Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Ryan, Dorothy M ^a   Vincent, Thomas L ^a   Salit, Jacqueline ^a   Walters, Matthew S ^a   Agosto Perez, Francisco ^b   Shaykhiev, Renat ^a   Strulovici Barel, Yael ^a   Downey, Robert J ^c   Buro Auriemma, Lauren J ^a   Staudt, Michelle R ^a   Hackett, Neil R ^a   Mezey, Jason G ^a,b   Crystal, Ronald G ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Plant Breeding and Genetics Section in the School of Integrative Plant Science   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BASAL CELL; CHROMOSOME 19; CHRONIC OBSTRUCTIVE LUNG DISEASE; COPY NUMBER VARIATION; DISEASE ASSOCIATION; EGLN2 GENE; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HYPERPLASIA; LTBP4 GENE; NFKBIB GENE; RESPIRATORY EPITHELIUM; RNA SEQUENCE; SMOKING; SQUAMOUS CELL METAPLASIA; STEM CELL; TGFB1 GENE; UPREGULATION;

ADULT; BIOLOGICAL MARKERS; CHROMOSOMES, HUMAN, PAIR 19; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SMOKING;

EID: 84894618119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088051     Document Type: Article

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