-
1
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini, L., Martinon, F., Burns, K., McDermott, M.F., Hawkins, P.N., Tschopp, J., NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20 (2004), 319–325.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
2
-
-
84924706729
-
Epithelial NAIPs protect against colonic tumorigenesis
-
Allam, R., Maillard, M.H., Tardivel, A., Chennupati, V., Bega, H., Yu, C.W., Velin, D., Schneider, P., Maslowski, K.M., Epithelial NAIPs protect against colonic tumorigenesis. J. Exp. Med. 212 (2015), 369–383.
-
(2015)
J. Exp. Med.
, vol.212
, pp. 369-383
-
-
Allam, R.1
Maillard, M.H.2
Tardivel, A.3
Chennupati, V.4
Bega, H.5
Yu, C.W.6
Velin, D.7
Schneider, P.8
Maslowski, K.M.9
-
3
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
Allen, I., TeKippe, E.M., Woodford, R.M., Uronis, J.M., Holl, E.K., Rogers, A.B., Herfarth, H.H., Jobin, C., Ting, J.P., The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J. Exp. Med. 207 (2010), 1045–1056.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1045-1056
-
-
Allen, I.1
TeKippe, E.M.2
Woodford, R.M.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
Herfarth, H.H.7
Jobin, C.8
Ting, J.P.9
-
4
-
-
57249094341
-
Initial description of the human NLRP3 promoter
-
Anderson, J.P., Mueller, J.L., Misaghi, A., Anderson, S., Sivagnanam, M., Kolodner, R.D., Hoffman, H.M., Initial description of the human NLRP3 promoter. Genes Immun. 9 (2008), 721–726.
-
(2008)
Genes Immun.
, vol.9
, pp. 721-726
-
-
Anderson, J.P.1
Mueller, J.L.2
Misaghi, A.3
Anderson, S.4
Sivagnanam, M.5
Kolodner, R.D.6
Hoffman, H.M.7
-
5
-
-
77956128040
-
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
-
Bauer, C., Duewell, P., Mayer, C., Lehr, H.A., Fitzgerald, K.A., Dauer, M., Tschopp, J., Endres, S., Latz, E., Schnurr, M., Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut 59 (2010), 1192–1199.
-
(2010)
Gut
, vol.59
, pp. 1192-1199
-
-
Bauer, C.1
Duewell, P.2
Mayer, C.3
Lehr, H.A.4
Fitzgerald, K.A.5
Dauer, M.6
Tschopp, J.7
Endres, S.8
Latz, E.9
Schnurr, M.10
-
6
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind, F.G., Horvath, G., Stutz, A., Alnemri, E.S., MacDonald, K., Speert, D., Fernandes-Alnemri, T., Wu, J., Monks, B.G., Fitzgerald, K.A., Hornung, V., Latz, E., Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J. Immunol. 183 (2009), 787–791.
-
(2009)
J. Immunol.
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
7
-
-
84867304098
-
NLRP3 inflammasome activity is negatively controlled by miR-223
-
Bauernfeind, F., Rieger, A., Schildberg, F.A., Knolle, P.A., Schmid-Burgk, J.L., Hornung, V., NLRP3 inflammasome activity is negatively controlled by miR-223. J. Immunol. 189 (2012), 4175–4181.
-
(2012)
J. Immunol.
, vol.189
, pp. 4175-4181
-
-
Bauernfeind, F.1
Rieger, A.2
Schildberg, F.A.3
Knolle, P.A.4
Schmid-Burgk, J.L.5
Hornung, V.6
-
8
-
-
84921909014
-
The inflammasomes and autoinflammatory syndromes
-
Broderick, L., De Nardo, D., Franklin, B.S., Hoffman, H.M., Latz, E., The inflammasomes and autoinflammatory syndromes. Annu. Rev. Pathol. 10 (2015), 395–424.
-
(2015)
Annu. Rev. Pathol.
, vol.10
, pp. 395-424
-
-
Broderick, L.1
De Nardo, D.2
Franklin, B.S.3
Hoffman, H.M.4
Latz, E.5
-
9
-
-
84872086179
-
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
-
Bruchard, M., Mignot, G., Derangère, V., Chalmin, F., Chevriaux, A., Végran, F., Boireau, W., Simon, B., Ryffel, B., Connat, J.L., Kanellopoulos, J., Martin, F., Rébé, C., Apetoh, L., Ghiringhelli, F., Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat. Med. 19 (2013), 57–64.
-
(2013)
Nat. Med.
, vol.19
, pp. 57-64
-
-
Bruchard, M.1
Mignot, G.2
Derangère, V.3
Chalmin, F.4
Chevriaux, A.5
Végran, F.6
Boireau, W.7
Simon, B.8
Ryffel, B.9
Connat, J.L.10
Kanellopoulos, J.11
Martin, F.12
Rébé, C.13
Apetoh, L.14
Ghiringhelli, F.15
-
10
-
-
66949115474
-
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity
-
Brydges, S.D., Mueller, J., McGeough, M.D., Pena, C.A., Misaghi, A., Gandhi, C., Putnam, C.D., Boyle, D.L., Firestein, G.S., Horner, A.A., Soroosh, P., Watford, W.T., O'Shea, J.J., Kastner, D.L., Hoffman, H.M., Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity. Immunity 30 (2009), 875–887.
-
(2009)
Immunity
, vol.30
, pp. 875-887
-
-
Brydges, S.D.1
Mueller, J.2
McGeough, M.D.3
Pena, C.A.4
Misaghi, A.5
Gandhi, C.6
Putnam, C.D.7
Boyle, D.L.8
Firestein, G.S.9
Horner, A.A.10
Soroosh, P.11
Watford, W.T.12
O'Shea, J.J.13
Kastner, D.L.14
Hoffman, H.M.15
-
11
-
-
84983132688
-
Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies
-
Cavalli, G., Dinarello, C.A., Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies. Rheumatology (Oxford) 54 (2015), 2134–2144.
-
(2015)
Rheumatology (Oxford)
, vol.54
, pp. 2134-2144
-
-
Cavalli, G.1
Dinarello, C.A.2
-
12
-
-
0034658465
-
The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators
-
Centola, M., Wood, G., Frucht, D.M., Galon, J., Aringer, M., Farrell, C., Kingma, D.W., Horwitz, M.E., Mansfield, E., Holland, S.M., O'Shea, J.J., Rosenberg, H.F., Malech, H.L., Kastner, D.L., The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators. Blood 95 (2000), 3223–3231.
-
(2000)
Blood
, vol.95
, pp. 3223-3231
-
-
Centola, M.1
Wood, G.2
Frucht, D.M.3
Galon, J.4
Aringer, M.5
Farrell, C.6
Kingma, D.W.7
Horwitz, M.E.8
Mansfield, E.9
Holland, S.M.10
O'Shea, J.J.11
Rosenberg, H.F.12
Malech, H.L.13
Kastner, D.L.14
-
13
-
-
79959540809
-
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
-
Chen, G.Y., Liu, M., Wang, F., Bertin, J., Núñez, G., A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J. Immunol. 186 (2011), 7187–7194.
-
(2011)
J. Immunol.
, vol.186
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Núñez, G.5
-
14
-
-
84869206979
-
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases
-
Chow, M.T., Sceneay, J., Paget, C., Wong, C.S., Duret, H., Tschopp, J., Möller, A., Smyth, M.J., NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases. Cancer Res. 72 (2012), 5721–5732.
-
(2012)
Cancer Res.
, vol.72
, pp. 5721-5732
-
-
Chow, M.T.1
Sceneay, J.2
Paget, C.3
Wong, C.S.4
Duret, H.5
Tschopp, J.6
Möller, A.7
Smyth, M.J.8
-
15
-
-
84885077685
-
TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation
-
Chuang, S.Y., Yang, C.H., Chou, C.C., Chiang, Y.P., Chuang, T.H., Hsu, L.C., TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 16079–16084.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 16079-16084
-
-
Chuang, S.Y.1
Yang, C.H.2
Chou, C.C.3
Chiang, Y.P.4
Chuang, T.H.5
Hsu, L.C.6
-
16
-
-
84924415042
-
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
-
Coll, R.C., Robertson, A.A., Chae, J.J., Higgins, S.C., Muñoz-Planillo, R., Inserra, M.C., Vetter, I., Dungan, L.S., Monks, B.G., Stutz, A., Croker, D.E., Butler, M.S., Haneklaus, M., Sutton, C.E., Núñez, G., Latz, E., Kastner, D.L., Mills, K.H., Masters, S.L., Schroder, K., Cooper, M.A., O'Neill, L.A., A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat. Med. 21 (2015), 248–255.
-
(2015)
Nat. Med.
, vol.21
, pp. 248-255
-
-
Coll, R.C.1
Robertson, A.A.2
Chae, J.J.3
Higgins, S.C.4
Muñoz-Planillo, R.5
Inserra, M.C.6
Vetter, I.7
Dungan, L.S.8
Monks, B.G.9
Stutz, A.10
Croker, D.E.11
Butler, M.S.12
Haneklaus, M.13
Sutton, C.E.14
Núñez, G.15
Latz, E.16
Kastner, D.L.17
Mills, K.H.18
Masters, S.L.19
Schroder, K.20
Cooper, M.A.21
O'Neill, L.A.22
more..
-
17
-
-
84939152599
-
Transcription factor ATF4 induces NLRP1 inflammasome expression during endoplasmic reticulum stress
-
D'Osualdo, A., Anania, V.G., Yu, K., Lill, J.R., Kaufman, R.J., Matsuzawa, S., Reed, J.C., Transcription factor ATF4 induces NLRP1 inflammasome expression during endoplasmic reticulum stress. PLoS One, 10, 2015, e0130635.
-
(2015)
PLoS One
, vol.10
, pp. e0130635
-
-
D'Osualdo, A.1
Anania, V.G.2
Yu, K.3
Lill, J.R.4
Kaufman, R.J.5
Matsuzawa, S.6
Reed, J.C.7
-
18
-
-
84868529740
-
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis
-
Drexler, S.K., Bonsignore, L., Masin, M., Tardivel, A., Jackstadt, R., Hermeking, H., Schneider, P., Gross, O., Tschopp, J., Yazdi, A.S., Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 18384–18389.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 18384-18389
-
-
Drexler, S.K.1
Bonsignore, L.2
Masin, M.3
Tardivel, A.4
Jackstadt, R.5
Hermeking, H.6
Schneider, P.7
Gross, O.8
Tschopp, J.9
Yazdi, A.S.10
-
19
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewel, L., Kono, H., Rayner, K.J., Sirois, C.M., Vladimer, G., Bauernfeind, F.G., Abela, G.S., Franchi, L., Nuñez, G., Schnurr, M., Espevik, T., Lien, E., Fitzgerald, K.A., Rock, K.L., Moore, K.J., Wright, S.D., Hornung, V., Latz, E., NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nat. Med. 464 (2010), 1357–1361.
-
(2010)
Nat. Med.
, vol.464
, pp. 1357-1361
-
-
Duewel, L.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nuñez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
20
-
-
84919421199
-
Genetic variations of NLRP1: susceptibility in psoriasis
-
Ekman, A.K., Verma, D., Fredrikson, M., Bivik, C., Enerbäck, C., Genetic variations of NLRP1: susceptibility in psoriasis. Br. J. Dermatol. 171 (2014), 1517–1520.
-
(2014)
Br. J. Dermatol.
, vol.171
, pp. 1517-1520
-
-
Ekman, A.K.1
Verma, D.2
Fredrikson, M.3
Bivik, C.4
Enerbäck, C.5
-
21
-
-
84904692363
-
The adaptor ASC has extracellular and ‘prionoid’ activities that propagate inflammation
-
Franklin, B.S., Bossaller, L., De Nardo, D., Ratter, J.M., Stutz, A., Engels, G., Brenker, C., Nordhoff, M., Mirandola, S.R., Al-Amoudi, A., Mangan, M.S., Zimmer, S., Monks, B.G., Fricke, M., Schmidt, R.E., Espevik, T., Jones, B., Jarnicki, A.G., Hansbro, P.M., Busto, P., Marshak-Rothstein, A., Hornemann, S., Aguzzi, A., Kastenmüller, W., Latz, E., The adaptor ASC has extracellular and ‘prionoid’ activities that propagate inflammation. Nat. Immunol. 15 (2014), 727–737.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
Ratter, J.M.4
Stutz, A.5
Engels, G.6
Brenker, C.7
Nordhoff, M.8
Mirandola, S.R.9
Al-Amoudi, A.10
Mangan, M.S.11
Zimmer, S.12
Monks, B.G.13
Fricke, M.14
Schmidt, R.E.15
Espevik, T.16
Jones, B.17
Jarnicki, A.G.18
Hansbro, P.M.19
Busto, P.20
Marshak-Rothstein, A.21
Hornemann, S.22
Aguzzi, A.23
Kastenmüller, W.24
Latz, E.25
more..
-
22
-
-
84956596401
-
The pathogenic role of the inflammasome in neurodegenerative diseases
-
Freeman, L.C., Ting, J.P., The pathogenic role of the inflammasome in neurodegenerative diseases. J. Neurochem. 136 (2016), 29–38.
-
(2016)
J. Neurochem.
, vol.136
, pp. 29-38
-
-
Freeman, L.C.1
Ting, J.P.2
-
23
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli, F., Apetoh, L., Tesniere, A., Aymeric, L., Ma, Y., Ortiz, C., Vermaelen, K., Panaretakis, T., Mignot, G., Ullrich, E., Perfettini, J.L., Schlemmer, F., Tasdemir, E., Uhl, M., Génin, P., Civas, A., Ryffel, B., Kanellopoulos, J., Tschopp, J., André, F., Lidereau, R., McLaughlin, N.M., Haynes, N.M., Smyth, M.J., Kroemer, G., Zitvogel, L., Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med. 15 (2009), 1170–1178.
-
(2009)
Nat. Med.
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
Vermaelen, K.7
Panaretakis, T.8
Mignot, G.9
Ullrich, E.10
Perfettini, J.L.11
Schlemmer, F.12
Tasdemir, E.13
Uhl, M.14
Génin, P.15
Civas, A.16
Ryffel, B.17
Kanellopoulos, J.18
Tschopp, J.19
André, F.20
Lidereau, R.21
McLaughlin, N.M.22
Haynes, N.M.23
Smyth, M.J.24
Kroemer, G.25
Zitvogel, L.26
more..
-
25
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
-
Gringhuis, S.I., Kaptein, T., Wevers, B.A., Theelen, B., van der Vlist, M., Boekhout, T., Geijtenbeek, T.B., Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome. Nat. Immunol. 13 (2012), 246–254.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.2
Wevers, B.A.3
Theelen, B.4
van der Vlist, M.5
Boekhout, T.6
Geijtenbeek, T.B.7
-
26
-
-
77955475968
-
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
-
Gris, D., Ye, Z., Iocca, H.A., Wen, H., Craven, R.R., Gris, P., Huang, M., Schneider, M., Miller, S.D., Ting, J.P., NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J. Immunol. 185 (2010), 974–981.
-
(2010)
J. Immunol.
, vol.185
, pp. 974-981
-
-
Gris, D.1
Ye, Z.2
Iocca, H.A.3
Wen, H.4
Craven, R.R.5
Gris, P.6
Huang, M.7
Schneider, M.8
Miller, S.D.9
Ting, J.P.10
-
27
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
-
Halle, A., Hornung, V., Petzold, G.C., Stewart, C.R., Monks, B.G., Reinheckel, T., Fitzgerald, K.A., Latz, E., Moore, K.J., Golenbock, D.T., The NALP3 inflammasome is involved in the innate immune response to amyloid-β. Nat. Immunol. 9 (2008), 857–865.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
28
-
-
84894196760
-
Inflammasomes and metabolic disease
-
Henao-Mejia, J., Elinav, E., Thaiss, C.A., Flavell, R.A., Inflammasomes and metabolic disease. Annu. Rev. Physiol. 76 (2014), 57–78.
-
(2014)
Annu. Rev. Physiol.
, vol.76
, pp. 57-78
-
-
Henao-Mejia, J.1
Elinav, E.2
Thaiss, C.A.3
Flavell, R.A.4
-
29
-
-
84873087532
-
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
-
Heneka, M.T., Kummer, V.P., Stutz, A., Delekate, A., Schwartz, S., Vieira-Saecker, A., Griep, A., Axt, D., Remus, A., Tzeng, T.C., Gelpi, E., Halle, A., Korte, M., Latz, E., Golenbock, D.T., NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nat. Med. 493 (2013), 674–678.
-
(2013)
Nat. Med.
, vol.493
, pp. 674-678
-
-
Heneka, M.T.1
Kummer, V.P.2
Stutz, A.3
Delekate, A.4
Schwartz, S.5
Vieira-Saecker, A.6
Griep, A.7
Axt, D.8
Remus, A.9
Tzeng, T.C.10
Gelpi, E.11
Halle, A.12
Korte, M.13
Latz, E.14
Golenbock, D.T.15
-
30
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman, H.M., Mueller, J.L., Broide, D.H., Wanderer, A.A., Kolodner, R.D., Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29 (2001), 301–305.
-
(2001)
Nat. Genet.
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
31
-
-
80052175401
-
Intracellular sensing of microbes and danger signals by the inflammasomes
-
Horvath, G.L., Schrum, J.E., De Nardo, C.M., Latz, E., Intracellular sensing of microbes and danger signals by the inflammasomes. Immunol. Rev. 243 (2011), 119–135.
-
(2011)
Immunol. Rev.
, vol.243
, pp. 119-135
-
-
Horvath, G.L.1
Schrum, J.E.2
De Nardo, C.M.3
Latz, E.4
-
32
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
Hu, B., Elinav, E., Huber, S., Booth, C.J., Strowig, T., Jin, C., Eisenbarth, S.C., Flavell, R.A., Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 21635–21640.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Booth, C.J.4
Strowig, T.5
Jin, C.6
Eisenbarth, S.C.7
Flavell, R.A.8
-
33
-
-
84907312816
-
Aryl hydrocarbon receptor negatively regulates NLRP3 inflammasome activity by inhibiting NLRP3 transcription
-
Huai, W., Zhao, R., Song, H., Zhao, J., Zhang, L., Zhang, L., Gao, C., Han, L., Zhao, W., Aryl hydrocarbon receptor negatively regulates NLRP3 inflammasome activity by inhibiting NLRP3 transcription. Nat. Commun., 5, 2014, 4738.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4738
-
-
Huai, W.1
Zhao, R.2
Song, H.3
Zhao, J.4
Zhang, L.5
Zhang, L.6
Gao, C.7
Han, L.8
Zhao, W.9
-
34
-
-
84905961531
-
The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis?
-
Kahlenberg, J.M., Kaplan, M.J., The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis?. Curr. Opin. Rheumatol. 26 (2014), 475–481.
-
(2014)
Curr. Opin. Rheumatol.
, vol.26
, pp. 475-481
-
-
Kahlenberg, J.M.1
Kaplan, M.J.2
-
35
-
-
79951679204
-
Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
-
Kawaguchi, M., Takahashi, M., Hata, T., Kashima, Y., Usui, F., Morimoto, H., Izawa, A., Takahashi, Y., Masumoto, J., Koyama, J., Hongo, M., Noda, T., Nakayama, J., Sagara, J., Taniguchi, S., Ikeda, U., Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 123 (2011), 594–604.
-
(2011)
Circulation
, vol.123
, pp. 594-604
-
-
Kawaguchi, M.1
Takahashi, M.2
Hata, T.3
Kashima, Y.4
Usui, F.5
Morimoto, H.6
Izawa, A.7
Takahashi, Y.8
Masumoto, J.9
Koyama, J.10
Hongo, M.11
Noda, T.12
Nakayama, J.13
Sagara, J.14
Taniguchi, S.15
Ikeda, U.16
-
36
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
Kawai, T., Akira, S., The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11 (2010), 373–384.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
37
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki, N., Warming, S., Lamkanfi, M., Vande Walle, L., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., Zhang, J., Lee, W.P., Roose-Girma, M., Dixit, V.M., Non-canonical inflammasome activation targets caspase-11. Nature 479 (2011), 117–121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
Zhang, J.11
Lee, W.P.12
Roose-Girma, M.13
Dixit, V.M.14
-
38
-
-
82955249021
-
NOD-like receptors and the innate immune system: coping with danger: damage and death
-
Kersse, K., Bertrand, M., Lamkanfi, M., Vandenabeele, P., NOD-like receptors and the innate immune system: coping with danger: damage and death. Cytokine Growth Factor Rev. 22 (2011), 257–276.
-
(2011)
Cytokine Growth Factor Rev.
, vol.22
, pp. 257-276
-
-
Kersse, K.1
Bertrand, M.2
Lamkanfi, M.3
Vandenabeele, P.4
-
39
-
-
84878246239
-
Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens
-
Kuemmerle-Deschner, J.B., Wittkowski, H., Tyrrell, P.N., Koetter, I., Lohse, P., Ummenhofer, K., Reess, F., Hansmann, S., Koitschev, A., Deuter, C., Bialkowski, A., Foell, D., Benseler, S.M., Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens. Arthritis Res. Ther., 15, 2013, R64.
-
(2013)
Arthritis Res. Ther.
, vol.15
, pp. R64
-
-
Kuemmerle-Deschner, J.B.1
Wittkowski, H.2
Tyrrell, P.N.3
Koetter, I.4
Lohse, P.5
Ummenhofer, K.6
Reess, F.7
Hansmann, S.8
Koitschev, A.9
Deuter, C.10
Bialkowski, A.11
Foell, D.12
Benseler, S.M.13
-
40
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
Latz, E., Xiao, T.S., Stutz, A., Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13 (2013), 397–411.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
41
-
-
84902551656
-
NLRC5 mediates cytokine secretion in RAW264.7 macrophages and modulated by the JAK2/STAT3 pathway
-
Epub ahead of print
-
Li, L., Xu, T., Huang, C., Peng, Y., Li, J., NLRC5 mediates cytokine secretion in RAW264.7 macrophages and modulated by the JAK2/STAT3 pathway. Inflammation, 2014 Epub ahead of print.
-
(2014)
Inflammation
-
-
Li, L.1
Xu, T.2
Huang, C.3
Peng, Y.4
Li, J.5
-
42
-
-
84963753938
-
Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury
-
Lin, W.P., Xiong, G., Lin, Q., Chen, X.W., Zhang, L.Q., Shi, J.X., Ke, Q.F., Lin, J.H., Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury. J. Neuroinflammation, 13, 2016, 52.
-
(2016)
J. Neuroinflammation
, vol.13
, pp. 52
-
-
Lin, W.P.1
Xiong, G.2
Lin, Q.3
Chen, X.W.4
Zhang, L.Q.5
Shi, J.X.6
Ke, Q.F.7
Lin, J.H.8
-
43
-
-
84872607356
-
Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma
-
Liu, W., Luo, Y., Dunn, J.H., Norris, D.A., Dinarello, C.A., Fujita, M., Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma. J. Invest. Dermatol. 133 (2013), 518–527.
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 518-527
-
-
Liu, W.1
Luo, Y.2
Dunn, J.H.3
Norris, D.A.4
Dinarello, C.A.5
Fujita, M.6
-
44
-
-
84941253821
-
Epigenetic inactivation of the candidate tumor suppressor gene ASC/TMS1 in human renal cell carcinoma and its role as a potential therapeutic target
-
Liu, Q., Jin, J., Ying, J., Cui, Y., Sun, M., Zhang, L., Fan, Y., Xu, B., Zhang, Q., Epigenetic inactivation of the candidate tumor suppressor gene ASC/TMS1 in human renal cell carcinoma and its role as a potential therapeutic target. Oncotarget 6 (2015), 22706–22723.
-
(2015)
Oncotarget
, vol.6
, pp. 22706-22723
-
-
Liu, Q.1
Jin, J.2
Ying, J.3
Cui, Y.4
Sun, M.5
Zhang, L.6
Fan, Y.7
Xu, B.8
Zhang, Q.9
-
45
-
-
84946020929
-
Expression profile of innate immune receptors, NLRs and AIM2: in human colorectal cancer: correlation with cancer stages and inflammasome components
-
Liu, R., Truax, A., Chen, L., Hu, P., Li, Z., Chen, J., Song, C., Chen, L., Ting, J.P., Expression profile of innate immune receptors, NLRs and AIM2: in human colorectal cancer: correlation with cancer stages and inflammasome components. Oncotarget 6 (2015), 33456–33469.
-
(2015)
Oncotarget
, vol.6
, pp. 33456-33469
-
-
Liu, R.1
Truax, A.2
Chen, L.3
Hu, P.4
Li, Z.5
Chen, J.6
Song, C.7
Chen, L.8
Ting, J.P.9
-
46
-
-
84885972767
-
Unsolved mysteries in NLR biology
-
Lupfer, C., Kanneganti, T., Unsolved mysteries in NLR biology. Front. Immunol., 4, 2013, 285.
-
(2013)
Front. Immunol.
, vol.4
, pp. 285
-
-
Lupfer, C.1
Kanneganti, T.2
-
47
-
-
84956825823
-
AIM2 inflammasome in infection, cancer, and autoimmunity Role in DNA sensing, inflammation, and innate immunity
-
Man, S.M., Karki, R., Kanneganti, T.D., AIM2 inflammasome in infection, cancer, and autoimmunity Role in DNA sensing, inflammation, and innate immunity. Eur. J. Immunol. 46 (2016), 269–280.
-
(2016)
Eur. J. Immunol.
, vol.46
, pp. 269-280
-
-
Man, S.M.1
Karki, R.2
Kanneganti, T.D.3
-
48
-
-
84899910966
-
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment
-
Mathews, R.J., Robinson, J.I., Battellino, M., Wong, C., Taylor, J.C., Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Eyre, S., Churchman, S.M., Wilson, A.G., Isaacs, J.D., Hyrich, K., Barton, A., Plant, D., Savic, S., Cook, G.P., Sarzi-Puttini, P., Emery, P., Barrett, J.H., Morgan, A.W., McDermott, M.F., Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment. Ann. Rheum. Dis. 73 (2014), 1202–1210.
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 1202-1210
-
-
Mathews, R.J.1
Robinson, J.I.2
Battellino, M.3
Wong, C.4
Taylor, J.C.5
Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS)6
Eyre, S.7
Churchman, S.M.8
Wilson, A.G.9
Isaacs, J.D.10
Hyrich, K.11
Barton, A.12
Plant, D.13
Savic, S.14
Cook, G.P.15
Sarzi-Puttini, P.16
Emery, P.17
Barrett, J.H.18
Morgan, A.W.19
McDermott, M.F.20
more..
-
49
-
-
84920377134
-
Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11
-
Meunier, E., Broz, P., Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11. DNA Cell Biol. 34 (2015), 1–5.
-
(2015)
DNA Cell Biol.
, vol.34
, pp. 1-5
-
-
Meunier, E.1
Broz, P.2
-
50
-
-
84874499122
-
Apoptosis-associated speck-like protein containing a CARD (ASC) expression profiles in familial Mediterranean fever (FMF) patients with different MEFV mutation patterns
-
Nalbantoglu, S., Tanyolac, B., Berdeli, A., Apoptosis-associated speck-like protein containing a CARD (ASC) expression profiles in familial Mediterranean fever (FMF) patients with different MEFV mutation patterns. Scand. J. Rheumatol. 42 (2013), 159–162.
-
(2013)
Scand. J. Rheumatol.
, vol.42
, pp. 159-162
-
-
Nalbantoglu, S.1
Tanyolac, B.2
Berdeli, A.3
-
51
-
-
79959369355
-
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
-
Normand, S., Delanoye-Crespin, A., Bressenot, A., Huot, L., Grandjean, T., Peyrin-Biroulet, L., Lemoine, Y., Hot, D., Chamaillard, M., Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 9601–9606.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 9601-9606
-
-
Normand, S.1
Delanoye-Crespin, A.2
Bressenot, A.3
Huot, L.4
Grandjean, T.5
Peyrin-Biroulet, L.6
Lemoine, Y.7
Hot, D.8
Chamaillard, M.9
-
52
-
-
84930088053
-
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells
-
Paugh, S.W., Bonten, E.J., Savic, D., Ramsey, L.B., Thierfelder, W.E., Gurung, P., Malireddi, R.K., Actis, M., Mayasundari, A., Min, J., Coss, D.R., Laudermilk, L.T., Panetta, J.C., McCorkle, J.R., Fan, Y., Crews, K.R., Stocco, G., Wilkinson, M.R., Ferreira, A.M., Cheng, C., Yang, W., Karol, S.E., Fernandez, C.A., Diouf, B., et al. NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells. Nat. Genet. 47 (2015), 607–614.
-
(2015)
Nat. Genet.
, vol.47
, pp. 607-614
-
-
Paugh, S.W.1
Bonten, E.J.2
Savic, D.3
Ramsey, L.B.4
Thierfelder, W.E.5
Gurung, P.6
Malireddi, R.K.7
Actis, M.8
Mayasundari, A.9
Min, J.10
Coss, D.R.11
Laudermilk, L.T.12
Panetta, J.C.13
McCorkle, J.R.14
Fan, Y.15
Crews, K.R.16
Stocco, G.17
Wilkinson, M.R.18
Ferreira, A.M.19
Cheng, C.20
Yang, W.21
Karol, S.E.22
Fernandez, C.A.23
Diouf, B.24
more..
-
53
-
-
84886384437
-
AIM2, an IFN-inducible cytosolic DNA sensor, in the development of benign prostate hyperplasia and prostate cancer
-
Ponomareva, L., Liu, H., Duan, X., Dickerson, E., Shen, H., Panchanathan, R., Choubey, D., AIM2, an IFN-inducible cytosolic DNA sensor, in the development of benign prostate hyperplasia and prostate cancer. Mol. Cancer Res. 11 (2013), 1193–1202.
-
(2013)
Mol. Cancer Res.
, vol.11
, pp. 1193-1202
-
-
Ponomareva, L.1
Liu, H.2
Duan, X.3
Dickerson, E.4
Shen, H.5
Panchanathan, R.6
Choubey, D.7
-
54
-
-
84862807232
-
TLR-induced NF-(B activation regulates NLRP3 expression in murine macrophages
-
Qiao, Y., Wang, P., Qi, J., Zhang, L., Gao, C., TLR-induced NF-(B activation regulates NLRP3 expression in murine macrophages. FEBS Lett. 586 (2012), 1022–1026.
-
(2012)
FEBS Lett.
, vol.586
, pp. 1022-1026
-
-
Qiao, Y.1
Wang, P.2
Qi, J.3
Zhang, L.4
Gao, C.5
-
55
-
-
84864600268
-
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria
-
Rathinam, V.A., Vanaja, S.K., Waggoner, L., Sokolovska, A., Becker, C., Stuart, L.M., Leong, J.M., Fitzgerald, K.A., TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. Cell. Microbiol. 150 (2012), 606–619.
-
(2012)
Cell. Microbiol.
, vol.150
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
Sokolovska, A.4
Becker, C.5
Stuart, L.M.6
Leong, J.M.7
Fitzgerald, K.A.8
-
56
-
-
84892149853
-
An update on PYRIN domain-containing pattern recognition receptors: from immunity to pathology
-
Ratsimandresy, R.A., Dorfleutner, A., Stehlik, C., An update on PYRIN domain-containing pattern recognition receptors: from immunity to pathology. Front. Immunol., 4, 2013, 440.
-
(2013)
Front. Immunol.
, vol.4
, pp. 440
-
-
Ratsimandresy, R.A.1
Dorfleutner, A.2
Stehlik, C.3
-
57
-
-
84882280029
-
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
-
Sagulenko, V., Thygesen, S.J., Sester, D.P., Idris, A., Cridland, J.A., Vajjhala, P.R., Roberts, T.L., Schroder, K., Vince, J.E., Hill, J.M., Silke, J., Stacey, K.J., AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death Differ. 20 (2013), 1149–1160.
-
(2013)
Cell Death Differ.
, vol.20
, pp. 1149-1160
-
-
Sagulenko, V.1
Thygesen, S.J.2
Sester, D.P.3
Idris, A.4
Cridland, J.A.5
Vajjhala, P.R.6
Roberts, T.L.7
Schroder, K.8
Vince, J.E.9
Hill, J.M.10
Silke, J.11
Stacey, K.J.12
-
58
-
-
10644274394
-
NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells
-
Sanz, C., Calasanz, M., Andreu, E., Richard, C., Prosper, F., Fernandez-Luna, J.L., NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells. Biochem. J. 384 (2004), 281–286.
-
(2004)
Biochem. J.
, vol.384
, pp. 281-286
-
-
Sanz, C.1
Calasanz, M.2
Andreu, E.3
Richard, C.4
Prosper, F.5
Fernandez-Luna, J.L.6
-
59
-
-
85007417755
-
The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease
-
Saresella, M., La Rosa, F., Piancone, F., Zoppis, M., Marventano, I., Calabrese, E., Rainone, V., Nemni, R., Mancuso, R., Clerici, M., The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease. Mol. Neurodegener., 11, 2016, 23.
-
(2016)
Mol. Neurodegener.
, vol.11
, pp. 23
-
-
Saresella, M.1
La Rosa, F.2
Piancone, F.3
Zoppis, M.4
Marventano, I.5
Calabrese, E.6
Rainone, V.7
Nemni, R.8
Mancuso, R.9
Clerici, M.10
-
60
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
Stienstra, R., van Dieppen, J.P., Tack, C.J., Zaki, M.H., van de Veerdonk, F.L., Perera, D., Neale, G.A., Hooiveld, G.J., Hijmans, A., Vroegrijk, I., van den Berg, S., Romijn, J., Rensen, P.C.N., Joosten, L.A.B., Netea, M.G., Kanneganti, T.D., Inflammasome is a central player in the induction of obesity and insulin resistance. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 15324–15329.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 15324-15329
-
-
Stienstra, R.1
van Dieppen, J.P.2
Tack, C.J.3
Zaki, M.H.4
van de Veerdonk, F.L.5
Perera, D.6
Neale, G.A.7
Hooiveld, G.J.8
Hijmans, A.9
Vroegrijk, I.10
van den Berg, S.11
Romijn, J.12
Rensen, P.C.N.13
Joosten, L.A.B.14
Netea, M.G.15
Kanneganti, T.D.16
-
61
-
-
84855989829
-
Inflammasomes in health and disease
-
Strowig, T., Henao-Mejia, J., Elinav, E., Flavell, R., Inflammasomes in health and disease. Nature 481 (2012), 278–286.
-
(2012)
Nature
, vol.481
, pp. 278-286
-
-
Strowig, T.1
Henao-Mejia, J.2
Elinav, E.3
Flavell, R.4
-
62
-
-
72849115852
-
Inflammasomes: too big to miss
-
Stutz, A., Golenbock, D.T., Latz, E., Inflammasomes: too big to miss. J. Clin. Invest. 119 (2009), 3502–3511.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3502-3511
-
-
Stutz, A.1
Golenbock, D.T.2
Latz, E.3
-
63
-
-
84863253461
-
NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han chinese
-
Sui, J., Li, H., Fang, Y., Liu, Y., Li, M., Zhong, B., Yang, F., Zou, Q., Wu, Y., NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han chinese. Arthritis Rheum. 64 (2012), 647–654.
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 647-654
-
-
Sui, J.1
Li, H.2
Fang, Y.3
Liu, Y.4
Li, M.5
Zhong, B.6
Yang, F.7
Zou, Q.8
Wu, Y.9
-
64
-
-
12144288983
-
Epigenetic inactivation of TMS1/ASC in ovarian cancer
-
Terasawa, K., Sagae, S., Toyota, M., Tsukada, K., Ogi, K., Satoh, A., Mita, H., Imai, K., Tokino, T., Kudo, R., Epigenetic inactivation of TMS1/ASC in ovarian cancer. Clin. Cancer Res. 10 (2004), 2000–2006.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 2000-2006
-
-
Terasawa, K.1
Sagae, S.2
Toyota, M.3
Tsukada, K.4
Ogi, K.5
Satoh, A.6
Mita, H.7
Imai, K.8
Tokino, T.9
Kudo, R.10
-
65
-
-
84868626486
-
Genetic variation and alterations of genes involved in NF(B/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer
-
Ungerbäck, J., Belennki, D., Jawad ul-Hassan, A., Fredrikson, M., Fransén, K., Elander, N., Verma, D., Söderkvist, P., Genetic variation and alterations of genes involved in NF(B/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer. Carcinogenesis 33 (2012), 2126–2134.
-
(2012)
Carcinogenesis
, vol.33
, pp. 2126-2134
-
-
Ungerbäck, J.1
Belennki, D.2
Jawad ul-Hassan, A.3
Fredrikson, M.4
Fransén, K.5
Elander, N.6
Verma, D.7
Söderkvist, P.8
-
66
-
-
84865389353
-
Critical role of caspase-1 in vascular inflammation and development of atherosclerosis inWestern diet-fed apolipoprotein E-deficientmice
-
Usui, F., Shirasuna, K., Kimura, H., Tatsumi, K., Kawashima, A., Hida, S., Sagara, J., Taniguchi, S., Takahashi, M., Critical role of caspase-1 in vascular inflammation and development of atherosclerosis inWestern diet-fed apolipoprotein E-deficientmice. Biochem. Biophys. Res. Commun. 425 (2012), 162–168.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.425
, pp. 162-168
-
-
Usui, F.1
Shirasuna, K.2
Kimura, H.3
Tatsumi, K.4
Kawashima, A.5
Hida, S.6
Sagara, J.7
Taniguchi, S.8
Takahashi, M.9
-
67
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar, B., Youm, Y., Ravussin, A., Galgani, J.E., Stadler, K., Mynatt, R.L., Ravussin, E., Stephens, J.M., Dixit, V.D., The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat. Med. 17 (2011), 179–188.
-
(2011)
Nat. Med.
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
68
-
-
84905562455
-
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
-
Vande Walle, L., Van Opdenbosch, O., Jacques, P., Fossoul, A., Verheugen, E., Vogel, P., Beyaert, R., Elewaut, D., Kanneganti, T.D., van Loo, G., Lamkanfi, M., Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature 512 (2014), 69–73.
-
(2014)
Nature
, vol.512
, pp. 69-73
-
-
Vande Walle, L.1
Van Opdenbosch, O.2
Jacques, P.3
Fossoul, A.4
Verheugen, E.5
Vogel, P.6
Beyaert, R.7
Elewaut, D.8
Kanneganti, T.D.9
van Loo, G.10
Lamkanfi, M.11
-
69
-
-
80055045773
-
IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes
-
Veeranki, S., Duan, X., Panchanathan, R., Liu, H., Choubey, D., IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes. PLoS One, 6, 2011, e27040.
-
(2011)
PLoS One
, vol.6
, pp. e27040
-
-
Veeranki, S.1
Duan, X.2
Panchanathan, R.3
Liu, H.4
Choubey, D.5
-
70
-
-
58149159542
-
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
-
Villani, A.C., Lemire, M., Fortin, G., Louis, E., Silverberg, M.S., Collette, C., Baba, N., Libioulle, C., Belaiche, J., Bitton, A., Gaudet, D., Cohen, A., Langelier, D., Fortin, P.R., Wither, J.E., Sarfati, M., Rutgeerts, P., Rioux, J.D., Vermeire, S., Hudson, T.J., Franchimont, D., Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat. Genet. 41 (2009), 71–76.
-
(2009)
Nat. Genet.
, vol.41
, pp. 71-76
-
-
Villani, A.C.1
Lemire, M.2
Fortin, G.3
Louis, E.4
Silverberg, M.S.5
Collette, C.6
Baba, N.7
Libioulle, C.8
Belaiche, J.9
Bitton, A.10
Gaudet, D.11
Cohen, A.12
Langelier, D.13
Fortin, P.R.14
Wither, J.E.15
Sarfati, M.16
Rutgeerts, P.17
Rioux, J.D.18
Vermeire, S.19
Hudson, T.J.20
Franchimont, D.21
more..
-
71
-
-
84958546545
-
Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells
-
Wang, Y., Kong, H., Zeng, X., Liu, W., Wang, Z., Yan, X., Wang, H., Xie, W., Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells. Oncol. Rep. 35 (2016), 2053–2064.
-
(2016)
Oncol. Rep.
, vol.35
, pp. 2053-2064
-
-
Wang, Y.1
Kong, H.2
Zeng, X.3
Liu, W.4
Wang, Z.5
Yan, X.6
Wang, H.7
Xie, W.8
-
72
-
-
79955038882
-
Fatty acidinduced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen, H., Gris, D., Lei, Y., Jha, S., Zhang, L., Huang, M.T., Brickey, W.J., Ting, J.P., Fatty acidinduced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat. Immunol. 12 (2011), 408–415.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
Brickey, W.J.7
Ting, J.P.8
-
73
-
-
84925423401
-
Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway
-
Xiao, J., Zhang, X.L., Fu, C., Han, R., Chen, W., Lu, Y., Ye, Z., Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway. Int. J. Mol. Med. 35 (2015), 1347–1354.
-
(2015)
Int. J. Mol. Med.
, vol.35
, pp. 1347-1354
-
-
Xiao, J.1
Zhang, X.L.2
Fu, C.3
Han, R.4
Chen, W.5
Lu, Y.6
Ye, Z.7
-
74
-
-
84920990887
-
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome
-
Yan, Y., Jiang, W., Liu, L., Wang, X., Ding, C., Tian, Z., Zhou, R., Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell 160 (2015), 62–73.
-
(2015)
Cell
, vol.160
, pp. 62-73
-
-
Yan, Y.1
Jiang, W.2
Liu, L.3
Wang, X.4
Ding, C.5
Tian, Z.6
Zhou, R.7
-
75
-
-
84953342756
-
The two faces of the inflammasome adaptor ASC in epithelial skin carcinogenesis
-
Yazdi, A.S., Drexler, S.K., The two faces of the inflammasome adaptor ASC in epithelial skin carcinogenesis. Clin. Exp. Rheumatol. 92 (2015), S94–96.
-
(2015)
Clin. Exp. Rheumatol.
, vol.92
, pp. S94-96
-
-
Yazdi, A.S.1
Drexler, S.K.2
-
76
-
-
0344827254
-
Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer
-
Yokoyama, T., Sagara, J., Guan, X., Masumoto, J., Takeoka, M., Komiyama, Y., Miyata, K., Higuchi, K., Taniguchi, S., Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer. Cancer Lett. 202 (2003), 101–108.
-
(2003)
Cancer Lett.
, vol.202
, pp. 101-108
-
-
Yokoyama, T.1
Sagara, J.2
Guan, X.3
Masumoto, J.4
Takeoka, M.5
Komiyama, Y.6
Miyata, K.7
Higuchi, K.8
Taniguchi, S.9
-
77
-
-
78049488908
-
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
-
Zaki, M.H., Vogel, P., Body-Malapel, M., Lamkanfi, M., Kanneganti, T.D., IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J. Immunol. 185 (2010), 4912–4920.
-
(2010)
J. Immunol.
, vol.185
, pp. 4912-4920
-
-
Zaki, M.H.1
Vogel, P.2
Body-Malapel, M.3
Lamkanfi, M.4
Kanneganti, T.D.5
-
78
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Zaki, M., Boyd, K.L., Vogel, P., Kastan, M.B., Lamkanfi, M., Kanneganti, T.D., The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 32 (2010), 379–391.
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
79
-
-
84927774890
-
The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus
-
Zhao, Y., Shao, F., The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus. Immunol. Rev. 265 (2015), 85–102.
-
(2015)
Immunol. Rev.
, vol.265
, pp. 85-102
-
-
Zhao, Y.1
Shao, F.2
-
80
-
-
84884350730
-
NLRP3 inflammasomes show high expression in aorta of patients with atherosclerosis
-
Zheng, F., Xing, S., Gong, Z., Xing, Q., NLRP3 inflammasomes show high expression in aorta of patients with atherosclerosis. Heart Lung Circ. 22 (2013), 746–750.
-
(2013)
Heart Lung Circ.
, vol.22
, pp. 746-750
-
-
Zheng, F.1
Xing, S.2
Gong, Z.3
Xing, Q.4
-
81
-
-
84910648303
-
The transcription factor GFI1 negatively regulates NLRP3 inflammasome activation in macrophages
-
Zhu, L., Meng, Q., Liang, S., Ma, Y., Li, R., Li, G., Zeng, H., The transcription factor GFI1 negatively regulates NLRP3 inflammasome activation in macrophages. FEBS Lett. 588 (2014), 4513–4519.
-
(2014)
FEBS Lett.
, vol.588
, pp. 4513-4519
-
-
Zhu, L.1
Meng, Q.2
Liang, S.3
Ma, Y.4
Li, R.5
Li, G.6
Zeng, H.7
-
82
-
-
84858643750
-
Inflammasomes in carcinogenesis and anticancer immune responses
-
Zitvogel, L., Kepp, O., Galluzzi, L., Kroemer, G., Inflammasomes in carcinogenesis and anticancer immune responses. Nat. Immunol. 13 (2012), 343–351.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 343-351
-
-
Zitvogel, L.1
Kepp, O.2
Galluzzi, L.3
Kroemer, G.4
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