The transcription factor GFI1 negatively regulates NLRP3 inflammasome activation in macrophages

FEBS Letters

Volumn 588, Issue 23, 2014, Pages 4513-4519

  Zhu, Liuluan ^a,b   Meng, Qingcai ^a,b   Liang, Shuntao ^a,b   Ma, Yaluan ^c   Li, Rui ^a,b   Li, Guoli ^a,b   Zeng, Hui ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Key Laboratory of Emerging Infectious Diseases   (China)

^c INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Gfi1; IL 1 ; Inflammasome; Macrophage; NLRP3

Indexed keywords

CRYOPYRIN; GROWTH FACTOR INDEPENDENCE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; DNA BINDING PROTEIN; GFI1 PROTEIN, MOUSE; INFLAMMASOME; TOLL LIKE RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; MOUSE; NLRP3 GENE; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MACROPHAGE; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SECRETION (PROCESS);

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES; MICE; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84910648303     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.10.025     Document Type: Article

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