Characterization and quantification of innate lymphoid cell subsets in human lung

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  De Grove, Katrien C ^a   Provoost, Sharen ^a   Verhamme, Fien M ^a   Bracke, Ken R ^a   Joos, Guy F ^a   Maes, Tania ^a   Brusselle, Guy G ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 5; INTERLEUKIN 7 RECEPTOR; LYMPHOCYTE RECEPTOR; NATURAL CYTOTOXICITY RECEPTOR; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; CYTOKINE;

ADULT; AGED; ARTICLE; CELL SUBPOPULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FEMALE; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ALVEOLUS CELL; LYMPHOID CELL; MALE; PROTEIN ANALYSIS; BIOSYNTHESIS; IMMUNOLOGY; INNATE IMMUNITY; LUNG; LYMPHOCYTE SUBPOPULATION; MIDDLE AGED;

AGED; ANTIGENS, CD45; CYTOKINES; FEMALE; HUMANS; IMMUNITY, INNATE; LUNG; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED;

EID: 84954064749     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0145961     Document Type: Article

References (36)

1. Spits H, Di Santo JP. The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol 2011 Jan; 12(1):21-7. doi: 10.1038/ni.1962 PMID: 21113163
2. Walker JA, Barlow JL, McKenzie AN. Innate lymphoid cells-how did we miss them? Nat Rev Immunol 2013 Feb; 13(2):75-87. doi: 10.1038/nri3349 PMID: 23292121
3. Spits H, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, et al. Innate lymphoid cells-a proposal for uniform nomenclature. Nat Rev Immunol 2013 Feb; 13(2):145-9. doi: 10.1038/nri3365 PMID: 23348417
4. Hazenberg MD, Spits H. Human innate lymphoid cells. Blood 2014 Jul 31; 124(5):700-9. doi: 10.1182/blood-2013-11-427781 PMID: 24778151
5. Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol 2011 Nov; 12 (11):1045-54. doi: 10.1031/ni.2131 PMID: 21946417
6. Barnig C, Cernadas M, Dutile S, Liu X, Perrella MA, Kazani S, et al. Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci Transl Med 2013 Feb 27; 5(174):174ra26. doi: 10.1126/scitranslmed.3004812 PMID: 23447017
7. Kwon BI, Hong S, Shin K, Choi EH, Hwang JJ, Lee SH. Innate type 2 immunity is associated with eosinophilic pleural effusion in primary spontaneous pneumothorax. Am J Respir Crit Care Med 2013 Sep 1; 188(5):577-85. doi: 10.1164/rccm.201302-0295OC PMID: 23815597
8. Hams E, Armstrong ME, Barlow JL, Saunders SP, Schwartz C, Cooke G, et al. IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proc Natl Acad Sci U S A 2014 Jan 7; 111(1):367-72. doi: 10. 1073/pnas.1315854111 PMID: 24344271
9. Shaw JL, Fakhri S, Citardi MJ, Porter PC, Corry DB, Kheradmand F, et al. IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps. Am J Respir Crit Care Med 2013 Aug 15; 188(4):432-9. doi: 10.1164/rccm.201212-2227OC PMID: 23805875
10. Mjosberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B, et al. Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol 2011 Nov; 12(11):1055-62. doi: 10.1038/ni.2104 PMID: 21909091
11. Carrega P, Loiacono F, Di CE, Scaramuccia A, Mora M, Conte R, et al. NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures. Nat Commun 2015; 6:8280. doi: 10.1038/ncomms9280 PMID: 26395069
12. Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011 Sep 10; 378(9795):1015-26. doi: 10.1016/S0140-6736(11)60988-4 PMID: 21907865
13. Pauwels RA, Buist AS, Ma P, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary. Respir Care 2001 Aug; 46(8):798-825. PMID: 11463370
14. Van Pottelberge GR, Bracke KR, Van den Broeck S, Reinartz SM, van Drunen CM, Wouters EF, et al. Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD. Eur Respir J 2010 Oct; 36(4):781-91. doi: 10.1183/09031936.00140409 PMID: 20351031
15. Bernink JH, Peters CP, Munneke M, te Velde AA, Meijer SL, Weijer K, et al. Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues. Nat Immunol 2013 Mar; 14(3):221-9. doi: 10.1038/ni.2534 PMID: 23334791
16. Katchar K, Soderstrom K, Wahlstrom J, Eklund A, Grunewald J. Characterisation of natural killer cells and CD56+ T-cells in sarcoidosis patients. Eur Respir J 2005 Jul; 26(1):77-85. PMID: 15994392
17. Dyring-Andersen B, Geisler C, Agerbeck C, Lauritsen JP, Gudjonsdottir SD, Skov L, et al. Increased number and frequency of group 3 innate lymphoid cells in nonlesional psoriatic skin. Br J Dermatol 2014 Mar; 170(3):609-16. doi: 10.1111/bjd.12658 PMID: 24125475
18. Hoorweg K, Peters CP, Cornelissen F, Aparicio-Domingo P, Papazian N, Kazemier G, et al. Functional Differences between Human NKp44(-) and NKp44(+) RORC(+) Innate Lymphoid Cells. Front Immunol 2012; 3:72. doi: 10.3389/fimmu.2012.00072 PMID: 22566953
19. Klose CS, Kiss EA, Schwierzeck V, Ebert K, Hoyler T, d'Hargues Y, et al. A T-bet gradient controls the fate and function of CCR6-RORgammat+ innate lymphoid cells. Nature 2013 Feb 14; 494(7436):261-5. doi: 10.1038/nature11813 PMID: 23334414
20. Longman RS, Diehl GE, Victorio DA, Huh JR, Galan C, Miraldi ER, et al. CX(3)CR1(+) mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med 2014 Jul 28; 211(8):1571-83. doi: 10.1084/jem.20140678 PMID: 25024136
21. Mortha A, Chudnovskiy A, Hashimoto D, Bogunovic M, Spencer SP, Belkaid Y, et al. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science 2014 Mar 28; 343(6178):1249288. doi: 10.1126/science.1249288 PMID: 24625929
22. Cella M, Fuchs A, Vermi W, Facchetti F, Otero K, Lennerz JK, et al. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 2009 Feb 5; 457(7230):722-5. doi: 10. 1038/nature07537 PMID: 18978771
23. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004 Jun 24; 350(26):2645-53. PMID: 15215480
24. Brusselle GG, Demoor T, Bracke KR, Brandsma CA, Timens W. Lymphoid follicles in (very) severe COPD: beneficial or harmful? Eur Respir J 2009 Jul; 34(1):219-30. doi: 10.1183/09031936.00150208 PMID: 19567605
25. Roos AB, Sanden C, Mori M, Bjermer L, Stampfli MR, Erjefalt JS. IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis. Am J Respir Crit Care Med 2015 Jun 1; 191(11):1232-41. doi: 10.1164/rccm.201410-1861OC PMID: 25844618
26. Montaldo E, Juelke K, Romagnani C. Group 3 innate lymphoid cells (ILC3s): Origin, differentiation, and plasticity in humans and mice. Eur J Immunol 2015 Aug; 45(8):2171-82. doi: 10.1002/eji.201545598 PMID: 26031799
27. Turner JE, Morrison PJ, Wilhelm C, Wilson M, Ahlfors H, Renauld JC, et al. IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med 2013 Dec 16; 210(13):2951-65. doi: 10.1084/jem.20130071 PMID: 24249111
28. Barlow JL, Bellosi A, Hardman CS, Drynan LF, Wong SH, Cruickshank JP, et al. Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity. J Allergy Clin Immunol 2012 Jan; 129(1):191-8. doi: 10.1016/j.jaci.2011.09.041 PMID: 22079492
29. Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H. IL-33-responsive lineage-CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J Immunol 2012 Feb 1; 188(3):1503-13. doi: 10.4049/jimmunol.1102832 PMID: 22198948
30. Halim TY, Krauss RH, Sun AC, Takei F. Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 2012 Mar 23; 36(3):451-63. doi: 10.1016/j.immuni.2011.12.020 PMID: 22425247
31. Klein Wolterink RG, KleinJan A, van Nimwegen M, Bergen I, de Bruijn M, Levani Y, et al. Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma. Eur J Immunol 2012 May; 42(5):1106-16. doi: 10.1002/eji.201142018 PMID: 22539286
32. Kim HY, Chang YJ, Subramanian S, Lee HH, Albacker LA, Matangkasombut P, et al. Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity. J Allergy Clin Immunol 2012 Jan; 129(1):216-27. doi: 10.1016/j.jaci.2011.10.036 PMID: 22119406
33. Chang YJ, Kim HY, Albacker LA, Baumgarth N, McKenzie AN, Smith DE, et al. Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat Immunol 2011 Jul; 12(7):631-8. doi: 10.1038/ni.2045 PMID: 21623379
34. Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, et al. A large-scale, consortiumbased genomewide association study of asthma. N Engl J Med 2010 Sep 23; 363(13):1211-21. doi: 10.1056/NEJMoa0906312 PMID: 20860503
35. Brusselle GG, Maes T, Bracke KR. Eosinophils in the spotlight: Eosinophilic airway inflammation in nonallergic asthma. Nat Med 2013 Aug; 19(8):977-9. doi: 10.1038/nm.3300 PMID: 23921745
36. Kabata H, Moro K, Fukunaga K, Suzuki Y, Miyata J, Masaki K, et al. Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation. Nat Commun 2013; 4:2675. doi: 10.1038/ncomms3675 PMID: 24157859