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Volumn 11, Issue 10, 2013, Pages 1193-1202

AIM2, an IFN-inducible cytosolic DNA sensor, in the development of benign prostate hyperplasia and prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; PROTEIN AIM 2; UNCLASSIFIED DRUG; AIM2 PROTEIN, HUMAN; DNA; DNA BINDING PROTEIN; NUCLEAR PROTEIN;

EID: 84886384437     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-13-0145     Document Type: Article
Times cited : (99)

References (56)
  • 1
    • 0034307013 scopus 로고    scopus 로고
    • Molecular genetics of prostate cancer
    • Abate-Shen C, Shen MM. Molecular genetics of prostate cancer. Genes Dev 2000;14:2410-34.
    • (2000) Genes Dev , vol.14 , pp. 2410-2434
    • Abate-Shen, C.1    Shen, M.M.2
  • 4
    • 34548436073 scopus 로고    scopus 로고
    • Inflammation, atrophy, and prostate carcinogenesis
    • De Marzo AM, Nakai Y, Nelson WG. Inflammation, atrophy, and prostate carcinogenesis. Urol Oncol 2007;25:398-400.
    • (2007) Urol Oncol , vol.25 , pp. 398-400
    • De Marzo, A.M.1    Nakai, Y.2    Nelson, W.G.3
  • 6
    • 44449101570 scopus 로고    scopus 로고
    • Inflammation and prostate cancer: A focus on infections
    • Sutcliffe S, Platz EA. Inflammation and prostate cancer: a focus on infections. Curr Urol Rep 2008;9:243-49.
    • (2008) Curr Urol Rep , vol.9 , pp. 243-249
    • Sutcliffe, S.1    Platz, E.A.2
  • 7
    • 41749118209 scopus 로고    scopus 로고
    • Inflammation, infection, and prostate cancer
    • Klein EA, Silverman R. Inflammation, infection, and prostate cancer. Curr Opin Urol 2008;18:315-19.
    • (2008) Curr Opin Urol , vol.18 , pp. 315-319
    • Klein, E.A.1    Silverman, R.2
  • 8
    • 77954939175 scopus 로고    scopus 로고
    • Prostate cancer as a model for tumor immunotherapy
    • Drake CG. Prostate cancer as a model for tumor immunotherapy. Nat Rev Immunol 2010;10:580-93.
    • (2010) Nat Rev Immunol , vol.10 , pp. 580-593
    • Drake, C.G.1
  • 9
    • 84871918357 scopus 로고    scopus 로고
    • The link between benign prostatic hyperplasia and prostate cancer
    • Orsted DD, Bojesen SE. The link between benign prostatic hyperplasia and prostate cancer. Nat Rev Urol 2012;10:49-54.
    • (2012) Nat Rev Urol , vol.10 , pp. 49-54
    • Orsted, D.D.1    Bojesen, S.E.2
  • 12
    • 80051535218 scopus 로고    scopus 로고
    • Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model
    • Birbach A, Eisenbarth D, Kozakowski N, Ladenhauf E, Schmidt-Supprian M, Schmid JA, et al. Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model. Neoplasia 2011;13:692-703.
    • (2011) Neoplasia , vol.13 , pp. 692-703
    • Birbach, A.1    Eisenbarth, D.2    Kozakowski, N.3    Ladenhauf, E.4    Schmidt-Supprian, M.5    Schmid, J.A.6
  • 13
    • 0035344461 scopus 로고    scopus 로고
    • A weak signal for strong responses: Interferon- alpha/beta revisited
    • Taniguchi T, Takaoka A. A weak signal for strong responses: interferon- alpha/beta revisited. Nat Rev Mol Cell Biol 2001;2:378-86.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 378-386
    • Taniguchi, T.1    Takaoka, A.2
  • 14
    • 27744526416 scopus 로고    scopus 로고
    • Regulation of the type-I IFN induction: A current view
    • Honda K, Yanai H, Takaoka A, Taniguchi T. Regulation of the type-I IFN induction: a current view. Int Immunol 2005;17:1367-78.
    • (2005) Int Immunol , vol.17 , pp. 1367-1378
    • Honda, K.1    Yanai, H.2    Takaoka, A.3    Taniguchi, T.4
  • 16
    • 0037382970 scopus 로고    scopus 로고
    • Cellular senescence in the pathogenesis of benign prostatic hyperplasia
    • Castro P, Giri D, Lamb D, Ittmann M. Cellular senescence in the pathogenesis of benign prostatic hyperplasia. Prostate 2003;55: 30-8.
    • (2003) Prostate , vol.55 , pp. 30-38
    • Castro, P.1    Giri, D.2    Lamb, D.3    Ittmann, M.4
  • 17
    • 0036829854 scopus 로고    scopus 로고
    • Characterization of epithelial senescence by serial analysis of gene expression: Identification of genes potentially involved in prostate cancer
    • Untergasser G, Koch HB, Menssen A, Hermeking H. Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer. Cancer Res 2002;62:6255-62.
    • (2002) Cancer Res , vol.62 , pp. 6255-6262
    • Untergasser, G.1    Koch, H.B.2    Menssen, A.3    Hermeking, H.4
  • 18
    • 0037022602 scopus 로고    scopus 로고
    • Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression
    • Shou J, Soriano R, Hayward SW, Cunha GR, Williams PM, Gao WQ, et al. Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression. Proc Natl Acad Sci U S A 2002;99:2830-5.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2830-2835
    • Shou, J.1    Soriano, R.2    Hayward, S.W.3    Cunha, G.R.4    Williams, P.M.5    Gao, W.Q.6
  • 19
    • 53649109801 scopus 로고    scopus 로고
    • Critical pathways in cellular senescence and immortalization revealed by gene expression profiling
    • Fridman AL, Tainsky MA. Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. Oncogene 2008;27:5975-87.
    • (2008) Oncogene , vol.27 , pp. 5975-5987
    • Fridman, A.L.1    Tainsky, M.A.2
  • 20
    • 79956007831 scopus 로고    scopus 로고
    • Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts
    • Duan X, Ponomareva L, Veeranki S, Panchanathan R, Dickerson E, Choubey D, et al. Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts. Mol Cancer Res 2011;9:589-602.
    • (2011) Mol Cancer Res , vol.9 , pp. 589-602
    • Duan, X.1    Ponomareva, L.2    Veeranki, S.3    Panchanathan, R.4    Dickerson, E.5    Choubey, D.6
  • 21
    • 0042567245 scopus 로고    scopus 로고
    • Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence
    • Xin H, Curry J, Johnstone RW, Nickoloff BJ, Choubey D. Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence. Oncogene 2003;22:4831-40.
    • (2003) Oncogene , vol.22 , pp. 4831-4840
    • Xin, H.1    Curry, J.2    Johnstone, R.W.3    Nickoloff, B.J.4    Choubey, D.5
  • 22
    • 4344716680 scopus 로고    scopus 로고
    • Role of IFI 16 in cellular senescence of human fibroblasts
    • Xin H, Pereira-Smith OM, Choubey D. Role of IFI 16 in cellular senescence of human fibroblasts. Oncogene 2004;23:6209-17.
    • (2004) Oncogene , vol.23 , pp. 6209-6217
    • Xin, H.1    Pereira-Smith, O.M.2    Choubey, D.3
  • 23
    • 77949881221 scopus 로고    scopus 로고
    • The senescenceassociated secretory phenotype: The dark side of tumor suppression
    • Coppé JP, Desprez PY, Krtolica A, Campisi J. The senescenceassociated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 2010;5:99-118.
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 24
    • 84856209016 scopus 로고    scopus 로고
    • Emerging role of NF-kB signaling in the induction of senescence- associated secretory phenotype (SASP)
    • Salminen A, Kauppinen A, Kaarniranta K. Emerging role of NF-kB signaling in the induction of senescence-associated secretory phenotype (SASP). Cell Signal 2012;24:835-45.
    • (2012) Cell Signal , vol.24 , pp. 835-845
    • Salminen, A.1    Kauppinen, A.2    Kaarniranta, K.3
  • 25
    • 33750372462 scopus 로고    scopus 로고
    • Apoptotic cell death increases with senescence in normal human dermal fibroblast cultures
    • Mammone T, Gan D, Foyouzi-Youssefi R. Apoptotic cell death increases with senescence in normal human dermal fibroblast cultures. Cell Biol Int 2006;30:903-9.
    • (2006) Cell Biol Int , vol.30 , pp. 903-909
    • Mammone, T.1    Gan, D.2    Foyouzi-Youssefi, R.3
  • 29
    • 84869504451 scopus 로고    scopus 로고
    • Inflammasomes and their roles in health and disease
    • Lamkanfi M, Dixit VM. Inflammasomes and their roles in health and disease. Annu Rev Cell Dev Biol 2012;28:137-61.
    • (2012) Annu Rev Cell Dev Biol , vol.28 , pp. 137-161
    • Lamkanfi, M.1    Dixit, V.M.2
  • 30
    • 80052152283 scopus 로고    scopus 로고
    • The PYHIN protein family as mediators of host defenses
    • Schattgen SA, Fitzgerald KA. The PYHIN protein family as mediators of host defenses. Immunol Rev 2011;243:109-18.
    • (2011) Immunol Rev , vol.243 , pp. 109-118
    • Schattgen, S.A.1    Fitzgerald, K.A.2
  • 31
    • 77953583256 scopus 로고    scopus 로고
    • Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: Role in inflammation and autoimmunity
    • Choubey D, Duan X, Dickerson E, Ponomareva L, Panchanathan R, Shen H, et al. Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity. J Interferon Cytokine Res 2010;30:371-80.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 371-380
    • Choubey, D.1    Duan, X.2    Dickerson, E.3    Ponomareva, L.4    Panchanathan, R.5    Shen, H.6
  • 32
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010;140:821-32.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 33
    • 70350366890 scopus 로고    scopus 로고
    • Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis
    • Abdul-Sater AA, Koo E, Hacker G, Ojcius DM. Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. J Biol Chem 2009;284:26789-96.
    • (2009) J Biol Chem , vol.284 , pp. 26789-26796
    • Abdul-Sater, A.A.1    Koo, E.2    Hacker, G.3    Ojcius, D.M.4
  • 36
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 2009;458:509-13.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 37
    • 60749136484 scopus 로고    scopus 로고
    • An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
    • Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 2009;10:266-72.
    • (2009) Nat Immunol , vol.10 , pp. 266-272
    • Burckstummer, T.1    Baumann, C.2    Bluml, S.3    Dixit, E.4    Durnberger, G.5    Jahn, H.6
  • 38
    • 0029202881 scopus 로고
    • Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1
    • Hayward SW, Dahiya R, Cunha GR, Bartek J, Deshpande N, Narayan P, et al. Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1. In Vitro Cell Dev Biol Anim 1995;31:14-24.
    • (1995) In Vitro Cell Dev Biol Anim , vol.31 , pp. 14-24
    • Hayward, S.W.1    Dahiya, R.2    Cunha, G.R.3    Bartek, J.4    Deshpande, N.5    Narayan, P.6
  • 39
    • 33344475446 scopus 로고    scopus 로고
    • Androgen receptor autoregulates its expression by a negative feedback loop through upregulation of IFI16 protein
    • Alimirah F, Chen J, Xin H, Choubey D. Androgen receptor autoregulates its expression by a negative feedback loop through upregulation of IFI16 protein. FEBS Lett 2006;580:1659-64.
    • (2006) FEBS Lett , vol.580 , pp. 1659-1664
    • Alimirah, F.1    Chen, J.2    Xin, H.3    Choubey, D.4
  • 40
    • 84857364644 scopus 로고    scopus 로고
    • DNA-responsive inflammasomes and their regulators in autoimmunity
    • Choubey D. DNA-responsive inflammasomes and their regulators in autoimmunity. Clin Immunol 2012;142:223-31.
    • (2012) Clin Immunol , vol.142 , pp. 223-231
    • Choubey, D.1
  • 41
    • 15944387692 scopus 로고    scopus 로고
    • Z-VADfmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species
    • Cowburn AS, White JF, Deighton J, Walmsley SR, Chilvers ER. z-VADfmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood 2005;105:2970-72.
    • (2005) Blood , vol.105 , pp. 2970-2972
    • Cowburn, A.S.1    White, J.F.2    Deighton, J.3    Walmsley, S.R.4    Chilvers, E.R.5
  • 42
    • 0034051249 scopus 로고    scopus 로고
    • Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia
    • Choi J, Shendrik I, Peacocke M, Peehl D, Buttyan R, Ikeguchi EF, et al. Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia. Urology 2000; 56:160-66.
    • (2000) Urology , vol.56 , pp. 160-166
    • Choi, J.1    Shendrik, I.2    Peacocke, M.3    Peehl, D.4    Buttyan, R.5    Ikeguchi, E.F.6
  • 43
    • 0031431599 scopus 로고    scopus 로고
    • Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18
    • Bello D, Webber MM, Kleinman HK, Wartinger DD, Rhim JS. Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18. Carcinogenesis 1997;18:1215-23.
    • (1997) Carcinogenesis , vol.18 , pp. 1215-1223
    • Bello, D.1    Webber, M.M.2    Kleinman, H.K.3    Wartinger, D.D.4    Rhim, J.S.5
  • 44
    • 80055045773 scopus 로고    scopus 로고
    • IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes
    • Veeranki S, Duan X, Panchanathan R, Liu H, Choubey D. IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes. PLoS ONE 2011;6:e27040.
    • (2011) PLoS ONE , vol.6
    • Veeranki, S.1    Duan, X.2    Panchanathan, R.3    Liu, H.4    Choubey, D.5
  • 45
    • 84655165036 scopus 로고    scopus 로고
    • Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: Regulation of subcellular localization
    • Veeranki S, Choubey D. Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localization. Mol Immunol 2012;49: 567-71.
    • (2012) Mol Immunol , vol.49 , pp. 567-571
    • Veeranki, S.1    Choubey, D.2
  • 46
    • 35349011610 scopus 로고    scopus 로고
    • The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers
    • Woerner SM, Kloor M, Schwitalle Y, Youmans H, Doeberitz MK, Gebert J, et al. The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers. Genes Chromosomes Cancer 2007;46:1080-89
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 1080-1089
    • Woerner, S.M.1    Kloor, M.2    Schwitalle, Y.3    Youmans, H.4    Doeberitz, M.K.5    Gebert, J.6
  • 47
    • 0036895805 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes
    • Hasegawa S, Furukawa Y, Li M, Satoh S, Kato T, Watanabe T, et al. Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes. Cancer Res 2002;62:7012-17.
    • (2002) Cancer Res , vol.62 , pp. 7012-7017
    • Hasegawa, S.1    Furukawa, Y.2    Li, M.3    Satoh, S.4    Kato, T.5    Watanabe, T.6
  • 48
    • 79953046715 scopus 로고    scopus 로고
    • Leukocyte DNA methylation signature differentiates pancreatic cancer patients from healthy controls
    • Pedersen KS, Bamlet WR, Oberg AL, de Andrade M, Matsumoto ME, Tang H, et al. Leukocyte DNA methylation signature differentiates pancreatic cancer patients from healthy controls. PLoS ONE 2011;6:e18223.
    • (2011) PLoS ONE , vol.6
    • Pedersen, K.S.1    Bamlet, W.R.2    Oberg, A.L.3    De Andrade, M.4    Matsumoto, M.E.5    Tang, H.6
  • 49
    • 0030775488 scopus 로고    scopus 로고
    • Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma
    • DeYoung KL, Ray ME, Su YA, Anzick SL, Johnstone RW, Trapani JA, et al. Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma. Oncogene 1997;15:453-57.
    • (1997) Oncogene , vol.15 , pp. 453-457
    • Deyoung, K.L.1    Ray, M.E.2    Su, Y.A.3    Anzick, S.L.4    Johnstone, R.W.5    Trapani, J.A.6
  • 50
    • 33644860451 scopus 로고    scopus 로고
    • AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model
    • Chen IF, Ou-Yang F, Hung JY, Liu JC, Wang H, Wang SC, et al. AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model. Mol Cancer Ther 2006; 5:1-7
    • (2006) Mol Cancer Ther , vol.5 , pp. 1-7
    • Chen, I.F.1    Ou-Yang, F.2    Hung, J.Y.3    Liu, J.C.4    Wang, H.5    Wang, S.C.6
  • 51
    • 77949892176 scopus 로고    scopus 로고
    • Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells
    • Patsos G, Germann A, Gebert J, Dihlmann S. Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells. Int J Cancer 2010;126: 1838-49.
    • (2010) Int J Cancer , vol.126 , pp. 1838-1849
    • Patsos, G.1    Germann, A.2    Gebert, J.3    Dihlmann, S.4
  • 53
    • 0033559189 scopus 로고    scopus 로고
    • Restoration of transforming growth factor beta signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis
    • Guo Y, Kyprianou N. Restoration of transforming growth factor beta signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis. Cancer Res 1999;59:1366-71.
    • (1999) Cancer Res , vol.59 , pp. 1366-1371
    • Guo, Y.1    Kyprianou, N.2
  • 54
    • 0035117041 scopus 로고    scopus 로고
    • Loss of caspase-1 and caspase-3 protein expression in human prostate cancer
    • Winter RN, Kramer A, Borkowski A, Kyprianou N. Loss of caspase-1 and caspase-3 protein expression in human prostate cancer. Cancer Res 2001;61:1227-32.
    • (2001) Cancer Res , vol.61 , pp. 1227-1232
    • Winter, R.N.1    Kramer, A.2    Borkowski, A.3    Kyprianou, N.4
  • 56
    • 1642288517 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1alpha and IL-1beta) and its receptors (IL-1RI, IL-1RII, and IL-1Ra) in prostate carcinoma
    • Ricote M, García-Tuñón I, Bethencourt FR, Fraile B, Paniagua R, Royuela M, et al. Interleukin-1 (IL-1alpha and IL-1beta) and its receptors (IL-1RI, IL-1RII, and IL-1Ra) in prostate carcinoma. Cancer 2004;100: 1388-96.
    • (2004) Cancer , vol.100 , pp. 1388-1396
    • Ricote, M.1    García-Tuñón, I.2    Bethencourt, F.R.3    Fraile, B.4    Paniagua, R.5    Royuela, M.6


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