Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 21, 2014, Pages 7747-7752

  Sugimoto, Naoshi ^a   Mitoma, Hiroki ^a,b   Kim, Taeil ^a   Hanabuchi, Shino ^a   Liu, Yong Jun ^a,c  

^a BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^b KYUSHU UNIVERSITY HOSPITAL   (Japan)

^c MEDIMMUNE   (United States)

Author keywords

Airway infection; Cytosolic sensor

Indexed keywords

BETA INTERFERON; CYTOSOLIC NUCLEIC ACID; DEAH BOX POLYPEPTIDE 29; DNA; HELICASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 6; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; NUCLEIC ACID; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AIRWAY; ARTICLE; BRONCHUS; EPITHELIUM CELL; FIBROBLAST; GENE SILENCING; HUMAN; HUMAN CELL; MACROPHAGE; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRACHEA;

AIRWAY INFECTION; CYTOSOLIC SENSOR;

CYTOSOL; DEAD-BOX RNA HELICASES; DNA, COMPLEMENTARY; HUMANS; IMMUNITY, INNATE; NUCLEIC ACIDS; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY MUCOSA; RNA HELICASES; RNA INTERFERENCE; SEQUENCE ANALYSIS, DNA; VIRUS DISEASES; VIRUSES;

EID: 84901684203     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1400139111     Document Type: Article

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