NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells

Biochemical Journal

Volumn 384, Issue 2, 2004, Pages 281-286

  Sanz, Cristina ^a   Calasanz, Maria J ^b   Andreu, Enrique ^c   Richard, Carlos ^a   Prosper, Felipe ^c   Fernandez Luna, Jose L ^a  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

^c UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Blast cell; cAMP response element binding protein (CREB); Inflammation; Leukaemia; NALP1; Tumour cell

Indexed keywords

BLOOD; CELLS; PROTEINS; RNA; TUMORS;

MONONUCLEAR CELLS; PROTEIN KINASES;

BIOCHEMISTRY;

CD15 ANTIGEN; CD3 ANTIGEN; CD34 ANTIGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOPLASM PROTEIN; MESSENGER RNA; NALP1 PROTEIN; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ARTICLE; BLAST CELL; BLOOD CELL; BONE MARROW CELL; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; GRANULOCYTE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; LEUKEMIA CELL; MONOCYTE; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN TARGETING; REDUCTION; T LYMPHOCYTE; THYROID CARCINOMA; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HEMATOPOIETIC STEM CELLS; HUMANS; K562 CELLS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LEUKEMIA, MYELOID; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC;

EID: 10644274394     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040867     Document Type: Article

References (28)

1. Tschopp, J., Martinen, F. and Burns, K. (2003) NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol. 4, 95-104
2. Hlaing, T., Quo, R. F., Dilley, K. A., Loussia, J. M., Morrish, T. A., Shi, M. M., Vincenz, C. and Ward, P. A. (2001) Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins. J. Biol. Chem. 276, 9230-9238
3. Chu, Z. L., Pio, F., Xie, Z., Welsh, K., Krajewska, M., Krajewski, S., Godzik, A. and Reed, J. C. (2001) A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol. Chem. 276, 9239-9245
4. Martinon, F., Burns, K. and Tschopp, J. (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell 10, 417-426
5. Harton, J. A., Linhoff, M. W., Zhang, J. and Ting, J. P. (2002) Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. J. Immunol. 169, 4088-4093
6. Inohara, N., Ogura, Y., Chen, F. F., Muto, A. and Nunez, G. (2001) Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J. Biol. Chem. 276, 2551-2554
7. Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K., Inamura, S., Kusumoto, S., Hashimoto, M. et al. (2003) Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J. Biol. Chem. 278, 5509-5512
8. Silverman, N. and Maniatis, T. (2001) NF-κB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15, 2321-2342
9. Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V. and Baldwin, Jr, A. S. (1998) NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and C-IAP1 and C-IAP2 to suppress caspase-8 activation. Science 281, 1680-1683
10. Ogura, Y., Bonen, D., Inohara, N., Nicolae, D., Chen, F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. et al. (2001) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606
11. Hugot, J., Chamaillard, M., Zouali, H., Lesage, S., Cezard, J., Belaiche, J., Aimer, S., Tysk, C., O'Morain, C., Gassull, M. et al. (2001) Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411, 599-603
12. Miceli-Richard, C., Lesage, S., Rybojad, M., Prieur, A., Manouvrier-Hanu, S., Hafner, R., Chamaillard, M., Zouali, H., Thomas, G. and Hugot, J, (2001) CARD15 mutations in Blau syndrome. Nat. Genet. 29, 19-20
13. Dode, C., Le Du, N., Cuisset, L., Letourneur, F., Berthelot, J. M., Vaudour, G., Meyrier, A., Watts, R. A., Scott, D. G., Nicholls, A. et al. (2002) New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes. Am. J. Hum. Genet. 70, 1498-1506
14. Robles, A. I., Bemmels, N. A., Foraker, A. B. and Harris, C. C. (2001) APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis. Cancer Res. 61, 6660-6664
15. Gutierrez, O., Pipaon, C., Inohara, N., Fontalba, A., Ogura, Y., Prosper, F., Nunez, G. and Fernandez-Luna, J. L (2002) Induction of Nod2 in myelomonocytic and intestinal epithelial cells via nuclear factor-κB activation. J. Biol. Chem. 277, 41701-41705
16. Riccio, A., Ahn, S., Davenport, C. M., Blendy, J. A. and Ginty, D. D. (1999) Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286, 2358-2361
17. Benito, A., Silva, M., Grillot, D., Nunez, G. and Fernandez-Luna, J. (1996) Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bel-XL. Blood 87, 3837-3843
18. Ogura, Y., Inohara, N., Benito, A., Chen, F. F., Yamaoka, S. and Nunez, G. (2001) Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB. J. Biol. Chem. 276, 4812-4818
19. Sanz, C., Benito, A., Silva, M., Albeila, B., Richard, C., Segovia, J. C., Insunza, A., Bueren, J. A. and Fernandez-Luna, J. L. (1997) The expression of Bcl-x is downregulated during differentiation of human hematopoietic progenitor cells along the granulocyte but not the monocyte/macrophage lineage. Blood 89, 3199-3204
20. Ji, L., Mochon, E., Arcinas, M. and Boxer, L. M. (1996) CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas. J. Biol. Chem. 271, 22687-22691
21. c cytokine receptor-induced stimulation of cAMP response element binding protein phosphorylation requires protein kinase C in myeloid cells: a novel cytokine signal transduction cascade. J. Immunol. 167, 4303-4310
22. Boer, A. K., Drayer, A. L., Rui, H. and Veilenga, E. (2002) Prostaglandin-E2 enhances EPO-mediated STATS transcriptional activity by serine phosphorylation of CREB. Blood 100, 467-473
23. Beaupre, D. M., Talpaz, M., Marini, 3rd, F. C., Cristiano, R. J., Roth, J. A., Estrov, Z., Albitar, M., Freedman, M. H. and Kurzrock, R. (1999) Autocrine interleukin-1β production in leukemia: evidence for the involvement of mutated RAS. Cancer Res. 59, 2971-2980
24. Sitaraman, S. V., Merlin, D., Wang, L., Wong, M., Gewirtz, A. T., Si-Tahar, M. and Madara, J. L. (2001) Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6. J. Clin. Invest. 107, 861-869
25. Schroer, K., Zhu, Y., Saunders, M. A., Deng, W. G., Xu, X. M., Meyer-Kirchrath, J. and Wu, K. K. (2002) Obligatory role of cyclic adenosine monophosphate response element in cyclooxygenase-2 promoter induction and feedback regulation by inflammatory mediators. Circulation 105, 2760-2765
26. Shaywitz, A. J. and Greenberg, M. E. (1999) CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu. Rev. Biochem. 68, 821-861
27. Xie, H. and Rothstein, T. L. (1995) Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig. J. Immunol. 154, 1717-1723
28. Meinkoth, J. L., Alberts, A. S., Went, W., Fantozzi, D., Taylor, S. S., Hagiwara, M., Montminy, M. and Feramisco, J. R. (1993) Signal transduction through the cAMP-dependent protein kinase. Mol. Cell. Biochem. 127-128, 179-186