Transcription factor ATF4 induces NLRP1 inflammasome expression during endoplasmic reticulum stress

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  D'Osualdo, Andrea ^a   Anania, Veronica G ^b   Yu, Kebing ^b   Lill, Jennie R ^b   Kaufman, Randal J ^c   Matsuzawa, Shu Ichi ^a   Reed, John C ^a,d  

^a BURNHAM INSTITUTE   (United States)

^b GENENTECH INC   (United States)

^c Degenerative Diseases Research Program   (United States)

^d F Hoffmann La Roche   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; INFLAMMASOME; NLRP1 PROTEIN; PKR LIKE ENDOPLASMIC RETICULUM RESIDENT KINASE; PROTEIN IRE1; PROTEIN IRE1ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; APOPTOSIS REGULATORY PROTEIN; DNA BINDING PROTEIN; ERN1 PROTEIN, HUMAN; NLRP1 PROTEIN, HUMAN; PERK KINASE; PROTEIN BINDING; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; REGULATORY FACTOR X TRANSCRIPTION FACTOR; RIBONUCLEASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR; XBP1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PROMOTER REGION; PROTEIN BINDING; RNA SPLICING; UPREGULATION; CHEMISTRY; CRISPR CAS SYSTEM; ENDOPLASMIC RETICULUM; GENETICS; HCT 116 CELL LINE; HELA CELL LINE; JURKAT CELL LINE; K-562 CELL LINE; METABOLISM; MUTAGENESIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 4; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS REGULATORY PROTEINS; CRISPR-CAS SYSTEMS; DNA-BINDING PROTEINS; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HCT116 CELLS; HELA CELLS; HUMANS; INFLAMMASOMES; JURKAT CELLS; K562 CELLS; MUTAGENESIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RNA SPLICING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UP-REGULATION; X-BOX BINDING PROTEIN 1;

EID: 84939152599     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130635     Document Type: Article

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