Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway

International Journal of Molecular Medicine

Volumn 35, Issue 5, 2015, Pages 1347-1354

  Xiao, Jing ^a   Zhang, Xiao Li ^a   Fu, Chensheng ^a   Han, Rui ^a   Chen, Weijun ^a   Lu, Yijun ^a   Ye, Zhibin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Caspase 1; Human primary renal proximal tubule epithelial cells; Interleukin 1 ; Nod like receptor protein 3; Soluble uric acid; Toll like receptor 4

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; RNA; TOLL LIKE RECEPTOR 4; URIC ACID; CARRIER PROTEIN; NLRP3 PROTEIN, HUMAN;

ARTICLE; CELL VIABILITY; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HYPERURICEMIA; INNATE IMMUNITY; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EPITHELIUM; MTT ASSAY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URIC ACID BLOOD LEVEL; WESTERN BLOTTING; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

CARRIER PROTEINS; CELL SURVIVAL; CELLS, CULTURED; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMASOMES; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; KIDNEY TUBULES, PROXIMAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; URIC ACID;

EID: 84925423401     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2148     Document Type: Article

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