NLRC5 mediates cytokine secretion in RAW264.7 macrophages and modulated by the JAK2/STAT3 pathway

Inflammation

Volumn 37, Issue 3, 2014, Pages 835-847

  Li, Lin ^a   Xu, Tao ^a   Huang, Cheng ^a   Peng, Yunyun ^a   Li, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

AG490; IL 6; JAK2 siRNA; JAK2 STAT3; NLRC5; TNF

Indexed keywords

CYTOKINE; INTERLEUKIN 6; JANUS KINASE 2; LIPOPOLYSACCHARIDE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NOD LIKE RECEPTOR FAMILY CARD DOMAIN CONTAINING 5; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; SMALL INTERFERING RNA; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE; ENZYME INHIBITOR; JAK2 PROTEIN, MOUSE; MESSENGER RNA; NLRC5 PROTEIN, MOUSE; SIGNAL PEPTIDE; STAT3 PROTEIN, MOUSE; TYRPHOSTIN;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; GENE SILENCING; INNATE IMMUNITY; MACROPHAGE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DOWN REGULATION; GENETICS; IMMUNOLOGY; RNA INTERFERENCE; SECRETION (PROCESS);

ANIMALS; CELL LINE; CYTOKINES; DOWN-REGULATION; ENZYME INHIBITORS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JANUS KINASE 2; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR-ALPHA; TYRPHOSTINS;

EID: 84902551656     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9804-y     Document Type: Article

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