Autoimmunity: Basophils in autoimmune and inflammatory diseases

Nature Reviews Rheumatology

Volumn 11, Issue 3, 2015, Pages 129-131

  Sharma, Meenu ^a   Bayry, Jagadeesh ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; COMPLEMENT COMPONENT C3; FC RECEPTOR IIB; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 4; L SELECTIN; THYMIC STROMAL LYMPHOPOIETIN; TOLL LIKE RECEPTOR;

ANTIBODY PRODUCTION; ANTIBODY TITER; B LYMPHOCYTE ACTIVATION; BASOPHIL; CELL DIFFERENTIATION; CELL MIGRATION; DISEASE ASSOCIATION; EOSINOPHILIC ESOPHAGITIS; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN G4 RELATED DISEASE; LUPUS ERYTHEMATOSUS NEPHRITIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; ANIMAL; ANIMAL MODEL; IMMUNOLOGY; LUPUS NEPHRITIS; MOUSE; MULTIMODALITY CANCER THERAPY; PATHOLOGY;

ANIMALS; BASOPHILS; COMBINED MODALITY THERAPY; HUMANS; LUPUS NEPHRITIS; MICE; MODELS, ANIMAL;

EID: 84924205634     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2014.199     Document Type: Short Survey

References (10)

1. Charles, N., Hardwick, D., Daugas, E., Illei, G. G. & Rivera, J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat. Med. 16, 701-707 (2010).
2. Dema, B., et al. Immunoglobulin E plays an immunoregulatory role in lupus. J. Exp. Med. 211, 2159-2168 (2014).
3. Dema, B., et al. Autoreactive IgE is prevalent in systemic lupus erythematosus and is associated with increased disease activity and nephritis. PLoS ONE 9, e90424 (2014).
4. Otsuka, A., et al. Basophils are required for the induction of TH2 immunity to haptens and peptide antigens. Nat. Commun. 4, 1739 (2013).
5. Sharma, M., et al. Circulating human basophils lack the features of professional antigen presenting cells. Sci. Rep. 3, 1188 (2013).
6. Cassard, L., Jonsson, F., Arnaud, S. & Daeron, M. Fcγ receptors inhibit mouse and human basophil activation. J. Immunol. 189, 2995-3006 (2012).
7. Siracusa, M. C., et al. TSLP promotes interleukin 3-independent basophil haematopoiesis and type 2 inflammation. Nature 477, 229-233 (2011).
8. Noti, M., et al. Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nat. Med. 19, 1005-1013 (2013).
9. Watanabe, T., et al. Toll like receptor activation in basophils contributes to the development of IgG4-related disease. J. Gastroenterol. 48, 247-253 (2013).
10. Zhu, D., Kepley, C. L., Zhang, M., Zhang, K. & Saxon, A. A novel human immunoglobulin Fcγ-Fc? bifunctional fusion protein inhibits Fc?RI-mediated degranulation. Nat. Med. 8, 518-521 (2002