Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection

Immunity

Volumn 42, Issue 3, 2015, Pages 566-579

  Kearley, Jennifer ^a   Silver, Jonathan S ^a   Sanden, Caroline ^b   Liu, Zheng ^a   Berlin, Aaron A ^a   White, Natalie ^a   Mori, Michiko ^b   Pham, Tuyet Hang ^a   Ward, Christine K ^a   Criner, Gerard J ^c   Marchetti, Nathaniel ^c   Mustelin, Tomas ^a   Erjefalt, Jonas S ^b   Kolbeck, Roland ^a   Humbles, Alison A ^a  

^a MEDIMMUNE   (United States)

^b LUND UNIVERSITY   (Sweden)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; GAMMA INTERFERON; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 33; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; IL1RL1 PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR; INTERLEUKIN-33, MOUSE; SMOKE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; FLOW CYTOMETRY; IMMUNE SYSTEM; INFLAMMATION; INFLUENZA VIRUS A; LUNG ALVEOLUS CELL; LUNG BIOPSY; LYMPHOID CELL; MACROPHAGE; MICROENVIRONMENT; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SMOKING; VIRUS INFECTION; ADVERSE EFFECTS; ANIMAL; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; LUNG; LYMPHOCYTE; ORTHOMYXOVIRIDAE INFECTIONS; PATHOLOGY; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; SMOKE; TOBACCO; TRANSGENIC MOUSE; WEIGHT REDUCTION;

ANIMALS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS; INTERLEUKINS; KILLER CELLS, NATURAL; LUNG; LYMPHOCYTES; MACROPHAGES; MICE, TRANSGENIC; ORTHOMYXOVIRIDAE INFECTIONS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, INTERLEUKIN; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; SMOKE; TOBACCO; WEIGHT LOSS;

EID: 84924981783     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.02.011     Document Type: Article

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