Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 3, 2015, Pages 827-832

  Foxman, Ellen F ^a   Storer, James A ^a,c   Fitzgerald, Megan E ^b   Wasik, Bethany R ^b,d   Hou, Lin ^b   Zhao, Hongyu ^b   Turner, Paul E ^b   Pyle, Anna Marie ^b   Iwasaki, Akiko ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c Jounce Therapeutics   (United States)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

Airway; Common cold; Innate immunity; Rhinovirus; RIG I

Indexed keywords

INTERFERON; INTERFERON TYPE III; RECOMBINANT INTERFERON; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

AIRWAY; ANIMAL CELL; ARTICLE; GENE EXPRESSION; GENETIC DISORDER; HUMAN RHINOVIRUS; INNATE IMMUNITY; LUNG ALVEOLUS EPITHELIUM CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RHINOVIRUS INFECTION; TEMPERATURE; TEMPERATURE DEPENDENCE; VIROGENESIS; VIRUS GENE; VIRUS REPLICATION; ANIMAL; IMMUNOLOGY; MOLECULAR GENETICS; PHYSIOLOGY; RHINOVIRUS; TRACHEA; VIROLOGY;

HUMAN RHINOVIRUS SP.; RHINOVIRUS;

ANIMALS; IMMUNITY, INNATE; MICE; MOLECULAR SEQUENCE DATA; RHINOVIRUS; TEMPERATURE; TRACHEA; VIRUS REPLICATION;

EID: 84922236335     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1411030112     Document Type: Article

References (44)

1. World Health Organization (2007) Global Surveillance, Prevention and Control of Chronic Respiratory Diseases: A Comprehensive Approach (WHO, Geneva).
2. Gern JE (2010) The ABCs of rhinoviruses, wheezing, and asthma. J Virol 84(15): 7418-7426.
3. Jacobs SE, Lamson DM, St George K, Walsh TJ (2013) Human rhinoviruses. Clin Microbiol Rev 26(1):135-162.
4. Tyrrell DA, Parsons R (1960) Some virus isolations from common colds. III. Cytopathic effects in tissue cultures. Lancet 1(7118):239-242.
5. Turner RB, Couch RB (2007) in Fields Virology, eds Knipe DM, Howley PM (Lippincott Williams & Wilkins, Philadelphia), Vol 1, pp 895-909.
6. Stott EJ, Heath GF (1970) Factors affecting the growth of rhinovirus 2 in suspension cultures of L132 cells. J Gen Virol 6(1):15-24.
7. Yin FH, Knight E, Jr (1972) In vivo and in vitro synthesis of human rhinovirus type 2 ribonucleic acid. J Virol 10(1):93-98.
8. Yin FH, Lomax NB (1983) Host range mutants of human rhinovirus in which nonstructural proteins are altered. J Virol 48(2):410-418.
9. Tuthill TJ, et al. (2003) Mouse respiratory epithelial cells support efficient replication of human rhinovirus. J Gen Virol 84(Pt 10):2829-2836.
10. Rasmussen AL, Racaniello VR (2011) Selection of rhinovirus 1A variants adapted for growth in mouse lung epithelial cells. Virology 420(2):82-88.
11. Harris JR, Racaniello VR (2005) Amino acid changes in proteins 2B and 3A mediate rhinovirus type 39 growth in mouse cells. J Virol 79(9):5363-5373.
12. Harris JR, Racaniello VR (2003) Changes in rhinovirus protein 2C allow efficient replication in mouse cells. J Virol 77(8):4773-4780.
13. Cakebread JA, et al. (2011) Exogenous IFN-beta has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus. J Allergy Clin Immunol 127(5):1148-1154, e9.
14. Brockman-Schneider RA, Amineva SP, Bulat MV, Gern JE (2008) Serial culture of murine primary airway epithelial cells and ex vivo replication of human rhinoviruses. J Immunol Methods 339(2):264-269.
15. Killington RA, Stott EJ, Lee D (1977) The effect of temperature on the synthesis of rhinovirus type 2 RNA. J Gen Virol 36(3):403-411.
16. Contoli M, et al. (2006) Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 12(9):1023-1026.
17. Rotbart HA (2000) Antiviral therapy for enteroviruses and rhinoviruses. Antivir Chem Chemother 11(4):261-271.
18. Becker TM, et al. (2013) Exogenous interferons reduce rhinovirus replication and alter airway inflammatory responses. Ann Allergy Asthma Immunol 111(5):397-401.
19. Wang Q, et al. (2009) Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol 183(11):6989-6997.
20. Slater L, et al. (2010) Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog 6(11):e1001178.
21. Wang Q, et al. (2011) MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness. PLoS Pathog 7(5):e1002070.
22. Stetson DB, Medzhitov R (2006) Type I interferons in host defense. Immunity 25(3): 373-381.
23. Kato H, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441(7089):101-105.
24. Gitlin L, et al. (2006) Essential role of mda-5 in type I IFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci USA 103(22):8459-8464.
25. Kohlway A, Luo D, Rawling DC, Ding SC, Pyle AM (2013) Defining the functional determinants for RNA surveillance by RIG-I. EMBO Rep 14(9):772-779.
26. Rawling DC, Kohlway AS, Luo D, Ding SC, Pyle AM (2015) The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domain. Nucleic Acids Res 42(18):11601-11611.
27. Schneider WM, Chevillotte MD, Rice CM (2014) Interferon-stimulated genes: A complex web of host defenses. Annu Rev Immunol 32:513-545.
28. Ivashkiv LB, Donlin LT (2014) Regulation of type I interferon responses. Nat Rev Immunol 14(1):36-49.
29. Mourtzoukou EG, Falagas ME (2007) Exposure to cold and respiratory tract infections. Int J Tuberc Lung Dis 11(9):938-943.
30. Papadopoulos NG, et al. (2000) Rhinoviruses infect the lower airways. J Infect Dis 181(6):1875-1884.
31. Gern JE, Galagan DM, Jarjour NN, Dick EC, Busse WW (1997) Detection of rhinovirus RNA in lower airway cells during experimentally induced infection. Am J Respir Crit Care Med 155(3):1159-1161.
32. Wos M, et al. (2008) The presence of rhinovirus in lower airways of patients with bronchial asthma. Am J Respir Crit Care Med 177(10):1082-1089.
33. McFadden ER, Jr, et al. (1985) Thermal mapping of the airways in humans. J Appl Physiol (1985) 58(2):564-570.
34. Papadopoulos NG, Sanderson G, Hunter J, Johnston SL (1999) Rhinoviruses replicate effectively at lower airway temperatures. J Med Virol 58(1):100-104.
35. Ashraf S, Brockman-Schneider R, Bochkov YA, Pasic TR, Gern JE (2013) Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells. Virology 436(1):143-149.
36. Tapparel C, et al. (2013) Growth and characterization of different human rhinovirus C types in three-dimensional human airway epithelia reconstituted in vitro. Virology 446(1-2):1-8.
37. Wark PA, et al. (2005) Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 201(6):937-947.
38. Sykes A, et al. (2014) Rhinovirus-induced interferon production is not deficient in well controlled asthma. Thorax 69(3):240-246.
39. Fiala M, Kenny GE (1966) Enhancement of rhinovirus plaque formation in human heteroploid cell cultures by magnesium and calcium. J Bacteriol 92(6):1710-1715.
40. Trapnell C, Pachter L, Salzberg SL (2009) TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 25(9):1105-1111.
41. Li H, Durbin R (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25(14):1754-1760.
42. Trapnell C, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 28(5):511-515.
43. Huang W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4(1):44-57.
44. Huang DW, Sherman BT, Lempicki RA (2009) Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37(1):1-13.