-
1
-
-
84925441813
-
Control of adaptive immunity by the innate immune system
-
Iwasaki A, & Medzhitov R. Control of adaptive immunity by the innate immune system. Nat. Immunol. 16, 343-353 (2015).
-
(2015)
Nat. Immunol
, vol.16
, pp. 343-353
-
-
Iwasaki, A.1
Medzhitov, R.2
-
2
-
-
77951863381
-
Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A (H1N1) disease
-
Morgan O. W, et al. Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A (H1N1) disease. PLoS ONE 5, e9694 (2010).
-
(2010)
PLoS on
, vol.5
, pp. e9694
-
-
Morgan, O.W.1
-
3
-
-
0037425564
-
Mortality associated with influenza and respiratory syncytial virus in the United States
-
Thompson W. W, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 289, 179-186 (2003).
-
(2003)
JAM
, vol.289
, pp. 179-186
-
-
Thompson, W.W.1
-
4
-
-
84862822422
-
Regulating the adaptive immune response to respiratory virus infection
-
Braciale T. J, Sun J, & Kim T. S. Regulating the adaptive immune response to respiratory virus infection. Nat. Rev. Immunol. 12, 295-305 (2012).
-
(2012)
Nat. Rev. Immunol
, vol.12
, pp. 295-305
-
-
Braciale, T.J.1
Sun, J.2
Kim, T.S.3
-
5
-
-
84905722366
-
Lung regeneration: Mechanisms, applications and emerging stem cell populations
-
Kotton D. N, & Morrisey E. E. Lung regeneration: mechanisms, applications and emerging stem cell populations. Nat. Med. 20, 822-832 (2014).
-
(2014)
Nat. Med
, vol.20
, pp. 822-832
-
-
Kotton, D.N.1
Morrisey, E.E.2
-
6
-
-
77956538031
-
Airway basal stem cells: A perspective on their roles in epithelial homeostasis and remodeling
-
Rock J. R, Randell S. H, & Hogan B. L. Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis. Model. Mech. 3, 545-556 (2010).
-
(2010)
Dis. Model. Mech
, vol.3
, pp. 545-556
-
-
Rock, J.R.1
Randell, S.H.2
Hogan, B.L.3
-
7
-
-
77249085745
-
Advances in mucous cell metaplasia: A plug for mucus as a therapeutic focus in chronic airway disease
-
Curran D. R, & Cohn L. Advances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease. Am. J. Respir. Cell Mol. Biol. 42, 268-275 (2010).
-
(2010)
Am. J. Respir. Cell Mol. Biol
, vol.42
, pp. 268-275
-
-
Curran, D.R.1
Cohn, L.2
-
8
-
-
85006707815
-
-
eds Treuting P. M, Dintzis S, Liggitt D.& Frevert C. W.) Ch 9 (Elsevier
-
Suarez C. J, Dintzis S. M, & Frevert C. W. in Comparative Anatomy and Histology: A Mouse and Human Atlasqnq. eds Treuting P. M, Dintzis S, Liggitt D.& Frevert C. W.) Ch. 9 (Elsevier, 2012).
-
(2012)
Comparative Anatomy and Histology: A Mouse and Human Atlas
-
-
Suarez, C.J.1
Dintzis, S.M.2
Frevert, C.W.3
-
9
-
-
84925465211
-
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
-
Perdiguero E. G, et al. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature 518, 547-551 (2015).
-
(2015)
Natur
, vol.518
, pp. 547-551
-
-
Perdiguero, E.G.1
-
10
-
-
84885454468
-
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM CSF
-
Guilliams M, et al. Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM CSF. J. Exp. Med. 210, 1977-1992 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 1977-1992
-
-
Guilliams, M.1
-
11
-
-
84893652705
-
Alveolar macrophages: Plasticity in a tissue-specific context
-
Hussell T, & Bell T. J. Alveolar macrophages: plasticity in a tissue-specific context. Nat. Rev. Immunol. 14, 81-93 (2014).
-
(2014)
Nat. Rev. Immunol
, vol.14
, pp. 81-93
-
-
Hussell, T.1
Bell, T.J.2
-
12
-
-
84896715280
-
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity
-
Westphalen K, et al. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Nature 506, 503-506 (2014).
-
(2014)
Natur
, vol.506
, pp. 503-506
-
-
Westphalen, K.1
-
13
-
-
77951983557
-
Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections
-
Mordstein M, et al. Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections. J. Virol. 84, 5670-5677 (2010).
-
(2010)
J. Virol
, vol.84
, pp. 5670-5677
-
-
Mordstein, M.1
-
14
-
-
60849114033
-
Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells
-
Khaitov M. R, et al. Respiratory virus induction of alpha-, beta- And lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells. Allergy 64, 375-386 (2009).
-
(2009)
Allerg
, vol.64
, pp. 375-386
-
-
Khaitov, M.R.1
-
15
-
-
84904680881
-
Diverse intracellular pathogens activate type III interferon expression from peroxisomes
-
Odendall C, et al. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat. Immunol. 15, 717-726 (2014).
-
(2014)
Nat. Immunol
, vol.15
, pp. 717-726
-
-
Odendall, C.1
-
16
-
-
84924726469
-
The unique regulation and functions of type III interferons in antiviral immunity
-
Odendall C, & Kagan J. C. The unique regulation and functions of type III interferons in antiviral immunity. Curr. Opin. Virol. 12, 47-52 (2015).
-
(2015)
Curr. Opin. Virol
, vol.12
, pp. 47-52
-
-
Odendall, C.1
Kagan, J.C.2
-
17
-
-
84885456710
-
Respiratory virus-induced EGFR activation suppresses IRF1 dependent interferon and antiviral defense in airway epithelium
-
Ueki I. F, et al. Respiratory virus-induced EGFR activation suppresses IRF1 dependent interferon and antiviral defense in airway epithelium. J. Exp. Med. 210, 1929-1936 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 1929-1936
-
-
Ueki, I.F.1
-
18
-
-
84901684203
-
Helicase proteins DHX29 and RIG i cosense cytosolic nucleic acids in the human airway system
-
Sugimoto N, Mitoma H, Kim T, Hanabuchi S, & Liu Y. J. Helicase proteins DHX29 and RIG I cosense cytosolic nucleic acids in the human airway system. Proc. Natl Acad. Sci. USA 111, 7747-7752 (2014).
-
(2014)
Proc. Natl Acad. Sci. US
, vol.111
, pp. 7747-7752
-
-
Sugimoto, N.1
Mitoma, H.2
Kim, T.3
Hanabuchi, S.4
Liu, Y.J.5
-
19
-
-
17644372733
-
IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
-
Liu Y. J. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu. Rev. Immunol. 23, 275-306 (2005).
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 275-306
-
-
Liu, Y.J.1
-
20
-
-
33750338616
-
Plasmacytoid dendritic cells limit viral replication, pulmonary inflammation, and airway hyperresponsiveness in respiratory syncytial virus infection
-
Wang H, Peters N, & Schwarze J. Plasmacytoid dendritic cells limit viral replication, pulmonary inflammation, and airway hyperresponsiveness in respiratory syncytial virus infection. J. Immunol. 177, 6263-6270 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 6263-6270
-
-
Wang, H.1
Peters, N.2
Schwarze, J.3
-
21
-
-
84857099694
-
Plasmacytoid dendritic cells and Toll-like receptor 7 dependent signalling promote efficient protection of mice against highly virulent influenza A virus
-
Kaminski M. M, Ohnemus A, Cornitescu M, & Staeheli P. Plasmacytoid dendritic cells and Toll-like receptor 7 dependent signalling promote efficient protection of mice against highly virulent influenza A virus. J. Gen. Virol. 93, 555-559 (2012).
-
(2012)
J. Gen. Virol
, vol.93
, pp. 555-559
-
-
Kaminski, M.M.1
Ohnemus, A.2
Cornitescu, M.3
Staeheli, P.4
-
22
-
-
77952490197
-
Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes
-
Juarez E, et al. Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes. Respir. Res. 11, 2 (2010).
-
(2010)
Respir. Res
, vol.11
, pp. 2
-
-
Juarez, E.1
-
23
-
-
84937583336
-
Alveolar macrophage-derived type i interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes
-
Goritzka M, et al. Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes. J. Exp. Med. 212, 699-714 (2015).
-
(2015)
J. Exp. Med
, vol.212
, pp. 699-714
-
-
Goritzka, M.1
-
24
-
-
25144515561
-
Divergent roles of IL 23 and IL 12 in host defense against Klebsiella pneumoniae
-
Happel K. I, et al. Divergent roles of IL 23 and IL 12 in host defense against Klebsiella pneumoniae. J. Exp. Med. 202, 761-769 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 761-769
-
-
Happel, K.I.1
-
25
-
-
84881656583
-
The role of lung dendritic cell subsets in immunity to respiratory viruses
-
Neyt K, & Lambrecht B. N. The role of lung dendritic cell subsets in immunity to respiratory viruses. Immunol. Rev. 255, 57-67 (2013).
-
(2013)
Immunol. Rev
, vol.255
, pp. 57-67
-
-
Neyt, K.1
Lambrecht, B.N.2
-
26
-
-
84862893004
-
Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung
-
Thornton E. E, et al. Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung. J. Exp. Med. 209, 1183-1199 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 1183-1199
-
-
Thornton, E.E.1
-
27
-
-
0035177431
-
Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
-
Vermaelen K. Y, Carro-Muino I, Lambrecht B. N, & Pauwels R. A. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J. Exp. Med. 193, 51-60 (2001).
-
(2001)
J. Exp. Med
, vol.193
, pp. 51-60
-
-
Vermaelen, K.Y.1
Carro-Muino, I.2
Lambrecht, B.N.3
Pauwels, R.A.4
-
28
-
-
84878167904
-
IRF4 transcription-factor-dependent CD103+ CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation
-
Persson E. K, et al. IRF4 transcription-factor-dependent CD103+ CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation. Immunity 38, 958-969 (2013).
-
(2013)
Immunit
, vol.38
, pp. 958-969
-
-
Persson, E.K.1
-
29
-
-
29144434113
-
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
-
Bafica A, et al. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J. Exp. Med. 202, 1715-1724 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1715-1724
-
-
Bafica, A.1
-
30
-
-
84875080678
-
Complement mediated signaling on pulmonary CD103+ dendritic cells is critical for their migratory function in response to influenza infection
-
Kandasamy M, et al. Complement mediated signaling on pulmonary CD103+ dendritic cells is critical for their migratory function in response to influenza infection. PLoS Pathog. 9, e1003115 (2013).
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003115
-
-
Kandasamy, M.1
-
31
-
-
79955121049
-
Microbiota regulates immune defense against respiratory tract influenza A virus infection
-
Ichinohe T, et al. Microbiota regulates immune defense against respiratory tract influenza A virus infection. Proc. Natl Acad. Sci. USA 108, 5354-5359 (2011).
-
(2011)
Proc. Natl Acad. Sci. US
, vol.108
, pp. 5354-5359
-
-
Ichinohe, T.1
-
32
-
-
84920547918
-
Response of host inflammasomes to viral infection
-
Chen I. Y, & Ichinohe T. Response of host inflammasomes to viral infection. Trends Microbiol. 23, 55-63 (2015).
-
(2015)
Trends Microbiol
, vol.23
, pp. 55-63
-
-
Chen, I.Y.1
Ichinohe, T.2
-
33
-
-
84875542536
-
Recognition of bacteria by inflammasomes
-
von Moltke J, Ayres J. S, Kofoed E. M, Chavarria-Smith J, & Vance R. E. Recognition of bacteria by inflammasomes. Annu. Rev. Immunol. 31, 73-106 (2013).
-
(2013)
Annu. Rev. Immunol
, vol.31
, pp. 73-106
-
-
Von Moltke, J.1
Ayres, J.S.2
Kofoed, E.M.3
Chavarria-Smith, J.4
Vance, R.E.5
-
34
-
-
64149087970
-
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
-
Hammad H, et al. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat. Med. 15, 410-416 (2009).
-
(2009)
Nat. Med
, vol.15
, pp. 410-416
-
-
Hammad, H.1
-
35
-
-
61549104474
-
Innate immune responses of airway epithelium to house dust mite are mediated through β-glucan-dependent pathways
-
Nathan A. T, Peterson E. A, Chakir J, & Wills-Karp M. Innate immune responses of airway epithelium to house dust mite are mediated through β-glucan-dependent pathways. J. Allergy Clin. Immunol. 123, 612-618 (2009).
-
(2009)
J. Allergy Clin. Immunol
, vol.123
, pp. 612-618
-
-
Nathan, A.T.1
Peterson, E.A.2
Chakir, J.3
Wills-Karp, M.4
-
36
-
-
84876913029
-
Protective and pathological roles of mast cells and basophils
-
Voehringer D. Protective and pathological roles of mast cells and basophils. Nat. Rev. Immunol. 13, 362-375 (2013).
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 362-375
-
-
Voehringer, D.1
-
37
-
-
33847134006
-
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells
-
Allakhverdi Z, et al. Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J. Exp. Med. 204, 253-258 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 253-258
-
-
Allakhverdi, Z.1
-
38
-
-
53749093767
-
The IL 1 like cytokine IL 33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: A novel 'alarmin'
-
Moussion C, Ortega N, & Girard J. P. The IL 1 like cytokine IL 33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'. PLoS ONE 3, e3331 (2008).
-
(2008)
PLoS on
, vol.3
, pp. e3331
-
-
Moussion, C.1
Ortega, N.2
Girard, J.P.3
-
39
-
-
84883537459
-
Long-Term IL 33 producing epithelial progenitor cells in chronic obstructive lung disease
-
Byers D. E, et al. Long-Term IL 33 producing epithelial progenitor cells in chronic obstructive lung disease. J. Clin. Invest. 123, 3967-3982 (2013).
-
(2013)
J. Clin. Invest
, vol.123
, pp. 3967-3982
-
-
Byers, D.E.1
-
40
-
-
84862860830
-
A critical role of IL 33 in experimental allergic rhinitis
-
e111
-
Haenuki Y, et al. A critical role of IL 33 in experimental allergic rhinitis. J. Allergy Clin. Immunol. 130, 184-194.e111 (2012).
-
(2012)
J. Allergy Clin Immunol
, vol.130
, pp. 184-194
-
-
Haenuki, Y.1
-
41
-
-
84905968184
-
Alternaria-derived serine protease activity drives IL 33 mediated asthma exacerbations
-
e586
-
Snelgrove R. J, et al. Alternaria-derived serine protease activity drives IL 33 mediated asthma exacerbations. J. Allergy Clin. Immunol. 134, 583-592.e586 (2014).
-
(2014)
J. Allergy Clin. Immunol
, vol.134
, pp. 583-592
-
-
Snelgrove, R.J.1
-
42
-
-
68249137289
-
Suppression of interleukin 33 bioactivity through proteolysis by apoptotic caspases
-
Lhi A. U, et al. Suppression of interleukin 33 bioactivity through proteolysis by apoptotic caspases. Immunity 31, 84-98 (2009).
-
(2009)
Immunit
, vol.31
, pp. 84-98
-
-
Lhi, A.U.1
-
43
-
-
84857484469
-
Interleukin 33 as a mechanically responsive cytokine secreted by living cells
-
Kakkar R, Hei H, Dobner S, & Lee R. T. Interleukin 33 as a mechanically responsive cytokine secreted by living cells. J. Biol. Chem. 287, 6941-6948 (2012).
-
(2012)
J. Biol. Chem
, vol.287
, pp. 6941-6948
-
-
Kakkar, R.1
Hei, H.2
Dobner, S.3
Lee, R.T.4
-
44
-
-
70249093313
-
Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-Activated receptor 2
-
Kouzaki H, O?Grady S. M, Lawrence C. B, & Kita H. Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-Activated receptor 2. J. Immunol. 183, 1427-1434 (2009).
-
(2009)
J. Immunol
, vol.183
, pp. 1427-1434
-
-
Kouzaki, H.1
O'Grady, S.M.2
Lawrence, C.B.3
Kita, H.4
-
45
-
-
84884905739
-
IL 33 is more potent than IL 25 in provoking IL 13 producing nuocytes (type 2 innate lymphoid cells) and airway contraction
-
Barlow J. L, et al. IL 33 is more potent than IL 25 in provoking IL 13 producing nuocytes (type 2 innate lymphoid cells) and airway contraction. J. Allergy Clin. Immunol. 132, 933-941 (2013).
-
(2013)
J. Allergy Clin. Immunol
, vol.132
, pp. 933-941
-
-
Barlow, J.L.1
-
46
-
-
33748064320
-
IL 25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice
-
Tamachi T, et al. IL 25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice. J. Allergy Clin. Immunol. 118, 606-614 (2006).
-
(2006)
J. Allergy Clin. Immunol
, vol.118
, pp. 606-614
-
-
Tamachi, T.1
-
47
-
-
84953284110
-
Group 2 innate lymphoid cells utilize the IRF4-IL 9 module to coordinate epithelial cell maintenance of lung homeostasis
-
Mohapatra A, et al. Group 2 innate lymphoid cells utilize the IRF4-IL 9 module to coordinate epithelial cell maintenance of lung homeostasis. Mucosal Immunol. 9, 275-286 (2016).
-
(2016)
Mucosal Immunol
, vol.9
, pp. 275-286
-
-
Mohapatra, A.1
-
48
-
-
84947423751
-
Pulmonary epithelial cell-derived cytokine TGF β1 is a critical cofactor for enhanced innate lymphoid cell function
-
Denney L, et al. Pulmonary epithelial cell-derived cytokine TGF β1 is a critical cofactor for enhanced innate lymphoid cell function. Immunity 43, 945-958 (2015).
-
(2015)
Immunit
, vol.43
, pp. 945-958
-
-
Denney, L.1
-
49
-
-
84923357083
-
Homeostasis, inflammation, and disease susceptibility
-
Kotas M. E, & Medzhitov R. Homeostasis, inflammation, and disease susceptibility. Cell 160, 816-827 (2015).
-
(2015)
Cel
, vol.160
, pp. 816-827
-
-
Kotas, M.E.1
Medzhitov, R.2
-
50
-
-
84954064749
-
Characterization and quantification of innate lymphoid cell subsets in human lung
-
De Grove K. C, et al. Characterization and quantification of innate lymphoid cell subsets in human lung. PLoS ONE 11, e0145961 (2016).
-
(2016)
PLoS on
, vol.11
, pp. e0145961
-
-
De Grove, K.C.1
-
51
-
-
84904335796
-
Activation of type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection
-
Van Maele L, et al. Activation of type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection. J. Infect. Dis. 210, 493-503 (2014).
-
(2014)
J. Infect. Dis
, vol.210
, pp. 493-503
-
-
Van Maele, L.1
-
52
-
-
42449085370
-
Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease development
-
Pribul P. K, et al. Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease development. J. Virol. 82, 4441-4448 (2008).
-
(2008)
J. Virol
, vol.82
, pp. 4441-4448
-
-
Pribul, P.K.1
-
53
-
-
84876431327
-
NK cells exacerbate the pathology of influenza virus infection in mice
-
Zhou G, Juang S. W. W, & Kane K. P. NK cells exacerbate the pathology of influenza virus infection in mice. Eur. J. Immunol. 43, 929-938 (2013).
-
(2013)
Eur. J. Immunol
, vol.43
, pp. 929-938
-
-
Zhou, G.1
Juang, S.W.W.2
Kane, K.P.3
-
54
-
-
84867658823
-
IL 22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection
-
Kumar P, Thakar M. S, Ouyang W, & Malarkannan S. IL 22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection. Mucosal Immunol. 6, 69-82 (2013).
-
(2013)
Mucosal Immunol
, vol.6
, pp. 69-82
-
-
Kumar, P.1
Thakar, M.S.2
Ouyang, W.3
Malarkannan, S.4
-
55
-
-
49649123906
-
Diverse cytokine production by NKT cell subsets and identification of an IL 17 producing CD4-NK1.1- NKT cell population
-
Coquet J. M, et al. Diverse cytokine production by NKT cell subsets and identification of an IL 17 producing CD4-NK1.1- NKT cell population. Proc. Natl Acad. Sci. USA 105, 11287-11292 (2008).
-
(2008)
Proc. Natl Acad. Sci. US
, vol.105
, pp. 11287-11292
-
-
Coquet, J.M.1
-
56
-
-
79958248405
-
Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
-
Brigl M, et al. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. J. Exp. Med. 208, 1163-1177 (2011).
-
(2011)
J. Exp. Med
, vol.208
, pp. 1163-1177
-
-
Brigl, M.1
-
57
-
-
84858587977
-
Interleukin 22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: Potential role in protection against lung epithelial damages
-
Paget C, et al. Interleukin 22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. J. Biol. Chem. 287, 8816-8829 (2012).
-
(2012)
J. Biol. Chem
, vol.287
, pp. 8816-8829
-
-
Paget, C.1
-
58
-
-
68649088121
-
Interleukin 1 and IL 23 induce innate IL 17 production from γ T cells, amplifying Th17 responses and autoimmunity
-
Sutton C. E, et al. Interleukin 1 and IL 23 induce innate IL 17 production from γ T cells, amplifying Th17 responses and autoimmunity. Immunity 31, 331-341 (2009).
-
(2009)
Immunit
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
-
59
-
-
33749138039
-
IL 17 production is dominated by γ T cells rather than CD4 T cells during Mycobacterium tuberculosis infection
-
Lockhart E, Green A. M, & Flynn J. L. IL 17 production is dominated by γ T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J. Immunol. 177, 4662-4669 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 4662-4669
-
-
Lockhart, E.1
Green, A.M.2
Flynn, J.L.3
-
60
-
-
0029031029
-
Activation of gamma delta T cells for production of IFN-gamma is mediated by bacteria via macrophage-derived cytokines IL 1 and IL 12
-
Skeen M. J, & Ziegler H. K. Activation of gamma delta T cells for production of IFN-gamma is mediated by bacteria via macrophage-derived cytokines IL 1 and IL 12. J. Immunol. 154, 5832-5841 (1995).
-
(1995)
J. Immunol
, vol.154
, pp. 5832-5841
-
-
Skeen, M.J.1
Ziegler, H.K.2
-
61
-
-
82755192260
-
Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection
-
Teijaro J. R, et al. Cutting edge: tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection. J. Immunol. 187, 5510-5514 (2011).
-
(2011)
J. Immunol
, vol.187
, pp. 5510-5514
-
-
Teijaro, J.R.1
-
62
-
-
80054889051
-
Human IL 25 and IL 33 responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
-
Mjfsberg J. M, et al. Human IL 25 and IL 33 responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat. Immunol. 12, 1055-1062 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 1055-1062
-
-
Mjfsberg, J.M.1
-
63
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type 2 immunity
-
Neill D. R, et al. Nuocytes represent a new innate effector leukocyte that mediates type 2 immunity. Nature 464, 1367-1370 (2010).
-
(2010)
Natur
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
-
64
-
-
84858775590
-
Lung natural helper cells are a critical source of Th2 cell-Type cytokines in protease allergen-induced airway inflammation
-
Halim T. Y, Krauss R. H, Sun A. C, & Takei F. Lung natural helper cells are a critical source of Th2 cell-Type cytokines in protease allergen-induced airway inflammation. Immunity 36, 451-463 (2012).
-
(2012)
Immunit
, vol.36
, pp. 451-463
-
-
Halim, T.Y.1
Krauss, R.H.2
Sun, A.C.3
Takei, F.4
-
65
-
-
84922857734
-
IL 25 responsive, lineage-negative KLRG1hi cells are multipotential inflammatory type 2 innate lymphoid cells
-
Huang Y, et al. IL 25 responsive, lineage-negative KLRG1hi cells are multipotential inflammatory type 2 innate lymphoid cells. Nat. Immunol. 16, 161-169 (2015).
-
(2015)
Nat. Immunol
, vol.16
, pp. 161-169
-
-
Huang, Y.1
-
66
-
-
84886630206
-
IL 25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells
-
Saenz S. A, et al. IL 25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J. Exp. Med. 210, 1823-1837 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 1823-1837
-
-
Saenz, S.A.1
-
67
-
-
84964300561
-
IL 1 is a critical regulator of group 2 innate lymphoid cell function and plasticity
-
Ohne Y, et al. IL 1 is a critical regulator of group 2 innate lymphoid cell function and plasticity. Nat. Immunol. 17, 646-655 (2016).
-
(2016)
Nat. Immunol
, vol.17
, pp. 646-655
-
-
Ohne, Y.1
-
68
-
-
84890852091
-
IL 9 mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation
-
Turner J. E, et al. IL 9 mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J. Exp. Med. 210, 2951-2965 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 2951-2965
-
-
Turner, J.E.1
-
69
-
-
58149289887
-
A novel subset of mouse NKT cells bearing the IL 17 receptor B responds to IL 25 and contributes to airway hyperreactivity
-
Terashima A, et al. A novel subset of mouse NKT cells bearing the IL 17 receptor B responds to IL 25 and contributes to airway hyperreactivity. J. Exp. Med. 205, 2727-2733 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 2727-2733
-
-
Terashima, A.1
-
70
-
-
0037911660
-
Essential role of qNKT cells producing IL 4 and IL 13 in the development of allergen-induced airway hyperreactivity
-
Akbari O, et al. Essential role of NKT cells producing IL 4 and IL 13 in the development of allergen-induced airway hyperreactivity. Nat. Med. 9, 582-588 (2003).
-
(2003)
Nat. Med
, vol.9
, pp. 582-588
-
-
Akbari, O.1
-
71
-
-
39549106479
-
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL 17
-
Pichavant M, et al. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL 17. J. Exp. Med. 205, 385-393 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 385-393
-
-
Pichavant, M.1
-
72
-
-
36249027661
-
Differential role of thymic stromal lymphopoietin in the induction of airway hyperreactivity and Th2 immune response in antigen-induced asthma with respect to natural killer T cell function
-
Nagata Y, Kamijuku H, Taniguchi M, Ziegler S, & Seino K. I. Differential role of thymic stromal lymphopoietin in the induction of airway hyperreactivity and Th2 immune response in antigen-induced asthma with respect to natural killer T cell function. Int. Arch. Allergy Immunol. 144, 305-314 (2007).
-
(2007)
Int. Arch. Allergy Immunol
, vol.144
, pp. 305-314
-
-
Nagata, Y.1
Kamijuku, H.2
Taniguchi, M.3
Ziegler, S.4
Seino, K.I.5
-
73
-
-
48449089903
-
IL 33 amplifies both Th1 and Th2 type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells
-
Smithgall M. D, et al. IL 33 amplifies both Th1 and Th2 type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int. Immunol. 20, 1019-1030 (2008).
-
(2008)
Int. Immunol
, vol.20
, pp. 1019-1030
-
-
Smithgall, M.D.1
-
74
-
-
80555139637
-
Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation
-
Scanlon S. T, et al. Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation. J. Exp. Med. 208, 2113-2124 (2011).
-
(2011)
J. Exp. Med
, vol.208
, pp. 2113-2124
-
-
Scanlon, S.T.1
-
75
-
-
84928584195
-
The development and in vivo function of T helper 9 cells
-
Kaplan M. H, Hufford M. M, & Olson M. R. The development and in vivo function of T helper 9 cells. Nat. Rev. Immunol. 15, 295-307 (2015).
-
(2015)
Nat. Rev. Immunol
, vol.15
, pp. 295-307
-
-
Kaplan, M.H.1
Hufford, M.M.2
Olson, M.R.3
-
76
-
-
84874241774
-
Interleukin 9 is required for allergic airway inflammation mediated by the cytokine TSLP
-
Yao W, et al. Interleukin 9 is required for allergic airway inflammation mediated by the cytokine TSLP. Immunity 38, 360-372 (2013).
-
(2013)
Immunit
, vol.38
, pp. 360-372
-
-
Yao, W.1
-
77
-
-
79953327120
-
IL 9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways
-
Kearley J, et al. IL 9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways. Am. J. Respir. Crit. Care Med. 183, 865-875 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med
, vol.183
, pp. 865-875
-
-
Kearley, J.1
-
78
-
-
84940996934
-
Interleukin 21 producing CD4+ Tcells promote Type 2 immunity to house dust mites
-
Coquet J. M, et al. Interleukin 21 producing CD4+ Tcells promote Type 2 immunity to house dust mites. Immunity 43, 318-330 (2015).
-
(2015)
Immunit
, vol.43
, pp. 318-330
-
-
Coquet, J.M.1
-
79
-
-
76949102494
-
Regulation of IL 9 expression by IL 25 signaling
-
Angkasekwinai P, Chang S. H, Thapa M, Watarai H, & Dong C. Regulation of IL 9 expression by IL 25 signaling. Nat. Immunol. 11, 250-256 (2010).
-
(2010)
Nat. Immunol
, vol.11
, pp. 250-256
-
-
Angkasekwinai, P.1
Chang, S.H.2
Thapa, M.3
Watarai, H.4
Dong, C.5
-
80
-
-
33846515975
-
Induction of IL 4 expression in CD4+ T cells by thymic stromal lymphopoietin
-
Omori M, & Ziegler S. Induction of IL 4 expression in CD4+ T cells by thymic stromal lymphopoietin. J. Immunol. 178, 1396-1404 (2007).
-
(2007)
J. Immunol
, vol.178
, pp. 1396-1404
-
-
Omori, M.1
Ziegler, S.2
-
81
-
-
27744446058
-
IL 33, an interleukin 1 like cytokine that signals via the IL 1 receptor-related protein ST2 and induces T helper type 2 associated cytokines
-
Schmitz J, et al. IL 33, an interleukin 1 like cytokine that signals via the IL 1 receptor-related protein ST2 and induces T helper type 2 associated cytokines. Immunity 23, 479-490 (2005).
-
(2005)
Immunit
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
-
82
-
-
84886900071
-
Human CD1c+ dendritic cells secrete high levels of IL 12 and potently prime cytotoxic T cell responses
-
Nizzoli G, et al. Human CD1c+ dendritic cells secrete high levels of IL 12 and potently prime cytotoxic T cell responses. Blood 122, 932-942 (2013).
-
(2013)
Bloo
, vol.122
, pp. 932-942
-
-
Nizzoli, G.1
-
83
-
-
40049098958
-
IL 22 mediates mucosal host defense against Gram-negative bacterial pneumonia
-
Aujla S. J, et al. IL 22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med. 14, 275-281 (2008).
-
(2008)
Nat. Med
, vol.14
, pp. 275-281
-
-
Aujla, S.J.1
-
84
-
-
65249145291
-
TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection
-
Aldridge J. R. Jr, et al. TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc. Natl Acad. Sci. USA 106, 5306-5311 (2009).
-
(2009)
Proc. Natl Acad. Sci. US
, vol.106
, pp. 5306-5311
-
-
Aldridge, J.R.1
-
85
-
-
0037443571
-
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: Role of the CCL2-CCR2 axis
-
Maus U. A, et al. Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis. J. Immunol. 170, 3273-3278 (2003).
-
(2003)
J. Immunol
, vol.170
, pp. 3273-3278
-
-
Maus, U.A.1
-
86
-
-
84895754889
-
Inflammatory monocytes orchestrate innate antifungal immunity in the lung
-
Espinosa V, et al. Inflammatory monocytes orchestrate innate antifungal immunity in the lung. PLoS Pathog. 10, e1003940 (2014).
-
(2014)
PLoS Pathog
, vol.10
, pp. e1003940
-
-
Espinosa, V.1
-
87
-
-
42149083307
-
CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality
-
Lin K. L, Suzuki Y, Nakano H, Ramsburg E, & Gunn M. D. CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality. J. Immunol. 180, 2562-2572 (2008).
-
(2008)
J. Immunol
, vol.180
, pp. 2562-2572
-
-
Lin, K.L.1
Suzuki, Y.2
Nakano, H.3
Ramsburg, E.4
Gunn, M.D.5
-
88
-
-
35748957798
-
Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages
-
Landsman L, & Jung S. Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J. Immunol. 179, 3488-3494 (2007).
-
(2007)
J. Immunol
, vol.179
, pp. 3488-3494
-
-
Landsman, L.1
Jung, S.2
-
89
-
-
78149258267
-
In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation
-
Kreisel D, et al. In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation. Proc. Natl Acad. Sci. USA 107, 18073-18078 (2010).
-
(2010)
Proc. Natl Acad. Sci. US
, vol.107
, pp. 18073-18078
-
-
Kreisel, D.1
-
90
-
-
33847759560
-
Interleukin 12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection
-
Sun K, Salmon S. L, Lotz S. A, & Metzger D. W. Interleukin 12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection. Infect. Immun. 75, 1196-1202 (2007).
-
(2007)
Infect. Immun
, vol.75
, pp. 1196-1202
-
-
Sun, K.1
Salmon, S.L.2
Lotz, S.A.3
Metzger, D.W.4
-
91
-
-
84861217128
-
Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced Toll-like receptor signaling
-
Bradley L. M, Douglass M. F, Chatterjee D, Akira S, & Baaten B. J. Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced Toll-like receptor signaling. PLoS Pathog. 8, e1002641 (2012).
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002641
-
-
Bradley, L.M.1
Douglass, M.F.2
Chatterjee, D.3
Akira, S.4
Baaten, B.J.5
-
92
-
-
84891505072
-
NETosis: How vital is it?
-
Yipp B. G, & Kubes P. NETosis: how vital is it?. Blood 122, 2784-2794 (2013).
-
(2013)
Bloo
, vol.122
, pp. 2784-2794
-
-
Yipp, B.G.1
Kubes, P.2
-
93
-
-
84964798222
-
Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease
-
Pillai P. S, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science 352, 463-466 (2016).
-
(2016)
Scienc
, vol.352
, pp. 463-466
-
-
Pillai, P.S.1
-
94
-
-
77954161132
-
Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA
-
Bruns S, et al. Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA. PLoS Pathog. 6, e1000873 (2010).
-
(2010)
PLoS Pathog
, vol.6
, pp. e1000873
-
-
Bruns, S.1
-
95
-
-
0033104696
-
Effects of Th2 cytokines on chemokine expression in the lung: IL 13 potently induces eotaxin expression by airway epithelial cells
-
Li L, et al. Effects of Th2 cytokines on chemokine expression in the lung: IL 13 potently induces eotaxin expression by airway epithelial cells. J. Immunol. 162, 2477-2487 (1999).
-
(1999)
J. Immunol
, vol.162
, pp. 2477-2487
-
-
Li, L.1
-
96
-
-
0036344597
-
Direct effects of interleukin 13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman D. A, et al. Direct effects of interleukin 13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat. Med. 8, 885-889 (2002).
-
(2002)
Nat. Med
, vol.8
, pp. 885-889
-
-
Kuperman, D.A.1
-
97
-
-
85027948313
-
Innate lymphoid cells promote lung-Tissue homeostasis after infection with influenza virus
-
Monticelli L. A, et al. Innate lymphoid cells promote lung-Tissue homeostasis after infection with influenza virus. Nat. Immunol. 12, 1045-1054 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 1045-1054
-
-
Monticelli, L.A.1
-
98
-
-
0034769498
-
IL 13 induces eosinophil recruitment into the lung by an IL 5- and eotaxin-dependent mechanism
-
Pope S. M, et al. IL 13 induces eosinophil recruitment into the lung by an IL 5- And eotaxin-dependent mechanism. J. Allergy Clin. Immunol. 108, 594-601 (2001).
-
(2001)
J. Allergy Clin. Immunol
, vol.108
, pp. 594-601
-
-
Pope, S.M.1
-
99
-
-
77956633109
-
Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils
-
Wong C. K, Hu S, Cheung P. F. Y, & Lam C. W. K. Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils. Am. J. Respir. Cell Mol. Biol. 43, 305-315 (2010).
-
(2010)
Am. J. Respir. Cell Mol. Biol
, vol.43
, pp. 305-315
-
-
Wong, C.K.1
Hu, S.2
Cheung, P.F.Y.3
Lam, C.W.K.4
-
100
-
-
84871482550
-
Eosinophils: Changing perspectives in health and disease
-
Rosenberg H. F, Dyer K. D, & Foster P. S. Eosinophils: changing perspectives in health and disease. Nat. Rev. Immunol. 13, 9-22 (2013).
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 9-22
-
-
Rosenberg, H.F.1
Dyer, K.D.2
Foster, P.S.3
-
101
-
-
84872420593
-
Basophils are recruited to inflamed lungs and exacerbate memory Th2 responses in mice and humans
-
Wakahara K, et al. Basophils are recruited to inflamed lungs and exacerbate memory Th2 responses in mice and humans. Allergy 68, 180-189 (2013).
-
(2013)
Allerg
, vol.68
, pp. 180-189
-
-
Wakahara, K.1
-
102
-
-
84900397775
-
Basophil-derived interleukin 4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation
-
Motomura Y, et al. Basophil-derived interleukin 4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. Immunity 40, 758-771 (2014).
-
(2014)
Immunit
, vol.40
, pp. 758-771
-
-
Motomura, Y.1
-
103
-
-
84924205634
-
Autoimmunity: Basophils in autoimmune and inflammatory diseases
-
Sharma M, & Bayry J. Autoimmunity: basophils in autoimmune and inflammatory diseases. Nat. Rev. Rheumatol. 11, 129-131 (2015).
-
(2015)
Nat. Rev. Rheumatol
, vol.11
, pp. 129-131
-
-
Sharma, M.1
Bayry, J.2
-
104
-
-
80052582016
-
TSLP promotes interleukin 3 independent basophil haematopoiesis and type 2 inflammation
-
Siracusa M. C, et al. TSLP promotes interleukin 3 independent basophil haematopoiesis and type 2 inflammation. Nature 477, 229-233 (2011).
-
(2011)
Natur
, vol.477
, pp. 229-233
-
-
Siracusa, M.C.1
-
105
-
-
0032485483
-
Role for interleukin 3 in mast-cell and basophil development and in immunity to parasites
-
Lantz C. S, et al. Role for interleukin 3 in mast-cell and basophil development and in immunity to parasites. Nature 392, 90-93 (1998).
-
(1998)
Natur
, vol.392
, pp. 90-93
-
-
Lantz, C.S.1
-
106
-
-
73949111782
-
Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells
-
Ohnmacht C, & Voehringer D. Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells. J. Immunol. 184, 344-350 (2010).
-
(2010)
J. Immunol
, vol.184
, pp. 344-350
-
-
Ohnmacht, C.1
Voehringer, D.2
-
107
-
-
84891705895
-
Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin 33 (IL 33) and limits danger-induced inflammation
-
Roy A, et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin 33 (IL 33) and limits danger-induced inflammation. J. Biol. Chem. 289, 237-250 (2014).
-
(2014)
J. Biol. Chem
, vol.289
, pp. 237-250
-
-
Roy, A.1
-
108
-
-
84937697152
-
An interleukin 33-mast cell- interleukin 2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers
-
Morita H, et al. An interleukin 33-mast cell- interleukin 2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers. Immunity 43, 175-186 (2015).
-
(2015)
Immunit
, vol.43
, pp. 175-186
-
-
Morita, H.1
-
109
-
-
84908541933
-
Central domain of IL 33 is cleaved by mast cell proteases for potent activation of group 2 innate lymphoid cells
-
Lefrançais E, et al. Central domain of IL 33 is cleaved by mast cell proteases for potent activation of group 2 innate lymphoid cells. Proc. Natl Acad. Sci. USA 111, 15502-15507 (2014).
-
(2014)
Proc. Natl Acad. Sci. US
, vol.111
, pp. 15502-15507
-
-
Lefrançais, E.1
-
110
-
-
84857538593
-
Disease tolerance as a defense strategy
-
Medzhitov R, Schneider D. S, & Soares M. P. Disease tolerance as a defense strategy. Science 335, 936-941 (2012).
-
(2012)
Scienc
, vol.335
, pp. 936-941
-
-
Medzhitov, R.1
Schneider, D.S.2
Soares, M.P.3
-
111
-
-
84878756188
-
Role of tissue protection in lethal respiratory viral-bacterial coinfection
-
Jamieson A. M, et al. Role of tissue protection in lethal respiratory viral-bacterial coinfection. Science 340, 1230-1234 (2013).
-
(2013)
Scienc
, vol.340
, pp. 1230-1234
-
-
Jamieson, A.M.1
-
112
-
-
84926489979
-
Yersinia pestis activates both IL 1β and IL 1 receptor antagonist to modulate lung inflammation during pneumonic plague
-
Sivaraman V, et al. Yersinia pestis activates both IL 1β and IL 1 receptor antagonist to modulate lung inflammation during pneumonic plague. PLoS Pathog. 11, e1004688 (2015).
-
(2015)
PLoS Pathog
, vol.11
, pp. e1004688
-
-
Sivaraman, V.1
-
113
-
-
84892739389
-
Cell death by pyroptosis drives CD4 T cell depletion in HIV 1 infection
-
Doitsh G, et al. Cell death by pyroptosis drives CD4 T cell depletion in HIV 1 infection. Nature 505, 509-514 (2014).
-
(2014)
Natur
, vol.505
, pp. 509-514
-
-
Doitsh, G.1
-
114
-
-
84986253848
-
Opposing effects of fasting metabolism on tissue tolerance in bacterial and viral inflammation
-
e1512
-
Wang A, et al. Opposing effects of fasting metabolism on tissue tolerance in bacterial and viral inflammation. Cell 166, 1512-1525.e1512 (2016).
-
(2016)
Cel
, vol.166
, pp. 1512-1525
-
-
Wang, A.1
-
115
-
-
84922236335
-
Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells
-
Foxman E. F, et al. Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proc. Natl Acad. Sci. USA 112, 827-832 (2015).
-
(2015)
Proc. Natl Acad. Sci. US
, vol.112
, pp. 827-832
-
-
Foxman, E.F.1
-
116
-
-
84979642364
-
Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature
-
Foxman E. F, Storer J. A, Vanaja K, Levchenko A, & Iwasaki A. Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. Proc. Natl Acad. Sci. USA 113, 8496-8501 (2016).
-
(2016)
Proc. Natl Acad. Sci. US
, vol.113
, pp. 8496-8501
-
-
Foxman, E.F.1
Storer, J.A.2
Vanaja, K.3
Levchenko, A.4
Iwasaki, A.5
-
117
-
-
77956646453
-
Reduced expression of IRF7 in nasal epithelial cells from smokers after infection with influenza
-
Jaspers I, et al. Reduced expression of IRF7 in nasal epithelial cells from smokers after infection with influenza. Am. J. Respir. Cell Mol. Biol. 43, 368-375 (2010).
-
(2010)
Am. J. Respir. Cell Mol. Biol
, vol.43
, pp. 368-375
-
-
Jaspers, I.1
-
118
-
-
40749087232
-
Cigarette smoke suppresses type i interferon-mediated antiviral immunity in lung fibroblast and epithelial cells
-
Bauer C. M, et al. Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells. J. Interferon Cytokine Res. 28, 167-179 (2008).
-
(2008)
J. Interferon Cytokine Res
, vol.28
, pp. 167-179
-
-
Bauer, C.M.1
-
119
-
-
84924981783
-
Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type i interleukin 33 dependent response to infection
-
Kearley J, et al. Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin 33 dependent response to infection. Immunity 42, 566-579 (2015).
-
(2015)
Immunit
, vol.42
, pp. 566-579
-
-
Kearley, J.1
-
120
-
-
84887354679
-
The aging lung
-
Lowery E. M, Brubaker A. L, Kuhlmann E, & Kovacs E. J. The aging lung. Clin. Interv. Aging 8, 1489-1496 (2013).
-
(2013)
Clin. Interv. Agin
, vol.8
, pp. 1489-1496
-
-
Lowery, E.M.1
Brubaker, A.L.2
Kuhlmann, E.3
Kovacs, E.J.4
-
122
-
-
84055190787
-
Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice
-
Zhao J, Zhao J, Legge K, & Perlman S. Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. J. Clin. Invest. 121, 4921-4930 (2011).
-
(2011)
J. Clin. Invest
, vol.121
, pp. 4921-4930
-
-
Zhao, J.1
Zhao, J.2
Legge, K.3
Perlman, S.4
-
123
-
-
80053386591
-
Natural killer cell function is altered during the primary response of aged mice to influenza infection
-
Beli E, et al. Natural killer cell function is altered during the primary response of aged mice to influenza infection. Mech. Ageing Dev. 132, 503-510 (2011).
-
(2011)
Mech. Ageing Dev
, vol.132
, pp. 503-510
-
-
Beli, E.1
-
124
-
-
33845920088
-
Advanced age exacerbates the pulmonary inflammatory response after lipopolysaccharide exposure
-
Gomez C. R, et al. Advanced age exacerbates the pulmonary inflammatory response after lipopolysaccharide exposure. Crit. Care Med. 35, 246-251 (2007).
-
(2007)
Crit. Care Med
, vol.35
, pp. 246-251
-
-
Gomez, C.R.1
-
125
-
-
84879966712
-
A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection
-
Brandes M, Klauschen F, Kuchen S, & Germain R. N. A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection. Cel 154 197-212 (2013).
-
(2013)
Cell
, vol.154
, pp. 197-212
-
-
Brandes, M.1
Klauschen, F.2
Kuchen, S.3
Germain, R.N.4
-
126
-
-
0344065387
-
Prospective study of body mass index, weight change, and risk of adult-onset asthma in women
-
Camargo C. A, Weiss S. T, Zhang S, Willett W. C, & Speizer F. E. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch. Intern. Med. 159, 2582-2588 (1999).
-
(1999)
Arch. Intern. Med
, vol.159
, pp. 2582-2588
-
-
Camargo, C.A.1
Weiss, S.T.2
Zhang, S.3
Willett, W.C.4
Speizer, F.E.5
-
127
-
-
84959568311
-
Diet-induced obesity alters myeloid cell populations in na?ve and injured lung
-
Manicone A. M, Gong K, Johnston L. K, & Giannandrea M. Diet-induced obesity alters myeloid cell populations in na?ve and injured lung. Respir. Res. 17, 1-11 (2016).
-
(2016)
Respir. Res
, vol.17
, pp. 1-11
-
-
Manicone, A.M.1
Gong, K.2
Johnston, L.K.3
Giannandrea, M.4
-
128
-
-
84891889644
-
Interleukin 17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-Associated airway hyperreactivity
-
Kim H. Y, et al. Interleukin 17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-Associated airway hyperreactivity. Nat. Med. 20, 54-61 (2014).
-
(2014)
Nat. Med
, vol.20
, pp. 54-61
-
-
Kim, H.Y.1
-
129
-
-
84988916072
-
A comparative study of lung host defense in murine obesity models: Insights into neutrophil function
-
Ubags N. D, et al. A comparative study of lung host defense in murine obesity models: insights into neutrophil function. Am. J. Respir. Cell Mol. Biol. 55, 188-200 (2016).
-
(2016)
Am. J Respir. Cell Mol. Biol
, vol.55
, pp. 188-200
-
-
Ubags, N.D.1
-
130
-
-
84555186972
-
Impaired wound healing predisposes obese mice to severe influenza virus infection
-
O?Brien K. B, et al. Impaired wound healing predisposes obese mice to severe influenza virus infection. J. Infect. Dis. 205, 252-261 (2012).
-
(2012)
J. Infect. Dis
, vol.205
, pp. 252-261
-
-
O'Brien, K.B.1
-
131
-
-
84870786888
-
Decreased interferon α and interferon β production in obesity and expression of suppressor of cytokine signaling
-
Teran-Cabanillas E, Montalvo-Corral M, Caire- Juvera G, Moya-Camarena S. Y, & Hernαndez J. Decreased interferon α and interferon β production in obesity and expression of suppressor of cytokine signaling. Nutrition 29, 207-212 (2013).
-
(2013)
Nutritio
, vol.29
, pp. 207-212
-
-
Teran-Cabanillas, E.1
Montalvo-Corral, M.2
Caire-Juvera, G.3
Moya-Camarena, S.Y.4
Hernndez, J.5
-
132
-
-
79957571971
-
IL 33 activated dendritic cells are critical for allergic airway inflammation
-
Besnard A. G, et al. IL 33 activated dendritic cells are critical for allergic airway inflammation. Eur. J. Immunol. 41, 1675-1686 (2011).
-
(2011)
Eur. J. Immunol
, vol.41
, pp. 1675-1686
-
-
Besnard, A.G.1
-
133
-
-
0036301998
-
Human epithelial cells trigger dendritic cell-mediated allergic inflammation by producing TSLP
-
Soumelis V, et al. Human epithelial cells trigger dendritic cell-mediated allergic inflammation by producing TSLP. Nat. Immunol. 3, 673-680 (2002).
-
(2002)
Nat. Immunol
, vol.3
, pp. 673-680
-
-
Soumelis, V.1
-
134
-
-
84896343916
-
Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
-
Halim T. Y. F, et al. Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation. Immunity 40, 425-435 (2014).
-
(2014)
Immunit
, vol.40
, pp. 425-435
-
-
Halim, T.Y.F.1
-
135
-
-
84874254531
-
Conventional and monocyte-derived CD11b+ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen
-
Plantinga M, et al. Conventional and monocyte-derived CD11b+ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 38, 322-335 (2013).
-
(2013)
Immunit
, vol.38
, pp. 322-335
-
-
Plantinga, M.1
-
136
-
-
84885831956
-
CD301b+ dermal dendritic cells drive T helper 2 cell-mediated immunity
-
Kumamoto Y, et al. CD301b+ dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity 39, 733-743 (2013).
-
(2013)
Immunit
, vol.39
, pp. 733-743
-
-
Kumamoto, Y.1
-
137
-
-
69549135695
-
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function
-
Massacand J. C, et al. Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function. Proc. Natl Acad. Sci. USA 106, 13968-13973 (2009).
-
(2009)
Proc. Natl Acad. Sci. US
, vol.106
, pp. 13968-13973
-
-
Massacand, J.C.1
-
138
-
-
59049100417
-
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
-
Trompette A, et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 457, 585-588 (2009).
-
(2009)
Natur
, vol.457
, pp. 585-588
-
-
Trompette, A.1
-
139
-
-
33748509524
-
The major glycoproteinq allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro
-
Shreffler W. G, et al. The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro. J. Immunol. 177, 3677-3685 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 3677-3685
-
-
Shreffler, W.G.1
-
140
-
-
77954524570
-
The ABCs of rhinoviruses, wheezing, and asthma
-
Gern J. E. The ABCs of rhinoviruses, wheezing, and asthma. J. Virol. 84, 7418-7426 (2010).
-
(2010)
J. Virol
, vol.84
, pp. 7418-7426
-
-
Gern, J.E.1
-
141
-
-
17144403499
-
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
-
Wark P. A, et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J. Exp. Med. 201, 937-947 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 937-947
-
-
Wark, P.A.1
-
142
-
-
33748446393
-
Role of deficient type III interferon- production in asthma exacerbations
-
Contoli M, et al. Role of deficient type III interferon-? production in asthma exacerbations. Nat. Med. 12, 1023-1026 (2006).
-
(2006)
Nat. Med
, vol.12
, pp. 1023-1026
-
-
Contoli, M.1
-
143
-
-
84893914123
-
Rhinovirus-induced interferon production is not deficient in well controlled asthma
-
Sykes A, et al. Rhinovirus-induced interferon production is not deficient in well controlled asthma. Thorax 69, 240-246 (2014).
-
(2014)
Thora
, vol.69
, pp. 240-246
-
-
Sykes, A.1
-
144
-
-
84879400685
-
Impaired innate interferon induction in severe therapy resistant atopic asthmatic children
-
Edwards M. R, et al. Impaired innate interferon induction in severe therapy resistant atopic asthmatic children. Mucosal Immunol. 6, 797-806 (2013).
-
(2013)
Mucosal Immunol
, vol.6
, pp. 797-806
-
-
Edwards, M.R.1
-
145
-
-
84870291769
-
Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma
-
Baraldo S, et al. Deficient antiviral immune responses in childhood: distinct roles of atopy and asthma. J. Allergy Clin. Immunol. 130, 1307-1314 (2012).
-
(2012)
J. Allergy Clin. Immunol
, vol.130
, pp. 1307-1314
-
-
Baraldo, S.1
-
146
-
-
84929513174
-
The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development
-
Teo S. M, et al. The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development. Cell Host Microbe 17, 704-715 (2015).
-
(2015)
Cell Host Microb
, vol.17
, pp. 704-715
-
-
Teo, S.M.1
-
147
-
-
84961656295
-
Visualization of immediate immune responses to pioneer metastatic cells in the lung
-
Headley M. B, et al. Visualization of immediate immune responses to pioneer metastatic cells in the lung. Nature 531, 513-517 (2016).
-
(2016)
Natur
, vol.531
, pp. 513-517
-
-
Headley, M.B.1
-
148
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-Tumour metastasis
-
Qian B. Z, et al. CCL2 recruits inflammatory monocytes to facilitate breast-Tumour metastasis. Nature 475, 222-225 (2011).
-
(2011)
Natur
, vol.475
, pp. 222-225
-
-
Qian, B.Z.1
-
149
-
-
85010299095
-
Neutrophils suppress intraluminal NK mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
-
Spiegel A, et al. Neutrophils suppress intraluminal NK mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells. Cancer Discov. 6, 630-649 (2016).
-
(2016)
Cancer Discov
, vol.6
, pp. 630-649
-
-
Spiegel, A.1
-
150
-
-
31544469201
-
Matrix metalloproteinase 9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment
-
Acuff H. B, Carter K. J, Fingleton B, Gorden D. L, & Matrisian L. M. Matrix metalloproteinase 9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment. Cancer Res. 66, 259-266 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 259-266
-
-
Acuff, H.B.1
Carter, K.J.2
Fingleton, B.3
Gorden, D.L.4
Matrisian, L.M.5
-
151
-
-
84929646029
-
Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs
-
Sharma S. K, et al. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J. Immunol. 194, 5529-5538 (2015).
-
(2015)
J. Immunol
, vol.194
, pp. 5529-5538
-
-
Sharma, S.K.1
-
152
-
-
0032965275
-
Number and proliferation of clara cells in normal human airway epithelium
-
Boers J. E, Ambergen A. W, & Thunnissen F. B. Number and proliferation of clara cells in normal human airway epithelium. Am. J. Respir. Crit. Care Med. 159, 1585-1591 (1999).
-
(1999)
Am. J. Respir. Crit. Care Med
, vol.159
, pp. 1585-1591
-
-
Boers, J.E.1
Ambergen, A.W.2
Thunnissen, F.B.3
|