-
1
-
-
84860375295
-
Inflammation & apoptosis in spinal cord injury
-
Zhang N, Yin Y, Xu SJ, Wu YP, Chen WS. Inflammation & apoptosis in spinal cord injury. Indian J Med Res. 2012;135:287-96.
-
(2012)
Indian J Med Res
, vol.135
, pp. 287-296
-
-
Zhang, N.1
Yin, Y.2
Xu, S.J.3
Wu, Y.P.4
Chen, W.S.5
-
2
-
-
33645786025
-
A novel role of phospholipase A2 in mediating spinal cord secondary injury
-
Liu NK, Zhang YP, Titsworth WL, Jiang X, Han S, Lu PH, et al. A novel role of phospholipase A2 in mediating spinal cord secondary injury. Ann Neurol. 2006;59:606-19.
-
(2006)
Ann Neurol
, vol.59
, pp. 606-619
-
-
Liu, N.K.1
Zhang, Y.P.2
Titsworth, W.L.3
Jiang, X.4
Han, S.5
Lu, P.H.6
Shields, C.B.7
Xu, X.M.8
-
3
-
-
84889030920
-
Managing inflammation after spinal cord injury through manipulation of macrophage function
-
Ren Y, Young W. Managing inflammation after spinal cord injury through manipulation of macrophage function. Neural Plast. 2013;2013:945034.
-
(2013)
Neural Plast
, vol.2013
, pp. 945034
-
-
Ren, Y.1
Young, W.2
-
4
-
-
16944363478
-
Neuronal and glial apoptosis after traumatic spinal cord injury
-
Liu XZ, Xu XM, Hu R, Du C, Zhang SX, McDonald JW, et al. Neuronal and glial apoptosis after traumatic spinal cord injury. J Neurosci. 1997;17:5395-406.
-
(1997)
J Neurosci
, vol.17
, pp. 5395-5406
-
-
Liu, X.Z.1
Xu, X.M.2
Hu, R.3
Du, C.4
Zhang, S.X.5
McDonald, J.W.6
Dong, H.X.7
Wu, Y.J.8
Fan, G.S.9
Jacquin, M.F.10
-
5
-
-
0037379603
-
Gene profiling in spinal cord injury shows role of cell cycle in neuronal death
-
Di Giovanni S, Knoblach SM, Brandoli C, Aden SA, Hoffman EP, Faden AI. Gene profiling in spinal cord injury shows role of cell cycle in neuronal death. Ann Neurol. 2003;53:454-68.
-
(2003)
Ann Neurol
, vol.53
, pp. 454-468
-
-
Giovanni, S.1
Knoblach, S.M.2
Brandoli, C.3
Aden, S.A.4
Hoffman, E.P.5
Faden, A.I.6
-
7
-
-
84927659436
-
Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death
-
Liu S, Sarkar C, Dinizo M, Faden AI, Koh EY, Lipinski MM, et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 2015;6, e1582.
-
(2015)
Cell Death Dis
, vol.6
-
-
Liu, S.1
Sarkar, C.2
Dinizo, M.3
Faden, A.I.4
Koh, E.Y.5
Lipinski, M.M.6
Wu, J.7
-
8
-
-
3042816808
-
The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration
-
Park E, Velumian AA, Fehlings MG. The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration. J Neurotrauma. 2004;21:754-74.
-
(2004)
J Neurotrauma
, vol.21
, pp. 754-774
-
-
Park, E.1
Velumian, A.A.2
Fehlings, M.G.3
-
9
-
-
84941189756
-
Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation
-
Kaushal V, Dye R, Pakavathkumar P, Foveau B, Flores J, Hyman B, et al. Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation. Cell Death Differ. 2015;22:1676-86.
-
(2015)
Cell Death Differ
, vol.22
, pp. 1676-1686
-
-
Kaushal, V.1
Dye, R.2
Pakavathkumar, P.3
Foveau, B.4
Flores, J.5
Hyman, B.6
Ghetti, B.7
Koller, B.H.8
LeBlanc, A.C.9
-
10
-
-
84897570627
-
Pyroptotic neuronal cell death mediated by the AIM2 inflammasome
-
Adamczak SE, de Rivero Vaccari JP, Dale G, Brand 3rd FJ, Nonner D, Bullock MR, et al. Pyroptotic neuronal cell death mediated by the AIM2 inflammasome. J Cereb Blood Flow Metab. 2014;34:621-9.
-
(2014)
J Cereb Blood Flow Metab
, vol.34
, pp. 621-629
-
-
Adamczak, S.E.1
Rivero Vaccari, J.P.2
Dale, G.3
Brand, F.J.4
Nonner, D.5
Bullock, M.R.6
Dahl, G.P.7
Dietrich, W.D.8
Keane, R.W.9
-
11
-
-
84884993094
-
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
-
Fann DY, Lee SY, Manzanero S, Tang SC, Gelderblom M, Chunduri P, et al. Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke. Cell Death Dis. 2013;4, e790.
-
(2013)
Cell Death Dis
, vol.4
-
-
Fann, D.Y.1
Lee, S.Y.2
Manzanero, S.3
Tang, S.C.4
Gelderblom, M.5
Chunduri, P.6
Bernreuther, C.7
Glatzel, M.8
Cheng, Y.L.9
Thundyil, J.10
-
12
-
-
84934989890
-
NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model
-
Tan CC, Zhang JG, Tan MS, Chen H, Meng DW, Jiang T, et al. NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model. J Neuroinflammation. 2015;12:18.
-
(2015)
J Neuroinflammation
, vol.12
, pp. 18
-
-
Tan, C.C.1
Zhang, J.G.2
Tan, M.S.3
Chen, H.4
Meng, D.W.5
Jiang, T.6
Meng, X.F.7
Li, Y.8
Sun, Z.9
Li, M.M.10
-
13
-
-
84927745897
-
Pyroptotic cell death defends against intracellular pathogens
-
Jorgensen I, Miao EA. Pyroptotic cell death defends against intracellular pathogens. Immunol Rev. 2015;265:130-42.
-
(2015)
Immunol Rev
, vol.265
, pp. 130-142
-
-
Jorgensen, I.1
Miao, E.A.2
-
14
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10:417-26.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
16
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol. 2013;13:397-411.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
17
-
-
0030606250
-
Evidence for the neuronal origin of immunoreactive interleukin-1 beta released by rat hypothalamic explants
-
Tringali G, Mancuso C, Mirtella A, Pozzoli G, Parente L, Preziosi P, et al. Evidence for the neuronal origin of immunoreactive interleukin-1 beta released by rat hypothalamic explants. Neurosci Lett. 1996;219:143-6.
-
(1996)
Neurosci Lett
, vol.219
, pp. 143-146
-
-
Tringali, G.1
Mancuso, C.2
Mirtella, A.3
Pozzoli, G.4
Parente, L.5
Preziosi, P.6
Navarra, P.7
-
18
-
-
0031259599
-
The release of immunoreactive interleukin-1 beta from rat hypothalamic explants is modulated by neurotransmitters and corticotropin-releasing hormone
-
Tringali G, Mirtella A, Mancuso C, Guerriero G, Preziosi P, Navarra P. The release of immunoreactive interleukin-1 beta from rat hypothalamic explants is modulated by neurotransmitters and corticotropin-releasing hormone. Pharmacol Res. 1997;36:269-73.
-
(1997)
Pharmacol Res
, vol.36
, pp. 269-273
-
-
Tringali, G.1
Mirtella, A.2
Mancuso, C.3
Guerriero, G.4
Preziosi, P.5
Navarra, P.6
-
19
-
-
61349152312
-
Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice
-
Abulafia DP, de Rivero Vaccari JP, Lozano JD, Lotocki G, Keane RW, Dietrich WD. Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. J Cereb Blood Flow Metab. 2009;29:534-44.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 534-544
-
-
Abulafia, D.P.1
Rivero Vaccari, J.P.2
Lozano, J.D.3
Lotocki, G.4
Keane, R.W.5
Dietrich, W.D.6
-
20
-
-
67649360450
-
Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury
-
de Rivero Vaccari JP, Lotocki G, Alonso OF, Bramlett HM, Dietrich WD, Keane RW. Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury. J Cereb Blood Flow Metab. 2009;29:1251-61.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 1251-1261
-
-
Rivero Vaccari, J.P.1
Lotocki, G.2
Alonso, O.F.3
Bramlett, H.M.4
Dietrich, W.D.5
Keane, R.W.6
-
21
-
-
84956816197
-
Exosome-mediated inflammasome signaling after central nervous system injury
-
de Rivero Vaccari JP, Brand F, 3rd, Adamczak S, Lee SW, Barcena JP, Wang MY, Bullock MR, Dietrich WD, Keane RW. Exosome-mediated inflammasome signaling after central nervous system injury. J Neurochem. 2015;21(Suppl 1):39-48.
-
(2015)
J Neurochem
, vol.21
, pp. 39-48
-
-
de Rivero Vaccari, J.P.1
Brand, F.2
Adamczak, S.3
Lee, S.W.4
Barcena, J.P.5
Wang, M.Y.6
Bullock, M.R.7
Dietrich, W.D.8
Keane, R.W.9
-
22
-
-
78049442406
-
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
-
Paine A, Eiz-Vesper B, Blasczyk R, Immenschuh S. Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem Pharmacol. 2010;80:1895-903.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1895-1903
-
-
Paine, A.1
Eiz-Vesper, B.2
Blasczyk, R.3
Immenschuh, S.4
-
23
-
-
70450137050
-
The heme oxygenase/biliverdin reductase pathway in drug research and development
-
Mancuso C, Barone E. The heme oxygenase/biliverdin reductase pathway in drug research and development. Curr Drug Metab. 2009;10:579-94.
-
(2009)
Curr Drug Metab
, vol.10
, pp. 579-594
-
-
Mancuso, C.1
Barone, E.2
-
24
-
-
0031579657
-
Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element
-
Raju VS, McCoubrey Jr WK, Maines MD. Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element. Biochim Biophys Acta. 1997;1351:89-104.
-
(1997)
Biochim Biophys Acta
, vol.1351
, pp. 89-104
-
-
Raju, V.S.1
McCoubrey, W.K.2
Maines, M.D.3
-
25
-
-
0030923630
-
The heme oxygenase system: a regulator of second messenger gases
-
Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol. 1997;37:517-54.
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 517-554
-
-
Maines, M.D.1
-
26
-
-
0029893772
-
Regulation of human heme oxygenase-1 gene expression under thermal stress
-
Okinaga S, Takahashi K, Takeda K, Yoshizawa M, Fujita H, Sasaki H, et al. Regulation of human heme oxygenase-1 gene expression under thermal stress. Blood. 1996;87:5074-84.
-
(1996)
Blood
, vol.87
, pp. 5074-5084
-
-
Okinaga, S.1
Takahashi, K.2
Takeda, K.3
Yoshizawa, M.4
Fujita, H.5
Sasaki, H.6
Shibahara, S.7
-
27
-
-
0025953506
-
Interleukin-1 and tumour necrosis factor induce hepatic haem oxygenase. Feedback regulation by glucocorticoids
-
Cantoni L, Rossi C, Rizzardini M, Gadina M, Ghezzi P. Interleukin-1 and tumour necrosis factor induce hepatic haem oxygenase. Feedback regulation by glucocorticoids. Biochem J. 1991;279(Pt 3):891-4.
-
(1991)
Biochem J
, vol.279
, pp. 891-894
-
-
Cantoni, L.1
Rossi, C.2
Rizzardini, M.3
Gadina, M.4
Ghezzi, P.5
-
30
-
-
0032748074
-
Inhibition of heme oxygenase in the central nervous system potentiates endotoxin-induced vasopressin release in the rat
-
Mancuso C, Ragazzoni E, Tringali G, Liberale I, Preziosi P, Grossman A, et al. Inhibition of heme oxygenase in the central nervous system potentiates endotoxin-induced vasopressin release in the rat. J Neuroimmunol. 1999;99:189-94.
-
(1999)
J Neuroimmunol
, vol.99
, pp. 189-194
-
-
Mancuso, C.1
Ragazzoni, E.2
Tringali, G.3
Liberale, I.4
Preziosi, P.5
Grossman, A.6
Navarra, P.7
-
31
-
-
0035142856
-
Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms?
-
Panahian N, Maines MD. Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms? J Neurochem. 2001;76:539-54.
-
(2001)
J Neurochem
, vol.76
, pp. 539-554
-
-
Panahian, N.1
Maines, M.D.2
-
32
-
-
58849147989
-
Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1
-
Yamada K, Tanaka N, Nakanishi K, Kamei N, Ishikawa M, Mizuno T, et al. Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1. J Neurosurg Spine. 2008;9:611-20.
-
(2008)
J Neurosurg Spine
, vol.9
, pp. 611-620
-
-
Yamada, K.1
Tanaka, N.2
Nakanishi, K.3
Kamei, N.4
Ishikawa, M.5
Mizuno, T.6
Igarashi, K.7
Ochi, M.8
-
33
-
-
34247495046
-
Heme oxygenase-1 stabilizes the blood-spinal cord barrier and limits oxidative stress and white matter damage in the acutely injured murine spinal cord
-
Lin Y, Vreman HJ, Wong RJ, Tjoa T, Yamauchi T, Noble-Haeusslein LJ. Heme oxygenase-1 stabilizes the blood-spinal cord barrier and limits oxidative stress and white matter damage in the acutely injured murine spinal cord. J Cereb Blood Flow Metab. 2007;27:1010-21.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1010-1021
-
-
Lin, Y.1
Vreman, H.J.2
Wong, R.J.3
Tjoa, T.4
Yamauchi, T.5
Noble-Haeusslein, L.J.6
-
34
-
-
84860517355
-
Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat
-
Hall JC, Priestley JV, Perry VH, Michael-Titus AT. Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat. J Neurochem. 2012;121:738-50.
-
(2012)
J Neurochem
, vol.121
, pp. 738-750
-
-
Hall, J.C.1
Priestley, J.V.2
Perry, V.H.3
Michael-Titus, A.T.4
-
35
-
-
0030971385
-
Neurogenesis in postnatal rat spinal cord: a study in primary culture
-
Kehl LJ, Fairbanks CA, Laughlin TM, Wilcox GL. Neurogenesis in postnatal rat spinal cord: a study in primary culture. Science. 1997;276:586-9.
-
(1997)
Science
, vol.276
, pp. 586-589
-
-
Kehl, L.J.1
Fairbanks, C.A.2
Laughlin, T.M.3
Wilcox, G.L.4
-
36
-
-
1542328959
-
Isolation and culture of motor neurons from the newborn mouse spinal cord
-
Anderson KN, Potter AC, Piccenna LG, Quah AK, Davies KE, Cheema SS. Isolation and culture of motor neurons from the newborn mouse spinal cord. Brain Res Brain Res Protoc. 2004;12:132-6.
-
(2004)
Brain Res Brain Res Protoc
, vol.12
, pp. 132-136
-
-
Anderson, K.N.1
Potter, A.C.2
Piccenna, L.G.3
Quah, A.K.4
Davies, K.E.5
Cheema, S.S.6
-
37
-
-
0028919411
-
A sensitive and reliable locomotor rating scale for open field testing in rats
-
Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma. 1995;12:1-21.
-
(1995)
J Neurotrauma
, vol.12
, pp. 1-21
-
-
Basso, D.M.1
Beattie, M.S.2
Bresnahan, J.C.3
-
39
-
-
84939152599
-
Transcription factor ATF4 induces NLRP1 inflammasome expression during endoplasmic reticulum stress
-
D'Osualdo A, Anania VG, Yu K, Lill JR, Kaufman RJ, Matsuzawa S, et al. Transcription factor ATF4 induces NLRP1 inflammasome expression during endoplasmic reticulum stress. PLoS One. 2015;10, e0130635.
-
(2015)
PLoS One
, vol.10
-
-
D'Osualdo, A.1
Anania, V.G.2
Yu, K.3
Lill, J.R.4
Kaufman, R.J.5
Matsuzawa, S.6
Reed, J.C.7
-
40
-
-
84891745975
-
Endoplasmic reticulum stress response in the rat contusive spinal cord injury model-susceptibility in specific cell types
-
Matsuyama D, Watanabe M, Suyama K, Kuroiwa M, Mochida J. Endoplasmic reticulum stress response in the rat contusive spinal cord injury model-susceptibility in specific cell types. Spinal Cord. 2014;52:9-16.
-
(2014)
Spinal Cord
, vol.52
, pp. 9-16
-
-
Matsuyama, D.1
Watanabe, M.2
Suyama, K.3
Kuroiwa, M.4
Mochida, J.5
-
41
-
-
35648982325
-
Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury
-
Byrnes KR, Stoica BA, Fricke S, Di Giovanni S, Faden AI. Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury. Brain. 2007;130:2977-92.
-
(2007)
Brain
, vol.130
, pp. 2977-2992
-
-
Byrnes, K.R.1
Stoica, B.A.2
Fricke, S.3
Giovanni, S.4
Faden, A.I.5
-
43
-
-
84896546192
-
Nod-like receptor protein 1 inflammasome mediates neuron injury under high glucose
-
Meng XF, Wang XL, Tian XJ, Yang ZH, Chu GP, Zhang J, et al. Nod-like receptor protein 1 inflammasome mediates neuron injury under high glucose. Mol Neurobiol. 2014;49:673-84.
-
(2014)
Mol Neurobiol
, vol.49
, pp. 673-684
-
-
Meng, X.F.1
Wang, X.L.2
Tian, X.J.3
Yang, Z.H.4
Chu, G.P.5
Zhang, J.6
Li, M.7
Shi, J.8
Zhang, C.9
-
44
-
-
67650546999
-
The pannexin 1 channel activates the inflammasome in neurons and astrocytes
-
Silverman WR, de Rivero Vaccari JP, Locovei S, Qiu F, Carlsson SK, Scemes E, et al. The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem. 2009;284:18143-51.
-
(2009)
J Biol Chem
, vol.284
, pp. 18143-18151
-
-
Silverman, W.R.1
Rivero Vaccari, J.P.2
Locovei, S.3
Qiu, F.4
Carlsson, S.K.5
Scemes, E.6
Keane, R.W.7
Dahl, G.8
-
45
-
-
84857530330
-
P2X4 receptors influence inflammasome activation after spinal cord injury
-
de Rivero Vaccari JP, Bastien D, Yurcisin G, Pineau I, Dietrich WD, De Koninck Y, et al. P2X4 receptors influence inflammasome activation after spinal cord injury. J Neurosci. 2012;32:3058-66.
-
(2012)
J Neurosci
, vol.32
, pp. 3058-3066
-
-
Rivero Vaccari, J.P.1
Bastien, D.2
Yurcisin, G.3
Pineau, I.4
Dietrich, W.D.5
Koninck, Y.6
Keane, R.W.7
Lacroix, S.8
-
46
-
-
84929428860
-
Activation and regulation of NLRP3 inflammasome by intrathecal application of SDF-1a in a spinal cord injury model
-
Epub ahead of print
-
Zendedel A, Johann S, Mehrabi S, Joghataei MT, Hassanzadeh G, Kipp M, Beyer C. Activation and regulation of NLRP3 inflammasome by intrathecal application of SDF-1a in a spinal cord injury model. Mol Neurobiol. 2015. Epub ahead of print.
-
(2015)
Mol Neurobiol
-
-
Zendedel, A.1
Johann, S.2
Mehrabi, S.3
Joghataei, M.T.4
Hassanzadeh, G.5
Kipp, M.6
Beyer, C.7
-
47
-
-
77956262043
-
Sensing cytoplasmic danger signals by the inflammasome
-
Alnemri ES. Sensing cytoplasmic danger signals by the inflammasome. J Clin Immunol. 2010;30:512-9.
-
(2010)
J Clin Immunol
, vol.30
, pp. 512-519
-
-
Alnemri, E.S.1
-
49
-
-
84862649049
-
Toll-like receptor (TLR) and inflammasome actions in the central nervous system
-
Hanamsagar R, Hanke ML, Kielian T. Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends Immunol. 2012;33:333-42.
-
(2012)
Trends Immunol
, vol.33
, pp. 333-342
-
-
Hanamsagar, R.1
Hanke, M.L.2
Kielian, T.3
-
50
-
-
84945438257
-
Beta-amyloid, microglia, and the inflammasome in Alzheimer's disease
-
Gold M, El Khoury J. Beta-amyloid, microglia, and the inflammasome in Alzheimer's disease. Semin Immunopathol. 2015;37:607-11.
-
(2015)
Semin Immunopathol
, vol.37
, pp. 607-611
-
-
Gold, M.1
Khoury, J.2
-
51
-
-
84880491311
-
Assessing beta-amyloid-induced NLRP3 inflammasome activation in primary microglia
-
Schnaars M, Beckert H, Halle A. Assessing beta-amyloid-induced NLRP3 inflammasome activation in primary microglia. Methods Mol Biol. 2013;1040:1-8.
-
(2013)
Methods Mol Biol
, vol.1040
, pp. 1-8
-
-
Schnaars, M.1
Beckert, H.2
Halle, A.3
-
52
-
-
4043079197
-
P2X7 receptor inhibition improves recovery after spinal cord injury
-
Wang X, Arcuino G, Takano T, Lin J, Peng WG, Wan P, et al. P2X7 receptor inhibition improves recovery after spinal cord injury. Nat Med. 2004;10:821-7.
-
(2004)
Nat Med
, vol.10
, pp. 821-827
-
-
Wang, X.1
Arcuino, G.2
Takano, T.3
Lin, J.4
Peng, W.G.5
Wan, P.6
Li, P.7
Xu, Q.8
Liu, Q.S.9
Goldman, S.A.10
Nedergaard, M.11
-
53
-
-
68149157440
-
Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury
-
Peng W, Cotrina ML, Han X, Yu H, Bekar L, Blum L, et al. Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proc Natl Acad Sci U S A. 2009;106:12489-93.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12489-12493
-
-
Peng, W.1
Cotrina, M.L.2
Han, X.3
Yu, H.4
Bekar, L.5
Blum, L.6
Takano, T.7
Tian, G.F.8
Goldman, S.A.9
Nedergaard, M.10
-
54
-
-
33750601026
-
The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA
-
Lafon M, Megret F, Lafage M, Prehaud C. The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA. J Mol Neurosci. 2006;29:185-94.
-
(2006)
J Mol Neurosci
, vol.29
, pp. 185-194
-
-
Lafon, M.1
Megret, F.2
Lafage, M.3
Prehaud, C.4
-
55
-
-
35348860696
-
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
-
Tang SC, Arumugam TV, Xu X, Cheng A, Mughal MR, Jo DG, et al. Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci U S A. 2007;104:13798-803.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13798-13803
-
-
Tang, S.C.1
Arumugam, T.V.2
Xu, X.3
Cheng, A.4
Mughal, M.R.5
Jo, D.G.6
Lathia, J.D.7
Siler, D.A.8
Chigurupati, S.9
Ouyang, X.10
-
56
-
-
77953627102
-
Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling
-
Peltier DC, Simms A, Farmer JR, Miller DJ. Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling. J Immunol. 2010;184:7010-21.
-
(2010)
J Immunol
, vol.184
, pp. 7010-7021
-
-
Peltier, D.C.1
Simms, A.2
Farmer, J.R.3
Miller, D.J.4
-
57
-
-
84866870466
-
Neuronal Toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro
-
Leow-Dyke S, Allen C, Denes A, Nilsson O, Maysami S, Bowie AG, et al. Neuronal Toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro. J Neuroinflammation. 2012;9:230.
-
(2012)
J Neuroinflammation
, vol.9
, pp. 230
-
-
Leow-Dyke, S.1
Allen, C.2
Denes, A.3
Nilsson, O.4
Maysami, S.5
Bowie, A.G.6
Rothwell, N.J.7
Pinteaux, E.8
-
58
-
-
4143064639
-
Hemin induces heme oxygenase-1 in spinal cord vasculature and attenuates barrier disruption and neutrophil infiltration in the injured murine spinal cord
-
Yamauchi T, Lin Y, Sharp FR, Noble-Haeusslein LJ. Hemin induces heme oxygenase-1 in spinal cord vasculature and attenuates barrier disruption and neutrophil infiltration in the injured murine spinal cord. J Neurotrauma. 2004;21:1017-30.
-
(2004)
J Neurotrauma
, vol.21
, pp. 1017-1030
-
-
Yamauchi, T.1
Lin, Y.2
Sharp, F.R.3
Noble-Haeusslein, L.J.4
-
59
-
-
79955671381
-
Uptake, metabolism and toxicity of hemin in cultured neurons
-
Dang TN, Robinson SR, Dringen R, Bishop GM. Uptake, metabolism and toxicity of hemin in cultured neurons. Neurochem Int. 2011;58:804-11.
-
(2011)
Neurochem Int
, vol.58
, pp. 804-811
-
-
Dang, T.N.1
Robinson, S.R.2
Dringen, R.3
Bishop, G.M.4
-
60
-
-
0030188587
-
Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury
-
Choi AM, Alam J. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol. 1996;15:9-19.
-
(1996)
Am J Respir Cell Mol Biol
, vol.15
, pp. 9-19
-
-
Choi, A.M.1
Alam, J.2
-
61
-
-
33745839704
-
beta-Carotene and cigarette smoke condensate regulate heme oxygenase-1 and its repressor factor Bach1: relationship with cell growth
-
Palozza P, Serini S, Curro D, Calviello G, Igarashi K, Mancuso C. beta-Carotene and cigarette smoke condensate regulate heme oxygenase-1 and its repressor factor Bach1: relationship with cell growth. Antioxid Redox Signal. 2006;8:1069-80.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1069-1080
-
-
Palozza, P.1
Serini, S.2
Curro, D.3
Calviello, G.4
Igarashi, K.5
Mancuso, C.6
-
62
-
-
33745256807
-
Genetic ablation of the transcription repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice
-
Yano Y, Ozono R, Oishi Y, Kambe M, Yoshizumi M, Ishida T, et al. Genetic ablation of the transcription repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice. Genes Cells. 2006;11:791-803.
-
(2006)
Genes Cells
, vol.11
, pp. 791-803
-
-
Yano, Y.1
Ozono, R.2
Oishi, Y.3
Kambe, M.4
Yoshizumi, M.5
Ishida, T.6
Omura, S.7
Oshima, T.8
Igarashi, K.9
-
63
-
-
59849125389
-
Genetic ablation of transcription repressor Bach1 reduces neural tissue damage and improves locomotor function after spinal cord injury in mice
-
Kanno H, Ozawa H, Dohi Y, Sekiguchi A, Igarashi K, Itoi E. Genetic ablation of transcription repressor Bach1 reduces neural tissue damage and improves locomotor function after spinal cord injury in mice. J Neurotrauma. 2009;26:31-9.
-
(2009)
J Neurotrauma
, vol.26
, pp. 31-39
-
-
Kanno, H.1
Ozawa, H.2
Dohi, Y.3
Sekiguchi, A.4
Igarashi, K.5
Itoi, E.6
-
64
-
-
84876992081
-
Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice
-
Perez-de-Puig I, Martin A, Gorina R, de la Rosa X, Martinez E, Planas AM. Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice. Neuroscience. 2013;243:22-32.
-
(2013)
Neuroscience
, vol.243
, pp. 22-32
-
-
Perez-de-Puig, I.1
Martin, A.2
Gorina, R.3
Rosa, X.4
Martinez, E.5
Planas, A.M.6
-
65
-
-
30344477376
-
The experimental study of hypoxia-inducible factor-1alpha and its target genes in spinal cord injury
-
Xiaowei H, Ninghui Z, Wei X, Yiping T, Linfeng X. The experimental study of hypoxia-inducible factor-1alpha and its target genes in spinal cord injury. Spinal Cord. 2006;44:35-43.
-
(2006)
Spinal Cord
, vol.44
, pp. 35-43
-
-
Xiaowei, H.1
Ninghui, Z.2
Wei, X.3
Yiping, T.4
Linfeng, X.5
-
66
-
-
80054763120
-
Opposite effects of HIF-1alpha and HIF-2alpha on the regulation of IL-8 expression in endothelial cells
-
Florczyk U, Czauderna S, Stachurska A, Tertil M, Nowak W, Kozakowska M, et al. Opposite effects of HIF-1alpha and HIF-2alpha on the regulation of IL-8 expression in endothelial cells. Free Radic Biol Med. 2011;51:1882-92.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1882-1892
-
-
Florczyk, U.1
Czauderna, S.2
Stachurska, A.3
Tertil, M.4
Nowak, W.5
Kozakowska, M.6
Poellinger, L.7
Jozkowicz, A.8
Loboda, A.9
Dulak, J.10
-
67
-
-
66749096539
-
HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells
-
Loboda A, Stachurska A, Florczyk U, Rudnicka D, Jazwa A, Wegrzyn J, et al. HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells. Antioxid Redox Signal. 2009;11:1501-17.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 1501-1517
-
-
Loboda, A.1
Stachurska, A.2
Florczyk, U.3
Rudnicka, D.4
Jazwa, A.5
Wegrzyn, J.6
Kozakowska, M.7
Stalinska, K.8
Poellinger, L.9
Levonen, A.L.10
-
68
-
-
84895511740
-
Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1
-
Luo YP, Jiang L, Kang K, Fei DS, Meng XL, Nan CC, et al. Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1. Int Immunopharmacol. 2014;20:24-32.
-
(2014)
Int Immunopharmacol
, vol.20
, pp. 24-32
-
-
Luo, Y.P.1
Jiang, L.2
Kang, K.3
Fei, D.S.4
Meng, X.L.5
Nan, C.C.6
Pan, S.H.7
Zhao, M.R.8
Zhao, M.Y.9
-
69
-
-
84907456216
-
Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced inflammasome activation in human gingival epithelial cells
-
Li H, Zhou X, Zhang J. Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced inflammasome activation in human gingival epithelial cells. Int J Mol Med. 2014;34:1039-44.
-
(2014)
Int J Mol Med
, vol.34
, pp. 1039-1044
-
-
Li, H.1
Zhou, X.2
Zhang, J.3
-
70
-
-
0033670378
-
Gaseous neuromodulators in the control of neuroendocrine stress axis
-
Navarra P, Dello Russo C, Mancuso C, Preziosi P, Grossman A. Gaseous neuromodulators in the control of neuroendocrine stress axis. Ann N Y Acad Sci. 2000;917:638-46.
-
(2000)
Ann N Y Acad Sci
, vol.917
, pp. 638-646
-
-
Navarra, P.1
Dello Russo, C.2
Mancuso, C.3
Preziosi, P.4
Grossman, A.5
-
71
-
-
84861601576
-
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment
-
Barone E, Di Domenico F, Sultana R, Coccia R, Mancuso C, Perluigi M, et al. Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. Free Radic Biol Med. 2012;52:2292-301.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 2292-2301
-
-
Barone, E.1
Domenico, F.2
Sultana, R.3
Coccia, R.4
Mancuso, C.5
Perluigi, M.6
Butterfield, D.A.7
-
72
-
-
9644288310
-
Protein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo
-
Salinas M, Wang J, Rosa de Sagarra M, Martin D, Rojo AI, Martin-Perez J, et al. Protein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo. FEBS Lett. 2004;578:90-4.
-
(2004)
FEBS Lett
, vol.578
, pp. 90-94
-
-
Salinas, M.1
Wang, J.2
Rosa de Sagarra, M.3
Martin, D.4
Rojo, A.I.5
Martin-Perez, J.6
Ortiz de Montellano, P.R.7
Cuadrado, A.8
-
73
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, et al. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem. 2001;276:20858-65.
-
(2001)
J Biol Chem
, vol.276
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
Stewart, D.4
Choi, M.E.5
Choi, A.M.6
Alam, J.7
-
74
-
-
84936817064
-
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis
-
Dey S, Sayers CM, Verginadis II, Lehman SL, Cheng Y, Cerniglia GJ, et al. ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. J Clin Invest. 2015;125:2592-608.
-
(2015)
J Clin Invest
, vol.125
, pp. 2592-2608
-
-
Dey, S.1
Sayers, C.M.2
Verginadis, I.I.3
Lehman, S.L.4
Cheng, Y.5
Cerniglia, G.J.6
Tuttle, S.W.7
Feldman, M.D.8
Zhang, P.J.9
Fuchs, S.Y.10
-
75
-
-
84907907866
-
Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses
-
Biswas C, Shah N, Muthu M, La P, Fernando AP, Sengupta S, et al. Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses. J Biol Chem. 2014;289:26882-94.
-
(2014)
J Biol Chem
, vol.289
, pp. 26882-26894
-
-
Biswas, C.1
Shah, N.2
Muthu, M.3
La, P.4
Fernando, A.P.5
Sengupta, S.6
Yang, G.7
Dennery, P.A.8
-
76
-
-
84862177395
-
Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas
-
Gandini NA, Fermento ME, Salomon DG, Blasco J, Patel V, Gutkind JS, et al. Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas. Exp Mol Pathol. 2012;93:237-45.
-
(2012)
Exp Mol Pathol
, vol.93
, pp. 237-245
-
-
Gandini, N.A.1
Fermento, M.E.2
Salomon, D.G.3
Blasco, J.4
Patel, V.5
Gutkind, J.S.6
Molinolo, A.A.7
Facchinetti, M.M.8
Curino, A.C.9
-
77
-
-
84876712355
-
Nuclear translocation of heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells
-
Tibullo D, Barbagallo I, Giallongo C, La Cava P, Parrinello N, Vanella L, et al. Nuclear translocation of heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells. Curr Pharm Des. 2013;19:2765-70.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 2765-2770
-
-
Tibullo, D.1
Barbagallo, I.2
Giallongo, C.3
Cava, P.4
Parrinello, N.5
Vanella, L.6
Stagno, F.7
Palumbo, G.A.8
Li Volti, G.9
Raimondo, F.10
-
78
-
-
84882280029
-
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
-
Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, et al. AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death Differ. 2013;20:1149-60.
-
(2013)
Cell Death Differ
, vol.20
, pp. 1149-1160
-
-
Sagulenko, V.1
Thygesen, S.J.2
Sester, D.P.3
Idris, A.4
Cridland, J.A.5
Vajjhala, P.R.6
Roberts, T.L.7
Schroder, K.8
Vince, J.E.9
Hill, J.M.10
-
79
-
-
84889094297
-
Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages
-
Chen HG, Xie KL, Han HZ, Wang WN, Liu DQ, Wang GL, et al. Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. Int J Surg. 2013;11:1060-6.
-
(2013)
Int J Surg
, vol.11
, pp. 1060-1066
-
-
Chen, H.G.1
Xie, K.L.2
Han, H.Z.3
Wang, W.N.4
Liu, D.Q.5
Wang, G.L.6
Yu, Y.H.7
-
80
-
-
0036127426
-
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
-
Lee TS, Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med. 2002;8:240-6.
-
(2002)
Nat Med
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
|