The unique regulation and functions of type III interferons in antiviral immunity

Current Opinion in Virology

Volumn 12, Issue , 2015, Pages 47-52

  Odendall, Charlotte ^a   Kagan, Jonathan C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERFERON RECEPTOR; ANTIVIRUS AGENT;

ANTIVIRAL ACTIVITY; ARTICLE; INNATE IMMUNITY; INTERFERON PRODUCTION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; GENETICS; HUMAN; IMMUNOLOGY; MOUSE; PATHOGENICITY; VIRUS; VIRUS INFECTION;

ANIMALS; ANTIVIRAL AGENTS; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; INTERFERONS; MICE; SIGNAL TRANSDUCTION; VIRUS DISEASES; VIRUSES;

EID: 84924726469     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2015.02.003     Document Type: Review

References (43)

1. E. Dixit, S. Boulant, Y. Zhang, A.S.Y. Lee, C. Odendall, B. Shum, N. Hacohen, Z.J. Chen, S.P. Whelan, and M. Fransen Peroxisomes are signaling platforms for antiviral innate immunity Cell 141 2010 668 681
2. A. Stirnweiss, A. Ksienzyk, K. Klages, U. Rand, M. Grashoff, H. Hauser, and A. Kroger IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction J Immunol 184 2010 5179 5185
3. J.A. Pulit-Penaloza, S.V. Scherbik, and M.A. Brinton Type 1 IFN-independent activation of a subset of interferon stimulated genes in West Nile virus Eg101-infected mouse cells Virology 425 2012 82 94
4. R.S. Noyce, S.E. Collins, and K.L. Mossman Identification of a novel pathway essential for the immediate-early, interferon-independent antiviral response to enveloped virions J Virol 80 2006 226 235
5. R.S. Noyce, K. Taylor, M. Ciechonska, S.E. Collins, R. Duncan, and K.L. Mossman Membrane perturbation elicits an IRF3-dependent, interferon-independent antiviral response J Virol 85 2011 10926 10931
6. D.C. Peltier, H.M. Lazear, J.R. Farmer, M.S. Diamond, and D.J. Miller Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by Western equine encephalitis virus capsid J Virol 87 2013 1821 1833
7. S.V. Kotenko, G. Gallagher, V.V. Baurin, A. Lewis-Antes, M. Shen, N.K. Shah, J.A. Langer, F. Sheikh, H. Dickensheets, and R.P. Donnelly IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex Nat Immunol 4 2003 69 77
8. P. Sheppard, W. Kindsvogel, W. Xu, K. Henderson, S. Schlutsmeyer, T.E. Whitmore, R. Kuestner, U. Garrigues, C. Birks, and J. Roraback IL-28, IL-29 and their class II cytokine receptor IL-28R Nat Immunol 4 2002 63 68
9. L. Prokunina-Olsson, B. Muchmore, W. Tang, R.M. Pfeiffer, H. Park, H. Dickensheets, D. Hergott, P. Porter-Gill, A. Mumy, and I. Kohaar A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus Nat Genet 45 2013 164 171
10. A. Lasfar, A. Lewis-Antes, S.V. Smirnov, S. Anantha, W. Abushahba, B. Tian, K. Reuhl, H. Dickensheets, F. Sheikh, and R.P. Donnelly Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma Cancer Res 66 2006 4468 4477
11. C. Sommereyns, S. Paul, P. Staeheli, and T. Michiels IFN-lambda (IFN-λ) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo PLoS Pathog 4 2008 e1000017
12. L. Dumoutier, D. Lejeune, S. Hor, H. Fickenscher, and J.-C. Renauld Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3 Biochem J 370 2003 391 396
13. L. Dumoutier, A. Tounsi, T. Michiels, C. Sommereyns, S.V. Kotenko, and J.-C. Renauld Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling J Biol Chem 279 2004 32269 32274
14. G.R. Stark, I.M. Kerr, B.R.G. Williams, R.H. Silverman, and R.D. Schreiber How cells respond to interferons Annu Rev Biochem 67 1998 227 264
15. C. Odendall, E. Dixit, F. Stavru, H. Bierne, K.M. Franz, A.F. Durbin, S. Boulant, L. Gehrke, P. Cossart, and J.C. Kagan Diverse intracellular pathogens activate type III interferon expression from peroxisomes Nat Immunol 2014 10.1038/ni.2915
16. S.-J. Lee, W.-J. Kim, and S.-K. Moon Role of the p38 MAPK signaling pathway in mediating interleukin-28A-induced migration of UMUC-3 cells Int J Mol Med 2012 10.3892/ijmm.2012.1064
17. J. Diegelmann, F. Beigel, K. Zitzmann, A. Kaul, B. Göke, C.J. Auernhammer, R. Bartenschlager, H.M. Diepolder, and S. Brand Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus PLoS ONE 5 2010 e15200
18. S.E. Doyle, H. Schreckhise, K. Khuu-Duong, K. Henderson, R. Rosler, H. Storey, L. Yao, H. Liu, F. Barahmand-pour, and P. Sivakumar Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes Hepatology 44 2006 896 906
19. Z. Zhou, O.J. Hamming, N. Ank, S.R. Paludan, A.L. Nielsen, and R. Hartmann Type III interferon (IFN) induces a Type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases J Virol 81 2007 7749 7758
20. M. Mordstein, E. Neugebauer, V. Ditt, B. Jessen, T. Rieger, V. Falcone, F. Sorgeloos, S. Ehl, D. Mayer, and G. Kochs Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections J Virol 84 2010 5670 5677
21. T. Okabayashi, T. Kojima, T. Masaki, and S. Yokota Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells Virus Res 160 2011 360 366
22. J. Pott, T. Mahlakõiv, M. Mordstein, C.U. Duerr, T. Michiels, S. Stockinger, P. Staeheli, and M.W. Hornef IFN-lambda determines the intestinal epithelial antiviral host defense Proc Natl Acad Sci U S A 108 2011 7944 7949
23. N.A. Jewell, T. Cline, S.E. Mertz, S.V. Smirnov, E. Flano, C. Schindler, J.L. Grieves, R.K. Durbin, S.V. Kotenko, and J.E. Durbin Interferon-{lambda} is the predominant interferon induced by influenza A virus infection in vivo J Virol 2010 10.1128/JVI. 01703-09
24. S.M. Mäkelä, P. Osterlund, and I. Julkunen TLR ligands induce synergistic interferon-β and interferon-λ1 gene expression in human monocyte-derived dendritic cells Mol Immunol 48 2011 505 515
25. J. Sirén, J. Pirhonen, I. Julkunen, and S. Matikainen IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29 J Immunol 174 2005 1932 1937
26. E.M. Coccia, M. Severa, E. Giacomini, D. Monneron, M.E. Remoli, I. Julkunen, M. Cella, R. Lande, and G. Uzé Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells Eur J Immunol 34 2004 796 805
27. N. Ank, M. Iversen, and C. Bartholdy An important role for type III interferon (IFN-λ/IL-28) in TLR-induced antiviral activity J Immunol 180 2008 2474 2485
28. H. Sui, M. Zhou, Q. Chen, H.C. Lane, and T. Imamichi siRNA enhances DNA-mediated interferon lambda-1 response through crosstalk between RIG-I and IFI16 signalling pathway Nucleic Acids Res 42 2014 583 598
29. J. Li, S. Hu, L. Zhou, L. Ye, X. Wang, J. Ho, and W.Z. Ho Interferon lambda inhibits herpes simplex virus type I infection of human astrocytes and neurons Glia 59 2011 58 67
30. J. Melchjorsen, J. Sirén, I. Julkunen, S.R. Paludan, and S. Matikainen Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3 J Gen Virol 87 2006 1099 1108
31. M. Okamoto, H. Oshiumi, M. Azuma, N. Kato, M. Matsumoto, and T. Seya IPS-1 is essential for type III IFN production by hepatocytes and dendritic cells in response to hepatitis C virus infection J Immunol 192 2014 2770 2777
32. K. Onoguchi, M. Yoneyama, A. Takemura, S. Akira, T. Taniguchi, H. Namiki, and T. Fujita Viral infections activate types I and III interferon genes through a common mechanism J Biol Chem 282 2007 7576 7581
33. P. Osterlund, V. Veckman, J. Siren, K.M. Klucher, J. Hiscott, S. Matikainen, and I. Julkunen Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells J Virol 79 2005 9608 9617
34. R.B. Seth, L. Sun, C.-K. Ea, and Z.J. Chen Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3 Cell 122 2005 669 682
35. S.M. Horner, H.M. Liu, H.S. Park, J. Briley, and M. Gale Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus Proc Natl Acad Sci U S A 108 2011 14590 14595
36. D. Thanos, and T. Maniatis Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome Cell 83 1995 1091 1100
37. D. Panne The enhanceosome Curr Opin Struct Biol 18 2008 236 242
38. L.F. Reis, H. Ruffner, G. Stark, M. Aguet, and C. Weissmann Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes EMBO J 13 1994 4798
39. I.F. Ueki, G. Min-Oo, A. Kalinowski, E. Ballon-Landa, L.L. Lanier, J.A. Nadel, and J.L. Koff Respiratory virus-induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium J Exp Med 210 2013 1929 1936
40. R. Siegel, J. Eskdale, and G. Gallagher Regulation of IFN-λ1 promoter activity (IFN-λ1/IL-29) in human airway epithelial cells J Immunol 187 2011 5636 5644
41. S.J.P. Thomson, F.G. Goh, H. Banks, T. Krausgruber, S.V. Kotenko, B.M.J. Foxwell, and I.A. Udalova The role of transposable elements in the regulation of IFN-lambda1 gene expression Proc Natl Acad Sci U S A 106 2009 11564 11569
42. E.M. Sandberg, X. Ma, K. He, S.J. Frank, D.A. Ostrov, and P.P. Sayeski Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of Jak2 tyrosine kinase autophophorylation J Med Chem 48 2005 2526 2533
43. D. Miller, K. Klucher, and J. Freeman Interferon lambda as a potential new therapeutic for hepatitis C Ann N Y Acad Sci 1182 2009 80 87