DNFB-induced allergic contact dermatitis and reduces epidermal Langerhans cells in mice. J Dermatol Sci 2012; 68:99-107
-
(2012)
J Dermatol Sci
, vol.68
, pp. 99-107
-
-
Shi, Y.L.1
Gu, J.2
Park, J.Y.3
-
26
-
-
84864389647
-
Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein
-
Kim Y, Kim K, Park D, et al. Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein. J Biol Chem 2012; 287:25844-25859
-
(2012)
J Biol Chem
, vol.287
, pp. 25844-25859
-
-
Kim, Y.1
Kim, K.2
Park, D.3
-
27
-
-
84878574917
-
Inhibition of human B-cell development into plasmablasts by histone deacetylase inhibitor valproic acid
-
1699
-
Kienzler AK, Rizzi M, Reith M, et al. Inhibition of human B-cell development into plasmablasts by histone deacetylase inhibitor valproic acid. J Allergy Clin Immunol 2013; 131:1695-1699; e1699
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 1695-1699
-
-
Kienzler, A.K.1
Rizzi, M.2
Reith, M.3
-
28
-
-
84856634405
-
Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models
-
Banerjee A, Trivedi CM, Damera G, et al. Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models. Am J Respir Cell Mol Biol 2012; 46:132-138
-
(2012)
Am J Respir Cell Mol Biol
, vol.46
, pp. 132-138
-
-
Banerjee, A.1
Trivedi, C.M.2
Damera, G.3
-
29
-
-
84868334619
-
Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of alpha1-antitrypsin deficiency
-
Bouchecareilh M, Hutt DM, Szajner P, et al. Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of alpha1-antitrypsin deficiency. J Biol Chem 2012; 287:38265-38278
-
(2012)
J Biol Chem
, vol.287
, pp. 38265-38278
-
-
Bouchecareilh, M.1
Hutt, D.M.2
Szajner, P.3
-
30
-
-
84870915628
-
Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude longterm hypoxia: Role of histone acetylation
-
Yang Q, Lu Z, Ramchandran R, et al. Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude longterm hypoxia: Role of histone acetylation. Am J Physiol Lung Cell Mol Physiol 2012; 303:L1001-L1010
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Yang, Q.1
Lu, Z.2
Ramchandran, R.3
-
31
-
-
84866505345
-
Effects of the histone deacetylase inhibitor, trichostatin A, in a chronic allergic airways disease model in mice
-
Royce SG, Dang W, Yuan G, et al. Effects of the histone deacetylase inhibitor, trichostatin A, in a chronic allergic airways disease model in mice. Arch Immunol Ther Exp 2012; 60:295-306
-
(2012)
Arch Immunol Ther Exp
, vol.60
, pp. 295-306
-
-
Royce, S.G.1
Dang, W.2
Yuan, G.3
-
32
-
-
84860529331
-
Spiruchostatin A inhibits proliferation and differentiation of fibroblasts from patients with pulmonary fibrosis
-
Davies ER, Haitchi HM, Thatcher TH, et al. Spiruchostatin A inhibits proliferation and differentiation of fibroblasts from patients with pulmonary fibrosis. Am J Respir Cell Mol Biol 2012; 46:687-694
-
(2012)
Am J Respir Cell Mol Biol
, vol.46
, pp. 687-694
-
-
Davies, E.R.1
Haitchi, H.M.2
Thatcher, T.H.3
-
34
-
-
84867861519
-
Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
-
Yao H, Rahman I. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. Biochem Pharmacol 2012; 84:1332-1339
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 1332-1339
-
-
Yao, H.1
Rahman, I.2
-
35
-
-
84863898701
-
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice
-
Xu B, Chen H, Xu W, et al. Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. Am J Physiol Lung Cell Mol Physiol 2012; 303:L89-L96
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Xu, B.1
Chen, H.2
Xu, W.3
-
36
-
-
84861831957
-
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice
-
Yao H, Chung S, Hwang JW, et al. SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. J Clin Invest 2012; 122:2032-2045
-
(2012)
J Clin Invest
, vol.122
, pp. 2032-2045
-
-
Yao, H.1
Chung, S.2
Hwang, J.W.3
-
37
-
-
84858020464
-
Sirt1 protects against thrombomodulin downregulation and lung coagulation after particulate matter exposure
-
Wu Z, Liu MC, Liang M, Fu J. Sirt1 protects against thrombomodulin downregulation and lung coagulation after particulate matter exposure. Blood 2012; 119:2422-2429
-
(2012)
Blood
, vol.119
, pp. 2422-2429
-
-
Wu, Z.1
Liu, M.C.2
Liang, M.3
Fu, J.4
-
38
-
-
84875491560
-
Different patterns of lung sirtuin expression in smokers with and without chronic obstructive pulmonary disease
-
Isajevs S, Strazda G, Kopeika U, Taivans I. Different patterns of lung sirtuin expression in smokers with and without chronic obstructive pulmonary disease. Medicina (Kaunas) 2012; 48:552-557
-
(2012)
Medicina (Kaunas
, vol.48
, pp. 552-557
-
-
Isajevs, S.1
Strazda, G.2
Kopeika, U.3
Taivans, I.4
-
39
-
-
84872407198
-
TGF-beta-Smad3 signaling in emphysema and pulmonary fibrosis an epigenetic aberration of normal development?
-
Warburton D, Shi W, Xu B. TGF-beta-Smad3 signaling in emphysema and pulmonary fibrosis: An epigenetic aberration of normal development? Am J Physiol Lung Cell Mol Physiol 2013; 304:L83-L85
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
-
-
Warburton, D.1
Shi, W.2
Xu, B.3
-
40
-
-
84872932620
-
Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma
-
Ichikawa T, Hayashi R, Suzuki K, et al. Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma. Respirology 2013; 18:332-339
-
(2013)
Respirology
, vol.18
, pp. 332-339
-
-
Ichikawa, T.1
Hayashi, R.2
Suzuki, K.3
-
41
-
-
84867818312
-
Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury
-
Rieder SA, Nagarkatti P, Nagarkatti M. Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury. Br J Pharmacol 2012; 167:1244-1258
-
(2012)
Br J Pharmacol
, vol.167
, pp. 1244-1258
-
-
Rieder, S.A.1
Nagarkatti, P.2
Nagarkatti, M.3
-
42
-
-
84896804761
-
Resveratrol has protective effects against airway remodeling and airway inflammation in a murine model of allergic airways disease
-
Royce SG, Dang W, Gao Y, et al. Resveratrol has protective effects against airway remodeling and airway inflammation in a murine model of allergic airways disease. Pathobiol Aging Age Relat Dis 2011; 1:7134
-
(2011)
Pathobiol Aging Age Relat Dis
, vol.1
, pp. 7134
-
-
Royce, S.G.1
Dang, W.2
Gao, Y.3
|